author_facet Zahiruddin, Sultan
Parveen, Abida
Khan, Washim
Ibrahim, Mohammad
Akhtar, Jamal
Khan, Asim Ali
Ansari, S H
Ahmad, Sayeed
Zahiruddin, Sultan
Parveen, Abida
Khan, Washim
Ibrahim, Mohammad
Akhtar, Jamal
Khan, Asim Ali
Ansari, S H
Ahmad, Sayeed
author Zahiruddin, Sultan
Parveen, Abida
Khan, Washim
Ibrahim, Mohammad
Akhtar, Jamal
Khan, Asim Ali
Ansari, S H
Ahmad, Sayeed
spellingShingle Zahiruddin, Sultan
Parveen, Abida
Khan, Washim
Ibrahim, Mohammad
Akhtar, Jamal
Khan, Asim Ali
Ansari, S H
Ahmad, Sayeed
Journal of AOAC INTERNATIONAL
Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
Pharmacology
Agronomy and Crop Science
Environmental Chemistry
Food Science
Analytical Chemistry
author_sort zahiruddin, sultan
spelling Zahiruddin, Sultan Parveen, Abida Khan, Washim Ibrahim, Mohammad Akhtar, Jamal Khan, Asim Ali Ansari, S H Ahmad, Sayeed 1060-3271 1944-7922 Oxford University Press (OUP) Pharmacology Agronomy and Crop Science Environmental Chemistry Food Science Analytical Chemistry http://dx.doi.org/10.5740/jaoacint.19-0230 <jats:title>Abstract</jats:title> <jats:p>Background: There is an increasing global demand for traditional medicines because of their efficacy, ease of availability, and few or no side effects. The Unani medicines have long been used in India and abroad for various disorders and diseases. Arqiyat (Arq; distillate) is one of the most widely used Unani formulation prepared by simple distillation from single or combination drugs. Objective: In the present investigation, an attempt has been made to generate data for quality control and stability testing of Arq formulations of the Unani Pharmacopeia of India that includes only three Arq formulations. Method: Arq-e-Nana (AeN), Arq-e-Gazar (AeG), and Arq-e-Brinjasif (AeB) were prepared through hydrodistillation. Quality control and stability analysis were performed by using HPTLC and GC-MS. Results: Dichloromethane extract of AeB showed maximum of 10 bands at different retardation factor values; however, there are 7 bands in AeN as well as in AeG. GC-MS analysis showed presence of 10 metabolites in AeG, 8 in AeN, and 9 in AeB. Stability studies showed that the shelf life of Arq formulations would be enhanced at refrigeration (5 ± 2°C) conditions. Conclusions: The present study highlights quality control and stability analysis of Arq formulations of Unani Pharmacopeia of India using HPTLC and GC-MS.</jats:p> Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS Journal of AOAC INTERNATIONAL
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title Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
title_unstemmed Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
title_full Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
title_fullStr Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
title_full_unstemmed Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
title_short Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
title_sort quality control and stability testing of arq formulations of unani pharmacopeia of india using hptlc and gc-ms
topic Pharmacology
Agronomy and Crop Science
Environmental Chemistry
Food Science
Analytical Chemistry
url http://dx.doi.org/10.5740/jaoacint.19-0230
publishDate 2020
physical 699-704
description <jats:title>Abstract</jats:title> <jats:p>Background: There is an increasing global demand for traditional medicines because of their efficacy, ease of availability, and few or no side effects. The Unani medicines have long been used in India and abroad for various disorders and diseases. Arqiyat (Arq; distillate) is one of the most widely used Unani formulation prepared by simple distillation from single or combination drugs. Objective: In the present investigation, an attempt has been made to generate data for quality control and stability testing of Arq formulations of the Unani Pharmacopeia of India that includes only three Arq formulations. Method: Arq-e-Nana (AeN), Arq-e-Gazar (AeG), and Arq-e-Brinjasif (AeB) were prepared through hydrodistillation. Quality control and stability analysis were performed by using HPTLC and GC-MS. Results: Dichloromethane extract of AeB showed maximum of 10 bands at different retardation factor values; however, there are 7 bands in AeN as well as in AeG. GC-MS analysis showed presence of 10 metabolites in AeG, 8 in AeN, and 9 in AeB. Stability studies showed that the shelf life of Arq formulations would be enhanced at refrigeration (5 ± 2°C) conditions. Conclusions: The present study highlights quality control and stability analysis of Arq formulations of Unani Pharmacopeia of India using HPTLC and GC-MS.</jats:p>
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author Zahiruddin, Sultan, Parveen, Abida, Khan, Washim, Ibrahim, Mohammad, Akhtar, Jamal, Khan, Asim Ali, Ansari, S H, Ahmad, Sayeed
author_facet Zahiruddin, Sultan, Parveen, Abida, Khan, Washim, Ibrahim, Mohammad, Akhtar, Jamal, Khan, Asim Ali, Ansari, S H, Ahmad, Sayeed, Zahiruddin, Sultan, Parveen, Abida, Khan, Washim, Ibrahim, Mohammad, Akhtar, Jamal, Khan, Asim Ali, Ansari, S H, Ahmad, Sayeed
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container_issue 3
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container_title Journal of AOAC INTERNATIONAL
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description <jats:title>Abstract</jats:title> <jats:p>Background: There is an increasing global demand for traditional medicines because of their efficacy, ease of availability, and few or no side effects. The Unani medicines have long been used in India and abroad for various disorders and diseases. Arqiyat (Arq; distillate) is one of the most widely used Unani formulation prepared by simple distillation from single or combination drugs. Objective: In the present investigation, an attempt has been made to generate data for quality control and stability testing of Arq formulations of the Unani Pharmacopeia of India that includes only three Arq formulations. Method: Arq-e-Nana (AeN), Arq-e-Gazar (AeG), and Arq-e-Brinjasif (AeB) were prepared through hydrodistillation. Quality control and stability analysis were performed by using HPTLC and GC-MS. Results: Dichloromethane extract of AeB showed maximum of 10 bands at different retardation factor values; however, there are 7 bands in AeN as well as in AeG. GC-MS analysis showed presence of 10 metabolites in AeG, 8 in AeN, and 9 in AeB. Stability studies showed that the shelf life of Arq formulations would be enhanced at refrigeration (5 ± 2°C) conditions. Conclusions: The present study highlights quality control and stability analysis of Arq formulations of Unani Pharmacopeia of India using HPTLC and GC-MS.</jats:p>
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spelling Zahiruddin, Sultan Parveen, Abida Khan, Washim Ibrahim, Mohammad Akhtar, Jamal Khan, Asim Ali Ansari, S H Ahmad, Sayeed 1060-3271 1944-7922 Oxford University Press (OUP) Pharmacology Agronomy and Crop Science Environmental Chemistry Food Science Analytical Chemistry http://dx.doi.org/10.5740/jaoacint.19-0230 <jats:title>Abstract</jats:title> <jats:p>Background: There is an increasing global demand for traditional medicines because of their efficacy, ease of availability, and few or no side effects. The Unani medicines have long been used in India and abroad for various disorders and diseases. Arqiyat (Arq; distillate) is one of the most widely used Unani formulation prepared by simple distillation from single or combination drugs. Objective: In the present investigation, an attempt has been made to generate data for quality control and stability testing of Arq formulations of the Unani Pharmacopeia of India that includes only three Arq formulations. Method: Arq-e-Nana (AeN), Arq-e-Gazar (AeG), and Arq-e-Brinjasif (AeB) were prepared through hydrodistillation. Quality control and stability analysis were performed by using HPTLC and GC-MS. Results: Dichloromethane extract of AeB showed maximum of 10 bands at different retardation factor values; however, there are 7 bands in AeN as well as in AeG. GC-MS analysis showed presence of 10 metabolites in AeG, 8 in AeN, and 9 in AeB. Stability studies showed that the shelf life of Arq formulations would be enhanced at refrigeration (5 ± 2°C) conditions. Conclusions: The present study highlights quality control and stability analysis of Arq formulations of Unani Pharmacopeia of India using HPTLC and GC-MS.</jats:p> Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS Journal of AOAC INTERNATIONAL
spellingShingle Zahiruddin, Sultan, Parveen, Abida, Khan, Washim, Ibrahim, Mohammad, Akhtar, Jamal, Khan, Asim Ali, Ansari, S H, Ahmad, Sayeed, Journal of AOAC INTERNATIONAL, Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS, Pharmacology, Agronomy and Crop Science, Environmental Chemistry, Food Science, Analytical Chemistry
title Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
title_full Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
title_fullStr Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
title_full_unstemmed Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
title_short Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
title_sort quality control and stability testing of arq formulations of unani pharmacopeia of india using hptlc and gc-ms
title_unstemmed Quality Control and Stability Testing of Arq Formulations of Unani Pharmacopeia of India Using HPTLC and GC-MS
topic Pharmacology, Agronomy and Crop Science, Environmental Chemistry, Food Science, Analytical Chemistry
url http://dx.doi.org/10.5740/jaoacint.19-0230