Eintrag weiter verarbeiten
A fresh look at IBS—opportunities for systems medicine approaches
Gespeichert in:
| Zeitschriftentitel: | Neurogastroenterology & Motility |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , , , , |
| In: | Neurogastroenterology & Motility, 29, 2017, 3 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Albusoda, A. Barki, N. Herregods, T. Kamphuis, J. B. J. Karunaratne, T. B. Lazarou, M. Lee, I. Mazurak, N. Perna, E. Polster, A. Pribic, T. Uhlig, F. Wang, H. Enck, P. Albusoda, A. Barki, N. Herregods, T. Kamphuis, J. B. J. Karunaratne, T. B. Lazarou, M. Lee, I. Mazurak, N. Perna, E. Polster, A. Pribic, T. Uhlig, F. Wang, H. Enck, P. |
|---|---|
| author |
Albusoda, A. Barki, N. Herregods, T. Kamphuis, J. B. J. Karunaratne, T. B. Lazarou, M. Lee, I. Mazurak, N. Perna, E. Polster, A. Pribic, T. Uhlig, F. Wang, H. Enck, P. |
| spellingShingle |
Albusoda, A. Barki, N. Herregods, T. Kamphuis, J. B. J. Karunaratne, T. B. Lazarou, M. Lee, I. Mazurak, N. Perna, E. Polster, A. Pribic, T. Uhlig, F. Wang, H. Enck, P. Neurogastroenterology & Motility A fresh look at IBS—opportunities for systems medicine approaches Gastroenterology Endocrine and Autonomic Systems Physiology |
| author_sort |
albusoda, a. |
| spelling |
Albusoda, A. Barki, N. Herregods, T. Kamphuis, J. B. J. Karunaratne, T. B. Lazarou, M. Lee, I. Mazurak, N. Perna, E. Polster, A. Pribic, T. Uhlig, F. Wang, H. Enck, P. 1350-1925 1365-2982 Wiley Gastroenterology Endocrine and Autonomic Systems Physiology http://dx.doi.org/10.1111/nmo.12989 <jats:title>Abstract</jats:title><jats:p>Neuro<jats:styled-content style="fixed-case">GUT</jats:styled-content> is a <jats:styled-content style="fixed-case">EU</jats:styled-content>‐funded initial training network (<jats:styled-content style="fixed-case">ITN</jats:styled-content>) of 14 research projects in neurogastroenterology that have employed an equal number of early‐stage researchers. Neurogut trainees have—among other activities—attended an international conference on irritable bowel syndrome (<jats:styled-content style="fixed-case">IBS</jats:styled-content>) in Bologna in 2016 and were asked to critically review and evaluate the current knowledge on <jats:styled-content style="fixed-case">IBS</jats:styled-content> for their respective research activities, and to state what they were missing. Most appreciated were the topics brain imaging of gut activity, the role of the gut microbiota, the pharmacology of gut functions, the <jats:styled-content style="fixed-case">IBS</jats:styled-content>‐<jats:styled-content style="fixed-case">IBD</jats:styled-content> interrelation, the new Rome IV criteria, the role of gas, and the placebo response in functional disorders. Missed were more detailed coverage of high‐resolution manometry, functional brain imaging, advanced “systems medicine” approaches and bioinformatics technology, better sub‐classification of <jats:styled-content style="fixed-case">IBS</jats:styled-content> patients, and the development of disease biomarkers, extended at the molecular (genetic/epigenetic, proteonomic) level. They summarize that despite excellent specialized research, there is a gap open that should be filled with systems medicine. For this, it would be necessary that medical research learns even more from the data sciences and other basic disciplines, for example, information technology and system biology, and also welcomes a change in paradigm that enhances open sharing of data, information, and resources.</jats:p> A fresh look at <scp>IBS</scp>—opportunities for systems medicine approaches Neurogastroenterology & Motility |
| doi_str_mv |
10.1111/nmo.12989 |
| facet_avail |
Online |
| finc_class_facet |
Medizin Biologie |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9ubW8uMTI5ODk |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9ubW8uMTI5ODk |
| institution |
DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 |
| imprint |
Wiley, 2017 |
| imprint_str_mv |
Wiley, 2017 |
| issn |
1350-1925 1365-2982 |
| issn_str_mv |
1350-1925 1365-2982 |
| language |
English |
| mega_collection |
Wiley (CrossRef) |
| match_str |
albusoda2017afreshlookatibsopportunitiesforsystemsmedicineapproaches |
| publishDateSort |
2017 |
| publisher |
Wiley |
| recordtype |
ai |
| record_format |
ai |
| series |
Neurogastroenterology & Motility |
| source_id |
49 |
| title |
A fresh look at IBS—opportunities for systems medicine approaches |
| title_unstemmed |
A fresh look at IBS—opportunities for systems medicine approaches |
| title_full |
A fresh look at IBS—opportunities for systems medicine approaches |
| title_fullStr |
A fresh look at IBS—opportunities for systems medicine approaches |
| title_full_unstemmed |
A fresh look at IBS—opportunities for systems medicine approaches |
| title_short |
A fresh look at IBS—opportunities for systems medicine approaches |
| title_sort |
a fresh look at <scp>ibs</scp>—opportunities for systems medicine approaches |
| topic |
Gastroenterology Endocrine and Autonomic Systems Physiology |
| url |
http://dx.doi.org/10.1111/nmo.12989 |
| publishDate |
2017 |
| physical |
|
| description |
<jats:title>Abstract</jats:title><jats:p>Neuro<jats:styled-content style="fixed-case">GUT</jats:styled-content> is a <jats:styled-content style="fixed-case">EU</jats:styled-content>‐funded initial training network (<jats:styled-content style="fixed-case">ITN</jats:styled-content>) of 14 research projects in neurogastroenterology that have employed an equal number of early‐stage researchers. Neurogut trainees have—among other activities—attended an international conference on irritable bowel syndrome (<jats:styled-content style="fixed-case">IBS</jats:styled-content>) in Bologna in 2016 and were asked to critically review and evaluate the current knowledge on <jats:styled-content style="fixed-case">IBS</jats:styled-content> for their respective research activities, and to state what they were missing. Most appreciated were the topics brain imaging of gut activity, the role of the gut microbiota, the pharmacology of gut functions, the <jats:styled-content style="fixed-case">IBS</jats:styled-content>‐<jats:styled-content style="fixed-case">IBD</jats:styled-content> interrelation, the new Rome IV criteria, the role of gas, and the placebo response in functional disorders. Missed were more detailed coverage of high‐resolution manometry, functional brain imaging, advanced “systems medicine” approaches and bioinformatics technology, better sub‐classification of <jats:styled-content style="fixed-case">IBS</jats:styled-content> patients, and the development of disease biomarkers, extended at the molecular (genetic/epigenetic, proteonomic) level. They summarize that despite excellent specialized research, there is a gap open that should be filled with systems medicine. For this, it would be necessary that medical research learns even more from the data sciences and other basic disciplines, for example, information technology and system biology, and also welcomes a change in paradigm that enhances open sharing of data, information, and resources.</jats:p> |
| container_issue |
3 |
| container_start_page |
0 |
| container_title |
Neurogastroenterology & Motility |
| container_volume |
29 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792335098572439552 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T14:39:09.058Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=A+fresh+look+at+IBS%E2%80%94opportunities+for+systems+medicine+approaches&rft.date=2017-03-01&genre=article&issn=1365-2982&volume=29&issue=3&jtitle=Neurogastroenterology+%26+Motility&atitle=A+fresh+look+at+%3Cscp%3EIBS%3C%2Fscp%3E%E2%80%94opportunities+for+systems+medicine+approaches&aulast=Enck&aufirst=P.&rft_id=info%3Adoi%2F10.1111%2Fnmo.12989&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792335098572439552 |
| author | Albusoda, A., Barki, N., Herregods, T., Kamphuis, J. B. J., Karunaratne, T. B., Lazarou, M., Lee, I., Mazurak, N., Perna, E., Polster, A., Pribic, T., Uhlig, F., Wang, H., Enck, P. |
| author_facet | Albusoda, A., Barki, N., Herregods, T., Kamphuis, J. B. J., Karunaratne, T. B., Lazarou, M., Lee, I., Mazurak, N., Perna, E., Polster, A., Pribic, T., Uhlig, F., Wang, H., Enck, P., Albusoda, A., Barki, N., Herregods, T., Kamphuis, J. B. J., Karunaratne, T. B., Lazarou, M., Lee, I., Mazurak, N., Perna, E., Polster, A., Pribic, T., Uhlig, F., Wang, H., Enck, P. |
| author_sort | albusoda, a. |
| container_issue | 3 |
| container_start_page | 0 |
| container_title | Neurogastroenterology & Motility |
| container_volume | 29 |
| description | <jats:title>Abstract</jats:title><jats:p>Neuro<jats:styled-content style="fixed-case">GUT</jats:styled-content> is a <jats:styled-content style="fixed-case">EU</jats:styled-content>‐funded initial training network (<jats:styled-content style="fixed-case">ITN</jats:styled-content>) of 14 research projects in neurogastroenterology that have employed an equal number of early‐stage researchers. Neurogut trainees have—among other activities—attended an international conference on irritable bowel syndrome (<jats:styled-content style="fixed-case">IBS</jats:styled-content>) in Bologna in 2016 and were asked to critically review and evaluate the current knowledge on <jats:styled-content style="fixed-case">IBS</jats:styled-content> for their respective research activities, and to state what they were missing. Most appreciated were the topics brain imaging of gut activity, the role of the gut microbiota, the pharmacology of gut functions, the <jats:styled-content style="fixed-case">IBS</jats:styled-content>‐<jats:styled-content style="fixed-case">IBD</jats:styled-content> interrelation, the new Rome IV criteria, the role of gas, and the placebo response in functional disorders. Missed were more detailed coverage of high‐resolution manometry, functional brain imaging, advanced “systems medicine” approaches and bioinformatics technology, better sub‐classification of <jats:styled-content style="fixed-case">IBS</jats:styled-content> patients, and the development of disease biomarkers, extended at the molecular (genetic/epigenetic, proteonomic) level. They summarize that despite excellent specialized research, there is a gap open that should be filled with systems medicine. For this, it would be necessary that medical research learns even more from the data sciences and other basic disciplines, for example, information technology and system biology, and also welcomes a change in paradigm that enhances open sharing of data, information, and resources.</jats:p> |
| doi_str_mv | 10.1111/nmo.12989 |
| facet_avail | Online |
| finc_class_facet | Medizin, Biologie |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTExMS9ubW8uMTI5ODk |
| imprint | Wiley, 2017 |
| imprint_str_mv | Wiley, 2017 |
| institution | DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14 |
| issn | 1350-1925, 1365-2982 |
| issn_str_mv | 1350-1925, 1365-2982 |
| language | English |
| last_indexed | 2024-03-01T14:39:09.058Z |
| match_str | albusoda2017afreshlookatibsopportunitiesforsystemsmedicineapproaches |
| mega_collection | Wiley (CrossRef) |
| physical | |
| publishDate | 2017 |
| publishDateSort | 2017 |
| publisher | Wiley |
| record_format | ai |
| recordtype | ai |
| series | Neurogastroenterology & Motility |
| source_id | 49 |
| spelling | Albusoda, A. Barki, N. Herregods, T. Kamphuis, J. B. J. Karunaratne, T. B. Lazarou, M. Lee, I. Mazurak, N. Perna, E. Polster, A. Pribic, T. Uhlig, F. Wang, H. Enck, P. 1350-1925 1365-2982 Wiley Gastroenterology Endocrine and Autonomic Systems Physiology http://dx.doi.org/10.1111/nmo.12989 <jats:title>Abstract</jats:title><jats:p>Neuro<jats:styled-content style="fixed-case">GUT</jats:styled-content> is a <jats:styled-content style="fixed-case">EU</jats:styled-content>‐funded initial training network (<jats:styled-content style="fixed-case">ITN</jats:styled-content>) of 14 research projects in neurogastroenterology that have employed an equal number of early‐stage researchers. Neurogut trainees have—among other activities—attended an international conference on irritable bowel syndrome (<jats:styled-content style="fixed-case">IBS</jats:styled-content>) in Bologna in 2016 and were asked to critically review and evaluate the current knowledge on <jats:styled-content style="fixed-case">IBS</jats:styled-content> for their respective research activities, and to state what they were missing. Most appreciated were the topics brain imaging of gut activity, the role of the gut microbiota, the pharmacology of gut functions, the <jats:styled-content style="fixed-case">IBS</jats:styled-content>‐<jats:styled-content style="fixed-case">IBD</jats:styled-content> interrelation, the new Rome IV criteria, the role of gas, and the placebo response in functional disorders. Missed were more detailed coverage of high‐resolution manometry, functional brain imaging, advanced “systems medicine” approaches and bioinformatics technology, better sub‐classification of <jats:styled-content style="fixed-case">IBS</jats:styled-content> patients, and the development of disease biomarkers, extended at the molecular (genetic/epigenetic, proteonomic) level. They summarize that despite excellent specialized research, there is a gap open that should be filled with systems medicine. For this, it would be necessary that medical research learns even more from the data sciences and other basic disciplines, for example, information technology and system biology, and also welcomes a change in paradigm that enhances open sharing of data, information, and resources.</jats:p> A fresh look at <scp>IBS</scp>—opportunities for systems medicine approaches Neurogastroenterology & Motility |
| spellingShingle | Albusoda, A., Barki, N., Herregods, T., Kamphuis, J. B. J., Karunaratne, T. B., Lazarou, M., Lee, I., Mazurak, N., Perna, E., Polster, A., Pribic, T., Uhlig, F., Wang, H., Enck, P., Neurogastroenterology & Motility, A fresh look at IBS—opportunities for systems medicine approaches, Gastroenterology, Endocrine and Autonomic Systems, Physiology |
| title | A fresh look at IBS—opportunities for systems medicine approaches |
| title_full | A fresh look at IBS—opportunities for systems medicine approaches |
| title_fullStr | A fresh look at IBS—opportunities for systems medicine approaches |
| title_full_unstemmed | A fresh look at IBS—opportunities for systems medicine approaches |
| title_short | A fresh look at IBS—opportunities for systems medicine approaches |
| title_sort | a fresh look at <scp>ibs</scp>—opportunities for systems medicine approaches |
| title_unstemmed | A fresh look at IBS—opportunities for systems medicine approaches |
| topic | Gastroenterology, Endocrine and Autonomic Systems, Physiology |
| url | http://dx.doi.org/10.1111/nmo.12989 |