author_facet Cervellin, Gianfranco
Salvagno, Gianluca
Bonfanti, Laura
Bonelli, Patrizia
Guidi, Gian Cesare
Lippi, Giuseppe
Cervellin, Gianfranco
Salvagno, Gianluca
Bonfanti, Laura
Bonelli, Patrizia
Guidi, Gian Cesare
Lippi, Giuseppe
author Cervellin, Gianfranco
Salvagno, Gianluca
Bonfanti, Laura
Bonelli, Patrizia
Guidi, Gian Cesare
Lippi, Giuseppe
spellingShingle Cervellin, Gianfranco
Salvagno, Gianluca
Bonfanti, Laura
Bonelli, Patrizia
Guidi, Gian Cesare
Lippi, Giuseppe
Journal of Medical Biochemistry
Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
author_sort cervellin, gianfranco
spelling Cervellin, Gianfranco Salvagno, Gianluca Bonfanti, Laura Bonelli, Patrizia Guidi, Gian Cesare Lippi, Giuseppe 1452-8266 Centre for Evaluation in Education and Science (CEON/CEES) http://dx.doi.org/10.1515/jomb-2015-0003 <jats:title>Summary</jats:title><jats:p><jats:bold>Background:</jats:bold>Hyponatremia and vitamin D deficiency are frequent disorders, and both have been associated with gait disturbances, falls and fractures. The aim of this study was to evaluate the existence of an association between serum sodium and vitamin D serum levels.</jats:p><jats:p><jats:bold>Methods:</jats:bold>We performed a retrospective investigation to establish whether hyponatremia and vitamin D deficiency may be associated in a general population of unselected outpatients. An electronic search was performed in the laboratory information systems of the Hospital of Verona and the Hospital of Parma (Italy), to retrieve combined results for total vitamin D and sodium obtained in all outpatients referred for health check-up in the year 2013.</jats:p><jats:p><jats:bold>Results:</jats:bold>Combined results of vitamin D and sodium could be retrieved for 5097 outpatients (3859 females and 1238 males; mean age 64±17 years). Vitamin D deficient subjects displayed significantly lower levels of serum sodium (140 versus 141 mmol/L; p&lt;0.001), along with a significantly higher rate of hyponatremia (6.3% versus 5.1%; p=0.037). Accordingly, hyponatremic subjects had significantly lower levels of serum vitamin D (55 versus 60 nmol/L; p=0.015), along with a significantly higher rate of vitamin D deficiency (41.8% versus 36.1%; p=0.030). A highly significant correlation was found between sodium and total vitamin D after adjustment for age and gender (p&lt;0.001).</jats:p><jats:p><jats:bold>Conclusions:</jats:bold>The results of this study demonstrate for the first time the existence of a significant correlation between the serum levels of sodium and total vitamin D in a general population of unselected outpatients.</jats:p> Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults Journal of Medical Biochemistry
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title Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
title_unstemmed Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
title_full Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
title_fullStr Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
title_full_unstemmed Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
title_short Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
title_sort association of hyponatremia and hypovitaminosis d in ambulatory adults
url http://dx.doi.org/10.1515/jomb-2015-0003
publishDate 2015
physical 450-454
description <jats:title>Summary</jats:title><jats:p><jats:bold>Background:</jats:bold>Hyponatremia and vitamin D deficiency are frequent disorders, and both have been associated with gait disturbances, falls and fractures. The aim of this study was to evaluate the existence of an association between serum sodium and vitamin D serum levels.</jats:p><jats:p><jats:bold>Methods:</jats:bold>We performed a retrospective investigation to establish whether hyponatremia and vitamin D deficiency may be associated in a general population of unselected outpatients. An electronic search was performed in the laboratory information systems of the Hospital of Verona and the Hospital of Parma (Italy), to retrieve combined results for total vitamin D and sodium obtained in all outpatients referred for health check-up in the year 2013.</jats:p><jats:p><jats:bold>Results:</jats:bold>Combined results of vitamin D and sodium could be retrieved for 5097 outpatients (3859 females and 1238 males; mean age 64±17 years). Vitamin D deficient subjects displayed significantly lower levels of serum sodium (140 versus 141 mmol/L; p&lt;0.001), along with a significantly higher rate of hyponatremia (6.3% versus 5.1%; p=0.037). Accordingly, hyponatremic subjects had significantly lower levels of serum vitamin D (55 versus 60 nmol/L; p=0.015), along with a significantly higher rate of vitamin D deficiency (41.8% versus 36.1%; p=0.030). A highly significant correlation was found between sodium and total vitamin D after adjustment for age and gender (p&lt;0.001).</jats:p><jats:p><jats:bold>Conclusions:</jats:bold>The results of this study demonstrate for the first time the existence of a significant correlation between the serum levels of sodium and total vitamin D in a general population of unselected outpatients.</jats:p>
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author Cervellin, Gianfranco, Salvagno, Gianluca, Bonfanti, Laura, Bonelli, Patrizia, Guidi, Gian Cesare, Lippi, Giuseppe
author_facet Cervellin, Gianfranco, Salvagno, Gianluca, Bonfanti, Laura, Bonelli, Patrizia, Guidi, Gian Cesare, Lippi, Giuseppe, Cervellin, Gianfranco, Salvagno, Gianluca, Bonfanti, Laura, Bonelli, Patrizia, Guidi, Gian Cesare, Lippi, Giuseppe
author_sort cervellin, gianfranco
container_issue 4
container_start_page 450
container_title Journal of Medical Biochemistry
container_volume 34
description <jats:title>Summary</jats:title><jats:p><jats:bold>Background:</jats:bold>Hyponatremia and vitamin D deficiency are frequent disorders, and both have been associated with gait disturbances, falls and fractures. The aim of this study was to evaluate the existence of an association between serum sodium and vitamin D serum levels.</jats:p><jats:p><jats:bold>Methods:</jats:bold>We performed a retrospective investigation to establish whether hyponatremia and vitamin D deficiency may be associated in a general population of unselected outpatients. An electronic search was performed in the laboratory information systems of the Hospital of Verona and the Hospital of Parma (Italy), to retrieve combined results for total vitamin D and sodium obtained in all outpatients referred for health check-up in the year 2013.</jats:p><jats:p><jats:bold>Results:</jats:bold>Combined results of vitamin D and sodium could be retrieved for 5097 outpatients (3859 females and 1238 males; mean age 64±17 years). Vitamin D deficient subjects displayed significantly lower levels of serum sodium (140 versus 141 mmol/L; p&lt;0.001), along with a significantly higher rate of hyponatremia (6.3% versus 5.1%; p=0.037). Accordingly, hyponatremic subjects had significantly lower levels of serum vitamin D (55 versus 60 nmol/L; p=0.015), along with a significantly higher rate of vitamin D deficiency (41.8% versus 36.1%; p=0.030). A highly significant correlation was found between sodium and total vitamin D after adjustment for age and gender (p&lt;0.001).</jats:p><jats:p><jats:bold>Conclusions:</jats:bold>The results of this study demonstrate for the first time the existence of a significant correlation between the serum levels of sodium and total vitamin D in a general population of unselected outpatients.</jats:p>
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spelling Cervellin, Gianfranco Salvagno, Gianluca Bonfanti, Laura Bonelli, Patrizia Guidi, Gian Cesare Lippi, Giuseppe 1452-8266 Centre for Evaluation in Education and Science (CEON/CEES) http://dx.doi.org/10.1515/jomb-2015-0003 <jats:title>Summary</jats:title><jats:p><jats:bold>Background:</jats:bold>Hyponatremia and vitamin D deficiency are frequent disorders, and both have been associated with gait disturbances, falls and fractures. The aim of this study was to evaluate the existence of an association between serum sodium and vitamin D serum levels.</jats:p><jats:p><jats:bold>Methods:</jats:bold>We performed a retrospective investigation to establish whether hyponatremia and vitamin D deficiency may be associated in a general population of unselected outpatients. An electronic search was performed in the laboratory information systems of the Hospital of Verona and the Hospital of Parma (Italy), to retrieve combined results for total vitamin D and sodium obtained in all outpatients referred for health check-up in the year 2013.</jats:p><jats:p><jats:bold>Results:</jats:bold>Combined results of vitamin D and sodium could be retrieved for 5097 outpatients (3859 females and 1238 males; mean age 64±17 years). Vitamin D deficient subjects displayed significantly lower levels of serum sodium (140 versus 141 mmol/L; p&lt;0.001), along with a significantly higher rate of hyponatremia (6.3% versus 5.1%; p=0.037). Accordingly, hyponatremic subjects had significantly lower levels of serum vitamin D (55 versus 60 nmol/L; p=0.015), along with a significantly higher rate of vitamin D deficiency (41.8% versus 36.1%; p=0.030). A highly significant correlation was found between sodium and total vitamin D after adjustment for age and gender (p&lt;0.001).</jats:p><jats:p><jats:bold>Conclusions:</jats:bold>The results of this study demonstrate for the first time the existence of a significant correlation between the serum levels of sodium and total vitamin D in a general population of unselected outpatients.</jats:p> Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults Journal of Medical Biochemistry
spellingShingle Cervellin, Gianfranco, Salvagno, Gianluca, Bonfanti, Laura, Bonelli, Patrizia, Guidi, Gian Cesare, Lippi, Giuseppe, Journal of Medical Biochemistry, Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
title Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
title_full Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
title_fullStr Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
title_full_unstemmed Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
title_short Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
title_sort association of hyponatremia and hypovitaminosis d in ambulatory adults
title_unstemmed Association Of Hyponatremia And Hypovitaminosis D In Ambulatory Adults
url http://dx.doi.org/10.1515/jomb-2015-0003