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Brown, R B
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Brown, R B
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Use of rifampin in nonstaphylococcal, nonmycobacterial disease
Infectious Diseases
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spelling Morris, A B Brown, R B Sands, M 0066-4804 1098-6596 American Society for Microbiology Infectious Diseases Pharmacology (medical) Pharmacology http://dx.doi.org/10.1128/aac.37.1.1 <jats:p>Rifampin has very broad antimicrobial properties with in vitro activities against many bacteria, mycobacteria, higher bacteria, chlamydia, fungi, parasites, and viruses (Table 1). The clinical use of rifampin is more limited, in part because of the lack of in vivo human clinical studies demonstrating its efficacy. Investigators have valid concerns regarding the emergence of resistance of mycobacteria if widespread use of rifampin becomes common, although this has not been well documented. Because rifampin obtains therapeutic levels intracellularly and is distributed widely throughout the body, the antibiotic potentially could be used on a broader scale, but more studies will be needed to demonstrate its clinical utility.</jats:p> Use of rifampin in nonstaphylococcal, nonmycobacterial disease Antimicrobial Agents and Chemotherapy
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title Use of rifampin in nonstaphylococcal, nonmycobacterial disease
title_unstemmed Use of rifampin in nonstaphylococcal, nonmycobacterial disease
title_full Use of rifampin in nonstaphylococcal, nonmycobacterial disease
title_fullStr Use of rifampin in nonstaphylococcal, nonmycobacterial disease
title_full_unstemmed Use of rifampin in nonstaphylococcal, nonmycobacterial disease
title_short Use of rifampin in nonstaphylococcal, nonmycobacterial disease
title_sort use of rifampin in nonstaphylococcal, nonmycobacterial disease
topic Infectious Diseases
Pharmacology (medical)
Pharmacology
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spelling Morris, A B Brown, R B Sands, M 0066-4804 1098-6596 American Society for Microbiology Infectious Diseases Pharmacology (medical) Pharmacology http://dx.doi.org/10.1128/aac.37.1.1 <jats:p>Rifampin has very broad antimicrobial properties with in vitro activities against many bacteria, mycobacteria, higher bacteria, chlamydia, fungi, parasites, and viruses (Table 1). The clinical use of rifampin is more limited, in part because of the lack of in vivo human clinical studies demonstrating its efficacy. Investigators have valid concerns regarding the emergence of resistance of mycobacteria if widespread use of rifampin becomes common, although this has not been well documented. Because rifampin obtains therapeutic levels intracellularly and is distributed widely throughout the body, the antibiotic potentially could be used on a broader scale, but more studies will be needed to demonstrate its clinical utility.</jats:p> Use of rifampin in nonstaphylococcal, nonmycobacterial disease Antimicrobial Agents and Chemotherapy
spellingShingle Morris, A B, Brown, R B, Sands, M, Antimicrobial Agents and Chemotherapy, Use of rifampin in nonstaphylococcal, nonmycobacterial disease, Infectious Diseases, Pharmacology (medical), Pharmacology
title Use of rifampin in nonstaphylococcal, nonmycobacterial disease
title_full Use of rifampin in nonstaphylococcal, nonmycobacterial disease
title_fullStr Use of rifampin in nonstaphylococcal, nonmycobacterial disease
title_full_unstemmed Use of rifampin in nonstaphylococcal, nonmycobacterial disease
title_short Use of rifampin in nonstaphylococcal, nonmycobacterial disease
title_sort use of rifampin in nonstaphylococcal, nonmycobacterial disease
title_unstemmed Use of rifampin in nonstaphylococcal, nonmycobacterial disease
topic Infectious Diseases, Pharmacology (medical), Pharmacology
url http://dx.doi.org/10.1128/aac.37.1.1