author_facet Tamaki, Yukimichi
Kataoka, Yu
Jang, In-Kee
Miyazaki, Takashi
Tamaki, Yukimichi
Kataoka, Yu
Jang, In-Kee
Miyazaki, Takashi
author Tamaki, Yukimichi
Kataoka, Yu
Jang, In-Kee
Miyazaki, Takashi
spellingShingle Tamaki, Yukimichi
Kataoka, Yu
Jang, In-Kee
Miyazaki, Takashi
The Open Materials Science Journal
Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
General Materials Science
author_sort tamaki, yukimichi
spelling Tamaki, Yukimichi Kataoka, Yu Jang, In-Kee Miyazaki, Takashi 1874-088X Bentham Science Publishers Ltd. General Materials Science http://dx.doi.org/10.2174/1874088x010040100113 <jats:p>A new strategy with bone tissue engineering by mesenchymal stem cell transplantation on titanium implant has been drawn attention. The surface scaffold properties of titanium surface play an important role in bone regenerative potential of cells. The surface topography and chemistry are postulated to be two major factors increasing the scaffold properties of titanium implants. This study aimed to evaluate the osteogenic gene expression of mesenchymal stem cells on titanium processed by wire-type electric discharge machining. Some amount of roughness and distinctive irregular features was observed on titanium processed by wire-type electric discharge machining. The thickness of suboxide layer was concomitantly grown during the processing. Since the thickness of oxide film and micro-topography allowed an improvement of mRNA expression of cells, titanium processed by wire-type electric discharge machining is a promising candidate for mesenchymal stem cell based functional restoration of implants. </jats:p> Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining The Open Materials Science Journal
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series The Open Materials Science Journal
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title Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
title_unstemmed Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
title_full Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
title_fullStr Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
title_full_unstemmed Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
title_short Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
title_sort bone regenerative potential of mesenchymal stem cells on a micro- structured titanium processed by wire-type electric discharge machining
topic General Materials Science
url http://dx.doi.org/10.2174/1874088x010040100113
publishDate 2010
physical 113-116
description <jats:p>A new strategy with bone tissue engineering by mesenchymal stem cell transplantation on titanium implant has been drawn attention. The surface scaffold properties of titanium surface play an important role in bone regenerative potential of cells. The surface topography and chemistry are postulated to be two major factors increasing the scaffold properties of titanium implants. This study aimed to evaluate the osteogenic gene expression of mesenchymal stem cells on titanium processed by wire-type electric discharge machining. Some amount of roughness and distinctive irregular features was observed on titanium processed by wire-type electric discharge machining. The thickness of suboxide layer was concomitantly grown during the processing. Since the thickness of oxide film and micro-topography allowed an improvement of mRNA expression of cells, titanium processed by wire-type electric discharge machining is a promising candidate for mesenchymal stem cell based functional restoration of implants. </jats:p>
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author Tamaki, Yukimichi, Kataoka, Yu, Jang, In-Kee, Miyazaki, Takashi
author_facet Tamaki, Yukimichi, Kataoka, Yu, Jang, In-Kee, Miyazaki, Takashi, Tamaki, Yukimichi, Kataoka, Yu, Jang, In-Kee, Miyazaki, Takashi
author_sort tamaki, yukimichi
container_issue 1
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container_title The Open Materials Science Journal
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description <jats:p>A new strategy with bone tissue engineering by mesenchymal stem cell transplantation on titanium implant has been drawn attention. The surface scaffold properties of titanium surface play an important role in bone regenerative potential of cells. The surface topography and chemistry are postulated to be two major factors increasing the scaffold properties of titanium implants. This study aimed to evaluate the osteogenic gene expression of mesenchymal stem cells on titanium processed by wire-type electric discharge machining. Some amount of roughness and distinctive irregular features was observed on titanium processed by wire-type electric discharge machining. The thickness of suboxide layer was concomitantly grown during the processing. Since the thickness of oxide film and micro-topography allowed an improvement of mRNA expression of cells, titanium processed by wire-type electric discharge machining is a promising candidate for mesenchymal stem cell based functional restoration of implants. </jats:p>
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spelling Tamaki, Yukimichi Kataoka, Yu Jang, In-Kee Miyazaki, Takashi 1874-088X Bentham Science Publishers Ltd. General Materials Science http://dx.doi.org/10.2174/1874088x010040100113 <jats:p>A new strategy with bone tissue engineering by mesenchymal stem cell transplantation on titanium implant has been drawn attention. The surface scaffold properties of titanium surface play an important role in bone regenerative potential of cells. The surface topography and chemistry are postulated to be two major factors increasing the scaffold properties of titanium implants. This study aimed to evaluate the osteogenic gene expression of mesenchymal stem cells on titanium processed by wire-type electric discharge machining. Some amount of roughness and distinctive irregular features was observed on titanium processed by wire-type electric discharge machining. The thickness of suboxide layer was concomitantly grown during the processing. Since the thickness of oxide film and micro-topography allowed an improvement of mRNA expression of cells, titanium processed by wire-type electric discharge machining is a promising candidate for mesenchymal stem cell based functional restoration of implants. </jats:p> Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining The Open Materials Science Journal
spellingShingle Tamaki, Yukimichi, Kataoka, Yu, Jang, In-Kee, Miyazaki, Takashi, The Open Materials Science Journal, Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining, General Materials Science
title Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
title_full Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
title_fullStr Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
title_full_unstemmed Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
title_short Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
title_sort bone regenerative potential of mesenchymal stem cells on a micro- structured titanium processed by wire-type electric discharge machining
title_unstemmed Bone Regenerative Potential of Mesenchymal Stem Cells on a Micro- Structured Titanium Processed by Wire-Type Electric Discharge Machining
topic General Materials Science
url http://dx.doi.org/10.2174/1874088x010040100113