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Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure
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Zeitschriftentitel: | Journal of Medical Biochemistry |
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Personen und Körperschaften: | , , , , , , , |
In: | Journal of Medical Biochemistry, 38, 2019, 4, S. 452-460 |
Format: | E-Article |
Sprache: | Unbestimmt |
veröffentlicht: |
Centre for Evaluation in Education and Science (CEON/CEES)
|
author_facet |
Turcato, Gianni Sanchis-Gomar, Fabian Cervellin, Gianfranco Zorzi, Elisabetta Sivero, Valentina Salvagno, Gian Luca Tenci, Andrea Lippi, Giuseppe Turcato, Gianni Sanchis-Gomar, Fabian Cervellin, Gianfranco Zorzi, Elisabetta Sivero, Valentina Salvagno, Gian Luca Tenci, Andrea Lippi, Giuseppe |
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author |
Turcato, Gianni Sanchis-Gomar, Fabian Cervellin, Gianfranco Zorzi, Elisabetta Sivero, Valentina Salvagno, Gian Luca Tenci, Andrea Lippi, Giuseppe |
spellingShingle |
Turcato, Gianni Sanchis-Gomar, Fabian Cervellin, Gianfranco Zorzi, Elisabetta Sivero, Valentina Salvagno, Gian Luca Tenci, Andrea Lippi, Giuseppe Journal of Medical Biochemistry Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
author_sort |
turcato, gianni |
spelling |
Turcato, Gianni Sanchis-Gomar, Fabian Cervellin, Gianfranco Zorzi, Elisabetta Sivero, Valentina Salvagno, Gian Luca Tenci, Andrea Lippi, Giuseppe 1452-8266 Centre for Evaluation in Education and Science (CEON/CEES) http://dx.doi.org/10.2478/jomb-2018-0044 <jats:title>Summary</jats:title> <jats:sec id="j_jomb-2018-0044_s_005"> <jats:title>Background</jats:title> <jats:p>To investigate the association between both neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) and 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure (ADHF).</jats:p> </jats:sec> <jats:sec id="j_jomb-2018-0044_s_006"> <jats:title>Methods</jats:title> <jats:p>439 patients admitted to emergency department (ED) for an episode of ADHF. Clinical history, demographic, clinical and laboratory data recorded at ED admission and then correlated with 30-day mortality.</jats:p> </jats:sec> <jats:sec id="j_jomb-2018-0044_s_007"> <jats:title>Results</jats:title> <jats:p>45/439 (10.3%) patients died within 30 days from ED admission. The median values of NLR (4.1 vs 11.7) and PLR (159.1 vs 285.9) were significantly lower in survivors than in patients who died. The area under the ROC curve of NLR was significantly higher than that of the neutrophil count (0.76 vs 0.59; p<0.001), whilst the AUC of PLR was significantly better than that of the platelet count (0.71 vs 0.51; p<0.001). In univariate analysis, both NLR and PLR were significantly associated with 30-day. In the fully-adjusted multivariate model, NLR (odds ratio, 3.63) and PLR (odds ratio, 3.22) remained independently associated with 30-day mortality after ED admission.</jats:p> </jats:sec> <jats:sec id="j_jomb-2018-0044_s_008"> <jats:title>Conclusions</jats:title> <jats:p>Routine assessment of NLR and PLR at ED admission may be a valuable aid to complement other conventional measures for assessing the medium-short risk of ADHF patients.</jats:p></jats:sec> Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure Journal of Medical Biochemistry |
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10.2478/jomb-2018-0044 |
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Centre for Evaluation in Education and Science (CEON/CEES), 2019 |
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Journal of Medical Biochemistry |
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49 |
title |
Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title_unstemmed |
Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title_full |
Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title_fullStr |
Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title_full_unstemmed |
Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title_short |
Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title_sort |
evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
url |
http://dx.doi.org/10.2478/jomb-2018-0044 |
publishDate |
2019 |
physical |
452-460 |
description |
<jats:title>Summary</jats:title>
<jats:sec id="j_jomb-2018-0044_s_005">
<jats:title>Background</jats:title>
<jats:p>To investigate the association between both neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) and 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure (ADHF).</jats:p>
</jats:sec>
<jats:sec id="j_jomb-2018-0044_s_006">
<jats:title>Methods</jats:title>
<jats:p>439 patients admitted to emergency department (ED) for an episode of ADHF. Clinical history, demographic, clinical and laboratory data recorded at ED admission and then correlated with 30-day mortality.</jats:p>
</jats:sec>
<jats:sec id="j_jomb-2018-0044_s_007">
<jats:title>Results</jats:title>
<jats:p>45/439 (10.3%) patients died within 30 days from ED admission. The median values of NLR (4.1 vs 11.7) and PLR (159.1 vs 285.9) were significantly lower in survivors than in patients who died. The area under the ROC curve of NLR was significantly higher than that of the neutrophil count (0.76 vs 0.59; p<0.001), whilst the AUC of PLR was significantly better than that of the platelet count (0.71 vs 0.51; p<0.001). In univariate analysis, both NLR and PLR were significantly associated with 30-day. In the fully-adjusted multivariate model, NLR (odds ratio, 3.63) and PLR (odds ratio, 3.22) remained independently associated with 30-day mortality after ED admission.</jats:p>
</jats:sec>
<jats:sec id="j_jomb-2018-0044_s_008">
<jats:title>Conclusions</jats:title>
<jats:p>Routine assessment of NLR and PLR at ED admission may be a valuable aid to complement other conventional measures for assessing the medium-short risk of ADHF patients.</jats:p></jats:sec> |
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author | Turcato, Gianni, Sanchis-Gomar, Fabian, Cervellin, Gianfranco, Zorzi, Elisabetta, Sivero, Valentina, Salvagno, Gian Luca, Tenci, Andrea, Lippi, Giuseppe |
author_facet | Turcato, Gianni, Sanchis-Gomar, Fabian, Cervellin, Gianfranco, Zorzi, Elisabetta, Sivero, Valentina, Salvagno, Gian Luca, Tenci, Andrea, Lippi, Giuseppe, Turcato, Gianni, Sanchis-Gomar, Fabian, Cervellin, Gianfranco, Zorzi, Elisabetta, Sivero, Valentina, Salvagno, Gian Luca, Tenci, Andrea, Lippi, Giuseppe |
author_sort | turcato, gianni |
container_issue | 4 |
container_start_page | 452 |
container_title | Journal of Medical Biochemistry |
container_volume | 38 |
description | <jats:title>Summary</jats:title> <jats:sec id="j_jomb-2018-0044_s_005"> <jats:title>Background</jats:title> <jats:p>To investigate the association between both neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) and 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure (ADHF).</jats:p> </jats:sec> <jats:sec id="j_jomb-2018-0044_s_006"> <jats:title>Methods</jats:title> <jats:p>439 patients admitted to emergency department (ED) for an episode of ADHF. Clinical history, demographic, clinical and laboratory data recorded at ED admission and then correlated with 30-day mortality.</jats:p> </jats:sec> <jats:sec id="j_jomb-2018-0044_s_007"> <jats:title>Results</jats:title> <jats:p>45/439 (10.3%) patients died within 30 days from ED admission. The median values of NLR (4.1 vs 11.7) and PLR (159.1 vs 285.9) were significantly lower in survivors than in patients who died. The area under the ROC curve of NLR was significantly higher than that of the neutrophil count (0.76 vs 0.59; p<0.001), whilst the AUC of PLR was significantly better than that of the platelet count (0.71 vs 0.51; p<0.001). In univariate analysis, both NLR and PLR were significantly associated with 30-day. In the fully-adjusted multivariate model, NLR (odds ratio, 3.63) and PLR (odds ratio, 3.22) remained independently associated with 30-day mortality after ED admission.</jats:p> </jats:sec> <jats:sec id="j_jomb-2018-0044_s_008"> <jats:title>Conclusions</jats:title> <jats:p>Routine assessment of NLR and PLR at ED admission may be a valuable aid to complement other conventional measures for assessing the medium-short risk of ADHF patients.</jats:p></jats:sec> |
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spelling | Turcato, Gianni Sanchis-Gomar, Fabian Cervellin, Gianfranco Zorzi, Elisabetta Sivero, Valentina Salvagno, Gian Luca Tenci, Andrea Lippi, Giuseppe 1452-8266 Centre for Evaluation in Education and Science (CEON/CEES) http://dx.doi.org/10.2478/jomb-2018-0044 <jats:title>Summary</jats:title> <jats:sec id="j_jomb-2018-0044_s_005"> <jats:title>Background</jats:title> <jats:p>To investigate the association between both neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) and 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure (ADHF).</jats:p> </jats:sec> <jats:sec id="j_jomb-2018-0044_s_006"> <jats:title>Methods</jats:title> <jats:p>439 patients admitted to emergency department (ED) for an episode of ADHF. Clinical history, demographic, clinical and laboratory data recorded at ED admission and then correlated with 30-day mortality.</jats:p> </jats:sec> <jats:sec id="j_jomb-2018-0044_s_007"> <jats:title>Results</jats:title> <jats:p>45/439 (10.3%) patients died within 30 days from ED admission. The median values of NLR (4.1 vs 11.7) and PLR (159.1 vs 285.9) were significantly lower in survivors than in patients who died. The area under the ROC curve of NLR was significantly higher than that of the neutrophil count (0.76 vs 0.59; p<0.001), whilst the AUC of PLR was significantly better than that of the platelet count (0.71 vs 0.51; p<0.001). In univariate analysis, both NLR and PLR were significantly associated with 30-day. In the fully-adjusted multivariate model, NLR (odds ratio, 3.63) and PLR (odds ratio, 3.22) remained independently associated with 30-day mortality after ED admission.</jats:p> </jats:sec> <jats:sec id="j_jomb-2018-0044_s_008"> <jats:title>Conclusions</jats:title> <jats:p>Routine assessment of NLR and PLR at ED admission may be a valuable aid to complement other conventional measures for assessing the medium-short risk of ADHF patients.</jats:p></jats:sec> Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure Journal of Medical Biochemistry |
spellingShingle | Turcato, Gianni, Sanchis-Gomar, Fabian, Cervellin, Gianfranco, Zorzi, Elisabetta, Sivero, Valentina, Salvagno, Gian Luca, Tenci, Andrea, Lippi, Giuseppe, Journal of Medical Biochemistry, Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title | Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title_full | Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title_fullStr | Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title_full_unstemmed | Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title_short | Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title_sort | evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
title_unstemmed | Evaluation of neutrophil-lymphocyte and platelet-lymphocyte ratios as predictors of 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure |
url | http://dx.doi.org/10.2478/jomb-2018-0044 |