author_facet Mann, T
Mann, T
author Mann, T
spellingShingle Mann, T
South African Journal of Sports Medicine
Sporting myths: the REAL role of lactate during exercise
Applied Mathematics
General Mathematics
author_sort mann, t
spelling Mann, T 2078-516X 1015-5163 Academy of Science of South Africa Applied Mathematics General Mathematics http://dx.doi.org/10.17159/2078-516x/2007/v19i5a655 <jats:p>Background. Lactate or, as it was customarily known, ‘lactic acid’ was one of the first molecules to attract the attention of early exercise scientists, mainly because blood lactate concentration could be measured and was shown to increase with increasing exercise intensity. This connection resulted in lactate being associated with numerous other events associated with high-intensity exercise including muscle cramps, fatigue, acidosis and post-exercise muscle soreness. Nobel prize-winning research by AV Hill and Otto Meyerhof provided a rational explanation linking lactate to anaerobiosis and acidosis, which resulted in this relationship being widely accepted as fact. It was only following isotopic tracer studies of George Brooks and others that the true role of lactate during rest and exercise was revealed. Conclusions. Lactate is now acknowledged as an important intermediate of carbohydrate metabolism, taken up from the blood by tissues such as skeletal and cardiac muscle as a substrate for oxidation. Furthermore, lactate formation consumes a proton, thereby buffering against muscle acidosis. For this reason, lactate production forms an essential aid to endurance performance rather than a hindrance.</jats:p> Sporting myths: the REAL role of lactate during exercise South African Journal of Sports Medicine
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title Sporting myths: the REAL role of lactate during exercise
title_unstemmed Sporting myths: the REAL role of lactate during exercise
title_full Sporting myths: the REAL role of lactate during exercise
title_fullStr Sporting myths: the REAL role of lactate during exercise
title_full_unstemmed Sporting myths: the REAL role of lactate during exercise
title_short Sporting myths: the REAL role of lactate during exercise
title_sort sporting myths: the real role of lactate during exercise
topic Applied Mathematics
General Mathematics
url http://dx.doi.org/10.17159/2078-516x/2007/v19i5a655
publishDate 2007
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description <jats:p>Background. Lactate or, as it was customarily known, ‘lactic acid’ was one of the first molecules to attract the attention of early exercise scientists, mainly because blood lactate concentration could be measured and was shown to increase with increasing exercise intensity. This connection resulted in lactate being associated with numerous other events associated with high-intensity exercise including muscle cramps, fatigue, acidosis and post-exercise muscle soreness. Nobel prize-winning research by AV Hill and Otto Meyerhof provided a rational explanation linking lactate to anaerobiosis and acidosis, which resulted in this relationship being widely accepted as fact. It was only following isotopic tracer studies of George Brooks and others that the true role of lactate during rest and exercise was revealed. Conclusions. Lactate is now acknowledged as an important intermediate of carbohydrate metabolism, taken up from the blood by tissues such as skeletal and cardiac muscle as a substrate for oxidation. Furthermore, lactate formation consumes a proton, thereby buffering against muscle acidosis. For this reason, lactate production forms an essential aid to endurance performance rather than a hindrance.</jats:p>
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description <jats:p>Background. Lactate or, as it was customarily known, ‘lactic acid’ was one of the first molecules to attract the attention of early exercise scientists, mainly because blood lactate concentration could be measured and was shown to increase with increasing exercise intensity. This connection resulted in lactate being associated with numerous other events associated with high-intensity exercise including muscle cramps, fatigue, acidosis and post-exercise muscle soreness. Nobel prize-winning research by AV Hill and Otto Meyerhof provided a rational explanation linking lactate to anaerobiosis and acidosis, which resulted in this relationship being widely accepted as fact. It was only following isotopic tracer studies of George Brooks and others that the true role of lactate during rest and exercise was revealed. Conclusions. Lactate is now acknowledged as an important intermediate of carbohydrate metabolism, taken up from the blood by tissues such as skeletal and cardiac muscle as a substrate for oxidation. Furthermore, lactate formation consumes a proton, thereby buffering against muscle acidosis. For this reason, lactate production forms an essential aid to endurance performance rather than a hindrance.</jats:p>
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spelling Mann, T 2078-516X 1015-5163 Academy of Science of South Africa Applied Mathematics General Mathematics http://dx.doi.org/10.17159/2078-516x/2007/v19i5a655 <jats:p>Background. Lactate or, as it was customarily known, ‘lactic acid’ was one of the first molecules to attract the attention of early exercise scientists, mainly because blood lactate concentration could be measured and was shown to increase with increasing exercise intensity. This connection resulted in lactate being associated with numerous other events associated with high-intensity exercise including muscle cramps, fatigue, acidosis and post-exercise muscle soreness. Nobel prize-winning research by AV Hill and Otto Meyerhof provided a rational explanation linking lactate to anaerobiosis and acidosis, which resulted in this relationship being widely accepted as fact. It was only following isotopic tracer studies of George Brooks and others that the true role of lactate during rest and exercise was revealed. Conclusions. Lactate is now acknowledged as an important intermediate of carbohydrate metabolism, taken up from the blood by tissues such as skeletal and cardiac muscle as a substrate for oxidation. Furthermore, lactate formation consumes a proton, thereby buffering against muscle acidosis. For this reason, lactate production forms an essential aid to endurance performance rather than a hindrance.</jats:p> Sporting myths: the REAL role of lactate during exercise South African Journal of Sports Medicine
spellingShingle Mann, T, South African Journal of Sports Medicine, Sporting myths: the REAL role of lactate during exercise, Applied Mathematics, General Mathematics
title Sporting myths: the REAL role of lactate during exercise
title_full Sporting myths: the REAL role of lactate during exercise
title_fullStr Sporting myths: the REAL role of lactate during exercise
title_full_unstemmed Sporting myths: the REAL role of lactate during exercise
title_short Sporting myths: the REAL role of lactate during exercise
title_sort sporting myths: the real role of lactate during exercise
title_unstemmed Sporting myths: the REAL role of lactate during exercise
topic Applied Mathematics, General Mathematics
url http://dx.doi.org/10.17159/2078-516x/2007/v19i5a655