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Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture
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| Zeitschriftentitel: | Scandinavian Journal of Immunology |
|---|---|
| Personen und Körperschaften: | , |
| In: | Scandinavian Journal of Immunology, 5, 1976, 6-7, S. 789-794 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
LITWIN, S. D. HARTMAN, N. LITWIN, S. D. HARTMAN, N. |
|---|---|
| author |
LITWIN, S. D. HARTMAN, N. |
| spellingShingle |
LITWIN, S. D. HARTMAN, N. Scandinavian Journal of Immunology Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture Immunology General Medicine |
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litwin, s. d. |
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LITWIN, S. D. HARTMAN, N. 0300-9475 1365-3083 Wiley Immunology General Medicine http://dx.doi.org/10.1111/j.1365-3083.1976.tb03028.x <jats:p>A human lymphoblastoid line, in continuous culture for over 3 years, showed changes in Ig expression with time. The following pattern of events was suggested by studies of Ig synthesis and secretion performed at intervals. In a mass culture containing a heterogeneous cell population, Ig expression may shift because of selection acting on the different phenotypes. In human lymphoblastoid lines there may be a tendency for selection to favor IgMx‐producing cells. In clones, including those that synthesize multiple H chains, substantial determinism for Ig expression is present.</jats:p> Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture Scandinavian Journal of Immunology |
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Wiley, 1976 |
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Scandinavian Journal of Immunology |
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| title |
Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture |
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Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture |
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Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture |
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Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture |
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Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture |
| title_short |
Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture |
| title_sort |
change in ig expression of a human lymphoblastoid line during long‐term culture |
| topic |
Immunology General Medicine |
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http://dx.doi.org/10.1111/j.1365-3083.1976.tb03028.x |
| publishDate |
1976 |
| physical |
789-794 |
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<jats:p>A human lymphoblastoid line, in continuous culture for over 3 years, showed changes in Ig expression with time. The following pattern of events was suggested by studies of Ig synthesis and secretion performed at intervals. In a mass culture containing a heterogeneous cell population, Ig expression may shift because of selection acting on the different phenotypes. In human lymphoblastoid lines there may be a tendency for selection to favor IgMx‐producing cells. In clones, including those that synthesize multiple H chains, substantial determinism for Ig expression is present.</jats:p> |
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| author | LITWIN, S. D., HARTMAN, N. |
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| description | <jats:p>A human lymphoblastoid line, in continuous culture for over 3 years, showed changes in Ig expression with time. The following pattern of events was suggested by studies of Ig synthesis and secretion performed at intervals. In a mass culture containing a heterogeneous cell population, Ig expression may shift because of selection acting on the different phenotypes. In human lymphoblastoid lines there may be a tendency for selection to favor IgMx‐producing cells. In clones, including those that synthesize multiple H chains, substantial determinism for Ig expression is present.</jats:p> |
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| imprint | Wiley, 1976 |
| imprint_str_mv | Wiley, 1976 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Zi4, DE-Gla1, DE-15, DE-Pl11, DE-Rs1, DE-14, DE-105, DE-Ch1, DE-L229 |
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| series | Scandinavian Journal of Immunology |
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| spelling | LITWIN, S. D. HARTMAN, N. 0300-9475 1365-3083 Wiley Immunology General Medicine http://dx.doi.org/10.1111/j.1365-3083.1976.tb03028.x <jats:p>A human lymphoblastoid line, in continuous culture for over 3 years, showed changes in Ig expression with time. The following pattern of events was suggested by studies of Ig synthesis and secretion performed at intervals. In a mass culture containing a heterogeneous cell population, Ig expression may shift because of selection acting on the different phenotypes. In human lymphoblastoid lines there may be a tendency for selection to favor IgMx‐producing cells. In clones, including those that synthesize multiple H chains, substantial determinism for Ig expression is present.</jats:p> Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture Scandinavian Journal of Immunology |
| spellingShingle | LITWIN, S. D., HARTMAN, N., Scandinavian Journal of Immunology, Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture, Immunology, General Medicine |
| title | Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture |
| title_full | Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture |
| title_fullStr | Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture |
| title_full_unstemmed | Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture |
| title_short | Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture |
| title_sort | change in ig expression of a human lymphoblastoid line during long‐term culture |
| title_unstemmed | Change in Ig Expression of a Human Lymphoblastoid Line During Long‐Term Culture |
| topic | Immunology, General Medicine |
| url | http://dx.doi.org/10.1111/j.1365-3083.1976.tb03028.x |