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Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle
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| Zeitschriftentitel: | Journal of Veterinary Internal Medicine |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Journal of Veterinary Internal Medicine, 29, 2015, 1, S. 388-394 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Yildirim, E. Karapinar, T. Hayirli, A. Yildirim, E. Karapinar, T. Hayirli, A. |
|---|---|
| author |
Yildirim, E. Karapinar, T. Hayirli, A. |
| spellingShingle |
Yildirim, E. Karapinar, T. Hayirli, A. Journal of Veterinary Internal Medicine Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle General Veterinary |
| author_sort |
yildirim, e. |
| spelling |
Yildirim, E. Karapinar, T. Hayirli, A. 0891-6640 1939-1676 Wiley General Veterinary http://dx.doi.org/10.1111/jvim.12526 <jats:sec><jats:title>Background</jats:title><jats:p>Rapid determination of blood electrolyte concentrations can help determine electrolyte status and delivery of effective volume of electrolyte solutions in field conditions.</jats:p></jats:sec><jats:sec><jats:title>Objective</jats:title><jats:p>To evaluate reliability of the i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content>, a point‐of‐care (<jats:styled-content style="fixed-case">POC</jats:styled-content>) device, in measuring blood K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> concentrations in cattle.</jats:p></jats:sec><jats:sec><jats:title>Animals</jats:title><jats:p>Ninety‐eight cattle with various diseases.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>In this prospective study, blood samples collected from the jugular vein were processed for determination of K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> concentrations in blood and plasma using the i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> and auto‐analyzer (Cobas C501), respectively. Blood and plasma electrolyte data were subjected to student <jats:italic>t</jats:italic>‐test for comparison, the concordance analysis for agreement, accuracy, and precision, the Passing‐Bablok regression and the Bland‐Altman plot for reliability, and receiver operating characteristics curves for sensitivity (Se) and specificity (Sp).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Plasma concentrations of K<jats:sup>+</jats:sup> (4.39 versus 4.2 mmol/L; <jats:italic>P </jats:italic><<jats:italic> </jats:italic>.0001) and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> (100.30 versus 99.4 mmol/L; <jats:italic>P </jats:italic><<jats:italic> </jats:italic>.04) were greater than their concentrations in blood. Plasma and blood Na<jats:sup>+</jats:sup> concentrations were similar (136.95 versus 136.8 mmol/L). The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> results were highly correlated with the Cobas C501 results (<jats:italic>r </jats:italic>=<jats:italic> </jats:italic>0.970, 0.922, and 0.866 for K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup>, respectively). Regression equations fitting blood (<jats:italic>Y</jats:italic>) and plasma (<jats:italic>X</jats:italic>) concentration did not deviate from the identity line for K<jats:sup>+</jats:sup> (<jats:italic>Y</jats:italic> = −0.10 + 0.98 × <jats:italic>X</jats:italic>), Na<jats:sup>+</jats:sup> (<jats:italic>Y</jats:italic> = <jats:italic>X</jats:italic>), and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> (<jats:italic>Y</jats:italic> = 3.04 + 0.96 × <jats:italic>X</jats:italic>). The mean bias (blood concentration ‐ plasma concentration) was −0.20 for K<jats:sup>+</jats:sup> (<jats:italic>P </jats:italic>=<jats:italic> </jats:italic>.03), −0.16 for Na<jats:sup>+</jats:sup> (<jats:italic>P </jats:italic>=<jats:italic> </jats:italic>.12), and −0.87 for <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> (<jats:italic>P </jats:italic>=<jats:italic> </jats:italic>.93). The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> had 76–100% Se and 87.7–100% Sp for assessing electrolyte statuses.</jats:p></jats:sec><jats:sec><jats:title>Conclusions and Clinical Importance</jats:title><jats:p>The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> yielded results that were in agreement with the auto‐analyzer, with negligible biases in measurement of plasma K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> concentrations. The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> is a reliable <jats:styled-content style="fixed-case">POC</jats:styled-content> device and can be used in field condition to assess electrolyte status in cattle.</jats:p></jats:sec> Reliability of the i‐<scp>STAT</scp> for the determination of blood electrolyte (K<sup>+</sup>, Na<sup>+</sup>, and <scp>CI</scp><sup>−</sup>) concentrations in cattle Journal of Veterinary Internal Medicine |
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10.1111/jvim.12526 |
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Online Free |
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ElectronicArticle |
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DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-D161 DE-Zwi2 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 |
| imprint |
Wiley, 2015 |
| imprint_str_mv |
Wiley, 2015 |
| issn |
0891-6640 1939-1676 |
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0891-6640 1939-1676 |
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English |
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Wiley (CrossRef) |
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yildirim2015reliabilityoftheistatforthedeterminationofbloodelectrolyteknaandciconcentrationsincattle |
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2015 |
| publisher |
Wiley |
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ai |
| series |
Journal of Veterinary Internal Medicine |
| source_id |
49 |
| title |
Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle |
| title_unstemmed |
Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle |
| title_full |
Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle |
| title_fullStr |
Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle |
| title_full_unstemmed |
Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle |
| title_short |
Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle |
| title_sort |
reliability of the i‐<scp>stat</scp> for the determination of blood electrolyte (k<sup>+</sup>, na<sup>+</sup>, and <scp>ci</scp><sup>−</sup>) concentrations in cattle |
| topic |
General Veterinary |
| url |
http://dx.doi.org/10.1111/jvim.12526 |
| publishDate |
2015 |
| physical |
388-394 |
| description |
<jats:sec><jats:title>Background</jats:title><jats:p>Rapid determination of blood electrolyte concentrations can help determine electrolyte status and delivery of effective volume of electrolyte solutions in field conditions.</jats:p></jats:sec><jats:sec><jats:title>Objective</jats:title><jats:p>To evaluate reliability of the i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content>, a point‐of‐care (<jats:styled-content style="fixed-case">POC</jats:styled-content>) device, in measuring blood K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> concentrations in cattle.</jats:p></jats:sec><jats:sec><jats:title>Animals</jats:title><jats:p>Ninety‐eight cattle with various diseases.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>In this prospective study, blood samples collected from the jugular vein were processed for determination of K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> concentrations in blood and plasma using the i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> and auto‐analyzer (Cobas C501), respectively. Blood and plasma electrolyte data were subjected to student <jats:italic>t</jats:italic>‐test for comparison, the concordance analysis for agreement, accuracy, and precision, the Passing‐Bablok regression and the Bland‐Altman plot for reliability, and receiver operating characteristics curves for sensitivity (Se) and specificity (Sp).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Plasma concentrations of K<jats:sup>+</jats:sup> (4.39 versus 4.2 mmol/L; <jats:italic>P </jats:italic><<jats:italic> </jats:italic>.0001) and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> (100.30 versus 99.4 mmol/L; <jats:italic>P </jats:italic><<jats:italic> </jats:italic>.04) were greater than their concentrations in blood. Plasma and blood Na<jats:sup>+</jats:sup> concentrations were similar (136.95 versus 136.8 mmol/L). The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> results were highly correlated with the Cobas C501 results (<jats:italic>r </jats:italic>=<jats:italic> </jats:italic>0.970, 0.922, and 0.866 for K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup>, respectively). Regression equations fitting blood (<jats:italic>Y</jats:italic>) and plasma (<jats:italic>X</jats:italic>) concentration did not deviate from the identity line for K<jats:sup>+</jats:sup> (<jats:italic>Y</jats:italic> = −0.10 + 0.98 × <jats:italic>X</jats:italic>), Na<jats:sup>+</jats:sup> (<jats:italic>Y</jats:italic> = <jats:italic>X</jats:italic>), and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> (<jats:italic>Y</jats:italic> = 3.04 + 0.96 × <jats:italic>X</jats:italic>). The mean bias (blood concentration ‐ plasma concentration) was −0.20 for K<jats:sup>+</jats:sup> (<jats:italic>P </jats:italic>=<jats:italic> </jats:italic>.03), −0.16 for Na<jats:sup>+</jats:sup> (<jats:italic>P </jats:italic>=<jats:italic> </jats:italic>.12), and −0.87 for <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> (<jats:italic>P </jats:italic>=<jats:italic> </jats:italic>.93). The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> had 76–100% Se and 87.7–100% Sp for assessing electrolyte statuses.</jats:p></jats:sec><jats:sec><jats:title>Conclusions and Clinical Importance</jats:title><jats:p>The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> yielded results that were in agreement with the auto‐analyzer, with negligible biases in measurement of plasma K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> concentrations. The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> is a reliable <jats:styled-content style="fixed-case">POC</jats:styled-content> device and can be used in field condition to assess electrolyte status in cattle.</jats:p></jats:sec> |
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| author | Yildirim, E., Karapinar, T., Hayirli, A. |
| author_facet | Yildirim, E., Karapinar, T., Hayirli, A., Yildirim, E., Karapinar, T., Hayirli, A. |
| author_sort | yildirim, e. |
| container_issue | 1 |
| container_start_page | 388 |
| container_title | Journal of Veterinary Internal Medicine |
| container_volume | 29 |
| description | <jats:sec><jats:title>Background</jats:title><jats:p>Rapid determination of blood electrolyte concentrations can help determine electrolyte status and delivery of effective volume of electrolyte solutions in field conditions.</jats:p></jats:sec><jats:sec><jats:title>Objective</jats:title><jats:p>To evaluate reliability of the i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content>, a point‐of‐care (<jats:styled-content style="fixed-case">POC</jats:styled-content>) device, in measuring blood K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> concentrations in cattle.</jats:p></jats:sec><jats:sec><jats:title>Animals</jats:title><jats:p>Ninety‐eight cattle with various diseases.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>In this prospective study, blood samples collected from the jugular vein were processed for determination of K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> concentrations in blood and plasma using the i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> and auto‐analyzer (Cobas C501), respectively. Blood and plasma electrolyte data were subjected to student <jats:italic>t</jats:italic>‐test for comparison, the concordance analysis for agreement, accuracy, and precision, the Passing‐Bablok regression and the Bland‐Altman plot for reliability, and receiver operating characteristics curves for sensitivity (Se) and specificity (Sp).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Plasma concentrations of K<jats:sup>+</jats:sup> (4.39 versus 4.2 mmol/L; <jats:italic>P </jats:italic><<jats:italic> </jats:italic>.0001) and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> (100.30 versus 99.4 mmol/L; <jats:italic>P </jats:italic><<jats:italic> </jats:italic>.04) were greater than their concentrations in blood. Plasma and blood Na<jats:sup>+</jats:sup> concentrations were similar (136.95 versus 136.8 mmol/L). The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> results were highly correlated with the Cobas C501 results (<jats:italic>r </jats:italic>=<jats:italic> </jats:italic>0.970, 0.922, and 0.866 for K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup>, respectively). Regression equations fitting blood (<jats:italic>Y</jats:italic>) and plasma (<jats:italic>X</jats:italic>) concentration did not deviate from the identity line for K<jats:sup>+</jats:sup> (<jats:italic>Y</jats:italic> = −0.10 + 0.98 × <jats:italic>X</jats:italic>), Na<jats:sup>+</jats:sup> (<jats:italic>Y</jats:italic> = <jats:italic>X</jats:italic>), and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> (<jats:italic>Y</jats:italic> = 3.04 + 0.96 × <jats:italic>X</jats:italic>). The mean bias (blood concentration ‐ plasma concentration) was −0.20 for K<jats:sup>+</jats:sup> (<jats:italic>P </jats:italic>=<jats:italic> </jats:italic>.03), −0.16 for Na<jats:sup>+</jats:sup> (<jats:italic>P </jats:italic>=<jats:italic> </jats:italic>.12), and −0.87 for <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> (<jats:italic>P </jats:italic>=<jats:italic> </jats:italic>.93). The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> had 76–100% Se and 87.7–100% Sp for assessing electrolyte statuses.</jats:p></jats:sec><jats:sec><jats:title>Conclusions and Clinical Importance</jats:title><jats:p>The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> yielded results that were in agreement with the auto‐analyzer, with negligible biases in measurement of plasma K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> concentrations. The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> is a reliable <jats:styled-content style="fixed-case">POC</jats:styled-content> device and can be used in field condition to assess electrolyte status in cattle.</jats:p></jats:sec> |
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| series | Journal of Veterinary Internal Medicine |
| source_id | 49 |
| spelling | Yildirim, E. Karapinar, T. Hayirli, A. 0891-6640 1939-1676 Wiley General Veterinary http://dx.doi.org/10.1111/jvim.12526 <jats:sec><jats:title>Background</jats:title><jats:p>Rapid determination of blood electrolyte concentrations can help determine electrolyte status and delivery of effective volume of electrolyte solutions in field conditions.</jats:p></jats:sec><jats:sec><jats:title>Objective</jats:title><jats:p>To evaluate reliability of the i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content>, a point‐of‐care (<jats:styled-content style="fixed-case">POC</jats:styled-content>) device, in measuring blood K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> concentrations in cattle.</jats:p></jats:sec><jats:sec><jats:title>Animals</jats:title><jats:p>Ninety‐eight cattle with various diseases.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>In this prospective study, blood samples collected from the jugular vein were processed for determination of K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> concentrations in blood and plasma using the i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> and auto‐analyzer (Cobas C501), respectively. Blood and plasma electrolyte data were subjected to student <jats:italic>t</jats:italic>‐test for comparison, the concordance analysis for agreement, accuracy, and precision, the Passing‐Bablok regression and the Bland‐Altman plot for reliability, and receiver operating characteristics curves for sensitivity (Se) and specificity (Sp).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Plasma concentrations of K<jats:sup>+</jats:sup> (4.39 versus 4.2 mmol/L; <jats:italic>P </jats:italic><<jats:italic> </jats:italic>.0001) and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> (100.30 versus 99.4 mmol/L; <jats:italic>P </jats:italic><<jats:italic> </jats:italic>.04) were greater than their concentrations in blood. Plasma and blood Na<jats:sup>+</jats:sup> concentrations were similar (136.95 versus 136.8 mmol/L). The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> results were highly correlated with the Cobas C501 results (<jats:italic>r </jats:italic>=<jats:italic> </jats:italic>0.970, 0.922, and 0.866 for K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup>, respectively). Regression equations fitting blood (<jats:italic>Y</jats:italic>) and plasma (<jats:italic>X</jats:italic>) concentration did not deviate from the identity line for K<jats:sup>+</jats:sup> (<jats:italic>Y</jats:italic> = −0.10 + 0.98 × <jats:italic>X</jats:italic>), Na<jats:sup>+</jats:sup> (<jats:italic>Y</jats:italic> = <jats:italic>X</jats:italic>), and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> (<jats:italic>Y</jats:italic> = 3.04 + 0.96 × <jats:italic>X</jats:italic>). The mean bias (blood concentration ‐ plasma concentration) was −0.20 for K<jats:sup>+</jats:sup> (<jats:italic>P </jats:italic>=<jats:italic> </jats:italic>.03), −0.16 for Na<jats:sup>+</jats:sup> (<jats:italic>P </jats:italic>=<jats:italic> </jats:italic>.12), and −0.87 for <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> (<jats:italic>P </jats:italic>=<jats:italic> </jats:italic>.93). The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> had 76–100% Se and 87.7–100% Sp for assessing electrolyte statuses.</jats:p></jats:sec><jats:sec><jats:title>Conclusions and Clinical Importance</jats:title><jats:p>The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> yielded results that were in agreement with the auto‐analyzer, with negligible biases in measurement of plasma K<jats:sup>+</jats:sup>, Na<jats:sup>+</jats:sup>, and <jats:styled-content style="fixed-case">CI</jats:styled-content><jats:sup>−</jats:sup> concentrations. The i‐<jats:styled-content style="fixed-case">STAT</jats:styled-content> is a reliable <jats:styled-content style="fixed-case">POC</jats:styled-content> device and can be used in field condition to assess electrolyte status in cattle.</jats:p></jats:sec> Reliability of the i‐<scp>STAT</scp> for the determination of blood electrolyte (K<sup>+</sup>, Na<sup>+</sup>, and <scp>CI</scp><sup>−</sup>) concentrations in cattle Journal of Veterinary Internal Medicine |
| spellingShingle | Yildirim, E., Karapinar, T., Hayirli, A., Journal of Veterinary Internal Medicine, Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle, General Veterinary |
| title | Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle |
| title_full | Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle |
| title_fullStr | Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle |
| title_full_unstemmed | Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle |
| title_short | Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle |
| title_sort | reliability of the i‐<scp>stat</scp> for the determination of blood electrolyte (k<sup>+</sup>, na<sup>+</sup>, and <scp>ci</scp><sup>−</sup>) concentrations in cattle |
| title_unstemmed | Reliability of the i‐STAT for the determination of blood electrolyte (K+, Na+, and CI−) concentrations in cattle |
| topic | General Veterinary |
| url | http://dx.doi.org/10.1111/jvim.12526 |