Eintrag weiter verarbeiten
Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED)
Gespeichert in:
| Zeitschriftentitel: | Paediatric and Perinatal Epidemiology |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , , |
| In: | Paediatric and Perinatal Epidemiology, 31, 2017, 6, S. 573-582 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Singer, Alison B. Aylsworth, Arthur S. Cordero, Christina Croen, Lisa A. DiGuiseppi, Carolyn Fallin, M. Daniele Herring, Amy H. Hooper, Stephen R. Pretzel, Rebecca E. Schieve, Laura A. Windham, Gayle C. Daniels, Julie L. Singer, Alison B. Aylsworth, Arthur S. Cordero, Christina Croen, Lisa A. DiGuiseppi, Carolyn Fallin, M. Daniele Herring, Amy H. Hooper, Stephen R. Pretzel, Rebecca E. Schieve, Laura A. Windham, Gayle C. Daniels, Julie L. |
|---|---|
| author |
Singer, Alison B. Aylsworth, Arthur S. Cordero, Christina Croen, Lisa A. DiGuiseppi, Carolyn Fallin, M. Daniele Herring, Amy H. Hooper, Stephen R. Pretzel, Rebecca E. Schieve, Laura A. Windham, Gayle C. Daniels, Julie L. |
| spellingShingle |
Singer, Alison B. Aylsworth, Arthur S. Cordero, Christina Croen, Lisa A. DiGuiseppi, Carolyn Fallin, M. Daniele Herring, Amy H. Hooper, Stephen R. Pretzel, Rebecca E. Schieve, Laura A. Windham, Gayle C. Daniels, Julie L. Paediatric and Perinatal Epidemiology Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) Pediatrics, Perinatology and Child Health Epidemiology |
| author_sort |
singer, alison b. |
| spelling |
Singer, Alison B. Aylsworth, Arthur S. Cordero, Christina Croen, Lisa A. DiGuiseppi, Carolyn Fallin, M. Daniele Herring, Amy H. Hooper, Stephen R. Pretzel, Rebecca E. Schieve, Laura A. Windham, Gayle C. Daniels, Julie L. 0269-5022 1365-3016 Wiley Pediatrics, Perinatology and Child Health Epidemiology http://dx.doi.org/10.1111/ppe.12404 <jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Prenatal alcohol exposure can affect neurodevelopment, but few studies have examined associations with autism spectrum disorder (<jats:styled-content style="fixed-case">ASD</jats:styled-content>).</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We assessed the association between maternal alcohol use and <jats:styled-content style="fixed-case">ASD</jats:styled-content> in the Study to Explore Early Development, a multi‐site case–control study of children born between September 2003 and August 2006 in the US Regression analyses included 684 children with research clinician‐confirmed <jats:styled-content style="fixed-case">ASD</jats:styled-content>, 869 children with non‐<jats:styled-content style="fixed-case">ASD</jats:styled-content> developmental delays or disorders (<jats:styled-content style="fixed-case">DD</jats:styled-content>s), and 962 controls ascertained from the general population (<jats:styled-content style="fixed-case">POP</jats:styled-content>). Maternal alcohol exposure during each month from 3 months prior to conception until delivery was assessed by self‐report.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Mothers of <jats:styled-content style="fixed-case">POP</jats:styled-content> children were more likely to report any prenatal alcohol use than mothers of children with <jats:styled-content style="fixed-case">ASD</jats:styled-content> or <jats:styled-content style="fixed-case">DD</jats:styled-content>. In trimester one, 21.2% of mothers of <jats:styled-content style="fixed-case">POP</jats:styled-content> children reported alcohol use compared with 18.1% and 18.2% of mothers of children with <jats:styled-content style="fixed-case">ASD</jats:styled-content> or <jats:styled-content style="fixed-case">DD,</jats:styled-content> respectively (adjusted <jats:styled-content style="fixed-case">OR</jats:styled-content> for <jats:styled-content style="fixed-case">ASD</jats:styled-content> vs. <jats:styled-content style="fixed-case">POP</jats:styled-content> 0.8, 95% confidence interval 0.6, 1.1). During preconception and the first month of pregnancy, one to two drinks on average per week was inversely associated with <jats:styled-content style="fixed-case">ASD</jats:styled-content> risk.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>These results do not support an adverse association between low‐level alcohol exposure and <jats:styled-content style="fixed-case">ASD</jats:styled-content>, although these findings were based on retrospective self‐reported alcohol use. Unmeasured confounding or exposure misclassification may explain inverse associations with one to two drinks per week. Pregnant or potentially pregnant women should continue to follow recommendations to avoid alcohol use because of other known effects on infant health and neurodevelopment.</jats:p></jats:sec> Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (<scp>SEED</scp>) Paediatric and Perinatal Epidemiology |
| doi_str_mv |
10.1111/ppe.12404 |
| facet_avail |
Online |
| finc_class_facet |
Medizin |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9wcGUuMTI0MDQ |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9wcGUuMTI0MDQ |
| institution |
DE-Brt1 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 DE-Ch1 DE-L229 DE-D275 DE-Bn3 |
| imprint |
Wiley, 2017 |
| imprint_str_mv |
Wiley, 2017 |
| issn |
0269-5022 1365-3016 |
| issn_str_mv |
0269-5022 1365-3016 |
| language |
English |
| mega_collection |
Wiley (CrossRef) |
| match_str |
singer2017prenatalalcoholexposureinrelationtoautismspectrumdisorderfindingsfromthestudytoexploreearlydevelopmentseed |
| publishDateSort |
2017 |
| publisher |
Wiley |
| recordtype |
ai |
| record_format |
ai |
| series |
Paediatric and Perinatal Epidemiology |
| source_id |
49 |
| title |
Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) |
| title_unstemmed |
Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) |
| title_full |
Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) |
| title_fullStr |
Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) |
| title_full_unstemmed |
Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) |
| title_short |
Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) |
| title_sort |
prenatal alcohol exposure in relation to autism spectrum disorder: findings from the study to explore early development (<scp>seed</scp>) |
| topic |
Pediatrics, Perinatology and Child Health Epidemiology |
| url |
http://dx.doi.org/10.1111/ppe.12404 |
| publishDate |
2017 |
| physical |
573-582 |
| description |
<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Prenatal alcohol exposure can affect neurodevelopment, but few studies have examined associations with autism spectrum disorder (<jats:styled-content style="fixed-case">ASD</jats:styled-content>).</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We assessed the association between maternal alcohol use and <jats:styled-content style="fixed-case">ASD</jats:styled-content> in the Study to Explore Early Development, a multi‐site case–control study of children born between September 2003 and August 2006 in the US Regression analyses included 684 children with research clinician‐confirmed <jats:styled-content style="fixed-case">ASD</jats:styled-content>, 869 children with non‐<jats:styled-content style="fixed-case">ASD</jats:styled-content> developmental delays or disorders (<jats:styled-content style="fixed-case">DD</jats:styled-content>s), and 962 controls ascertained from the general population (<jats:styled-content style="fixed-case">POP</jats:styled-content>). Maternal alcohol exposure during each month from 3 months prior to conception until delivery was assessed by self‐report.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Mothers of <jats:styled-content style="fixed-case">POP</jats:styled-content> children were more likely to report any prenatal alcohol use than mothers of children with <jats:styled-content style="fixed-case">ASD</jats:styled-content> or <jats:styled-content style="fixed-case">DD</jats:styled-content>. In trimester one, 21.2% of mothers of <jats:styled-content style="fixed-case">POP</jats:styled-content> children reported alcohol use compared with 18.1% and 18.2% of mothers of children with <jats:styled-content style="fixed-case">ASD</jats:styled-content> or <jats:styled-content style="fixed-case">DD,</jats:styled-content> respectively (adjusted <jats:styled-content style="fixed-case">OR</jats:styled-content> for <jats:styled-content style="fixed-case">ASD</jats:styled-content> vs. <jats:styled-content style="fixed-case">POP</jats:styled-content> 0.8, 95% confidence interval 0.6, 1.1). During preconception and the first month of pregnancy, one to two drinks on average per week was inversely associated with <jats:styled-content style="fixed-case">ASD</jats:styled-content> risk.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>These results do not support an adverse association between low‐level alcohol exposure and <jats:styled-content style="fixed-case">ASD</jats:styled-content>, although these findings were based on retrospective self‐reported alcohol use. Unmeasured confounding or exposure misclassification may explain inverse associations with one to two drinks per week. Pregnant or potentially pregnant women should continue to follow recommendations to avoid alcohol use because of other known effects on infant health and neurodevelopment.</jats:p></jats:sec> |
| container_issue |
6 |
| container_start_page |
573 |
| container_title |
Paediatric and Perinatal Epidemiology |
| container_volume |
31 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792346969155305484 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T17:47:25.21Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Prenatal+Alcohol+Exposure+in+Relation+to+Autism+Spectrum+Disorder%3A+Findings+from+the+Study+to+Explore+Early+Development+%28SEED%29&rft.date=2017-11-01&genre=article&issn=1365-3016&volume=31&issue=6&spage=573&epage=582&pages=573-582&jtitle=Paediatric+and+Perinatal+Epidemiology&atitle=Prenatal+Alcohol+Exposure+in+Relation+to+Autism+Spectrum+Disorder%3A+Findings+from+the+Study+to+Explore+Early+Development+%28%3Cscp%3ESEED%3C%2Fscp%3E%29&aulast=Daniels&aufirst=Julie+L.&rft_id=info%3Adoi%2F10.1111%2Fppe.12404&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792346969155305484 |
| author | Singer, Alison B., Aylsworth, Arthur S., Cordero, Christina, Croen, Lisa A., DiGuiseppi, Carolyn, Fallin, M. Daniele, Herring, Amy H., Hooper, Stephen R., Pretzel, Rebecca E., Schieve, Laura A., Windham, Gayle C., Daniels, Julie L. |
| author_facet | Singer, Alison B., Aylsworth, Arthur S., Cordero, Christina, Croen, Lisa A., DiGuiseppi, Carolyn, Fallin, M. Daniele, Herring, Amy H., Hooper, Stephen R., Pretzel, Rebecca E., Schieve, Laura A., Windham, Gayle C., Daniels, Julie L., Singer, Alison B., Aylsworth, Arthur S., Cordero, Christina, Croen, Lisa A., DiGuiseppi, Carolyn, Fallin, M. Daniele, Herring, Amy H., Hooper, Stephen R., Pretzel, Rebecca E., Schieve, Laura A., Windham, Gayle C., Daniels, Julie L. |
| author_sort | singer, alison b. |
| container_issue | 6 |
| container_start_page | 573 |
| container_title | Paediatric and Perinatal Epidemiology |
| container_volume | 31 |
| description | <jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Prenatal alcohol exposure can affect neurodevelopment, but few studies have examined associations with autism spectrum disorder (<jats:styled-content style="fixed-case">ASD</jats:styled-content>).</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We assessed the association between maternal alcohol use and <jats:styled-content style="fixed-case">ASD</jats:styled-content> in the Study to Explore Early Development, a multi‐site case–control study of children born between September 2003 and August 2006 in the US Regression analyses included 684 children with research clinician‐confirmed <jats:styled-content style="fixed-case">ASD</jats:styled-content>, 869 children with non‐<jats:styled-content style="fixed-case">ASD</jats:styled-content> developmental delays or disorders (<jats:styled-content style="fixed-case">DD</jats:styled-content>s), and 962 controls ascertained from the general population (<jats:styled-content style="fixed-case">POP</jats:styled-content>). Maternal alcohol exposure during each month from 3 months prior to conception until delivery was assessed by self‐report.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Mothers of <jats:styled-content style="fixed-case">POP</jats:styled-content> children were more likely to report any prenatal alcohol use than mothers of children with <jats:styled-content style="fixed-case">ASD</jats:styled-content> or <jats:styled-content style="fixed-case">DD</jats:styled-content>. In trimester one, 21.2% of mothers of <jats:styled-content style="fixed-case">POP</jats:styled-content> children reported alcohol use compared with 18.1% and 18.2% of mothers of children with <jats:styled-content style="fixed-case">ASD</jats:styled-content> or <jats:styled-content style="fixed-case">DD,</jats:styled-content> respectively (adjusted <jats:styled-content style="fixed-case">OR</jats:styled-content> for <jats:styled-content style="fixed-case">ASD</jats:styled-content> vs. <jats:styled-content style="fixed-case">POP</jats:styled-content> 0.8, 95% confidence interval 0.6, 1.1). During preconception and the first month of pregnancy, one to two drinks on average per week was inversely associated with <jats:styled-content style="fixed-case">ASD</jats:styled-content> risk.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>These results do not support an adverse association between low‐level alcohol exposure and <jats:styled-content style="fixed-case">ASD</jats:styled-content>, although these findings were based on retrospective self‐reported alcohol use. Unmeasured confounding or exposure misclassification may explain inverse associations with one to two drinks per week. Pregnant or potentially pregnant women should continue to follow recommendations to avoid alcohol use because of other known effects on infant health and neurodevelopment.</jats:p></jats:sec> |
| doi_str_mv | 10.1111/ppe.12404 |
| facet_avail | Online |
| finc_class_facet | Medizin |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9wcGUuMTI0MDQ |
| imprint | Wiley, 2017 |
| imprint_str_mv | Wiley, 2017 |
| institution | DE-Brt1, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3 |
| issn | 0269-5022, 1365-3016 |
| issn_str_mv | 0269-5022, 1365-3016 |
| language | English |
| last_indexed | 2024-03-01T17:47:25.21Z |
| match_str | singer2017prenatalalcoholexposureinrelationtoautismspectrumdisorderfindingsfromthestudytoexploreearlydevelopmentseed |
| mega_collection | Wiley (CrossRef) |
| physical | 573-582 |
| publishDate | 2017 |
| publishDateSort | 2017 |
| publisher | Wiley |
| record_format | ai |
| recordtype | ai |
| series | Paediatric and Perinatal Epidemiology |
| source_id | 49 |
| spelling | Singer, Alison B. Aylsworth, Arthur S. Cordero, Christina Croen, Lisa A. DiGuiseppi, Carolyn Fallin, M. Daniele Herring, Amy H. Hooper, Stephen R. Pretzel, Rebecca E. Schieve, Laura A. Windham, Gayle C. Daniels, Julie L. 0269-5022 1365-3016 Wiley Pediatrics, Perinatology and Child Health Epidemiology http://dx.doi.org/10.1111/ppe.12404 <jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Prenatal alcohol exposure can affect neurodevelopment, but few studies have examined associations with autism spectrum disorder (<jats:styled-content style="fixed-case">ASD</jats:styled-content>).</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We assessed the association between maternal alcohol use and <jats:styled-content style="fixed-case">ASD</jats:styled-content> in the Study to Explore Early Development, a multi‐site case–control study of children born between September 2003 and August 2006 in the US Regression analyses included 684 children with research clinician‐confirmed <jats:styled-content style="fixed-case">ASD</jats:styled-content>, 869 children with non‐<jats:styled-content style="fixed-case">ASD</jats:styled-content> developmental delays or disorders (<jats:styled-content style="fixed-case">DD</jats:styled-content>s), and 962 controls ascertained from the general population (<jats:styled-content style="fixed-case">POP</jats:styled-content>). Maternal alcohol exposure during each month from 3 months prior to conception until delivery was assessed by self‐report.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Mothers of <jats:styled-content style="fixed-case">POP</jats:styled-content> children were more likely to report any prenatal alcohol use than mothers of children with <jats:styled-content style="fixed-case">ASD</jats:styled-content> or <jats:styled-content style="fixed-case">DD</jats:styled-content>. In trimester one, 21.2% of mothers of <jats:styled-content style="fixed-case">POP</jats:styled-content> children reported alcohol use compared with 18.1% and 18.2% of mothers of children with <jats:styled-content style="fixed-case">ASD</jats:styled-content> or <jats:styled-content style="fixed-case">DD,</jats:styled-content> respectively (adjusted <jats:styled-content style="fixed-case">OR</jats:styled-content> for <jats:styled-content style="fixed-case">ASD</jats:styled-content> vs. <jats:styled-content style="fixed-case">POP</jats:styled-content> 0.8, 95% confidence interval 0.6, 1.1). During preconception and the first month of pregnancy, one to two drinks on average per week was inversely associated with <jats:styled-content style="fixed-case">ASD</jats:styled-content> risk.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>These results do not support an adverse association between low‐level alcohol exposure and <jats:styled-content style="fixed-case">ASD</jats:styled-content>, although these findings were based on retrospective self‐reported alcohol use. Unmeasured confounding or exposure misclassification may explain inverse associations with one to two drinks per week. Pregnant or potentially pregnant women should continue to follow recommendations to avoid alcohol use because of other known effects on infant health and neurodevelopment.</jats:p></jats:sec> Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (<scp>SEED</scp>) Paediatric and Perinatal Epidemiology |
| spellingShingle | Singer, Alison B., Aylsworth, Arthur S., Cordero, Christina, Croen, Lisa A., DiGuiseppi, Carolyn, Fallin, M. Daniele, Herring, Amy H., Hooper, Stephen R., Pretzel, Rebecca E., Schieve, Laura A., Windham, Gayle C., Daniels, Julie L., Paediatric and Perinatal Epidemiology, Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED), Pediatrics, Perinatology and Child Health, Epidemiology |
| title | Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) |
| title_full | Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) |
| title_fullStr | Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) |
| title_full_unstemmed | Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) |
| title_short | Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) |
| title_sort | prenatal alcohol exposure in relation to autism spectrum disorder: findings from the study to explore early development (<scp>seed</scp>) |
| title_unstemmed | Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED) |
| topic | Pediatrics, Perinatology and Child Health, Epidemiology |
| url | http://dx.doi.org/10.1111/ppe.12404 |