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Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies
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| Zeitschriftentitel: | Cadernos de Saúde Pública |
|---|---|
| Personen und Körperschaften: | , , , , |
| In: | Cadernos de Saúde Pública, 29, 2013, 7, S. 1291-1300 |
| Format: | E-Article |
| Sprache: | Unbestimmt |
| veröffentlicht: |
FapUNIFESP (SciELO)
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| author_facet |
Ramos Jr., Alberto Novaes Matida, Luiza Harunari Alencar, Carlos Henrique Hearst, Norman Heukelbach, Jorg Ramos Jr., Alberto Novaes Matida, Luiza Harunari Alencar, Carlos Henrique Hearst, Norman Heukelbach, Jorg |
|---|---|
| author |
Ramos Jr., Alberto Novaes Matida, Luiza Harunari Alencar, Carlos Henrique Hearst, Norman Heukelbach, Jorg |
| spellingShingle |
Ramos Jr., Alberto Novaes Matida, Luiza Harunari Alencar, Carlos Henrique Hearst, Norman Heukelbach, Jorg Cadernos de Saúde Pública Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies Public Health, Environmental and Occupational Health |
| author_sort |
ramos jr., alberto novaes |
| spelling |
Ramos Jr., Alberto Novaes Matida, Luiza Harunari Alencar, Carlos Henrique Hearst, Norman Heukelbach, Jorg 0102-311X FapUNIFESP (SciELO) Public Health, Environmental and Occupational Health http://dx.doi.org/10.1590/s0102-311x2013000700004 <jats:p>This study analyzed data from two consecutive retrospective cohort samples (1983 to 1998 and 1999 to 2002) of Brazilian children with AIDS (N = 1,758) through mother-to-child-transmission. Late-stage diagnosis (CDC category C) was investigated in relation to the following variables: year of birth, year of HIV diagnosis, and time periods related to changes in government treatment guidelines. Late-stage diagnosis occurred in 731 (41.6%) of cases and was more prevalent in infants under 12 months of age. The rate of late-stage diagnosis decreased from 48% to 36% between the two periods studied. We also observed a reduction in the proportion of late-stage diagnoses and the time lapse between HIV diagnosis and ART initiation. A significant association was found between timely diagnosis and having been born in recent years (OR = 0.62; p = 0.009) and year of HIV diagnosis (OR = 0.72; p = 0.002/OR = 0.62; p < 0.001). Infants under the age of 12 months were more likely to be diagnosed at a late stage than older children (OR = 1.70; p = 0.004). Despite advances, there is a need to improve the effectiveness of policies and programs focused on improving early diagnosis and management of HIV/AIDS.</jats:p> Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies Cadernos de Saúde Pública |
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| title |
Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies |
| title_unstemmed |
Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies |
| title_full |
Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies |
| title_fullStr |
Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies |
| title_full_unstemmed |
Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies |
| title_short |
Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies |
| title_sort |
late-stage diagnosis of hiv infection in brazilian children: evidence from two national cohort studies |
| topic |
Public Health, Environmental and Occupational Health |
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http://dx.doi.org/10.1590/s0102-311x2013000700004 |
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2013 |
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1291-1300 |
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<jats:p>This study analyzed data from two consecutive retrospective cohort samples (1983 to 1998 and 1999 to 2002) of Brazilian children with AIDS (N = 1,758) through mother-to-child-transmission. Late-stage diagnosis (CDC category C) was investigated in relation to the following variables: year of birth, year of HIV diagnosis, and time periods related to changes in government treatment guidelines. Late-stage diagnosis occurred in 731 (41.6%) of cases and was more prevalent in infants under 12 months of age. The rate of late-stage diagnosis decreased from 48% to 36% between the two periods studied. We also observed a reduction in the proportion of late-stage diagnoses and the time lapse between HIV diagnosis and ART initiation. A significant association was found between timely diagnosis and having been born in recent years (OR = 0.62; p = 0.009) and year of HIV diagnosis (OR = 0.72; p = 0.002/OR = 0.62; p < 0.001). Infants under the age of 12 months were more likely to be diagnosed at a late stage than older children (OR = 1.70; p = 0.004). Despite advances, there is a need to improve the effectiveness of policies and programs focused on improving early diagnosis and management of HIV/AIDS.</jats:p> |
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| author | Ramos Jr., Alberto Novaes, Matida, Luiza Harunari, Alencar, Carlos Henrique, Hearst, Norman, Heukelbach, Jorg |
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| description | <jats:p>This study analyzed data from two consecutive retrospective cohort samples (1983 to 1998 and 1999 to 2002) of Brazilian children with AIDS (N = 1,758) through mother-to-child-transmission. Late-stage diagnosis (CDC category C) was investigated in relation to the following variables: year of birth, year of HIV diagnosis, and time periods related to changes in government treatment guidelines. Late-stage diagnosis occurred in 731 (41.6%) of cases and was more prevalent in infants under 12 months of age. The rate of late-stage diagnosis decreased from 48% to 36% between the two periods studied. We also observed a reduction in the proportion of late-stage diagnoses and the time lapse between HIV diagnosis and ART initiation. A significant association was found between timely diagnosis and having been born in recent years (OR = 0.62; p = 0.009) and year of HIV diagnosis (OR = 0.72; p = 0.002/OR = 0.62; p < 0.001). Infants under the age of 12 months were more likely to be diagnosed at a late stage than older children (OR = 1.70; p = 0.004). Despite advances, there is a need to improve the effectiveness of policies and programs focused on improving early diagnosis and management of HIV/AIDS.</jats:p> |
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| spelling | Ramos Jr., Alberto Novaes Matida, Luiza Harunari Alencar, Carlos Henrique Hearst, Norman Heukelbach, Jorg 0102-311X FapUNIFESP (SciELO) Public Health, Environmental and Occupational Health http://dx.doi.org/10.1590/s0102-311x2013000700004 <jats:p>This study analyzed data from two consecutive retrospective cohort samples (1983 to 1998 and 1999 to 2002) of Brazilian children with AIDS (N = 1,758) through mother-to-child-transmission. Late-stage diagnosis (CDC category C) was investigated in relation to the following variables: year of birth, year of HIV diagnosis, and time periods related to changes in government treatment guidelines. Late-stage diagnosis occurred in 731 (41.6%) of cases and was more prevalent in infants under 12 months of age. The rate of late-stage diagnosis decreased from 48% to 36% between the two periods studied. We also observed a reduction in the proportion of late-stage diagnoses and the time lapse between HIV diagnosis and ART initiation. A significant association was found between timely diagnosis and having been born in recent years (OR = 0.62; p = 0.009) and year of HIV diagnosis (OR = 0.72; p = 0.002/OR = 0.62; p < 0.001). Infants under the age of 12 months were more likely to be diagnosed at a late stage than older children (OR = 1.70; p = 0.004). Despite advances, there is a need to improve the effectiveness of policies and programs focused on improving early diagnosis and management of HIV/AIDS.</jats:p> Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies Cadernos de Saúde Pública |
| spellingShingle | Ramos Jr., Alberto Novaes, Matida, Luiza Harunari, Alencar, Carlos Henrique, Hearst, Norman, Heukelbach, Jorg, Cadernos de Saúde Pública, Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies, Public Health, Environmental and Occupational Health |
| title | Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies |
| title_full | Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies |
| title_fullStr | Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies |
| title_full_unstemmed | Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies |
| title_short | Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies |
| title_sort | late-stage diagnosis of hiv infection in brazilian children: evidence from two national cohort studies |
| title_unstemmed | Late-stage diagnosis of HIV infection in Brazilian children: evidence from two national cohort studies |
| topic | Public Health, Environmental and Occupational Health |
| url | http://dx.doi.org/10.1590/s0102-311x2013000700004 |