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Adiponectin, an Unlocking Adipocytokine
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| Zeitschriftentitel: | Cardiovascular Therapeutics |
|---|---|
| Personen und Körperschaften: | , , , , , , |
| In: | Cardiovascular Therapeutics, 27, 2009, 1, S. 59-75 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Sun, Yiyi Xun, Keli Wang, Changguang Zhao, Haiyu Bi, Huichang Chen, Xiuping Wang, Yitao Sun, Yiyi Xun, Keli Wang, Changguang Zhao, Haiyu Bi, Huichang Chen, Xiuping Wang, Yitao |
|---|---|
| author |
Sun, Yiyi Xun, Keli Wang, Changguang Zhao, Haiyu Bi, Huichang Chen, Xiuping Wang, Yitao |
| spellingShingle |
Sun, Yiyi Xun, Keli Wang, Changguang Zhao, Haiyu Bi, Huichang Chen, Xiuping Wang, Yitao Cardiovascular Therapeutics Adiponectin, an Unlocking Adipocytokine Pharmacology (medical) Cardiology and Cardiovascular Medicine Pharmacology General Medicine |
| author_sort |
sun, yiyi |
| spelling |
Sun, Yiyi Xun, Keli Wang, Changguang Zhao, Haiyu Bi, Huichang Chen, Xiuping Wang, Yitao 1755-5914 1755-5922 Wiley Pharmacology (medical) Cardiology and Cardiovascular Medicine Pharmacology General Medicine http://dx.doi.org/10.1111/j.1755-5922.2008.00069.x <jats:p>A large number of studies revealed that adiponectin, a protein secreted specifically by adipose tissue, exhibits antiinflammatory, antiatherogenic, and antidiabetic properties. This 247‐amino acid protein contains four differentiable domains and exists in five different configurations, which binds three kinds of receptors. The plasma adiponectin concentration is at amazing microgram level and the gender difference is very clear. Obese subjects showed decreased plasma level of adiponectin while exercise seems to restore it. Many researchers demonstrated that it could be a reliable biomarker for multiple diseases. However, there is controversy about its role in inflammation since its plasma concentration decreases in some inflammatory diseases and increases under some other inflammatory conditions. The signal transduction pathway is still not very clear yet. Could adiponectin be a promising drug target?</jats:p> Adiponectin, an Unlocking Adipocytokine Cardiovascular Therapeutics |
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| title |
Adiponectin, an Unlocking Adipocytokine |
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Adiponectin, an Unlocking Adipocytokine |
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Adiponectin, an Unlocking Adipocytokine |
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Adiponectin, an Unlocking Adipocytokine |
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Adiponectin, an Unlocking Adipocytokine |
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Adiponectin, an Unlocking Adipocytokine |
| title_sort |
adiponectin, an unlocking adipocytokine |
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Pharmacology (medical) Cardiology and Cardiovascular Medicine Pharmacology General Medicine |
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http://dx.doi.org/10.1111/j.1755-5922.2008.00069.x |
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<jats:p>A large number of studies revealed that adiponectin, a protein secreted specifically by adipose tissue, exhibits antiinflammatory, antiatherogenic, and antidiabetic properties. This 247‐amino acid protein contains four differentiable domains and exists in five different configurations, which binds three kinds of receptors. The plasma adiponectin concentration is at amazing microgram level and the gender difference is very clear. Obese subjects showed decreased plasma level of adiponectin while exercise seems to restore it. Many researchers demonstrated that it could be a reliable biomarker for multiple diseases. However, there is controversy about its role in inflammation since its plasma concentration decreases in some inflammatory diseases and increases under some other inflammatory conditions. The signal transduction pathway is still not very clear yet. Could adiponectin be a promising drug target?</jats:p> |
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| author | Sun, Yiyi, Xun, Keli, Wang, Changguang, Zhao, Haiyu, Bi, Huichang, Chen, Xiuping, Wang, Yitao |
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| description | <jats:p>A large number of studies revealed that adiponectin, a protein secreted specifically by adipose tissue, exhibits antiinflammatory, antiatherogenic, and antidiabetic properties. This 247‐amino acid protein contains four differentiable domains and exists in five different configurations, which binds three kinds of receptors. The plasma adiponectin concentration is at amazing microgram level and the gender difference is very clear. Obese subjects showed decreased plasma level of adiponectin while exercise seems to restore it. Many researchers demonstrated that it could be a reliable biomarker for multiple diseases. However, there is controversy about its role in inflammation since its plasma concentration decreases in some inflammatory diseases and increases under some other inflammatory conditions. The signal transduction pathway is still not very clear yet. Could adiponectin be a promising drug target?</jats:p> |
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| series | Cardiovascular Therapeutics |
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| spelling | Sun, Yiyi Xun, Keli Wang, Changguang Zhao, Haiyu Bi, Huichang Chen, Xiuping Wang, Yitao 1755-5914 1755-5922 Wiley Pharmacology (medical) Cardiology and Cardiovascular Medicine Pharmacology General Medicine http://dx.doi.org/10.1111/j.1755-5922.2008.00069.x <jats:p>A large number of studies revealed that adiponectin, a protein secreted specifically by adipose tissue, exhibits antiinflammatory, antiatherogenic, and antidiabetic properties. This 247‐amino acid protein contains four differentiable domains and exists in five different configurations, which binds three kinds of receptors. The plasma adiponectin concentration is at amazing microgram level and the gender difference is very clear. Obese subjects showed decreased plasma level of adiponectin while exercise seems to restore it. Many researchers demonstrated that it could be a reliable biomarker for multiple diseases. However, there is controversy about its role in inflammation since its plasma concentration decreases in some inflammatory diseases and increases under some other inflammatory conditions. The signal transduction pathway is still not very clear yet. Could adiponectin be a promising drug target?</jats:p> Adiponectin, an Unlocking Adipocytokine Cardiovascular Therapeutics |
| spellingShingle | Sun, Yiyi, Xun, Keli, Wang, Changguang, Zhao, Haiyu, Bi, Huichang, Chen, Xiuping, Wang, Yitao, Cardiovascular Therapeutics, Adiponectin, an Unlocking Adipocytokine, Pharmacology (medical), Cardiology and Cardiovascular Medicine, Pharmacology, General Medicine |
| title | Adiponectin, an Unlocking Adipocytokine |
| title_full | Adiponectin, an Unlocking Adipocytokine |
| title_fullStr | Adiponectin, an Unlocking Adipocytokine |
| title_full_unstemmed | Adiponectin, an Unlocking Adipocytokine |
| title_short | Adiponectin, an Unlocking Adipocytokine |
| title_sort | adiponectin, an unlocking adipocytokine |
| title_unstemmed | Adiponectin, an Unlocking Adipocytokine |
| topic | Pharmacology (medical), Cardiology and Cardiovascular Medicine, Pharmacology, General Medicine |
| url | http://dx.doi.org/10.1111/j.1755-5922.2008.00069.x |