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A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218
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| Zeitschriftentitel: | Molecules |
|---|---|
| Personen und Körperschaften: | , , , , , |
| In: | Molecules, 24, 2019, 9, S. 1686 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
MDPI AG
|
| Schlagwörter: |
| author_facet |
Huang, Jingxia She, Jianglian Yang, Xiliang Liu, Juan Zhou, Xuefeng Yang, Bin Huang, Jingxia She, Jianglian Yang, Xiliang Liu, Juan Zhou, Xuefeng Yang, Bin |
|---|---|
| author |
Huang, Jingxia She, Jianglian Yang, Xiliang Liu, Juan Zhou, Xuefeng Yang, Bin |
| spellingShingle |
Huang, Jingxia She, Jianglian Yang, Xiliang Liu, Juan Zhou, Xuefeng Yang, Bin Molecules A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 Chemistry (miscellaneous) Analytical Chemistry Organic Chemistry Physical and Theoretical Chemistry Molecular Medicine Drug Discovery Pharmaceutical Science |
| author_sort |
huang, jingxia |
| spelling |
Huang, Jingxia She, Jianglian Yang, Xiliang Liu, Juan Zhou, Xuefeng Yang, Bin 1420-3049 MDPI AG Chemistry (miscellaneous) Analytical Chemistry Organic Chemistry Physical and Theoretical Chemistry Molecular Medicine Drug Discovery Pharmaceutical Science http://dx.doi.org/10.3390/molecules24091686 <jats:p>A new macrodiolide, mangrovlide A (1) and two new polycyclic chromones, penixanthones C (2) and D (3), as well as four other known compounds (4–7), have been isolated from the mangrove sediment derived fungus Penicillium sp. SCSIO041218, cultured in the 0.25% NaCl rice substrate. The structures of the new compounds were determined by analysis of the NMR and MS spectroscopic data. Compound 1 possesses a 10-membered macrodiolide unit, while 2 and 3 are chromones with an unprecedented 6/6/6/5 polycyclic skeleton. Compounds 1–7 were evaluated for their cytotoxicities, while all the compounds displayed weak or no activity.</jats:p> A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 Molecules |
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| title |
A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 |
| title_unstemmed |
A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 |
| title_full |
A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 |
| title_fullStr |
A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 |
| title_full_unstemmed |
A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 |
| title_short |
A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 |
| title_sort |
a new macrodiolide and two new polycyclic chromones from the fungus penicillium sp. scsio041218 |
| topic |
Chemistry (miscellaneous) Analytical Chemistry Organic Chemistry Physical and Theoretical Chemistry Molecular Medicine Drug Discovery Pharmaceutical Science |
| url |
http://dx.doi.org/10.3390/molecules24091686 |
| publishDate |
2019 |
| physical |
1686 |
| description |
<jats:p>A new macrodiolide, mangrovlide A (1) and two new polycyclic chromones, penixanthones C (2) and D (3), as well as four other known compounds (4–7), have been isolated from the mangrove sediment derived fungus Penicillium sp. SCSIO041218, cultured in the 0.25% NaCl rice substrate. The structures of the new compounds were determined by analysis of the NMR and MS spectroscopic data. Compound 1 possesses a 10-membered macrodiolide unit, while 2 and 3 are chromones with an unprecedented 6/6/6/5 polycyclic skeleton. Compounds 1–7 were evaluated for their cytotoxicities, while all the compounds displayed weak or no activity.</jats:p> |
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| author | Huang, Jingxia, She, Jianglian, Yang, Xiliang, Liu, Juan, Zhou, Xuefeng, Yang, Bin |
| author_facet | Huang, Jingxia, She, Jianglian, Yang, Xiliang, Liu, Juan, Zhou, Xuefeng, Yang, Bin, Huang, Jingxia, She, Jianglian, Yang, Xiliang, Liu, Juan, Zhou, Xuefeng, Yang, Bin |
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| description | <jats:p>A new macrodiolide, mangrovlide A (1) and two new polycyclic chromones, penixanthones C (2) and D (3), as well as four other known compounds (4–7), have been isolated from the mangrove sediment derived fungus Penicillium sp. SCSIO041218, cultured in the 0.25% NaCl rice substrate. The structures of the new compounds were determined by analysis of the NMR and MS spectroscopic data. Compound 1 possesses a 10-membered macrodiolide unit, while 2 and 3 are chromones with an unprecedented 6/6/6/5 polycyclic skeleton. Compounds 1–7 were evaluated for their cytotoxicities, while all the compounds displayed weak or no activity.</jats:p> |
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| physical | 1686 |
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| spelling | Huang, Jingxia She, Jianglian Yang, Xiliang Liu, Juan Zhou, Xuefeng Yang, Bin 1420-3049 MDPI AG Chemistry (miscellaneous) Analytical Chemistry Organic Chemistry Physical and Theoretical Chemistry Molecular Medicine Drug Discovery Pharmaceutical Science http://dx.doi.org/10.3390/molecules24091686 <jats:p>A new macrodiolide, mangrovlide A (1) and two new polycyclic chromones, penixanthones C (2) and D (3), as well as four other known compounds (4–7), have been isolated from the mangrove sediment derived fungus Penicillium sp. SCSIO041218, cultured in the 0.25% NaCl rice substrate. The structures of the new compounds were determined by analysis of the NMR and MS spectroscopic data. Compound 1 possesses a 10-membered macrodiolide unit, while 2 and 3 are chromones with an unprecedented 6/6/6/5 polycyclic skeleton. Compounds 1–7 were evaluated for their cytotoxicities, while all the compounds displayed weak or no activity.</jats:p> A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 Molecules |
| spellingShingle | Huang, Jingxia, She, Jianglian, Yang, Xiliang, Liu, Juan, Zhou, Xuefeng, Yang, Bin, Molecules, A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218, Chemistry (miscellaneous), Analytical Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Molecular Medicine, Drug Discovery, Pharmaceutical Science |
| title | A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 |
| title_full | A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 |
| title_fullStr | A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 |
| title_full_unstemmed | A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 |
| title_short | A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 |
| title_sort | a new macrodiolide and two new polycyclic chromones from the fungus penicillium sp. scsio041218 |
| title_unstemmed | A New Macrodiolide and Two New Polycyclic Chromones from the Fungus Penicillium sp. SCSIO041218 |
| topic | Chemistry (miscellaneous), Analytical Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Molecular Medicine, Drug Discovery, Pharmaceutical Science |
| url | http://dx.doi.org/10.3390/molecules24091686 |