Eintrag weiter verarbeiten
Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada
Gespeichert in:
| Zeitschriftentitel: | Clinical Journal of the American Society of Nephrology |
|---|---|
| Personen und Körperschaften: | , , , , , |
| In: | Clinical Journal of the American Society of Nephrology, 8, 2013, 2, S. 265-270 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Ovid Technologies (Wolters Kluwer Health)
|
| Schlagwörter: |
| author_facet |
Ellwood, Amanda D. Jassal, S. Vanita Suri, Rita S. Clark, William F. Na, Yingo Moist, Louise M. Ellwood, Amanda D. Jassal, S. Vanita Suri, Rita S. Clark, William F. Na, Yingo Moist, Louise M. |
|---|---|
| author |
Ellwood, Amanda D. Jassal, S. Vanita Suri, Rita S. Clark, William F. Na, Yingo Moist, Louise M. |
| spellingShingle |
Ellwood, Amanda D. Jassal, S. Vanita Suri, Rita S. Clark, William F. Na, Yingo Moist, Louise M. Clinical Journal of the American Society of Nephrology Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada Transplantation Nephrology Critical Care and Intensive Care Medicine Epidemiology |
| author_sort |
ellwood, amanda d. |
| spelling |
Ellwood, Amanda D. Jassal, S. Vanita Suri, Rita S. Clark, William F. Na, Yingo Moist, Louise M. 1555-9041 Ovid Technologies (Wolters Kluwer Health) Transplantation Nephrology Critical Care and Intensive Care Medicine Epidemiology http://dx.doi.org/10.2215/cjn.01000112 <jats:title>Summary</jats:title> <jats:sec> <jats:title>Background and objectives</jats:title> <jats:p>The number of elderly patients and those with higher estimated GFR (eGFR) initiating dialysis have recently increased. This study sought to determine rates of withdrawal from dialysis and variables associated with withdrawal.</jats:p> </jats:sec> <jats:sec> <jats:title>Design, setting, participants, & measurements</jats:title> <jats:p>Canadian Organ Replacement Registry data were used to examine withdrawal rate and identify variables associated with withdrawal among the total cohort, patients age < 75 years, and patients age ≥ 75 years, along with those with early (eGFR > 10.5 ml/min per 1.73 m<jats:sup>2</jats:sup>) and those with late (eGFR ≤ 10.5 ml/min per 1.73 m<jats:sup>2</jats:sup>) initiation of dialysis, using a Cox proportional hazard model in patients starting dialysis between 2001 and 2009, with follow-up to December 31, 2009.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>Median follow-up duration was 23.0 (interquartile range [IQR], 34.3) months. Rate of withdrawal per 100 patient-years doubled from 1.5 to 3.0, and withdrawal as cause of death increased from 7.9% to 19.5% between 2001 and 2009. Early initiation of dialysis was associated with increased withdrawal risk (hazard ratio, 1.17; 95% confidence interval, 1.06–1.30; <jats:italic toggle="yes">P</jats:italic>=0.002), as were older age, female sex, white race, and late referral to nephrologist. Patients age ≥ 75 years withdrew earlier after dialysis initiation (median, 15.9 [IQR, 27.9] months) compared to those age < 75 years (21.6 [IQR, 35.2] months). Early-start patients withdrew earlier (median, 15.6 [IQR, 28.5] months) compared with late-start patients (20.2 [IQR, 32.9] months).</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions</jats:title> <jats:p>In Canada, withdrawal from dialysis has increased significantly over recent years, especially among patients starting with higher eGFRs and in the elderly.</jats:p> </jats:sec> Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada Clinical Journal of the American Society of Nephrology |
| doi_str_mv |
10.2215/cjn.01000112 |
| facet_avail |
Online Free |
| finc_class_facet |
Medizin |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMjIxNS9jam4uMDEwMDAxMTI |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMjIxNS9jam4uMDEwMDAxMTI |
| institution |
DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-D161 DE-Zwi2 |
| imprint |
Ovid Technologies (Wolters Kluwer Health), 2013 |
| imprint_str_mv |
Ovid Technologies (Wolters Kluwer Health), 2013 |
| issn |
1555-9041 |
| issn_str_mv |
1555-9041 |
| language |
English |
| mega_collection |
Ovid Technologies (Wolters Kluwer Health) (CrossRef) |
| match_str |
ellwood2013earlydialysisinitiationandratesandtimingofwithdrawalfromdialysisincanada |
| publishDateSort |
2013 |
| publisher |
Ovid Technologies (Wolters Kluwer Health) |
| recordtype |
ai |
| record_format |
ai |
| series |
Clinical Journal of the American Society of Nephrology |
| source_id |
49 |
| title |
Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada |
| title_unstemmed |
Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada |
| title_full |
Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada |
| title_fullStr |
Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada |
| title_full_unstemmed |
Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada |
| title_short |
Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada |
| title_sort |
early dialysis initiation and rates and timing of withdrawal from dialysis in canada |
| topic |
Transplantation Nephrology Critical Care and Intensive Care Medicine Epidemiology |
| url |
http://dx.doi.org/10.2215/cjn.01000112 |
| publishDate |
2013 |
| physical |
265-270 |
| description |
<jats:title>Summary</jats:title>
<jats:sec>
<jats:title>Background and objectives</jats:title>
<jats:p>The number of elderly patients and those with higher estimated GFR (eGFR) initiating dialysis have recently increased. This study sought to determine rates of withdrawal from dialysis and variables associated with withdrawal.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Design, setting, participants, & measurements</jats:title>
<jats:p>Canadian Organ Replacement Registry data were used to examine withdrawal rate and identify variables associated with withdrawal among the total cohort, patients age < 75 years, and patients age ≥ 75 years, along with those with early (eGFR > 10.5 ml/min per 1.73 m<jats:sup>2</jats:sup>) and those with late (eGFR ≤ 10.5 ml/min per 1.73 m<jats:sup>2</jats:sup>) initiation of dialysis, using a Cox proportional hazard model in patients starting dialysis between 2001 and 2009, with follow-up to December 31, 2009.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Results</jats:title>
<jats:p>Median follow-up duration was 23.0 (interquartile range [IQR], 34.3) months. Rate of withdrawal per 100 patient-years doubled from 1.5 to 3.0, and withdrawal as cause of death increased from 7.9% to 19.5% between 2001 and 2009. Early initiation of dialysis was associated with increased withdrawal risk (hazard ratio, 1.17; 95% confidence interval, 1.06–1.30; <jats:italic toggle="yes">P</jats:italic>=0.002), as were older age, female sex, white race, and late referral to nephrologist. Patients age ≥ 75 years withdrew earlier after dialysis initiation (median, 15.9 [IQR, 27.9] months) compared to those age < 75 years (21.6 [IQR, 35.2] months). Early-start patients withdrew earlier (median, 15.6 [IQR, 28.5] months) compared with late-start patients (20.2 [IQR, 32.9] months).</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Conclusions</jats:title>
<jats:p>In Canada, withdrawal from dialysis has increased significantly over recent years, especially among patients starting with higher eGFRs and in the elderly.</jats:p>
</jats:sec> |
| container_issue |
2 |
| container_start_page |
265 |
| container_title |
Clinical Journal of the American Society of Nephrology |
| container_volume |
8 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792348202656071690 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T18:07:25Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Early+Dialysis+Initiation+and+Rates+and+Timing+of+Withdrawal+From+Dialysis+in+Canada&rft.date=2013-02-01&genre=article&issn=1555-9041&volume=8&issue=2&spage=265&epage=270&pages=265-270&jtitle=Clinical+Journal+of+the+American+Society+of+Nephrology&atitle=Early+Dialysis+Initiation+and+Rates+and+Timing+of+Withdrawal+From+Dialysis+in+Canada&aulast=Moist&aufirst=Louise+M.&rft_id=info%3Adoi%2F10.2215%2Fcjn.01000112&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792348202656071690 |
| author | Ellwood, Amanda D., Jassal, S. Vanita, Suri, Rita S., Clark, William F., Na, Yingo, Moist, Louise M. |
| author_facet | Ellwood, Amanda D., Jassal, S. Vanita, Suri, Rita S., Clark, William F., Na, Yingo, Moist, Louise M., Ellwood, Amanda D., Jassal, S. Vanita, Suri, Rita S., Clark, William F., Na, Yingo, Moist, Louise M. |
| author_sort | ellwood, amanda d. |
| container_issue | 2 |
| container_start_page | 265 |
| container_title | Clinical Journal of the American Society of Nephrology |
| container_volume | 8 |
| description | <jats:title>Summary</jats:title> <jats:sec> <jats:title>Background and objectives</jats:title> <jats:p>The number of elderly patients and those with higher estimated GFR (eGFR) initiating dialysis have recently increased. This study sought to determine rates of withdrawal from dialysis and variables associated with withdrawal.</jats:p> </jats:sec> <jats:sec> <jats:title>Design, setting, participants, & measurements</jats:title> <jats:p>Canadian Organ Replacement Registry data were used to examine withdrawal rate and identify variables associated with withdrawal among the total cohort, patients age < 75 years, and patients age ≥ 75 years, along with those with early (eGFR > 10.5 ml/min per 1.73 m<jats:sup>2</jats:sup>) and those with late (eGFR ≤ 10.5 ml/min per 1.73 m<jats:sup>2</jats:sup>) initiation of dialysis, using a Cox proportional hazard model in patients starting dialysis between 2001 and 2009, with follow-up to December 31, 2009.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>Median follow-up duration was 23.0 (interquartile range [IQR], 34.3) months. Rate of withdrawal per 100 patient-years doubled from 1.5 to 3.0, and withdrawal as cause of death increased from 7.9% to 19.5% between 2001 and 2009. Early initiation of dialysis was associated with increased withdrawal risk (hazard ratio, 1.17; 95% confidence interval, 1.06–1.30; <jats:italic toggle="yes">P</jats:italic>=0.002), as were older age, female sex, white race, and late referral to nephrologist. Patients age ≥ 75 years withdrew earlier after dialysis initiation (median, 15.9 [IQR, 27.9] months) compared to those age < 75 years (21.6 [IQR, 35.2] months). Early-start patients withdrew earlier (median, 15.6 [IQR, 28.5] months) compared with late-start patients (20.2 [IQR, 32.9] months).</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions</jats:title> <jats:p>In Canada, withdrawal from dialysis has increased significantly over recent years, especially among patients starting with higher eGFRs and in the elderly.</jats:p> </jats:sec> |
| doi_str_mv | 10.2215/cjn.01000112 |
| facet_avail | Online, Free |
| finc_class_facet | Medizin |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMjIxNS9jam4uMDEwMDAxMTI |
| imprint | Ovid Technologies (Wolters Kluwer Health), 2013 |
| imprint_str_mv | Ovid Technologies (Wolters Kluwer Health), 2013 |
| institution | DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Zwi2 |
| issn | 1555-9041 |
| issn_str_mv | 1555-9041 |
| language | English |
| last_indexed | 2024-03-01T18:07:25Z |
| match_str | ellwood2013earlydialysisinitiationandratesandtimingofwithdrawalfromdialysisincanada |
| mega_collection | Ovid Technologies (Wolters Kluwer Health) (CrossRef) |
| physical | 265-270 |
| publishDate | 2013 |
| publishDateSort | 2013 |
| publisher | Ovid Technologies (Wolters Kluwer Health) |
| record_format | ai |
| recordtype | ai |
| series | Clinical Journal of the American Society of Nephrology |
| source_id | 49 |
| spelling | Ellwood, Amanda D. Jassal, S. Vanita Suri, Rita S. Clark, William F. Na, Yingo Moist, Louise M. 1555-9041 Ovid Technologies (Wolters Kluwer Health) Transplantation Nephrology Critical Care and Intensive Care Medicine Epidemiology http://dx.doi.org/10.2215/cjn.01000112 <jats:title>Summary</jats:title> <jats:sec> <jats:title>Background and objectives</jats:title> <jats:p>The number of elderly patients and those with higher estimated GFR (eGFR) initiating dialysis have recently increased. This study sought to determine rates of withdrawal from dialysis and variables associated with withdrawal.</jats:p> </jats:sec> <jats:sec> <jats:title>Design, setting, participants, & measurements</jats:title> <jats:p>Canadian Organ Replacement Registry data were used to examine withdrawal rate and identify variables associated with withdrawal among the total cohort, patients age < 75 years, and patients age ≥ 75 years, along with those with early (eGFR > 10.5 ml/min per 1.73 m<jats:sup>2</jats:sup>) and those with late (eGFR ≤ 10.5 ml/min per 1.73 m<jats:sup>2</jats:sup>) initiation of dialysis, using a Cox proportional hazard model in patients starting dialysis between 2001 and 2009, with follow-up to December 31, 2009.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>Median follow-up duration was 23.0 (interquartile range [IQR], 34.3) months. Rate of withdrawal per 100 patient-years doubled from 1.5 to 3.0, and withdrawal as cause of death increased from 7.9% to 19.5% between 2001 and 2009. Early initiation of dialysis was associated with increased withdrawal risk (hazard ratio, 1.17; 95% confidence interval, 1.06–1.30; <jats:italic toggle="yes">P</jats:italic>=0.002), as were older age, female sex, white race, and late referral to nephrologist. Patients age ≥ 75 years withdrew earlier after dialysis initiation (median, 15.9 [IQR, 27.9] months) compared to those age < 75 years (21.6 [IQR, 35.2] months). Early-start patients withdrew earlier (median, 15.6 [IQR, 28.5] months) compared with late-start patients (20.2 [IQR, 32.9] months).</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions</jats:title> <jats:p>In Canada, withdrawal from dialysis has increased significantly over recent years, especially among patients starting with higher eGFRs and in the elderly.</jats:p> </jats:sec> Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada Clinical Journal of the American Society of Nephrology |
| spellingShingle | Ellwood, Amanda D., Jassal, S. Vanita, Suri, Rita S., Clark, William F., Na, Yingo, Moist, Louise M., Clinical Journal of the American Society of Nephrology, Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada, Transplantation, Nephrology, Critical Care and Intensive Care Medicine, Epidemiology |
| title | Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada |
| title_full | Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada |
| title_fullStr | Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada |
| title_full_unstemmed | Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada |
| title_short | Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada |
| title_sort | early dialysis initiation and rates and timing of withdrawal from dialysis in canada |
| title_unstemmed | Early Dialysis Initiation and Rates and Timing of Withdrawal From Dialysis in Canada |
| topic | Transplantation, Nephrology, Critical Care and Intensive Care Medicine, Epidemiology |
| url | http://dx.doi.org/10.2215/cjn.01000112 |