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Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food
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Zeitschriftentitel: | Molecules |
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Personen und Körperschaften: | , , , , , , |
In: | Molecules, 24, 2019, 8, S. 1526 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
MDPI AG
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Schlagwörter: |
author_facet |
Wang, Yuzhen Liu, Huilin Zhang, Dianwei Liu, Jingmin Wang, Jing Wang, Shuo Sun, Baoguo Wang, Yuzhen Liu, Huilin Zhang, Dianwei Liu, Jingmin Wang, Jing Wang, Shuo Sun, Baoguo |
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author |
Wang, Yuzhen Liu, Huilin Zhang, Dianwei Liu, Jingmin Wang, Jing Wang, Shuo Sun, Baoguo |
spellingShingle |
Wang, Yuzhen Liu, Huilin Zhang, Dianwei Liu, Jingmin Wang, Jing Wang, Shuo Sun, Baoguo Molecules Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food Chemistry (miscellaneous) Analytical Chemistry Organic Chemistry Physical and Theoretical Chemistry Molecular Medicine Drug Discovery Pharmaceutical Science |
author_sort |
wang, yuzhen |
spelling |
Wang, Yuzhen Liu, Huilin Zhang, Dianwei Liu, Jingmin Wang, Jing Wang, Shuo Sun, Baoguo 1420-3049 MDPI AG Chemistry (miscellaneous) Analytical Chemistry Organic Chemistry Physical and Theoretical Chemistry Molecular Medicine Drug Discovery Pharmaceutical Science http://dx.doi.org/10.3390/molecules24081526 <jats:p>The inhibitory effects of baijiu vinasse extract and its phenolic acid compounds on the Nε-carboxymethyllysine (CML) formation from dairy food were investigated. The inhibitory effect of the baijiu vinasse extract against CML formation was 43.2% in the casein and D-glucose model, which used 6 mL of the 70% acetone extract at 60 °C for 40 min. The HPLC-MS/MS profiles of the vinasse extract indicated that vanillic, chlorogenic, p-coumaric, sinapic, caffeic, ferulic, and syringic acids were seven major phenolic acid compounds. Furthermore, the inhibitory mechanism of the phenolic acid compounds in the model of dairy food was discussed by the trapping and scavenging of glyoxal. The results of this study exhibit that seven major antioxidant phenolic acid compounds may play important roles in the antioxidant activity and CML inhibition of the vinasse extract in a model of dairy foods.</jats:p> Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food Molecules |
doi_str_mv |
10.3390/molecules24081526 |
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Chemie und Pharmazie Technik Physik Medizin |
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title |
Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food |
title_unstemmed |
Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food |
title_full |
Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food |
title_fullStr |
Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food |
title_full_unstemmed |
Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food |
title_short |
Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food |
title_sort |
baijiu vinasse extract scavenges glyoxal and inhibits the formation of nε-carboxymethyllysine in dairy food |
topic |
Chemistry (miscellaneous) Analytical Chemistry Organic Chemistry Physical and Theoretical Chemistry Molecular Medicine Drug Discovery Pharmaceutical Science |
url |
http://dx.doi.org/10.3390/molecules24081526 |
publishDate |
2019 |
physical |
1526 |
description |
<jats:p>The inhibitory effects of baijiu vinasse extract and its phenolic acid compounds on the Nε-carboxymethyllysine (CML) formation from dairy food were investigated. The inhibitory effect of the baijiu vinasse extract against CML formation was 43.2% in the casein and D-glucose model, which used 6 mL of the 70% acetone extract at 60 °C for 40 min. The HPLC-MS/MS profiles of the vinasse extract indicated that vanillic, chlorogenic, p-coumaric, sinapic, caffeic, ferulic, and syringic acids were seven major phenolic acid compounds. Furthermore, the inhibitory mechanism of the phenolic acid compounds in the model of dairy food was discussed by the trapping and scavenging of glyoxal. The results of this study exhibit that seven major antioxidant phenolic acid compounds may play important roles in the antioxidant activity and CML inhibition of the vinasse extract in a model of dairy foods.</jats:p> |
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author | Wang, Yuzhen, Liu, Huilin, Zhang, Dianwei, Liu, Jingmin, Wang, Jing, Wang, Shuo, Sun, Baoguo |
author_facet | Wang, Yuzhen, Liu, Huilin, Zhang, Dianwei, Liu, Jingmin, Wang, Jing, Wang, Shuo, Sun, Baoguo, Wang, Yuzhen, Liu, Huilin, Zhang, Dianwei, Liu, Jingmin, Wang, Jing, Wang, Shuo, Sun, Baoguo |
author_sort | wang, yuzhen |
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container_start_page | 0 |
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description | <jats:p>The inhibitory effects of baijiu vinasse extract and its phenolic acid compounds on the Nε-carboxymethyllysine (CML) formation from dairy food were investigated. The inhibitory effect of the baijiu vinasse extract against CML formation was 43.2% in the casein and D-glucose model, which used 6 mL of the 70% acetone extract at 60 °C for 40 min. The HPLC-MS/MS profiles of the vinasse extract indicated that vanillic, chlorogenic, p-coumaric, sinapic, caffeic, ferulic, and syringic acids were seven major phenolic acid compounds. Furthermore, the inhibitory mechanism of the phenolic acid compounds in the model of dairy food was discussed by the trapping and scavenging of glyoxal. The results of this study exhibit that seven major antioxidant phenolic acid compounds may play important roles in the antioxidant activity and CML inhibition of the vinasse extract in a model of dairy foods.</jats:p> |
doi_str_mv | 10.3390/molecules24081526 |
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series | Molecules |
source_id | 49 |
spelling | Wang, Yuzhen Liu, Huilin Zhang, Dianwei Liu, Jingmin Wang, Jing Wang, Shuo Sun, Baoguo 1420-3049 MDPI AG Chemistry (miscellaneous) Analytical Chemistry Organic Chemistry Physical and Theoretical Chemistry Molecular Medicine Drug Discovery Pharmaceutical Science http://dx.doi.org/10.3390/molecules24081526 <jats:p>The inhibitory effects of baijiu vinasse extract and its phenolic acid compounds on the Nε-carboxymethyllysine (CML) formation from dairy food were investigated. The inhibitory effect of the baijiu vinasse extract against CML formation was 43.2% in the casein and D-glucose model, which used 6 mL of the 70% acetone extract at 60 °C for 40 min. The HPLC-MS/MS profiles of the vinasse extract indicated that vanillic, chlorogenic, p-coumaric, sinapic, caffeic, ferulic, and syringic acids were seven major phenolic acid compounds. Furthermore, the inhibitory mechanism of the phenolic acid compounds in the model of dairy food was discussed by the trapping and scavenging of glyoxal. The results of this study exhibit that seven major antioxidant phenolic acid compounds may play important roles in the antioxidant activity and CML inhibition of the vinasse extract in a model of dairy foods.</jats:p> Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food Molecules |
spellingShingle | Wang, Yuzhen, Liu, Huilin, Zhang, Dianwei, Liu, Jingmin, Wang, Jing, Wang, Shuo, Sun, Baoguo, Molecules, Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food, Chemistry (miscellaneous), Analytical Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Molecular Medicine, Drug Discovery, Pharmaceutical Science |
title | Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food |
title_full | Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food |
title_fullStr | Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food |
title_full_unstemmed | Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food |
title_short | Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food |
title_sort | baijiu vinasse extract scavenges glyoxal and inhibits the formation of nε-carboxymethyllysine in dairy food |
title_unstemmed | Baijiu Vinasse Extract Scavenges Glyoxal and Inhibits the Formation of Nε-Carboxymethyllysine in Dairy Food |
topic | Chemistry (miscellaneous), Analytical Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Molecular Medicine, Drug Discovery, Pharmaceutical Science |
url | http://dx.doi.org/10.3390/molecules24081526 |