author_facet Chen, Y
Chen, Y
author Chen, Y
spellingShingle Chen, Y
Medical Physics
SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
General Medicine
author_sort chen, y
spelling Chen, Y 0094-2405 2473-4209 Wiley General Medicine http://dx.doi.org/10.1118/1.4924219 <jats:sec><jats:title>Purpose:</jats:title><jats:p>To improve the quality of kV X‐ray cone beam CT (CBCT) for use in radiotherapy delivery assessment and re‐planning by using penalized likelihood (PL) iterative reconstruction and auto‐segmentation accuracy of the resulting CBCTs as an image quality metric.</jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p>Present filtered backprojection (FBP) CBCT reconstructions can be improved upon by PL reconstruction with image formation models and appropriate regularization constraints. We use two constraints: 1) image smoothing via an edge preserving filter, and 2) a constraint minimizing the differences between the reconstruction and a registered prior image. Reconstructions of prostate therapy CBCTs were computed with constraint 1 alone and with both constraints. The prior images were planning CTs(pCT) deformable‐registered to the FBP reconstructions. Anatomy segmentations were done using atlas‐based auto‐segmentation (Elekta ADMIRE).</jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p>We observed small but consistent improvements in the Dice similarity coefficients of PL reconstructions over the FBP results, and additional small improvements with the added prior image constraint. For a CBCT with anatomy very similar in appearance to the pCT, we observed these changes in the Dice metric: +2.9% (prostate), +8.6% (rectum), −1.9% (bladder). For a second CBCT with a very different rectum configuration, we observed +0.8% (prostate), +8.9% (rectum), −1.2% (bladder). For a third case with significant lateral truncation of the field of view, we observed: +0.8% (prostate), +8.9% (rectum), −1.2% (bladder). Adding the prior image constraint raised Dice measures by about 1%.</jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p>Efficient and practical adaptive radiotherapy requires accurate deformable registration and accurate anatomy delineation. We show here small and consistent patterns of improved contour accuracy using PL iterative reconstruction compared with FBP reconstruction. However, the modest extent of these results and the pattern of differences across CBCT cases suggest that significant further development will be required to make CBCT useful to adaptive radiotherapy.</jats:p></jats:sec> SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction Medical Physics
doi_str_mv 10.1118/1.4924219
facet_avail Online
format ElectronicArticle
fullrecord blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExOC8xLjQ5MjQyMTk
id ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExOC8xLjQ5MjQyMTk
institution DE-Zi4
DE-Gla1
DE-15
DE-Pl11
DE-Rs1
DE-14
DE-105
DE-Ch1
DE-L229
DE-D275
DE-Bn3
DE-Brt1
DE-D161
imprint Wiley, 2015
imprint_str_mv Wiley, 2015
issn 0094-2405
2473-4209
issn_str_mv 0094-2405
2473-4209
language English
mega_collection Wiley (CrossRef)
match_str chen2015suej133autosegmentationoflinaccbctimprovedaccuracyviapenalizedlikelihoodreconstruction
publishDateSort 2015
publisher Wiley
recordtype ai
record_format ai
series Medical Physics
source_id 49
title SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
title_unstemmed SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
title_full SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
title_fullStr SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
title_full_unstemmed SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
title_short SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
title_sort su‐e‐j‐133: autosegmentation of linac cbct: improved accuracy via penalized likelihood reconstruction
topic General Medicine
url http://dx.doi.org/10.1118/1.4924219
publishDate 2015
physical 3295-3295
description <jats:sec><jats:title>Purpose:</jats:title><jats:p>To improve the quality of kV X‐ray cone beam CT (CBCT) for use in radiotherapy delivery assessment and re‐planning by using penalized likelihood (PL) iterative reconstruction and auto‐segmentation accuracy of the resulting CBCTs as an image quality metric.</jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p>Present filtered backprojection (FBP) CBCT reconstructions can be improved upon by PL reconstruction with image formation models and appropriate regularization constraints. We use two constraints: 1) image smoothing via an edge preserving filter, and 2) a constraint minimizing the differences between the reconstruction and a registered prior image. Reconstructions of prostate therapy CBCTs were computed with constraint 1 alone and with both constraints. The prior images were planning CTs(pCT) deformable‐registered to the FBP reconstructions. Anatomy segmentations were done using atlas‐based auto‐segmentation (Elekta ADMIRE).</jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p>We observed small but consistent improvements in the Dice similarity coefficients of PL reconstructions over the FBP results, and additional small improvements with the added prior image constraint. For a CBCT with anatomy very similar in appearance to the pCT, we observed these changes in the Dice metric: +2.9% (prostate), +8.6% (rectum), −1.9% (bladder). For a second CBCT with a very different rectum configuration, we observed +0.8% (prostate), +8.9% (rectum), −1.2% (bladder). For a third case with significant lateral truncation of the field of view, we observed: +0.8% (prostate), +8.9% (rectum), −1.2% (bladder). Adding the prior image constraint raised Dice measures by about 1%.</jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p>Efficient and practical adaptive radiotherapy requires accurate deformable registration and accurate anatomy delineation. We show here small and consistent patterns of improved contour accuracy using PL iterative reconstruction compared with FBP reconstruction. However, the modest extent of these results and the pattern of differences across CBCT cases suggest that significant further development will be required to make CBCT useful to adaptive radiotherapy.</jats:p></jats:sec>
container_issue 6Part9
container_start_page 3295
container_title Medical Physics
container_volume 42
format_de105 Article, E-Article
format_de14 Article, E-Article
format_de15 Article, E-Article
format_de520 Article, E-Article
format_de540 Article, E-Article
format_dech1 Article, E-Article
format_ded117 Article, E-Article
format_degla1 E-Article
format_del152 Buch
format_del189 Article, E-Article
format_dezi4 Article
format_dezwi2 Article, E-Article
format_finc Article, E-Article
format_nrw Article, E-Article
_version_ 1792335196532506626
geogr_code not assigned
last_indexed 2024-03-01T14:39:06.408Z
geogr_code_person not assigned
openURL url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=SU%E2%80%90E%E2%80%90J%E2%80%90133%3A+Autosegmentation+of+Linac+CBCT%3A+Improved+Accuracy+Via+Penalized+Likelihood+Reconstruction&rft.date=2015-06-01&genre=article&issn=2473-4209&volume=42&issue=6Part9&spage=3295&epage=3295&pages=3295-3295&jtitle=Medical+Physics&atitle=SU%E2%80%90E%E2%80%90J%E2%80%90133%3A+Autosegmentation+of+Linac+CBCT%3A+Improved+Accuracy+Via+Penalized+Likelihood+Reconstruction&aulast=Chen&aufirst=Y&rft_id=info%3Adoi%2F10.1118%2F1.4924219&rft.language%5B0%5D=eng
SOLR
_version_ 1792335196532506626
author Chen, Y
author_facet Chen, Y, Chen, Y
author_sort chen, y
container_issue 6Part9
container_start_page 3295
container_title Medical Physics
container_volume 42
description <jats:sec><jats:title>Purpose:</jats:title><jats:p>To improve the quality of kV X‐ray cone beam CT (CBCT) for use in radiotherapy delivery assessment and re‐planning by using penalized likelihood (PL) iterative reconstruction and auto‐segmentation accuracy of the resulting CBCTs as an image quality metric.</jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p>Present filtered backprojection (FBP) CBCT reconstructions can be improved upon by PL reconstruction with image formation models and appropriate regularization constraints. We use two constraints: 1) image smoothing via an edge preserving filter, and 2) a constraint minimizing the differences between the reconstruction and a registered prior image. Reconstructions of prostate therapy CBCTs were computed with constraint 1 alone and with both constraints. The prior images were planning CTs(pCT) deformable‐registered to the FBP reconstructions. Anatomy segmentations were done using atlas‐based auto‐segmentation (Elekta ADMIRE).</jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p>We observed small but consistent improvements in the Dice similarity coefficients of PL reconstructions over the FBP results, and additional small improvements with the added prior image constraint. For a CBCT with anatomy very similar in appearance to the pCT, we observed these changes in the Dice metric: +2.9% (prostate), +8.6% (rectum), −1.9% (bladder). For a second CBCT with a very different rectum configuration, we observed +0.8% (prostate), +8.9% (rectum), −1.2% (bladder). For a third case with significant lateral truncation of the field of view, we observed: +0.8% (prostate), +8.9% (rectum), −1.2% (bladder). Adding the prior image constraint raised Dice measures by about 1%.</jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p>Efficient and practical adaptive radiotherapy requires accurate deformable registration and accurate anatomy delineation. We show here small and consistent patterns of improved contour accuracy using PL iterative reconstruction compared with FBP reconstruction. However, the modest extent of these results and the pattern of differences across CBCT cases suggest that significant further development will be required to make CBCT useful to adaptive radiotherapy.</jats:p></jats:sec>
doi_str_mv 10.1118/1.4924219
facet_avail Online
format ElectronicArticle
format_de105 Article, E-Article
format_de14 Article, E-Article
format_de15 Article, E-Article
format_de520 Article, E-Article
format_de540 Article, E-Article
format_dech1 Article, E-Article
format_ded117 Article, E-Article
format_degla1 E-Article
format_del152 Buch
format_del189 Article, E-Article
format_dezi4 Article
format_dezwi2 Article, E-Article
format_finc Article, E-Article
format_nrw Article, E-Article
geogr_code not assigned
geogr_code_person not assigned
id ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExOC8xLjQ5MjQyMTk
imprint Wiley, 2015
imprint_str_mv Wiley, 2015
institution DE-Zi4, DE-Gla1, DE-15, DE-Pl11, DE-Rs1, DE-14, DE-105, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161
issn 0094-2405, 2473-4209
issn_str_mv 0094-2405, 2473-4209
language English
last_indexed 2024-03-01T14:39:06.408Z
match_str chen2015suej133autosegmentationoflinaccbctimprovedaccuracyviapenalizedlikelihoodreconstruction
mega_collection Wiley (CrossRef)
physical 3295-3295
publishDate 2015
publishDateSort 2015
publisher Wiley
record_format ai
recordtype ai
series Medical Physics
source_id 49
spelling Chen, Y 0094-2405 2473-4209 Wiley General Medicine http://dx.doi.org/10.1118/1.4924219 <jats:sec><jats:title>Purpose:</jats:title><jats:p>To improve the quality of kV X‐ray cone beam CT (CBCT) for use in radiotherapy delivery assessment and re‐planning by using penalized likelihood (PL) iterative reconstruction and auto‐segmentation accuracy of the resulting CBCTs as an image quality metric.</jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p>Present filtered backprojection (FBP) CBCT reconstructions can be improved upon by PL reconstruction with image formation models and appropriate regularization constraints. We use two constraints: 1) image smoothing via an edge preserving filter, and 2) a constraint minimizing the differences between the reconstruction and a registered prior image. Reconstructions of prostate therapy CBCTs were computed with constraint 1 alone and with both constraints. The prior images were planning CTs(pCT) deformable‐registered to the FBP reconstructions. Anatomy segmentations were done using atlas‐based auto‐segmentation (Elekta ADMIRE).</jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p>We observed small but consistent improvements in the Dice similarity coefficients of PL reconstructions over the FBP results, and additional small improvements with the added prior image constraint. For a CBCT with anatomy very similar in appearance to the pCT, we observed these changes in the Dice metric: +2.9% (prostate), +8.6% (rectum), −1.9% (bladder). For a second CBCT with a very different rectum configuration, we observed +0.8% (prostate), +8.9% (rectum), −1.2% (bladder). For a third case with significant lateral truncation of the field of view, we observed: +0.8% (prostate), +8.9% (rectum), −1.2% (bladder). Adding the prior image constraint raised Dice measures by about 1%.</jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p>Efficient and practical adaptive radiotherapy requires accurate deformable registration and accurate anatomy delineation. We show here small and consistent patterns of improved contour accuracy using PL iterative reconstruction compared with FBP reconstruction. However, the modest extent of these results and the pattern of differences across CBCT cases suggest that significant further development will be required to make CBCT useful to adaptive radiotherapy.</jats:p></jats:sec> SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction Medical Physics
spellingShingle Chen, Y, Medical Physics, SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction, General Medicine
title SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
title_full SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
title_fullStr SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
title_full_unstemmed SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
title_short SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
title_sort su‐e‐j‐133: autosegmentation of linac cbct: improved accuracy via penalized likelihood reconstruction
title_unstemmed SU‐E‐J‐133: Autosegmentation of Linac CBCT: Improved Accuracy Via Penalized Likelihood Reconstruction
topic General Medicine
url http://dx.doi.org/10.1118/1.4924219