author_facet Piccini, Juan
Robledo, Franco
Romero, Pablo
Piccini, Juan
Robledo, Franco
Romero, Pablo
author Piccini, Juan
Robledo, Franco
Romero, Pablo
spellingShingle Piccini, Juan
Robledo, Franco
Romero, Pablo
International Transactions in Operational Research
Complexity among combinatorial problems from epidemics
Management of Technology and Innovation
Management Science and Operations Research
Strategy and Management
Computer Science Applications
Business and International Management
author_sort piccini, juan
spelling Piccini, Juan Robledo, Franco Romero, Pablo 0969-6016 1475-3995 Wiley Management of Technology and Innovation Management Science and Operations Research Strategy and Management Computer Science Applications Business and International Management http://dx.doi.org/10.1111/itor.12444 <jats:title>Abstract</jats:title><jats:p>A cornerstone in epidemic modeling is the classical susceptible–infected–removed model, or SIR. In this model, individuals are divided into three classes: susceptible (those who can be infected), infected, and removed (those who suffered the infection and recovered, gaining immunity from further contact with infected individuals). Transitions <jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/itor12444-math-0001.png" xlink:title="urn:x-wiley:09696016:media:itor12444:itor12444-math-0001" /> occur at constant rates <jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/itor12444-math-0002.png" xlink:title="urn:x-wiley:09696016:media:itor12444:itor12444-math-0002" />. The SIR model is both simple and useful to understand cascading failures in a network. Nevertheless, a shortcoming is the unrealistic assumption of random contacts in a fully mixed large population. More realistic models are available from authoritative literature in the field. They consider a graph and an epidemic spread governed by probabilistic rules. In this paper, a combinatorial optimization problem is introduced using graph‐theoretic terminology, inspired by an extremal analysis of epidemic modeling. The contributions are threefold. First, a general node immunization problem is defined for node immunization under budget requirements, using probabilistic networks. The goal is to minimize the expected number of deaths under a particular choice of nodes in the system to be immunized. In the second stage, a highly virulent environment leads to a purely combinatorial problem without probabilistic law, called the graph fragmentation problem (GFP). We prove the corresponding decision version for the GFP belongs to the class of <jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/itor12444-math-0003.png" xlink:title="urn:x-wiley:09696016:media:itor12444:itor12444-math-0003" />‐complete problems. As a corollary, SIR‐based models also belong to this set. Third, a GRASP (greedy randomized adaptive search procedure) heuristic enriched with a path‐relinking post‐optimization phase is developed for the GFP. Finally, an experimental analysis is carried out under graphs taken from real‐life applications.</jats:p> Complexity among combinatorial problems from epidemics International Transactions in Operational Research
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series International Transactions in Operational Research
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title Complexity among combinatorial problems from epidemics
title_unstemmed Complexity among combinatorial problems from epidemics
title_full Complexity among combinatorial problems from epidemics
title_fullStr Complexity among combinatorial problems from epidemics
title_full_unstemmed Complexity among combinatorial problems from epidemics
title_short Complexity among combinatorial problems from epidemics
title_sort complexity among combinatorial problems from epidemics
topic Management of Technology and Innovation
Management Science and Operations Research
Strategy and Management
Computer Science Applications
Business and International Management
url http://dx.doi.org/10.1111/itor.12444
publishDate 2018
physical 295-318
description <jats:title>Abstract</jats:title><jats:p>A cornerstone in epidemic modeling is the classical susceptible–infected–removed model, or SIR. In this model, individuals are divided into three classes: susceptible (those who can be infected), infected, and removed (those who suffered the infection and recovered, gaining immunity from further contact with infected individuals). Transitions <jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/itor12444-math-0001.png" xlink:title="urn:x-wiley:09696016:media:itor12444:itor12444-math-0001" /> occur at constant rates <jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/itor12444-math-0002.png" xlink:title="urn:x-wiley:09696016:media:itor12444:itor12444-math-0002" />. The SIR model is both simple and useful to understand cascading failures in a network. Nevertheless, a shortcoming is the unrealistic assumption of random contacts in a fully mixed large population. More realistic models are available from authoritative literature in the field. They consider a graph and an epidemic spread governed by probabilistic rules. In this paper, a combinatorial optimization problem is introduced using graph‐theoretic terminology, inspired by an extremal analysis of epidemic modeling. The contributions are threefold. First, a general node immunization problem is defined for node immunization under budget requirements, using probabilistic networks. The goal is to minimize the expected number of deaths under a particular choice of nodes in the system to be immunized. In the second stage, a highly virulent environment leads to a purely combinatorial problem without probabilistic law, called the graph fragmentation problem (GFP). We prove the corresponding decision version for the GFP belongs to the class of <jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/itor12444-math-0003.png" xlink:title="urn:x-wiley:09696016:media:itor12444:itor12444-math-0003" />‐complete problems. As a corollary, SIR‐based models also belong to this set. Third, a GRASP (greedy randomized adaptive search procedure) heuristic enriched with a path‐relinking post‐optimization phase is developed for the GFP. Finally, an experimental analysis is carried out under graphs taken from real‐life applications.</jats:p>
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author Piccini, Juan, Robledo, Franco, Romero, Pablo
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author_sort piccini, juan
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description <jats:title>Abstract</jats:title><jats:p>A cornerstone in epidemic modeling is the classical susceptible–infected–removed model, or SIR. In this model, individuals are divided into three classes: susceptible (those who can be infected), infected, and removed (those who suffered the infection and recovered, gaining immunity from further contact with infected individuals). Transitions <jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/itor12444-math-0001.png" xlink:title="urn:x-wiley:09696016:media:itor12444:itor12444-math-0001" /> occur at constant rates <jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/itor12444-math-0002.png" xlink:title="urn:x-wiley:09696016:media:itor12444:itor12444-math-0002" />. The SIR model is both simple and useful to understand cascading failures in a network. Nevertheless, a shortcoming is the unrealistic assumption of random contacts in a fully mixed large population. More realistic models are available from authoritative literature in the field. They consider a graph and an epidemic spread governed by probabilistic rules. In this paper, a combinatorial optimization problem is introduced using graph‐theoretic terminology, inspired by an extremal analysis of epidemic modeling. The contributions are threefold. First, a general node immunization problem is defined for node immunization under budget requirements, using probabilistic networks. The goal is to minimize the expected number of deaths under a particular choice of nodes in the system to be immunized. In the second stage, a highly virulent environment leads to a purely combinatorial problem without probabilistic law, called the graph fragmentation problem (GFP). We prove the corresponding decision version for the GFP belongs to the class of <jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/itor12444-math-0003.png" xlink:title="urn:x-wiley:09696016:media:itor12444:itor12444-math-0003" />‐complete problems. As a corollary, SIR‐based models also belong to this set. Third, a GRASP (greedy randomized adaptive search procedure) heuristic enriched with a path‐relinking post‐optimization phase is developed for the GFP. Finally, an experimental analysis is carried out under graphs taken from real‐life applications.</jats:p>
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spelling Piccini, Juan Robledo, Franco Romero, Pablo 0969-6016 1475-3995 Wiley Management of Technology and Innovation Management Science and Operations Research Strategy and Management Computer Science Applications Business and International Management http://dx.doi.org/10.1111/itor.12444 <jats:title>Abstract</jats:title><jats:p>A cornerstone in epidemic modeling is the classical susceptible–infected–removed model, or SIR. In this model, individuals are divided into three classes: susceptible (those who can be infected), infected, and removed (those who suffered the infection and recovered, gaining immunity from further contact with infected individuals). Transitions <jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/itor12444-math-0001.png" xlink:title="urn:x-wiley:09696016:media:itor12444:itor12444-math-0001" /> occur at constant rates <jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/itor12444-math-0002.png" xlink:title="urn:x-wiley:09696016:media:itor12444:itor12444-math-0002" />. The SIR model is both simple and useful to understand cascading failures in a network. Nevertheless, a shortcoming is the unrealistic assumption of random contacts in a fully mixed large population. More realistic models are available from authoritative literature in the field. They consider a graph and an epidemic spread governed by probabilistic rules. In this paper, a combinatorial optimization problem is introduced using graph‐theoretic terminology, inspired by an extremal analysis of epidemic modeling. The contributions are threefold. First, a general node immunization problem is defined for node immunization under budget requirements, using probabilistic networks. The goal is to minimize the expected number of deaths under a particular choice of nodes in the system to be immunized. In the second stage, a highly virulent environment leads to a purely combinatorial problem without probabilistic law, called the graph fragmentation problem (GFP). We prove the corresponding decision version for the GFP belongs to the class of <jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/itor12444-math-0003.png" xlink:title="urn:x-wiley:09696016:media:itor12444:itor12444-math-0003" />‐complete problems. As a corollary, SIR‐based models also belong to this set. Third, a GRASP (greedy randomized adaptive search procedure) heuristic enriched with a path‐relinking post‐optimization phase is developed for the GFP. Finally, an experimental analysis is carried out under graphs taken from real‐life applications.</jats:p> Complexity among combinatorial problems from epidemics International Transactions in Operational Research
spellingShingle Piccini, Juan, Robledo, Franco, Romero, Pablo, International Transactions in Operational Research, Complexity among combinatorial problems from epidemics, Management of Technology and Innovation, Management Science and Operations Research, Strategy and Management, Computer Science Applications, Business and International Management
title Complexity among combinatorial problems from epidemics
title_full Complexity among combinatorial problems from epidemics
title_fullStr Complexity among combinatorial problems from epidemics
title_full_unstemmed Complexity among combinatorial problems from epidemics
title_short Complexity among combinatorial problems from epidemics
title_sort complexity among combinatorial problems from epidemics
title_unstemmed Complexity among combinatorial problems from epidemics
topic Management of Technology and Innovation, Management Science and Operations Research, Strategy and Management, Computer Science Applications, Business and International Management
url http://dx.doi.org/10.1111/itor.12444