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One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions
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| Zeitschriftentitel: | Molecules |
|---|---|
| Personen und Körperschaften: | , , , , , , |
| In: | Molecules, 24, 2019, 3, S. 601 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
MDPI AG
|
| Schlagwörter: |
| author_facet |
Ma, Xiaoming Zhang, Xiaofeng Qiu, Weiqi Zhang, Wensheng Wan, Bruce Evans, Jason Zhang, Wei Ma, Xiaoming Zhang, Xiaofeng Qiu, Weiqi Zhang, Wensheng Wan, Bruce Evans, Jason Zhang, Wei |
|---|---|
| author |
Ma, Xiaoming Zhang, Xiaofeng Qiu, Weiqi Zhang, Wensheng Wan, Bruce Evans, Jason Zhang, Wei |
| spellingShingle |
Ma, Xiaoming Zhang, Xiaofeng Qiu, Weiqi Zhang, Wensheng Wan, Bruce Evans, Jason Zhang, Wei Molecules One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions Chemistry (miscellaneous) Analytical Chemistry Organic Chemistry Physical and Theoretical Chemistry Molecular Medicine Drug Discovery Pharmaceutical Science |
| author_sort |
ma, xiaoming |
| spelling |
Ma, Xiaoming Zhang, Xiaofeng Qiu, Weiqi Zhang, Wensheng Wan, Bruce Evans, Jason Zhang, Wei 1420-3049 MDPI AG Chemistry (miscellaneous) Analytical Chemistry Organic Chemistry Physical and Theoretical Chemistry Molecular Medicine Drug Discovery Pharmaceutical Science http://dx.doi.org/10.3390/molecules24030601 <jats:p>A one-pot synthesis of triazolobenzodiazepine-containing polycyclic compounds is introduced. The reaction process involves a decarboxylative three-component [3 + 2] cycloaddition of nonstabilized azomethine ylides, N-propargylation, and intramolecular click reactions.</jats:p> One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions Molecules |
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10.3390/molecules24030601 |
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| title |
One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions |
| title_unstemmed |
One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions |
| title_full |
One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions |
| title_fullStr |
One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions |
| title_full_unstemmed |
One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions |
| title_short |
One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions |
| title_sort |
one-pot synthesis of triazolobenzodiazepines through decarboxylative [3 + 2] cycloaddition of nonstabilized azomethine ylides and cu-free click reactions |
| topic |
Chemistry (miscellaneous) Analytical Chemistry Organic Chemistry Physical and Theoretical Chemistry Molecular Medicine Drug Discovery Pharmaceutical Science |
| url |
http://dx.doi.org/10.3390/molecules24030601 |
| publishDate |
2019 |
| physical |
601 |
| description |
<jats:p>A one-pot synthesis of triazolobenzodiazepine-containing polycyclic compounds is introduced. The reaction process involves a decarboxylative three-component [3 + 2] cycloaddition of nonstabilized azomethine ylides, N-propargylation, and intramolecular click reactions.</jats:p> |
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| author | Ma, Xiaoming, Zhang, Xiaofeng, Qiu, Weiqi, Zhang, Wensheng, Wan, Bruce, Evans, Jason, Zhang, Wei |
| author_facet | Ma, Xiaoming, Zhang, Xiaofeng, Qiu, Weiqi, Zhang, Wensheng, Wan, Bruce, Evans, Jason, Zhang, Wei, Ma, Xiaoming, Zhang, Xiaofeng, Qiu, Weiqi, Zhang, Wensheng, Wan, Bruce, Evans, Jason, Zhang, Wei |
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| description | <jats:p>A one-pot synthesis of triazolobenzodiazepine-containing polycyclic compounds is introduced. The reaction process involves a decarboxylative three-component [3 + 2] cycloaddition of nonstabilized azomethine ylides, N-propargylation, and intramolecular click reactions.</jats:p> |
| doi_str_mv | 10.3390/molecules24030601 |
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| imprint | MDPI AG, 2019 |
| imprint_str_mv | MDPI AG, 2019 |
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| physical | 601 |
| publishDate | 2019 |
| publishDateSort | 2019 |
| publisher | MDPI AG |
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| series | Molecules |
| source_id | 49 |
| spelling | Ma, Xiaoming Zhang, Xiaofeng Qiu, Weiqi Zhang, Wensheng Wan, Bruce Evans, Jason Zhang, Wei 1420-3049 MDPI AG Chemistry (miscellaneous) Analytical Chemistry Organic Chemistry Physical and Theoretical Chemistry Molecular Medicine Drug Discovery Pharmaceutical Science http://dx.doi.org/10.3390/molecules24030601 <jats:p>A one-pot synthesis of triazolobenzodiazepine-containing polycyclic compounds is introduced. The reaction process involves a decarboxylative three-component [3 + 2] cycloaddition of nonstabilized azomethine ylides, N-propargylation, and intramolecular click reactions.</jats:p> One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions Molecules |
| spellingShingle | Ma, Xiaoming, Zhang, Xiaofeng, Qiu, Weiqi, Zhang, Wensheng, Wan, Bruce, Evans, Jason, Zhang, Wei, Molecules, One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions, Chemistry (miscellaneous), Analytical Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Molecular Medicine, Drug Discovery, Pharmaceutical Science |
| title | One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions |
| title_full | One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions |
| title_fullStr | One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions |
| title_full_unstemmed | One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions |
| title_short | One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions |
| title_sort | one-pot synthesis of triazolobenzodiazepines through decarboxylative [3 + 2] cycloaddition of nonstabilized azomethine ylides and cu-free click reactions |
| title_unstemmed | One-Pot Synthesis of Triazolobenzodiazepines Through Decarboxylative [3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides and Cu-Free Click Reactions |
| topic | Chemistry (miscellaneous), Analytical Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Molecular Medicine, Drug Discovery, Pharmaceutical Science |
| url | http://dx.doi.org/10.3390/molecules24030601 |