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New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve
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| Zeitschriftentitel: | Antimicrobial Agents and Chemotherapy |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Antimicrobial Agents and Chemotherapy, 46, 2002, 12, S. 4016-4018 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Society for Microbiology
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| Schlagwörter: |
| author_facet |
Chryssanthou, Erja Cars, Otto Sjölin, Jan Chryssanthou, Erja Cars, Otto Sjölin, Jan |
|---|---|
| author |
Chryssanthou, Erja Cars, Otto Sjölin, Jan |
| spellingShingle |
Chryssanthou, Erja Cars, Otto Sjölin, Jan Antimicrobial Agents and Chemotherapy New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve Infectious Diseases Pharmacology (medical) Pharmacology |
| author_sort |
chryssanthou, erja |
| spelling |
Chryssanthou, Erja Cars, Otto Sjölin, Jan 0066-4804 1098-6596 American Society for Microbiology Infectious Diseases Pharmacology (medical) Pharmacology http://dx.doi.org/10.1128/aac.46.12.4016-4018.2002 <jats:title>ABSTRACT</jats:title><jats:p>The postantifungal effect (PAFE) of amphotericin B was determined with a BacT/Alert automated system, which is based on the colorimetric detection of CO<jats:sub>2</jats:sub>. The levels of accuracy and precision of the automated method were high. Longer PAFEs were obtained for<jats:italic>Candida</jats:italic><jats:italic>albicans</jats:italic>(<jats:italic>P</jats:italic>< 0.001),<jats:italic>C. glabrata</jats:italic>(<jats:italic>P</jats:italic>< 0.01), and<jats:italic>C. krusei</jats:italic>(<jats:italic>P</jats:italic>< 0.01) at increasing amphotericin B concentrations and exposure times.</jats:p> New Automated Method for Determining Postantifungal Effect of Amphotericin B against<i>Candida</i>Species: Effects of Concentration, Exposure Time, and Area under the Curve Antimicrobial Agents and Chemotherapy |
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10.1128/aac.46.12.4016-4018.2002 |
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American Society for Microbiology, 2002 |
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| title |
New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve |
| title_unstemmed |
New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve |
| title_full |
New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve |
| title_fullStr |
New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve |
| title_full_unstemmed |
New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve |
| title_short |
New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve |
| title_sort |
new automated method for determining postantifungal effect of amphotericin b against<i>candida</i>species: effects of concentration, exposure time, and area under the curve |
| topic |
Infectious Diseases Pharmacology (medical) Pharmacology |
| url |
http://dx.doi.org/10.1128/aac.46.12.4016-4018.2002 |
| publishDate |
2002 |
| physical |
4016-4018 |
| description |
<jats:title>ABSTRACT</jats:title><jats:p>The postantifungal effect (PAFE) of amphotericin B was determined with a BacT/Alert automated system, which is based on the colorimetric detection of CO<jats:sub>2</jats:sub>. The levels of accuracy and precision of the automated method were high. Longer PAFEs were obtained for<jats:italic>Candida</jats:italic><jats:italic>albicans</jats:italic>(<jats:italic>P</jats:italic>< 0.001),<jats:italic>C. glabrata</jats:italic>(<jats:italic>P</jats:italic>< 0.01), and<jats:italic>C. krusei</jats:italic>(<jats:italic>P</jats:italic>< 0.01) at increasing amphotericin B concentrations and exposure times.</jats:p> |
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| author | Chryssanthou, Erja, Cars, Otto, Sjölin, Jan |
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| description | <jats:title>ABSTRACT</jats:title><jats:p>The postantifungal effect (PAFE) of amphotericin B was determined with a BacT/Alert automated system, which is based on the colorimetric detection of CO<jats:sub>2</jats:sub>. The levels of accuracy and precision of the automated method were high. Longer PAFEs were obtained for<jats:italic>Candida</jats:italic><jats:italic>albicans</jats:italic>(<jats:italic>P</jats:italic>< 0.001),<jats:italic>C. glabrata</jats:italic>(<jats:italic>P</jats:italic>< 0.01), and<jats:italic>C. krusei</jats:italic>(<jats:italic>P</jats:italic>< 0.01) at increasing amphotericin B concentrations and exposure times.</jats:p> |
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| spelling | Chryssanthou, Erja Cars, Otto Sjölin, Jan 0066-4804 1098-6596 American Society for Microbiology Infectious Diseases Pharmacology (medical) Pharmacology http://dx.doi.org/10.1128/aac.46.12.4016-4018.2002 <jats:title>ABSTRACT</jats:title><jats:p>The postantifungal effect (PAFE) of amphotericin B was determined with a BacT/Alert automated system, which is based on the colorimetric detection of CO<jats:sub>2</jats:sub>. The levels of accuracy and precision of the automated method were high. Longer PAFEs were obtained for<jats:italic>Candida</jats:italic><jats:italic>albicans</jats:italic>(<jats:italic>P</jats:italic>< 0.001),<jats:italic>C. glabrata</jats:italic>(<jats:italic>P</jats:italic>< 0.01), and<jats:italic>C. krusei</jats:italic>(<jats:italic>P</jats:italic>< 0.01) at increasing amphotericin B concentrations and exposure times.</jats:p> New Automated Method for Determining Postantifungal Effect of Amphotericin B against<i>Candida</i>Species: Effects of Concentration, Exposure Time, and Area under the Curve Antimicrobial Agents and Chemotherapy |
| spellingShingle | Chryssanthou, Erja, Cars, Otto, Sjölin, Jan, Antimicrobial Agents and Chemotherapy, New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve, Infectious Diseases, Pharmacology (medical), Pharmacology |
| title | New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve |
| title_full | New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve |
| title_fullStr | New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve |
| title_full_unstemmed | New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve |
| title_short | New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve |
| title_sort | new automated method for determining postantifungal effect of amphotericin b against<i>candida</i>species: effects of concentration, exposure time, and area under the curve |
| title_unstemmed | New Automated Method for Determining Postantifungal Effect of Amphotericin B againstCandidaSpecies: Effects of Concentration, Exposure Time, and Area under the Curve |
| topic | Infectious Diseases, Pharmacology (medical), Pharmacology |
| url | http://dx.doi.org/10.1128/aac.46.12.4016-4018.2002 |