author_facet Ng, Sheryl Hui Xian
Rahman, Nabilah
Ang, Ian Yi Han
Sridharan, Srinath
Ramachandran, Sravan
Wang, Debby Dan
Khoo, Astrid
Tan, Chuen Seng
Feng, Mengling
Toh, Sue-Anne Ee Shiow
Tan, Xin Quan
Ng, Sheryl Hui Xian
Rahman, Nabilah
Ang, Ian Yi Han
Sridharan, Srinath
Ramachandran, Sravan
Wang, Debby Dan
Khoo, Astrid
Tan, Chuen Seng
Feng, Mengling
Toh, Sue-Anne Ee Shiow
Tan, Xin Quan
author Ng, Sheryl Hui Xian
Rahman, Nabilah
Ang, Ian Yi Han
Sridharan, Srinath
Ramachandran, Sravan
Wang, Debby Dan
Khoo, Astrid
Tan, Chuen Seng
Feng, Mengling
Toh, Sue-Anne Ee Shiow
Tan, Xin Quan
spellingShingle Ng, Sheryl Hui Xian
Rahman, Nabilah
Ang, Ian Yi Han
Sridharan, Srinath
Ramachandran, Sravan
Wang, Debby Dan
Khoo, Astrid
Tan, Chuen Seng
Feng, Mengling
Toh, Sue-Anne Ee Shiow
Tan, Xin Quan
BMJ Open
Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
General Medicine
author_sort ng, sheryl hui xian
spelling Ng, Sheryl Hui Xian Rahman, Nabilah Ang, Ian Yi Han Sridharan, Srinath Ramachandran, Sravan Wang, Debby Dan Khoo, Astrid Tan, Chuen Seng Feng, Mengling Toh, Sue-Anne Ee Shiow Tan, Xin Quan 2044-6055 2044-6055 BMJ General Medicine http://dx.doi.org/10.1136/bmjopen-2019-031622 <jats:sec><jats:title>Objective</jats:title><jats:p>We aim to characterise persistent high utilisers (PHUs) of healthcare services, and correspondingly, transient high utilisers (THUs) and non-high utilisers (non-HUs) for comparison, to facilitate stratifying HUs for targeted intervention. Subsequently we apply machine learning algorithms to predict which HUs will persist as PHUs, to inform future trials testing the effectiveness of interventions in reducing healthcare utilisation in PHUs.</jats:p></jats:sec><jats:sec><jats:title>Design and setting</jats:title><jats:p>This is a retrospective cohort study using administrative data from an Academic Medical Centre (AMC) in Singapore.</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>Patients who had at least one inpatient admission to the AMC between 2005 and 2013 were included in this study. HUs incurred Singapore Dollar 8150 or more within a year. PHUs were defined as HUs for three consecutive years, while THUs were HUs for 1 or 2 years. Non-HUs did not incur high healthcare costs at any point during the study period.</jats:p></jats:sec><jats:sec><jats:title>Outcome measures</jats:title><jats:p>PHU status at the end of the third year was the outcome of interest. Socio-demographic profiles, clinical complexity and utilisation metrics of each group were reported. Area under curve (AUC) was used to identify the best model to predict persistence.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>PHUs were older and had higher comorbidity and mortality. Over the three observed years, PHUs’ expenditure generally increased, while THUs and non-HUs’ spending and inpatient utilisation decreased. The predictive model exhibited good performance during both internal (AUC: 83.2%, 95% CI: 82.2% to 84.2%) and external validation (AUC: 79.8%, 95% CI: 78.8% to 80.8%).</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>The HU population could be stratified into PHUs and THUs, with distinctly different utilisation trajectories. We developed a model that could predict at the end of 1 year, whether a patient in our population will continue to be a HU in the next 2 years. This knowledge would allow healthcare providers to target PHUs in our health system with interventions in a cost-effective manner.</jats:p></jats:sec> Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore BMJ Open
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title Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
title_unstemmed Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
title_full Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
title_fullStr Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
title_full_unstemmed Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
title_short Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
title_sort characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in singapore
topic General Medicine
url http://dx.doi.org/10.1136/bmjopen-2019-031622
publishDate 2020
physical e031622
description <jats:sec><jats:title>Objective</jats:title><jats:p>We aim to characterise persistent high utilisers (PHUs) of healthcare services, and correspondingly, transient high utilisers (THUs) and non-high utilisers (non-HUs) for comparison, to facilitate stratifying HUs for targeted intervention. Subsequently we apply machine learning algorithms to predict which HUs will persist as PHUs, to inform future trials testing the effectiveness of interventions in reducing healthcare utilisation in PHUs.</jats:p></jats:sec><jats:sec><jats:title>Design and setting</jats:title><jats:p>This is a retrospective cohort study using administrative data from an Academic Medical Centre (AMC) in Singapore.</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>Patients who had at least one inpatient admission to the AMC between 2005 and 2013 were included in this study. HUs incurred Singapore Dollar 8150 or more within a year. PHUs were defined as HUs for three consecutive years, while THUs were HUs for 1 or 2 years. Non-HUs did not incur high healthcare costs at any point during the study period.</jats:p></jats:sec><jats:sec><jats:title>Outcome measures</jats:title><jats:p>PHU status at the end of the third year was the outcome of interest. Socio-demographic profiles, clinical complexity and utilisation metrics of each group were reported. Area under curve (AUC) was used to identify the best model to predict persistence.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>PHUs were older and had higher comorbidity and mortality. Over the three observed years, PHUs’ expenditure generally increased, while THUs and non-HUs’ spending and inpatient utilisation decreased. The predictive model exhibited good performance during both internal (AUC: 83.2%, 95% CI: 82.2% to 84.2%) and external validation (AUC: 79.8%, 95% CI: 78.8% to 80.8%).</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>The HU population could be stratified into PHUs and THUs, with distinctly different utilisation trajectories. We developed a model that could predict at the end of 1 year, whether a patient in our population will continue to be a HU in the next 2 years. This knowledge would allow healthcare providers to target PHUs in our health system with interventions in a cost-effective manner.</jats:p></jats:sec>
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author Ng, Sheryl Hui Xian, Rahman, Nabilah, Ang, Ian Yi Han, Sridharan, Srinath, Ramachandran, Sravan, Wang, Debby Dan, Khoo, Astrid, Tan, Chuen Seng, Feng, Mengling, Toh, Sue-Anne Ee Shiow, Tan, Xin Quan
author_facet Ng, Sheryl Hui Xian, Rahman, Nabilah, Ang, Ian Yi Han, Sridharan, Srinath, Ramachandran, Sravan, Wang, Debby Dan, Khoo, Astrid, Tan, Chuen Seng, Feng, Mengling, Toh, Sue-Anne Ee Shiow, Tan, Xin Quan, Ng, Sheryl Hui Xian, Rahman, Nabilah, Ang, Ian Yi Han, Sridharan, Srinath, Ramachandran, Sravan, Wang, Debby Dan, Khoo, Astrid, Tan, Chuen Seng, Feng, Mengling, Toh, Sue-Anne Ee Shiow, Tan, Xin Quan
author_sort ng, sheryl hui xian
container_issue 1
container_start_page 0
container_title BMJ Open
container_volume 10
description <jats:sec><jats:title>Objective</jats:title><jats:p>We aim to characterise persistent high utilisers (PHUs) of healthcare services, and correspondingly, transient high utilisers (THUs) and non-high utilisers (non-HUs) for comparison, to facilitate stratifying HUs for targeted intervention. Subsequently we apply machine learning algorithms to predict which HUs will persist as PHUs, to inform future trials testing the effectiveness of interventions in reducing healthcare utilisation in PHUs.</jats:p></jats:sec><jats:sec><jats:title>Design and setting</jats:title><jats:p>This is a retrospective cohort study using administrative data from an Academic Medical Centre (AMC) in Singapore.</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>Patients who had at least one inpatient admission to the AMC between 2005 and 2013 were included in this study. HUs incurred Singapore Dollar 8150 or more within a year. PHUs were defined as HUs for three consecutive years, while THUs were HUs for 1 or 2 years. Non-HUs did not incur high healthcare costs at any point during the study period.</jats:p></jats:sec><jats:sec><jats:title>Outcome measures</jats:title><jats:p>PHU status at the end of the third year was the outcome of interest. Socio-demographic profiles, clinical complexity and utilisation metrics of each group were reported. Area under curve (AUC) was used to identify the best model to predict persistence.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>PHUs were older and had higher comorbidity and mortality. Over the three observed years, PHUs’ expenditure generally increased, while THUs and non-HUs’ spending and inpatient utilisation decreased. The predictive model exhibited good performance during both internal (AUC: 83.2%, 95% CI: 82.2% to 84.2%) and external validation (AUC: 79.8%, 95% CI: 78.8% to 80.8%).</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>The HU population could be stratified into PHUs and THUs, with distinctly different utilisation trajectories. We developed a model that could predict at the end of 1 year, whether a patient in our population will continue to be a HU in the next 2 years. This knowledge would allow healthcare providers to target PHUs in our health system with interventions in a cost-effective manner.</jats:p></jats:sec>
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spelling Ng, Sheryl Hui Xian Rahman, Nabilah Ang, Ian Yi Han Sridharan, Srinath Ramachandran, Sravan Wang, Debby Dan Khoo, Astrid Tan, Chuen Seng Feng, Mengling Toh, Sue-Anne Ee Shiow Tan, Xin Quan 2044-6055 2044-6055 BMJ General Medicine http://dx.doi.org/10.1136/bmjopen-2019-031622 <jats:sec><jats:title>Objective</jats:title><jats:p>We aim to characterise persistent high utilisers (PHUs) of healthcare services, and correspondingly, transient high utilisers (THUs) and non-high utilisers (non-HUs) for comparison, to facilitate stratifying HUs for targeted intervention. Subsequently we apply machine learning algorithms to predict which HUs will persist as PHUs, to inform future trials testing the effectiveness of interventions in reducing healthcare utilisation in PHUs.</jats:p></jats:sec><jats:sec><jats:title>Design and setting</jats:title><jats:p>This is a retrospective cohort study using administrative data from an Academic Medical Centre (AMC) in Singapore.</jats:p></jats:sec><jats:sec><jats:title>Participants</jats:title><jats:p>Patients who had at least one inpatient admission to the AMC between 2005 and 2013 were included in this study. HUs incurred Singapore Dollar 8150 or more within a year. PHUs were defined as HUs for three consecutive years, while THUs were HUs for 1 or 2 years. Non-HUs did not incur high healthcare costs at any point during the study period.</jats:p></jats:sec><jats:sec><jats:title>Outcome measures</jats:title><jats:p>PHU status at the end of the third year was the outcome of interest. Socio-demographic profiles, clinical complexity and utilisation metrics of each group were reported. Area under curve (AUC) was used to identify the best model to predict persistence.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>PHUs were older and had higher comorbidity and mortality. Over the three observed years, PHUs’ expenditure generally increased, while THUs and non-HUs’ spending and inpatient utilisation decreased. The predictive model exhibited good performance during both internal (AUC: 83.2%, 95% CI: 82.2% to 84.2%) and external validation (AUC: 79.8%, 95% CI: 78.8% to 80.8%).</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>The HU population could be stratified into PHUs and THUs, with distinctly different utilisation trajectories. We developed a model that could predict at the end of 1 year, whether a patient in our population will continue to be a HU in the next 2 years. This knowledge would allow healthcare providers to target PHUs in our health system with interventions in a cost-effective manner.</jats:p></jats:sec> Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore BMJ Open
spellingShingle Ng, Sheryl Hui Xian, Rahman, Nabilah, Ang, Ian Yi Han, Sridharan, Srinath, Ramachandran, Sravan, Wang, Debby Dan, Khoo, Astrid, Tan, Chuen Seng, Feng, Mengling, Toh, Sue-Anne Ee Shiow, Tan, Xin Quan, BMJ Open, Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore, General Medicine
title Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
title_full Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
title_fullStr Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
title_full_unstemmed Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
title_short Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
title_sort characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in singapore
title_unstemmed Characterising and predicting persistent high-cost utilisers in healthcare: a retrospective cohort study in Singapore
topic General Medicine
url http://dx.doi.org/10.1136/bmjopen-2019-031622