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Drug and Neurotransmitter Receptors in the Brain
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| Zeitschriftentitel: | Science |
|---|---|
| Personen und Körperschaften: | |
| In: | Science, 224, 1984, 4644, S. 22-31 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Association for the Advancement of Science (AAAS)
|
| Schlagwörter: |
| author_facet |
Snyder, Solomon H. Snyder, Solomon H. |
|---|---|
| author |
Snyder, Solomon H. |
| spellingShingle |
Snyder, Solomon H. Science Drug and Neurotransmitter Receptors in the Brain Multidisciplinary |
| author_sort |
snyder, solomon h. |
| spelling |
Snyder, Solomon H. 0036-8075 1095-9203 American Association for the Advancement of Science (AAAS) Multidisciplinary http://dx.doi.org/10.1126/science.6322304 <jats:p>Biochemical investigation of receptors for neurotransmitters and drugs in the brain has been one of the most active areas of molecular neuroscience during the past decade. This work has permitted fundamental insights into how binding of neurotransmitters to their receptors excites or inhibits neuronal firing or changes cellular metabolism. The recognition of receptor subtypes has suggested subtle ways for neurotransmitters to modulate neuronal functioning. Finally, the ability to measure receptor sites in simple test tube systems and to distinguish readily between agonists and antagonists has provided useful probes for drug discovery programs.</jats:p> Drug and Neurotransmitter Receptors in the Brain Science |
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American Association for the Advancement of Science (AAAS), 1984 |
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American Association for the Advancement of Science (AAAS), 1984 |
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0036-8075 1095-9203 |
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1984 |
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American Association for the Advancement of Science (AAAS) |
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Science |
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49 |
| title |
Drug and Neurotransmitter Receptors in the Brain |
| title_unstemmed |
Drug and Neurotransmitter Receptors in the Brain |
| title_full |
Drug and Neurotransmitter Receptors in the Brain |
| title_fullStr |
Drug and Neurotransmitter Receptors in the Brain |
| title_full_unstemmed |
Drug and Neurotransmitter Receptors in the Brain |
| title_short |
Drug and Neurotransmitter Receptors in the Brain |
| title_sort |
drug and neurotransmitter receptors in the brain |
| topic |
Multidisciplinary |
| url |
http://dx.doi.org/10.1126/science.6322304 |
| publishDate |
1984 |
| physical |
22-31 |
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<jats:p>Biochemical investigation of receptors for neurotransmitters and drugs in the brain has been one of the most active areas of molecular neuroscience during the past decade. This work has permitted fundamental insights into how binding of neurotransmitters to their receptors excites or inhibits neuronal firing or changes cellular metabolism. The recognition of receptor subtypes has suggested subtle ways for neurotransmitters to modulate neuronal functioning. Finally, the ability to measure receptor sites in simple test tube systems and to distinguish readily between agonists and antagonists has provided useful probes for drug discovery programs.</jats:p> |
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| author | Snyder, Solomon H. |
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| container_issue | 4644 |
| container_start_page | 22 |
| container_title | Science |
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| description | <jats:p>Biochemical investigation of receptors for neurotransmitters and drugs in the brain has been one of the most active areas of molecular neuroscience during the past decade. This work has permitted fundamental insights into how binding of neurotransmitters to their receptors excites or inhibits neuronal firing or changes cellular metabolism. The recognition of receptor subtypes has suggested subtle ways for neurotransmitters to modulate neuronal functioning. Finally, the ability to measure receptor sites in simple test tube systems and to distinguish readily between agonists and antagonists has provided useful probes for drug discovery programs.</jats:p> |
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| imprint | American Association for the Advancement of Science (AAAS), 1984 |
| imprint_str_mv | American Association for the Advancement of Science (AAAS), 1984 |
| institution | DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Gla1, DE-Zi4 |
| issn | 0036-8075, 1095-9203 |
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| physical | 22-31 |
| publishDate | 1984 |
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| publisher | American Association for the Advancement of Science (AAAS) |
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| series | Science |
| source_id | 49 |
| spelling | Snyder, Solomon H. 0036-8075 1095-9203 American Association for the Advancement of Science (AAAS) Multidisciplinary http://dx.doi.org/10.1126/science.6322304 <jats:p>Biochemical investigation of receptors for neurotransmitters and drugs in the brain has been one of the most active areas of molecular neuroscience during the past decade. This work has permitted fundamental insights into how binding of neurotransmitters to their receptors excites or inhibits neuronal firing or changes cellular metabolism. The recognition of receptor subtypes has suggested subtle ways for neurotransmitters to modulate neuronal functioning. Finally, the ability to measure receptor sites in simple test tube systems and to distinguish readily between agonists and antagonists has provided useful probes for drug discovery programs.</jats:p> Drug and Neurotransmitter Receptors in the Brain Science |
| spellingShingle | Snyder, Solomon H., Science, Drug and Neurotransmitter Receptors in the Brain, Multidisciplinary |
| title | Drug and Neurotransmitter Receptors in the Brain |
| title_full | Drug and Neurotransmitter Receptors in the Brain |
| title_fullStr | Drug and Neurotransmitter Receptors in the Brain |
| title_full_unstemmed | Drug and Neurotransmitter Receptors in the Brain |
| title_short | Drug and Neurotransmitter Receptors in the Brain |
| title_sort | drug and neurotransmitter receptors in the brain |
| title_unstemmed | Drug and Neurotransmitter Receptors in the Brain |
| topic | Multidisciplinary |
| url | http://dx.doi.org/10.1126/science.6322304 |