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Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis
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| Zeitschriftentitel: | The EuroBiotech Journal |
|---|---|
| Personen und Körperschaften: | , , , , |
| In: | The EuroBiotech Journal, 3, 2019, 4, S. 190-196 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Walter de Gruyter GmbH
|
| Schlagwörter: |
| author_facet |
Lim, Trisna Ouyang, Wei Martoni, Christopher John Balit, Nasri Prakash, Satya Lim, Trisna Ouyang, Wei Martoni, Christopher John Balit, Nasri Prakash, Satya |
|---|---|
| author |
Lim, Trisna Ouyang, Wei Martoni, Christopher John Balit, Nasri Prakash, Satya |
| spellingShingle |
Lim, Trisna Ouyang, Wei Martoni, Christopher John Balit, Nasri Prakash, Satya The EuroBiotech Journal Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis Genetics Molecular Biology Biomedical Engineering Molecular Medicine Food Science Biotechnology |
| author_sort |
lim, trisna |
| spelling |
Lim, Trisna Ouyang, Wei Martoni, Christopher John Balit, Nasri Prakash, Satya 2564-615X Walter de Gruyter GmbH Genetics Molecular Biology Biomedical Engineering Molecular Medicine Food Science Biotechnology http://dx.doi.org/10.2478/ebtj-2019-0023 <jats:title>Abstract</jats:title> <jats:p>Activated charcoal was microencapsulated with <jats:italic>Lactobacillus acidophilus</jats:italic> 314 previously adapted for urea uptake. The creatinine removal capacity of this combination microcapsule was evaluated in-vitro in media simulating the small intestine. Results show that microcapsules containing both activated charcoal and <jats:italic>L. acidophilus</jats:italic> 314 demonstrated potential for decreasing creatinine. Interestingly, when co-encapsulating both activated charcoal and <jats:italic>L. acidophilus</jats:italic> 314 a smaller decrease in creatinine was observed than when encapsulating them separately. However, co-encapsulated microcapsules were more stable in various parts of the gastrointestinal system and survived longer in storage. These results suggest the feasibility of using microcapsules containing activated charcoal and probiotic bacteria as oral adjuvants for creatinine removal and provides a theoretical model for the use of these microcapsules to remove any unwanted metabolite.</jats:p> Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and <i>in-vitro</i> analysis The EuroBiotech Journal |
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Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis |
| title_unstemmed |
Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis |
| title_full |
Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis |
| title_fullStr |
Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis |
| title_full_unstemmed |
Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis |
| title_short |
Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis |
| title_sort |
artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and <i>in-vitro</i> analysis |
| topic |
Genetics Molecular Biology Biomedical Engineering Molecular Medicine Food Science Biotechnology |
| url |
http://dx.doi.org/10.2478/ebtj-2019-0023 |
| publishDate |
2019 |
| physical |
190-196 |
| description |
<jats:title>Abstract</jats:title>
<jats:p>Activated charcoal was microencapsulated with <jats:italic>Lactobacillus acidophilus</jats:italic> 314 previously adapted for urea uptake. The creatinine removal capacity of this combination microcapsule was evaluated in-vitro in media simulating the small intestine. Results show that microcapsules containing both activated charcoal and <jats:italic>L. acidophilus</jats:italic> 314 demonstrated potential for decreasing creatinine. Interestingly, when co-encapsulating both activated charcoal and <jats:italic>L. acidophilus</jats:italic> 314 a smaller decrease in creatinine was observed than when encapsulating them separately. However, co-encapsulated microcapsules were more stable in various parts of the gastrointestinal system and survived longer in storage. These results suggest the feasibility of using microcapsules containing activated charcoal and probiotic bacteria as oral adjuvants for creatinine removal and provides a theoretical model for the use of these microcapsules to remove any unwanted metabolite.</jats:p> |
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| author | Lim, Trisna, Ouyang, Wei, Martoni, Christopher John, Balit, Nasri, Prakash, Satya |
| author_facet | Lim, Trisna, Ouyang, Wei, Martoni, Christopher John, Balit, Nasri, Prakash, Satya, Lim, Trisna, Ouyang, Wei, Martoni, Christopher John, Balit, Nasri, Prakash, Satya |
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| description | <jats:title>Abstract</jats:title> <jats:p>Activated charcoal was microencapsulated with <jats:italic>Lactobacillus acidophilus</jats:italic> 314 previously adapted for urea uptake. The creatinine removal capacity of this combination microcapsule was evaluated in-vitro in media simulating the small intestine. Results show that microcapsules containing both activated charcoal and <jats:italic>L. acidophilus</jats:italic> 314 demonstrated potential for decreasing creatinine. Interestingly, when co-encapsulating both activated charcoal and <jats:italic>L. acidophilus</jats:italic> 314 a smaller decrease in creatinine was observed than when encapsulating them separately. However, co-encapsulated microcapsules were more stable in various parts of the gastrointestinal system and survived longer in storage. These results suggest the feasibility of using microcapsules containing activated charcoal and probiotic bacteria as oral adjuvants for creatinine removal and provides a theoretical model for the use of these microcapsules to remove any unwanted metabolite.</jats:p> |
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| physical | 190-196 |
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| spelling | Lim, Trisna Ouyang, Wei Martoni, Christopher John Balit, Nasri Prakash, Satya 2564-615X Walter de Gruyter GmbH Genetics Molecular Biology Biomedical Engineering Molecular Medicine Food Science Biotechnology http://dx.doi.org/10.2478/ebtj-2019-0023 <jats:title>Abstract</jats:title> <jats:p>Activated charcoal was microencapsulated with <jats:italic>Lactobacillus acidophilus</jats:italic> 314 previously adapted for urea uptake. The creatinine removal capacity of this combination microcapsule was evaluated in-vitro in media simulating the small intestine. Results show that microcapsules containing both activated charcoal and <jats:italic>L. acidophilus</jats:italic> 314 demonstrated potential for decreasing creatinine. Interestingly, when co-encapsulating both activated charcoal and <jats:italic>L. acidophilus</jats:italic> 314 a smaller decrease in creatinine was observed than when encapsulating them separately. However, co-encapsulated microcapsules were more stable in various parts of the gastrointestinal system and survived longer in storage. These results suggest the feasibility of using microcapsules containing activated charcoal and probiotic bacteria as oral adjuvants for creatinine removal and provides a theoretical model for the use of these microcapsules to remove any unwanted metabolite.</jats:p> Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and <i>in-vitro</i> analysis The EuroBiotech Journal |
| spellingShingle | Lim, Trisna, Ouyang, Wei, Martoni, Christopher John, Balit, Nasri, Prakash, Satya, The EuroBiotech Journal, Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis, Genetics, Molecular Biology, Biomedical Engineering, Molecular Medicine, Food Science, Biotechnology |
| title | Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis |
| title_full | Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis |
| title_fullStr | Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis |
| title_full_unstemmed | Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis |
| title_short | Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis |
| title_sort | artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and <i>in-vitro</i> analysis |
| title_unstemmed | Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis |
| topic | Genetics, Molecular Biology, Biomedical Engineering, Molecular Medicine, Food Science, Biotechnology |
| url | http://dx.doi.org/10.2478/ebtj-2019-0023 |