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Risk Factors For Development Of Acute Necrotizing Pancreatitis
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| Zeitschriftentitel: | Serbian Journal of Experimental and Clinical Research |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , , , , , , , , |
| In: | Serbian Journal of Experimental and Clinical Research, 16, 2015, 2, S. 121-127 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Walter de Gruyter GmbH
|
| Schlagwörter: |
| author_facet |
Stojanovic, Bojan Spasic, Marko Radosavljevic, Ivan Canovic, Dragan Radovanovic, Dragce Praznik, Ivan Prodanovic, Nikola Milojevic, Andjela Jelic, Ivana Babic, Zivan Artinovic, Viktorija Grubor, Iva Nikolic, Ljiljana Vucicevic, Ksenija Miljkovic, Jelena Divjak, Ana Stefanovic, Srdjan Jankovic, Slobodan Stojanovic, Bojan Spasic, Marko Radosavljevic, Ivan Canovic, Dragan Radovanovic, Dragce Praznik, Ivan Prodanovic, Nikola Milojevic, Andjela Jelic, Ivana Babic, Zivan Artinovic, Viktorija Grubor, Iva Nikolic, Ljiljana Vucicevic, Ksenija Miljkovic, Jelena Divjak, Ana Stefanovic, Srdjan Jankovic, Slobodan |
|---|---|
| author |
Stojanovic, Bojan Spasic, Marko Radosavljevic, Ivan Canovic, Dragan Radovanovic, Dragce Praznik, Ivan Prodanovic, Nikola Milojevic, Andjela Jelic, Ivana Babic, Zivan Artinovic, Viktorija Grubor, Iva Nikolic, Ljiljana Vucicevic, Ksenija Miljkovic, Jelena Divjak, Ana Stefanovic, Srdjan Jankovic, Slobodan |
| spellingShingle |
Stojanovic, Bojan Spasic, Marko Radosavljevic, Ivan Canovic, Dragan Radovanovic, Dragce Praznik, Ivan Prodanovic, Nikola Milojevic, Andjela Jelic, Ivana Babic, Zivan Artinovic, Viktorija Grubor, Iva Nikolic, Ljiljana Vucicevic, Ksenija Miljkovic, Jelena Divjak, Ana Stefanovic, Srdjan Jankovic, Slobodan Serbian Journal of Experimental and Clinical Research Risk Factors For Development Of Acute Necrotizing Pancreatitis General Medicine |
| author_sort |
stojanovic, bojan |
| spelling |
Stojanovic, Bojan Spasic, Marko Radosavljevic, Ivan Canovic, Dragan Radovanovic, Dragce Praznik, Ivan Prodanovic, Nikola Milojevic, Andjela Jelic, Ivana Babic, Zivan Artinovic, Viktorija Grubor, Iva Nikolic, Ljiljana Vucicevic, Ksenija Miljkovic, Jelena Divjak, Ana Stefanovic, Srdjan Jankovic, Slobodan 2335-075X 1820-8665 Walter de Gruyter GmbH General Medicine http://dx.doi.org/10.1515/sjecr-2015-0016 <jats:title>Abstract</jats:title> <jats:p>Acute necrotizing pancreatitis (ANP) is a severe form of acute pancreatitis that is associated with high morbidity and mortality. Thus, an adequate initial treatment of patients who present with acute pancreatitis (AP) based on correct interpretation of early detected laboratory and clinical abnormalities may have a significant positive impact on the disease course.</jats:p> <jats:p>The aim of the study was to determine patient- and initial treatment-related risk factors for the development of acute necrotizing pancreatitis.</jats:p> <jats:p>For the purpose of this study a case-control design was chosen, including adult patients treated for AP in the surgical Intensive Care Unit (sICU) of Clinical Center of Kragujevac, from January 2006 to January 2011. The cases (n=63) were patients who developed ANP, while the controls (n=63) were patients with AP without the presence of pancreatic necrosis. The controls were randomly selected from a study sample after matching with the cases by age and sex.</jats:p> <jats:p>Significant association with the development of ANP was found for the presence of comorbidity (adjusted OR 6.614 95%CI 1.185-36.963), and the use of somatostatin (adjusted OR 7.460, 95%CI 1.162-47.833) and furosemide (adjusted OR 2710.57, 95%CI 1.996-56.035) started immediately upon admission to the sICU.</jats:p> <jats:p>This study suggests that comorbidities, particularly the presence of serious cardio-vascular disease, can increase the risk for development of acute necrotizing pancreatitis. The probability for the development of ANP could be reduced by the avoidance of the initial use of loop diuretics and somatostatin.</jats:p> Risk Factors For Development Of Acute Necrotizing Pancreatitis Serbian Journal of Experimental and Clinical Research |
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Serbian Journal of Experimental and Clinical Research |
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Risk Factors For Development Of Acute Necrotizing Pancreatitis |
| title_unstemmed |
Risk Factors For Development Of Acute Necrotizing Pancreatitis |
| title_full |
Risk Factors For Development Of Acute Necrotizing Pancreatitis |
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Risk Factors For Development Of Acute Necrotizing Pancreatitis |
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Risk Factors For Development Of Acute Necrotizing Pancreatitis |
| title_short |
Risk Factors For Development Of Acute Necrotizing Pancreatitis |
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risk factors for development of acute necrotizing pancreatitis |
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General Medicine |
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http://dx.doi.org/10.1515/sjecr-2015-0016 |
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2015 |
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121-127 |
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<jats:title>Abstract</jats:title>
<jats:p>Acute necrotizing pancreatitis (ANP) is a severe form of acute pancreatitis that is associated with high morbidity and mortality. Thus, an adequate initial treatment of patients who present with acute pancreatitis (AP) based on correct interpretation of early detected laboratory and clinical abnormalities may have a significant positive impact on the disease course.</jats:p>
<jats:p>The aim of the study was to determine patient- and initial treatment-related risk factors for the development of acute necrotizing pancreatitis.</jats:p>
<jats:p>For the purpose of this study a case-control design was chosen, including adult patients treated for AP in the surgical Intensive Care Unit (sICU) of Clinical Center of Kragujevac, from January 2006 to January 2011. The cases (n=63) were patients who developed ANP, while the controls (n=63) were patients with AP without the presence of pancreatic necrosis. The controls were randomly selected from a study sample after matching with the cases by age and sex.</jats:p>
<jats:p>Significant association with the development of ANP was found for the presence of comorbidity (adjusted OR 6.614 95%CI 1.185-36.963), and the use of somatostatin (adjusted OR 7.460, 95%CI 1.162-47.833) and furosemide (adjusted OR 2710.57, 95%CI 1.996-56.035) started immediately upon admission to the sICU.</jats:p>
<jats:p>This study suggests that comorbidities, particularly the presence of serious cardio-vascular disease, can increase the risk for development of acute necrotizing pancreatitis. The probability for the development of ANP could be reduced by the avoidance of the initial use of loop diuretics and somatostatin.</jats:p> |
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| description | <jats:title>Abstract</jats:title> <jats:p>Acute necrotizing pancreatitis (ANP) is a severe form of acute pancreatitis that is associated with high morbidity and mortality. Thus, an adequate initial treatment of patients who present with acute pancreatitis (AP) based on correct interpretation of early detected laboratory and clinical abnormalities may have a significant positive impact on the disease course.</jats:p> <jats:p>The aim of the study was to determine patient- and initial treatment-related risk factors for the development of acute necrotizing pancreatitis.</jats:p> <jats:p>For the purpose of this study a case-control design was chosen, including adult patients treated for AP in the surgical Intensive Care Unit (sICU) of Clinical Center of Kragujevac, from January 2006 to January 2011. The cases (n=63) were patients who developed ANP, while the controls (n=63) were patients with AP without the presence of pancreatic necrosis. The controls were randomly selected from a study sample after matching with the cases by age and sex.</jats:p> <jats:p>Significant association with the development of ANP was found for the presence of comorbidity (adjusted OR 6.614 95%CI 1.185-36.963), and the use of somatostatin (adjusted OR 7.460, 95%CI 1.162-47.833) and furosemide (adjusted OR 2710.57, 95%CI 1.996-56.035) started immediately upon admission to the sICU.</jats:p> <jats:p>This study suggests that comorbidities, particularly the presence of serious cardio-vascular disease, can increase the risk for development of acute necrotizing pancreatitis. The probability for the development of ANP could be reduced by the avoidance of the initial use of loop diuretics and somatostatin.</jats:p> |
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| institution | DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229 |
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| spelling | Stojanovic, Bojan Spasic, Marko Radosavljevic, Ivan Canovic, Dragan Radovanovic, Dragce Praznik, Ivan Prodanovic, Nikola Milojevic, Andjela Jelic, Ivana Babic, Zivan Artinovic, Viktorija Grubor, Iva Nikolic, Ljiljana Vucicevic, Ksenija Miljkovic, Jelena Divjak, Ana Stefanovic, Srdjan Jankovic, Slobodan 2335-075X 1820-8665 Walter de Gruyter GmbH General Medicine http://dx.doi.org/10.1515/sjecr-2015-0016 <jats:title>Abstract</jats:title> <jats:p>Acute necrotizing pancreatitis (ANP) is a severe form of acute pancreatitis that is associated with high morbidity and mortality. Thus, an adequate initial treatment of patients who present with acute pancreatitis (AP) based on correct interpretation of early detected laboratory and clinical abnormalities may have a significant positive impact on the disease course.</jats:p> <jats:p>The aim of the study was to determine patient- and initial treatment-related risk factors for the development of acute necrotizing pancreatitis.</jats:p> <jats:p>For the purpose of this study a case-control design was chosen, including adult patients treated for AP in the surgical Intensive Care Unit (sICU) of Clinical Center of Kragujevac, from January 2006 to January 2011. The cases (n=63) were patients who developed ANP, while the controls (n=63) were patients with AP without the presence of pancreatic necrosis. The controls were randomly selected from a study sample after matching with the cases by age and sex.</jats:p> <jats:p>Significant association with the development of ANP was found for the presence of comorbidity (adjusted OR 6.614 95%CI 1.185-36.963), and the use of somatostatin (adjusted OR 7.460, 95%CI 1.162-47.833) and furosemide (adjusted OR 2710.57, 95%CI 1.996-56.035) started immediately upon admission to the sICU.</jats:p> <jats:p>This study suggests that comorbidities, particularly the presence of serious cardio-vascular disease, can increase the risk for development of acute necrotizing pancreatitis. The probability for the development of ANP could be reduced by the avoidance of the initial use of loop diuretics and somatostatin.</jats:p> Risk Factors For Development Of Acute Necrotizing Pancreatitis Serbian Journal of Experimental and Clinical Research |
| spellingShingle | Stojanovic, Bojan, Spasic, Marko, Radosavljevic, Ivan, Canovic, Dragan, Radovanovic, Dragce, Praznik, Ivan, Prodanovic, Nikola, Milojevic, Andjela, Jelic, Ivana, Babic, Zivan, Artinovic, Viktorija, Grubor, Iva, Nikolic, Ljiljana, Vucicevic, Ksenija, Miljkovic, Jelena, Divjak, Ana, Stefanovic, Srdjan, Jankovic, Slobodan, Serbian Journal of Experimental and Clinical Research, Risk Factors For Development Of Acute Necrotizing Pancreatitis, General Medicine |
| title | Risk Factors For Development Of Acute Necrotizing Pancreatitis |
| title_full | Risk Factors For Development Of Acute Necrotizing Pancreatitis |
| title_fullStr | Risk Factors For Development Of Acute Necrotizing Pancreatitis |
| title_full_unstemmed | Risk Factors For Development Of Acute Necrotizing Pancreatitis |
| title_short | Risk Factors For Development Of Acute Necrotizing Pancreatitis |
| title_sort | risk factors for development of acute necrotizing pancreatitis |
| title_unstemmed | Risk Factors For Development Of Acute Necrotizing Pancreatitis |
| topic | General Medicine |
| url | http://dx.doi.org/10.1515/sjecr-2015-0016 |