author_facet He, Ye
Casaccia‐Bonnefil, Patrizia
He, Ye
Casaccia‐Bonnefil, Patrizia
author He, Ye
Casaccia‐Bonnefil, Patrizia
spellingShingle He, Ye
Casaccia‐Bonnefil, Patrizia
Journal of Neurochemistry
The Yin and Yang of YY1 in the nervous system
Cellular and Molecular Neuroscience
Biochemistry
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spelling He, Ye Casaccia‐Bonnefil, Patrizia 0022-3042 1471-4159 Wiley Cellular and Molecular Neuroscience Biochemistry http://dx.doi.org/10.1111/j.1471-4159.2008.05486.x <jats:title>Abstract</jats:title><jats:p>The transcription factor Yin Yang 1 (YY1) is a multifunctional protein that can activate or repress gene expression depending on the cellular context. YY1 is ubiquitously expressed and highly conserved between species. However, its role varies in diverse cell types and includes proliferation, differentiation, and apoptosis. This review will focus on the function of YY1 in the nervous system including its role in neural development, neuronal function, developmental myelination, and neurological disease. The multiple functions of YY1 in distinct cell types are reviewed and the possible mechanisms underlying the cell specificity for these functions are discussed.</jats:p> The Yin and Yang of YY1 in the nervous system Journal of Neurochemistry
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title The Yin and Yang of YY1 in the nervous system
title_unstemmed The Yin and Yang of YY1 in the nervous system
title_full The Yin and Yang of YY1 in the nervous system
title_fullStr The Yin and Yang of YY1 in the nervous system
title_full_unstemmed The Yin and Yang of YY1 in the nervous system
title_short The Yin and Yang of YY1 in the nervous system
title_sort the yin and yang of yy1 in the nervous system
topic Cellular and Molecular Neuroscience
Biochemistry
url http://dx.doi.org/10.1111/j.1471-4159.2008.05486.x
publishDate 2008
physical 1493-1502
description <jats:title>Abstract</jats:title><jats:p>The transcription factor Yin Yang 1 (YY1) is a multifunctional protein that can activate or repress gene expression depending on the cellular context. YY1 is ubiquitously expressed and highly conserved between species. However, its role varies in diverse cell types and includes proliferation, differentiation, and apoptosis. This review will focus on the function of YY1 in the nervous system including its role in neural development, neuronal function, developmental myelination, and neurological disease. The multiple functions of YY1 in distinct cell types are reviewed and the possible mechanisms underlying the cell specificity for these functions are discussed.</jats:p>
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author He, Ye, Casaccia‐Bonnefil, Patrizia
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description <jats:title>Abstract</jats:title><jats:p>The transcription factor Yin Yang 1 (YY1) is a multifunctional protein that can activate or repress gene expression depending on the cellular context. YY1 is ubiquitously expressed and highly conserved between species. However, its role varies in diverse cell types and includes proliferation, differentiation, and apoptosis. This review will focus on the function of YY1 in the nervous system including its role in neural development, neuronal function, developmental myelination, and neurological disease. The multiple functions of YY1 in distinct cell types are reviewed and the possible mechanisms underlying the cell specificity for these functions are discussed.</jats:p>
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spelling He, Ye Casaccia‐Bonnefil, Patrizia 0022-3042 1471-4159 Wiley Cellular and Molecular Neuroscience Biochemistry http://dx.doi.org/10.1111/j.1471-4159.2008.05486.x <jats:title>Abstract</jats:title><jats:p>The transcription factor Yin Yang 1 (YY1) is a multifunctional protein that can activate or repress gene expression depending on the cellular context. YY1 is ubiquitously expressed and highly conserved between species. However, its role varies in diverse cell types and includes proliferation, differentiation, and apoptosis. This review will focus on the function of YY1 in the nervous system including its role in neural development, neuronal function, developmental myelination, and neurological disease. The multiple functions of YY1 in distinct cell types are reviewed and the possible mechanisms underlying the cell specificity for these functions are discussed.</jats:p> The Yin and Yang of YY1 in the nervous system Journal of Neurochemistry
spellingShingle He, Ye, Casaccia‐Bonnefil, Patrizia, Journal of Neurochemistry, The Yin and Yang of YY1 in the nervous system, Cellular and Molecular Neuroscience, Biochemistry
title The Yin and Yang of YY1 in the nervous system
title_full The Yin and Yang of YY1 in the nervous system
title_fullStr The Yin and Yang of YY1 in the nervous system
title_full_unstemmed The Yin and Yang of YY1 in the nervous system
title_short The Yin and Yang of YY1 in the nervous system
title_sort the yin and yang of yy1 in the nervous system
title_unstemmed The Yin and Yang of YY1 in the nervous system
topic Cellular and Molecular Neuroscience, Biochemistry
url http://dx.doi.org/10.1111/j.1471-4159.2008.05486.x