author_facet Pfitzenmaier, Jesco
Pritsch, Maria
Haferkamp, Axel
Jakobi, Hildegard
Fritsch, Frederik
Gilfrich, Christian
Djakovic, Nenad
Buse, Stephan
Pahernik, Sascha
Hohenfellner, Markus
Pfitzenmaier, Jesco
Pritsch, Maria
Haferkamp, Axel
Jakobi, Hildegard
Fritsch, Frederik
Gilfrich, Christian
Djakovic, Nenad
Buse, Stephan
Pahernik, Sascha
Hohenfellner, Markus
author Pfitzenmaier, Jesco
Pritsch, Maria
Haferkamp, Axel
Jakobi, Hildegard
Fritsch, Frederik
Gilfrich, Christian
Djakovic, Nenad
Buse, Stephan
Pahernik, Sascha
Hohenfellner, Markus
spellingShingle Pfitzenmaier, Jesco
Pritsch, Maria
Haferkamp, Axel
Jakobi, Hildegard
Fritsch, Frederik
Gilfrich, Christian
Djakovic, Nenad
Buse, Stephan
Pahernik, Sascha
Hohenfellner, Markus
BJU International
Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
Urology
author_sort pfitzenmaier, jesco
spelling Pfitzenmaier, Jesco Pritsch, Maria Haferkamp, Axel Jakobi, Hildegard Fritsch, Frederik Gilfrich, Christian Djakovic, Nenad Buse, Stephan Pahernik, Sascha Hohenfellner, Markus 1464-4096 1464-410X Wiley Urology http://dx.doi.org/10.1111/j.1464-410x.2008.08149.x <jats:sec><jats:title>OBJECTIVES</jats:title><jats:p>To evaluate the effect of body mass index (BMI) on the histopathological and clinical outcome in prostate cancer.</jats:p></jats:sec><jats:sec><jats:title>PATIENTS AND METHODS</jats:title><jats:p>In a prospective urological cancer database, 620 patients with prostate cancer had a radical prostatectomy (RP) as a curative treatment. The patients were categorized into three groups of BMI (kg/m<jats:sup>2</jats:sup>); ≤25.0 (190, ‘normal weight’), &gt;25.0–30.0 (343, ‘overweight’) and &gt;30.0 (87, ‘obese’). We evaluated the histopathological features and the clinical follow‐up after RP. The median (range) age of the men was 64.4 (41.1–80.1) years and the median follow‐up 5.5 (0.1–15.1) years. The preoperative median prostate‐specific antigen (PSA) levels for normal, overweight and obese patients were 9.0 (0.3–133.0), 8.9 (0.4–230.0) and 9.2 (0.5–194.0) ng/mL, respectively.</jats:p></jats:sec><jats:sec><jats:title>RESULTS</jats:title><jats:p>Serum PSA levels were no different among the three groups (<jats:italic>P</jats:italic> = 0.92). The normal, overweight and obese patients had organ‐confined prostate cancer in 53.7%, 57.1% and 58.6%, respectively (<jats:italic>P</jats:italic> = 0.34) and had lymph node metastases in 7.9%, 7.6% and 4.6% (<jats:italic>P</jats:italic> = 0.58). Tumour grading was no different for the three groups (<jats:italic>P</jats:italic> = 0.25). The PSA recurrence‐free, prostate cancer‐specific and overall survival for the three BMI groups did not differ significantly (each <jats:italic>P</jats:italic> &gt; 0.05).</jats:p></jats:sec><jats:sec><jats:title>CONCLUSION</jats:title><jats:p>The BMI cannot be shown to be a predictor of adverse prognosis either for histopathological features or for the clinical outcome, e.g. PSA‐free, prostate cancer‐specific and overall survival, in a mid‐European study population after RP.</jats:p></jats:sec> Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population? BJU International
doi_str_mv 10.1111/j.1464-410x.2008.08149.x
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title Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
title_unstemmed Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
title_full Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
title_fullStr Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
title_full_unstemmed Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
title_short Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
title_sort is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐european study population?
topic Urology
url http://dx.doi.org/10.1111/j.1464-410x.2008.08149.x
publishDate 2009
physical 877-882
description <jats:sec><jats:title>OBJECTIVES</jats:title><jats:p>To evaluate the effect of body mass index (BMI) on the histopathological and clinical outcome in prostate cancer.</jats:p></jats:sec><jats:sec><jats:title>PATIENTS AND METHODS</jats:title><jats:p>In a prospective urological cancer database, 620 patients with prostate cancer had a radical prostatectomy (RP) as a curative treatment. The patients were categorized into three groups of BMI (kg/m<jats:sup>2</jats:sup>); ≤25.0 (190, ‘normal weight’), &gt;25.0–30.0 (343, ‘overweight’) and &gt;30.0 (87, ‘obese’). We evaluated the histopathological features and the clinical follow‐up after RP. The median (range) age of the men was 64.4 (41.1–80.1) years and the median follow‐up 5.5 (0.1–15.1) years. The preoperative median prostate‐specific antigen (PSA) levels for normal, overweight and obese patients were 9.0 (0.3–133.0), 8.9 (0.4–230.0) and 9.2 (0.5–194.0) ng/mL, respectively.</jats:p></jats:sec><jats:sec><jats:title>RESULTS</jats:title><jats:p>Serum PSA levels were no different among the three groups (<jats:italic>P</jats:italic> = 0.92). The normal, overweight and obese patients had organ‐confined prostate cancer in 53.7%, 57.1% and 58.6%, respectively (<jats:italic>P</jats:italic> = 0.34) and had lymph node metastases in 7.9%, 7.6% and 4.6% (<jats:italic>P</jats:italic> = 0.58). Tumour grading was no different for the three groups (<jats:italic>P</jats:italic> = 0.25). The PSA recurrence‐free, prostate cancer‐specific and overall survival for the three BMI groups did not differ significantly (each <jats:italic>P</jats:italic> &gt; 0.05).</jats:p></jats:sec><jats:sec><jats:title>CONCLUSION</jats:title><jats:p>The BMI cannot be shown to be a predictor of adverse prognosis either for histopathological features or for the clinical outcome, e.g. PSA‐free, prostate cancer‐specific and overall survival, in a mid‐European study population after RP.</jats:p></jats:sec>
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author Pfitzenmaier, Jesco, Pritsch, Maria, Haferkamp, Axel, Jakobi, Hildegard, Fritsch, Frederik, Gilfrich, Christian, Djakovic, Nenad, Buse, Stephan, Pahernik, Sascha, Hohenfellner, Markus
author_facet Pfitzenmaier, Jesco, Pritsch, Maria, Haferkamp, Axel, Jakobi, Hildegard, Fritsch, Frederik, Gilfrich, Christian, Djakovic, Nenad, Buse, Stephan, Pahernik, Sascha, Hohenfellner, Markus, Pfitzenmaier, Jesco, Pritsch, Maria, Haferkamp, Axel, Jakobi, Hildegard, Fritsch, Frederik, Gilfrich, Christian, Djakovic, Nenad, Buse, Stephan, Pahernik, Sascha, Hohenfellner, Markus
author_sort pfitzenmaier, jesco
container_issue 7
container_start_page 877
container_title BJU International
container_volume 103
description <jats:sec><jats:title>OBJECTIVES</jats:title><jats:p>To evaluate the effect of body mass index (BMI) on the histopathological and clinical outcome in prostate cancer.</jats:p></jats:sec><jats:sec><jats:title>PATIENTS AND METHODS</jats:title><jats:p>In a prospective urological cancer database, 620 patients with prostate cancer had a radical prostatectomy (RP) as a curative treatment. The patients were categorized into three groups of BMI (kg/m<jats:sup>2</jats:sup>); ≤25.0 (190, ‘normal weight’), &gt;25.0–30.0 (343, ‘overweight’) and &gt;30.0 (87, ‘obese’). We evaluated the histopathological features and the clinical follow‐up after RP. The median (range) age of the men was 64.4 (41.1–80.1) years and the median follow‐up 5.5 (0.1–15.1) years. The preoperative median prostate‐specific antigen (PSA) levels for normal, overweight and obese patients were 9.0 (0.3–133.0), 8.9 (0.4–230.0) and 9.2 (0.5–194.0) ng/mL, respectively.</jats:p></jats:sec><jats:sec><jats:title>RESULTS</jats:title><jats:p>Serum PSA levels were no different among the three groups (<jats:italic>P</jats:italic> = 0.92). The normal, overweight and obese patients had organ‐confined prostate cancer in 53.7%, 57.1% and 58.6%, respectively (<jats:italic>P</jats:italic> = 0.34) and had lymph node metastases in 7.9%, 7.6% and 4.6% (<jats:italic>P</jats:italic> = 0.58). Tumour grading was no different for the three groups (<jats:italic>P</jats:italic> = 0.25). The PSA recurrence‐free, prostate cancer‐specific and overall survival for the three BMI groups did not differ significantly (each <jats:italic>P</jats:italic> &gt; 0.05).</jats:p></jats:sec><jats:sec><jats:title>CONCLUSION</jats:title><jats:p>The BMI cannot be shown to be a predictor of adverse prognosis either for histopathological features or for the clinical outcome, e.g. PSA‐free, prostate cancer‐specific and overall survival, in a mid‐European study population after RP.</jats:p></jats:sec>
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spelling Pfitzenmaier, Jesco Pritsch, Maria Haferkamp, Axel Jakobi, Hildegard Fritsch, Frederik Gilfrich, Christian Djakovic, Nenad Buse, Stephan Pahernik, Sascha Hohenfellner, Markus 1464-4096 1464-410X Wiley Urology http://dx.doi.org/10.1111/j.1464-410x.2008.08149.x <jats:sec><jats:title>OBJECTIVES</jats:title><jats:p>To evaluate the effect of body mass index (BMI) on the histopathological and clinical outcome in prostate cancer.</jats:p></jats:sec><jats:sec><jats:title>PATIENTS AND METHODS</jats:title><jats:p>In a prospective urological cancer database, 620 patients with prostate cancer had a radical prostatectomy (RP) as a curative treatment. The patients were categorized into three groups of BMI (kg/m<jats:sup>2</jats:sup>); ≤25.0 (190, ‘normal weight’), &gt;25.0–30.0 (343, ‘overweight’) and &gt;30.0 (87, ‘obese’). We evaluated the histopathological features and the clinical follow‐up after RP. The median (range) age of the men was 64.4 (41.1–80.1) years and the median follow‐up 5.5 (0.1–15.1) years. The preoperative median prostate‐specific antigen (PSA) levels for normal, overweight and obese patients were 9.0 (0.3–133.0), 8.9 (0.4–230.0) and 9.2 (0.5–194.0) ng/mL, respectively.</jats:p></jats:sec><jats:sec><jats:title>RESULTS</jats:title><jats:p>Serum PSA levels were no different among the three groups (<jats:italic>P</jats:italic> = 0.92). The normal, overweight and obese patients had organ‐confined prostate cancer in 53.7%, 57.1% and 58.6%, respectively (<jats:italic>P</jats:italic> = 0.34) and had lymph node metastases in 7.9%, 7.6% and 4.6% (<jats:italic>P</jats:italic> = 0.58). Tumour grading was no different for the three groups (<jats:italic>P</jats:italic> = 0.25). The PSA recurrence‐free, prostate cancer‐specific and overall survival for the three BMI groups did not differ significantly (each <jats:italic>P</jats:italic> &gt; 0.05).</jats:p></jats:sec><jats:sec><jats:title>CONCLUSION</jats:title><jats:p>The BMI cannot be shown to be a predictor of adverse prognosis either for histopathological features or for the clinical outcome, e.g. PSA‐free, prostate cancer‐specific and overall survival, in a mid‐European study population after RP.</jats:p></jats:sec> Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population? BJU International
spellingShingle Pfitzenmaier, Jesco, Pritsch, Maria, Haferkamp, Axel, Jakobi, Hildegard, Fritsch, Frederik, Gilfrich, Christian, Djakovic, Nenad, Buse, Stephan, Pahernik, Sascha, Hohenfellner, Markus, BJU International, Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?, Urology
title Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
title_full Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
title_fullStr Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
title_full_unstemmed Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
title_short Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
title_sort is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐european study population?
title_unstemmed Is the body mass index a predictor of adverse outcome in prostate cancer after radical prostatectomy in a mid‐European study population?
topic Urology
url http://dx.doi.org/10.1111/j.1464-410x.2008.08149.x