author_facet Usami, Tomoka
Yokoyama, Maki
Ueno, Megumi
Iwama, Noriyuki
Sagawa, Norimasa
Kawano, Reo
Waguri, Masako
Sameshima, Hiroshi
Hiramatsu, Yuji
Sugiyama, Takashi
Usami, Tomoka
Yokoyama, Maki
Ueno, Megumi
Iwama, Noriyuki
Sagawa, Norimasa
Kawano, Reo
Waguri, Masako
Sameshima, Hiroshi
Hiramatsu, Yuji
Sugiyama, Takashi
author Usami, Tomoka
Yokoyama, Maki
Ueno, Megumi
Iwama, Noriyuki
Sagawa, Norimasa
Kawano, Reo
Waguri, Masako
Sameshima, Hiroshi
Hiramatsu, Yuji
Sugiyama, Takashi
spellingShingle Usami, Tomoka
Yokoyama, Maki
Ueno, Megumi
Iwama, Noriyuki
Sagawa, Norimasa
Kawano, Reo
Waguri, Masako
Sameshima, Hiroshi
Hiramatsu, Yuji
Sugiyama, Takashi
Journal of Diabetes Investigation
Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
General Medicine
Endocrinology, Diabetes and Metabolism
Internal Medicine
author_sort usami, tomoka
spelling Usami, Tomoka Yokoyama, Maki Ueno, Megumi Iwama, Noriyuki Sagawa, Norimasa Kawano, Reo Waguri, Masako Sameshima, Hiroshi Hiramatsu, Yuji Sugiyama, Takashi 2040-1116 2040-1124 Wiley General Medicine Endocrinology, Diabetes and Metabolism Internal Medicine http://dx.doi.org/10.1111/jdi.13101 <jats:title>Abstract</jats:title><jats:sec><jats:title>Aims/Introduction</jats:title><jats:p>To compare pregnancy outcomes between women with gestational diabetes mellitus (GDM) diagnosed early and late in pregnancy in Japan.</jats:p></jats:sec><jats:sec><jats:title>Materials and Methods</jats:title><jats:p>We examined women diagnosed with GDM in this multi‐institutional retrospective study. Women were divided into two groups by gestational age at diagnosis: &lt;24 weeks of gestation (early group, 14.4 ± 4.2 weeks) and ≥24 weeks of gestation (late group, 29.6 ± 3.4 weeks). Dietary counseling with self‐monitoring of blood glucose with or without insulin therapy was initiated for both groups. Pregnancy outcomes were compared between the groups.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Data from 600 early and 881 late group participants from 40 institutions were included. Although pre‐pregnancy body mass index was higher in the early group than in the late group, gestational weight gain was lower in the early group. Hypertensive disorders of pregnancy and cesarean section were more prevalent in the early than in the late group (9.3% vs 4.8%, <jats:italic>P</jats:italic> &lt; 0.001; 34.2% vs 32.0%, <jats:italic>P</jats:italic> &lt; 0.001, respectively). The prevalence of large‐for‐gestational‐age infants was higher in the late than in the early group (24.6% vs 19.7%, respectively, <jats:italic>P</jats:italic> = 0.025). There was no significant difference in other neonatal adverse outcomes between the groups. Multiple logistic regression analysis showed that early group, nulliparity and pre‐pregnancy body mass index were associated with hypertensive disorders of pregnancy.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>These results suggest that maternal complications, including hypertensive disorders of pregnancy and cesarean delivery, were higher in the early group than in the late group. Earlier intervention for GDM might be associated with a reduction in large‐for‐gestational‐age infants.</jats:p></jats:sec> Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan Journal of Diabetes Investigation
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series Journal of Diabetes Investigation
source_id 49
title Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
title_unstemmed Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
title_full Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
title_fullStr Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
title_full_unstemmed Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
title_short Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
title_sort comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in japan
topic General Medicine
Endocrinology, Diabetes and Metabolism
Internal Medicine
url http://dx.doi.org/10.1111/jdi.13101
publishDate 2020
physical 216-222
description <jats:title>Abstract</jats:title><jats:sec><jats:title>Aims/Introduction</jats:title><jats:p>To compare pregnancy outcomes between women with gestational diabetes mellitus (GDM) diagnosed early and late in pregnancy in Japan.</jats:p></jats:sec><jats:sec><jats:title>Materials and Methods</jats:title><jats:p>We examined women diagnosed with GDM in this multi‐institutional retrospective study. Women were divided into two groups by gestational age at diagnosis: &lt;24 weeks of gestation (early group, 14.4 ± 4.2 weeks) and ≥24 weeks of gestation (late group, 29.6 ± 3.4 weeks). Dietary counseling with self‐monitoring of blood glucose with or without insulin therapy was initiated for both groups. Pregnancy outcomes were compared between the groups.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Data from 600 early and 881 late group participants from 40 institutions were included. Although pre‐pregnancy body mass index was higher in the early group than in the late group, gestational weight gain was lower in the early group. Hypertensive disorders of pregnancy and cesarean section were more prevalent in the early than in the late group (9.3% vs 4.8%, <jats:italic>P</jats:italic> &lt; 0.001; 34.2% vs 32.0%, <jats:italic>P</jats:italic> &lt; 0.001, respectively). The prevalence of large‐for‐gestational‐age infants was higher in the late than in the early group (24.6% vs 19.7%, respectively, <jats:italic>P</jats:italic> = 0.025). There was no significant difference in other neonatal adverse outcomes between the groups. Multiple logistic regression analysis showed that early group, nulliparity and pre‐pregnancy body mass index were associated with hypertensive disorders of pregnancy.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>These results suggest that maternal complications, including hypertensive disorders of pregnancy and cesarean delivery, were higher in the early group than in the late group. Earlier intervention for GDM might be associated with a reduction in large‐for‐gestational‐age infants.</jats:p></jats:sec>
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author Usami, Tomoka, Yokoyama, Maki, Ueno, Megumi, Iwama, Noriyuki, Sagawa, Norimasa, Kawano, Reo, Waguri, Masako, Sameshima, Hiroshi, Hiramatsu, Yuji, Sugiyama, Takashi
author_facet Usami, Tomoka, Yokoyama, Maki, Ueno, Megumi, Iwama, Noriyuki, Sagawa, Norimasa, Kawano, Reo, Waguri, Masako, Sameshima, Hiroshi, Hiramatsu, Yuji, Sugiyama, Takashi, Usami, Tomoka, Yokoyama, Maki, Ueno, Megumi, Iwama, Noriyuki, Sagawa, Norimasa, Kawano, Reo, Waguri, Masako, Sameshima, Hiroshi, Hiramatsu, Yuji, Sugiyama, Takashi
author_sort usami, tomoka
container_issue 1
container_start_page 216
container_title Journal of Diabetes Investigation
container_volume 11
description <jats:title>Abstract</jats:title><jats:sec><jats:title>Aims/Introduction</jats:title><jats:p>To compare pregnancy outcomes between women with gestational diabetes mellitus (GDM) diagnosed early and late in pregnancy in Japan.</jats:p></jats:sec><jats:sec><jats:title>Materials and Methods</jats:title><jats:p>We examined women diagnosed with GDM in this multi‐institutional retrospective study. Women were divided into two groups by gestational age at diagnosis: &lt;24 weeks of gestation (early group, 14.4 ± 4.2 weeks) and ≥24 weeks of gestation (late group, 29.6 ± 3.4 weeks). Dietary counseling with self‐monitoring of blood glucose with or without insulin therapy was initiated for both groups. Pregnancy outcomes were compared between the groups.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Data from 600 early and 881 late group participants from 40 institutions were included. Although pre‐pregnancy body mass index was higher in the early group than in the late group, gestational weight gain was lower in the early group. Hypertensive disorders of pregnancy and cesarean section were more prevalent in the early than in the late group (9.3% vs 4.8%, <jats:italic>P</jats:italic> &lt; 0.001; 34.2% vs 32.0%, <jats:italic>P</jats:italic> &lt; 0.001, respectively). The prevalence of large‐for‐gestational‐age infants was higher in the late than in the early group (24.6% vs 19.7%, respectively, <jats:italic>P</jats:italic> = 0.025). There was no significant difference in other neonatal adverse outcomes between the groups. Multiple logistic regression analysis showed that early group, nulliparity and pre‐pregnancy body mass index were associated with hypertensive disorders of pregnancy.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>These results suggest that maternal complications, including hypertensive disorders of pregnancy and cesarean delivery, were higher in the early group than in the late group. Earlier intervention for GDM might be associated with a reduction in large‐for‐gestational‐age infants.</jats:p></jats:sec>
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imprint Wiley, 2020
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institution DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229
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spelling Usami, Tomoka Yokoyama, Maki Ueno, Megumi Iwama, Noriyuki Sagawa, Norimasa Kawano, Reo Waguri, Masako Sameshima, Hiroshi Hiramatsu, Yuji Sugiyama, Takashi 2040-1116 2040-1124 Wiley General Medicine Endocrinology, Diabetes and Metabolism Internal Medicine http://dx.doi.org/10.1111/jdi.13101 <jats:title>Abstract</jats:title><jats:sec><jats:title>Aims/Introduction</jats:title><jats:p>To compare pregnancy outcomes between women with gestational diabetes mellitus (GDM) diagnosed early and late in pregnancy in Japan.</jats:p></jats:sec><jats:sec><jats:title>Materials and Methods</jats:title><jats:p>We examined women diagnosed with GDM in this multi‐institutional retrospective study. Women were divided into two groups by gestational age at diagnosis: &lt;24 weeks of gestation (early group, 14.4 ± 4.2 weeks) and ≥24 weeks of gestation (late group, 29.6 ± 3.4 weeks). Dietary counseling with self‐monitoring of blood glucose with or without insulin therapy was initiated for both groups. Pregnancy outcomes were compared between the groups.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Data from 600 early and 881 late group participants from 40 institutions were included. Although pre‐pregnancy body mass index was higher in the early group than in the late group, gestational weight gain was lower in the early group. Hypertensive disorders of pregnancy and cesarean section were more prevalent in the early than in the late group (9.3% vs 4.8%, <jats:italic>P</jats:italic> &lt; 0.001; 34.2% vs 32.0%, <jats:italic>P</jats:italic> &lt; 0.001, respectively). The prevalence of large‐for‐gestational‐age infants was higher in the late than in the early group (24.6% vs 19.7%, respectively, <jats:italic>P</jats:italic> = 0.025). There was no significant difference in other neonatal adverse outcomes between the groups. Multiple logistic regression analysis showed that early group, nulliparity and pre‐pregnancy body mass index were associated with hypertensive disorders of pregnancy.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>These results suggest that maternal complications, including hypertensive disorders of pregnancy and cesarean delivery, were higher in the early group than in the late group. Earlier intervention for GDM might be associated with a reduction in large‐for‐gestational‐age infants.</jats:p></jats:sec> Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan Journal of Diabetes Investigation
spellingShingle Usami, Tomoka, Yokoyama, Maki, Ueno, Megumi, Iwama, Noriyuki, Sagawa, Norimasa, Kawano, Reo, Waguri, Masako, Sameshima, Hiroshi, Hiramatsu, Yuji, Sugiyama, Takashi, Journal of Diabetes Investigation, Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan, General Medicine, Endocrinology, Diabetes and Metabolism, Internal Medicine
title Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
title_full Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
title_fullStr Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
title_full_unstemmed Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
title_short Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
title_sort comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in japan
title_unstemmed Comparison of pregnancy outcomes between women with early‐onset and late‐onset gestational diabetes in a retrospective multi‐institutional study in Japan
topic General Medicine, Endocrinology, Diabetes and Metabolism, Internal Medicine
url http://dx.doi.org/10.1111/jdi.13101