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Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds
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| Zeitschriftentitel: | Key Engineering Materials |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , |
| In: | Key Engineering Materials, 758, 2017, S. 132-137 |
| Format: | E-Article |
| Sprache: | Unbestimmt |
| veröffentlicht: |
Trans Tech Publications, Ltd.
|
| Schlagwörter: |
| author_facet |
Scalera, Francesca Gervaso, Francesca Palazzo, Barbara Scialla, Stefania Izzo, Daniela Cancelli, Nadia Barca, Amilcare Padmanabhan, Sanosh Kunjalukkal Sannino, Alessandro Piconi, Corrado Scalera, Francesca Gervaso, Francesca Palazzo, Barbara Scialla, Stefania Izzo, Daniela Cancelli, Nadia Barca, Amilcare Padmanabhan, Sanosh Kunjalukkal Sannino, Alessandro Piconi, Corrado |
|---|---|
| author |
Scalera, Francesca Gervaso, Francesca Palazzo, Barbara Scialla, Stefania Izzo, Daniela Cancelli, Nadia Barca, Amilcare Padmanabhan, Sanosh Kunjalukkal Sannino, Alessandro Piconi, Corrado |
| spellingShingle |
Scalera, Francesca Gervaso, Francesca Palazzo, Barbara Scialla, Stefania Izzo, Daniela Cancelli, Nadia Barca, Amilcare Padmanabhan, Sanosh Kunjalukkal Sannino, Alessandro Piconi, Corrado Key Engineering Materials Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds Mechanical Engineering Mechanics of Materials General Materials Science |
| author_sort |
scalera, francesca |
| spelling |
Scalera, Francesca Gervaso, Francesca Palazzo, Barbara Scialla, Stefania Izzo, Daniela Cancelli, Nadia Barca, Amilcare Padmanabhan, Sanosh Kunjalukkal Sannino, Alessandro Piconi, Corrado 1662-9795 Trans Tech Publications, Ltd. Mechanical Engineering Mechanics of Materials General Materials Science http://dx.doi.org/10.4028/www.scientific.net/kem.758.132 <jats:p>Two different approaches are proposed in this study to enhance the bioactivity of hydroxyapatite-based scaffolds for bone tissue regeneration. The first method consists in a structural modification of Hydroxyapatite (HA) through doping it with Magnesium (1,3% wt) while the second one in using HA in combination with a calcium silicate, i.e. Wollastonite (WS), to form a composite bioceramic. Scaffolds with high and strongly interconnected porosity (pores ranging from 300 to 800 µm) were produced throughout both procedures. Higher mechanical properties in compression were obtained when the composite Ws/HA bioceramic was adopted. That one showed a weight loss after 6 months in physiological solution seven times higher than doped HA. Preliminary in vitro tests highlighted that both kinds of scaffold allowed the adhesion of MG63, without significant differences in terms of vitality, indicating a good biocompatibility of both used biomaterials.</jats:p> Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds Key Engineering Materials |
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| title |
Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds |
| title_unstemmed |
Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds |
| title_full |
Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds |
| title_fullStr |
Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds |
| title_full_unstemmed |
Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds |
| title_short |
Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds |
| title_sort |
strategies to improve bioactivity of hydroxyapatite bone scaffolds |
| topic |
Mechanical Engineering Mechanics of Materials General Materials Science |
| url |
http://dx.doi.org/10.4028/www.scientific.net/kem.758.132 |
| publishDate |
2017 |
| physical |
132-137 |
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<jats:p>Two different approaches are proposed in this study to enhance the bioactivity of hydroxyapatite-based scaffolds for bone tissue regeneration. The first method consists in a structural modification of Hydroxyapatite (HA) through doping it with Magnesium (1,3% wt) while the second one in using HA in combination with a calcium silicate, i.e. Wollastonite (WS), to form a composite bioceramic. Scaffolds with high and strongly interconnected porosity (pores ranging from 300 to 800 µm) were produced throughout both procedures. Higher mechanical properties in compression were obtained when the composite Ws/HA bioceramic was adopted. That one showed a weight loss after 6 months in physiological solution seven times higher than doped HA. Preliminary in vitro tests highlighted that both kinds of scaffold allowed the adhesion of MG63, without significant differences in terms of vitality, indicating a good biocompatibility of both used biomaterials.</jats:p> |
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| author | Scalera, Francesca, Gervaso, Francesca, Palazzo, Barbara, Scialla, Stefania, Izzo, Daniela, Cancelli, Nadia, Barca, Amilcare, Padmanabhan, Sanosh Kunjalukkal, Sannino, Alessandro, Piconi, Corrado |
| author_facet | Scalera, Francesca, Gervaso, Francesca, Palazzo, Barbara, Scialla, Stefania, Izzo, Daniela, Cancelli, Nadia, Barca, Amilcare, Padmanabhan, Sanosh Kunjalukkal, Sannino, Alessandro, Piconi, Corrado, Scalera, Francesca, Gervaso, Francesca, Palazzo, Barbara, Scialla, Stefania, Izzo, Daniela, Cancelli, Nadia, Barca, Amilcare, Padmanabhan, Sanosh Kunjalukkal, Sannino, Alessandro, Piconi, Corrado |
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| description | <jats:p>Two different approaches are proposed in this study to enhance the bioactivity of hydroxyapatite-based scaffolds for bone tissue regeneration. The first method consists in a structural modification of Hydroxyapatite (HA) through doping it with Magnesium (1,3% wt) while the second one in using HA in combination with a calcium silicate, i.e. Wollastonite (WS), to form a composite bioceramic. Scaffolds with high and strongly interconnected porosity (pores ranging from 300 to 800 µm) were produced throughout both procedures. Higher mechanical properties in compression were obtained when the composite Ws/HA bioceramic was adopted. That one showed a weight loss after 6 months in physiological solution seven times higher than doped HA. Preliminary in vitro tests highlighted that both kinds of scaffold allowed the adhesion of MG63, without significant differences in terms of vitality, indicating a good biocompatibility of both used biomaterials.</jats:p> |
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| imprint_str_mv | Trans Tech Publications, Ltd., 2017 |
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| physical | 132-137 |
| publishDate | 2017 |
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| series | Key Engineering Materials |
| source_id | 49 |
| spelling | Scalera, Francesca Gervaso, Francesca Palazzo, Barbara Scialla, Stefania Izzo, Daniela Cancelli, Nadia Barca, Amilcare Padmanabhan, Sanosh Kunjalukkal Sannino, Alessandro Piconi, Corrado 1662-9795 Trans Tech Publications, Ltd. Mechanical Engineering Mechanics of Materials General Materials Science http://dx.doi.org/10.4028/www.scientific.net/kem.758.132 <jats:p>Two different approaches are proposed in this study to enhance the bioactivity of hydroxyapatite-based scaffolds for bone tissue regeneration. The first method consists in a structural modification of Hydroxyapatite (HA) through doping it with Magnesium (1,3% wt) while the second one in using HA in combination with a calcium silicate, i.e. Wollastonite (WS), to form a composite bioceramic. Scaffolds with high and strongly interconnected porosity (pores ranging from 300 to 800 µm) were produced throughout both procedures. Higher mechanical properties in compression were obtained when the composite Ws/HA bioceramic was adopted. That one showed a weight loss after 6 months in physiological solution seven times higher than doped HA. Preliminary in vitro tests highlighted that both kinds of scaffold allowed the adhesion of MG63, without significant differences in terms of vitality, indicating a good biocompatibility of both used biomaterials.</jats:p> Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds Key Engineering Materials |
| spellingShingle | Scalera, Francesca, Gervaso, Francesca, Palazzo, Barbara, Scialla, Stefania, Izzo, Daniela, Cancelli, Nadia, Barca, Amilcare, Padmanabhan, Sanosh Kunjalukkal, Sannino, Alessandro, Piconi, Corrado, Key Engineering Materials, Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds, Mechanical Engineering, Mechanics of Materials, General Materials Science |
| title | Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds |
| title_full | Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds |
| title_fullStr | Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds |
| title_full_unstemmed | Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds |
| title_short | Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds |
| title_sort | strategies to improve bioactivity of hydroxyapatite bone scaffolds |
| title_unstemmed | Strategies to Improve Bioactivity of Hydroxyapatite Bone Scaffolds |
| topic | Mechanical Engineering, Mechanics of Materials, General Materials Science |
| url | http://dx.doi.org/10.4028/www.scientific.net/kem.758.132 |