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Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China
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| Zeitschriftentitel: | Haemophilia |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , , , , , , , , , |
| In: | Haemophilia, 24, 2018, 1, S. 126-133 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Li, Z. Wu, J. Zhao, Y. Liu, R. Li, K. Zhou, Y. Wu, R. Yang, R. Zhang, X. Lian, S. Hu, Q. Li, X. Gu, J. Zhou, R. Sun, J. Li, C. Xu, W. Poon, M.‐C. Xiao, J. Li, Z. Wu, J. Zhao, Y. Liu, R. Li, K. Zhou, Y. Wu, R. Yang, R. Zhang, X. Lian, S. Hu, Q. Li, X. Gu, J. Zhou, R. Sun, J. Li, C. Xu, W. Poon, M.‐C. Xiao, J. |
|---|---|
| author |
Li, Z. Wu, J. Zhao, Y. Liu, R. Li, K. Zhou, Y. Wu, R. Yang, R. Zhang, X. Lian, S. Hu, Q. Li, X. Gu, J. Zhou, R. Sun, J. Li, C. Xu, W. Poon, M.‐C. Xiao, J. |
| spellingShingle |
Li, Z. Wu, J. Zhao, Y. Liu, R. Li, K. Zhou, Y. Wu, R. Yang, R. Zhang, X. Lian, S. Hu, Q. Li, X. Gu, J. Zhou, R. Sun, J. Li, C. Xu, W. Poon, M.‐C. Xiao, J. Haemophilia Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China Genetics (clinical) Hematology General Medicine |
| author_sort |
li, z. |
| spelling |
Li, Z. Wu, J. Zhao, Y. Liu, R. Li, K. Zhou, Y. Wu, R. Yang, R. Zhang, X. Lian, S. Hu, Q. Li, X. Gu, J. Zhou, R. Sun, J. Li, C. Xu, W. Poon, M.‐C. Xiao, J. 1351-8216 1365-2516 Wiley Genetics (clinical) Hematology General Medicine http://dx.doi.org/10.1111/hae.13372 <jats:sec><jats:title>Objective</jats:title><jats:p>To explore the influence of medical insurance policy and charity assistance projects on the uptake and discontinuation of regular prophylaxis treatment in Chinese severe haemophilia A children.</jats:p></jats:sec><jats:sec><jats:title>Methodology</jats:title><jats:p>This retrospective study was conducted on children with severe haemophilia A, who received <jats:styled-content style="fixed-case">FVIII</jats:styled-content> prophylaxis treatment at 12 haemophilia centres in China from 1 November 2007 to 31 May 2013.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The average duration of prophylaxis treatment received by haemophilia children significantly increased from 16.7 weeks in 2008 to 32.8 weeks in 2012 (<jats:italic>P </jats:italic><<jats:italic> </jats:italic>.001). The main reason for prophylaxis acceptance included dissatisfaction with previous “on‐demand” regimens, availability of improved local medical insurance policies and patient/family awareness of haemophilia. The main reason for subsequent discontinuation of prophylaxis was economic instability. The upper limit of insurance was up to <jats:styled-content style="fixed-case">RMB</jats:styled-content> 150 000/y (~<jats:styled-content style="fixed-case">USD</jats:styled-content>: 22 000/y) for 80.1% of the insured patients and would be sufficient to cover the continuous low‐dose prophylaxis regimen. However, for many patients the burden of out‐of‐pocket copayment cost represented a risk for poor adherence to regular prophylaxis. In about two third of the patients, the annual out‐of‐pocket copayment cost amounted to >50% of their average annual disposable income. Many patients therefore required assistance from the charity assistance projects, but nonadherence remained prevalent.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Medical insurance policy and charity assistance projects helped haemophilia children to accept and continue prophylaxis regimens. It was the proportion of the out‐of‐pocket copayment cost rather than the upper limit of insurance reimbursement that restricted long‐term regular low‐dose prophylaxis in China.</jats:p></jats:sec> Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China Haemophilia |
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| title |
Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China |
| title_unstemmed |
Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China |
| title_full |
Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China |
| title_fullStr |
Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China |
| title_full_unstemmed |
Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China |
| title_short |
Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China |
| title_sort |
influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia a in china |
| topic |
Genetics (clinical) Hematology General Medicine |
| url |
http://dx.doi.org/10.1111/hae.13372 |
| publishDate |
2018 |
| physical |
126-133 |
| description |
<jats:sec><jats:title>Objective</jats:title><jats:p>To explore the influence of medical insurance policy and charity assistance projects on the uptake and discontinuation of regular prophylaxis treatment in Chinese severe haemophilia A children.</jats:p></jats:sec><jats:sec><jats:title>Methodology</jats:title><jats:p>This retrospective study was conducted on children with severe haemophilia A, who received <jats:styled-content style="fixed-case">FVIII</jats:styled-content> prophylaxis treatment at 12 haemophilia centres in China from 1 November 2007 to 31 May 2013.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The average duration of prophylaxis treatment received by haemophilia children significantly increased from 16.7 weeks in 2008 to 32.8 weeks in 2012 (<jats:italic>P </jats:italic><<jats:italic> </jats:italic>.001). The main reason for prophylaxis acceptance included dissatisfaction with previous “on‐demand” regimens, availability of improved local medical insurance policies and patient/family awareness of haemophilia. The main reason for subsequent discontinuation of prophylaxis was economic instability. The upper limit of insurance was up to <jats:styled-content style="fixed-case">RMB</jats:styled-content> 150 000/y (~<jats:styled-content style="fixed-case">USD</jats:styled-content>: 22 000/y) for 80.1% of the insured patients and would be sufficient to cover the continuous low‐dose prophylaxis regimen. However, for many patients the burden of out‐of‐pocket copayment cost represented a risk for poor adherence to regular prophylaxis. In about two third of the patients, the annual out‐of‐pocket copayment cost amounted to >50% of their average annual disposable income. Many patients therefore required assistance from the charity assistance projects, but nonadherence remained prevalent.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Medical insurance policy and charity assistance projects helped haemophilia children to accept and continue prophylaxis regimens. It was the proportion of the out‐of‐pocket copayment cost rather than the upper limit of insurance reimbursement that restricted long‐term regular low‐dose prophylaxis in China.</jats:p></jats:sec> |
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| author | Li, Z., Wu, J., Zhao, Y., Liu, R., Li, K., Zhou, Y., Wu, R., Yang, R., Zhang, X., Lian, S., Hu, Q., Li, X., Gu, J., Zhou, R., Sun, J., Li, C., Xu, W., Poon, M.‐C., Xiao, J. |
| author_facet | Li, Z., Wu, J., Zhao, Y., Liu, R., Li, K., Zhou, Y., Wu, R., Yang, R., Zhang, X., Lian, S., Hu, Q., Li, X., Gu, J., Zhou, R., Sun, J., Li, C., Xu, W., Poon, M.‐C., Xiao, J., Li, Z., Wu, J., Zhao, Y., Liu, R., Li, K., Zhou, Y., Wu, R., Yang, R., Zhang, X., Lian, S., Hu, Q., Li, X., Gu, J., Zhou, R., Sun, J., Li, C., Xu, W., Poon, M.‐C., Xiao, J. |
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| description | <jats:sec><jats:title>Objective</jats:title><jats:p>To explore the influence of medical insurance policy and charity assistance projects on the uptake and discontinuation of regular prophylaxis treatment in Chinese severe haemophilia A children.</jats:p></jats:sec><jats:sec><jats:title>Methodology</jats:title><jats:p>This retrospective study was conducted on children with severe haemophilia A, who received <jats:styled-content style="fixed-case">FVIII</jats:styled-content> prophylaxis treatment at 12 haemophilia centres in China from 1 November 2007 to 31 May 2013.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The average duration of prophylaxis treatment received by haemophilia children significantly increased from 16.7 weeks in 2008 to 32.8 weeks in 2012 (<jats:italic>P </jats:italic><<jats:italic> </jats:italic>.001). The main reason for prophylaxis acceptance included dissatisfaction with previous “on‐demand” regimens, availability of improved local medical insurance policies and patient/family awareness of haemophilia. The main reason for subsequent discontinuation of prophylaxis was economic instability. The upper limit of insurance was up to <jats:styled-content style="fixed-case">RMB</jats:styled-content> 150 000/y (~<jats:styled-content style="fixed-case">USD</jats:styled-content>: 22 000/y) for 80.1% of the insured patients and would be sufficient to cover the continuous low‐dose prophylaxis regimen. However, for many patients the burden of out‐of‐pocket copayment cost represented a risk for poor adherence to regular prophylaxis. In about two third of the patients, the annual out‐of‐pocket copayment cost amounted to >50% of their average annual disposable income. Many patients therefore required assistance from the charity assistance projects, but nonadherence remained prevalent.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Medical insurance policy and charity assistance projects helped haemophilia children to accept and continue prophylaxis regimens. It was the proportion of the out‐of‐pocket copayment cost rather than the upper limit of insurance reimbursement that restricted long‐term regular low‐dose prophylaxis in China.</jats:p></jats:sec> |
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| institution | DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1 |
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| spelling | Li, Z. Wu, J. Zhao, Y. Liu, R. Li, K. Zhou, Y. Wu, R. Yang, R. Zhang, X. Lian, S. Hu, Q. Li, X. Gu, J. Zhou, R. Sun, J. Li, C. Xu, W. Poon, M.‐C. Xiao, J. 1351-8216 1365-2516 Wiley Genetics (clinical) Hematology General Medicine http://dx.doi.org/10.1111/hae.13372 <jats:sec><jats:title>Objective</jats:title><jats:p>To explore the influence of medical insurance policy and charity assistance projects on the uptake and discontinuation of regular prophylaxis treatment in Chinese severe haemophilia A children.</jats:p></jats:sec><jats:sec><jats:title>Methodology</jats:title><jats:p>This retrospective study was conducted on children with severe haemophilia A, who received <jats:styled-content style="fixed-case">FVIII</jats:styled-content> prophylaxis treatment at 12 haemophilia centres in China from 1 November 2007 to 31 May 2013.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The average duration of prophylaxis treatment received by haemophilia children significantly increased from 16.7 weeks in 2008 to 32.8 weeks in 2012 (<jats:italic>P </jats:italic><<jats:italic> </jats:italic>.001). The main reason for prophylaxis acceptance included dissatisfaction with previous “on‐demand” regimens, availability of improved local medical insurance policies and patient/family awareness of haemophilia. The main reason for subsequent discontinuation of prophylaxis was economic instability. The upper limit of insurance was up to <jats:styled-content style="fixed-case">RMB</jats:styled-content> 150 000/y (~<jats:styled-content style="fixed-case">USD</jats:styled-content>: 22 000/y) for 80.1% of the insured patients and would be sufficient to cover the continuous low‐dose prophylaxis regimen. However, for many patients the burden of out‐of‐pocket copayment cost represented a risk for poor adherence to regular prophylaxis. In about two third of the patients, the annual out‐of‐pocket copayment cost amounted to >50% of their average annual disposable income. Many patients therefore required assistance from the charity assistance projects, but nonadherence remained prevalent.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Medical insurance policy and charity assistance projects helped haemophilia children to accept and continue prophylaxis regimens. It was the proportion of the out‐of‐pocket copayment cost rather than the upper limit of insurance reimbursement that restricted long‐term regular low‐dose prophylaxis in China.</jats:p></jats:sec> Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China Haemophilia |
| spellingShingle | Li, Z., Wu, J., Zhao, Y., Liu, R., Li, K., Zhou, Y., Wu, R., Yang, R., Zhang, X., Lian, S., Hu, Q., Li, X., Gu, J., Zhou, R., Sun, J., Li, C., Xu, W., Poon, M.‐C., Xiao, J., Haemophilia, Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China, Genetics (clinical), Hematology, General Medicine |
| title | Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China |
| title_full | Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China |
| title_fullStr | Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China |
| title_full_unstemmed | Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China |
| title_short | Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China |
| title_sort | influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia a in china |
| title_unstemmed | Influence of medical insurance schemes and charity assistance projects on regular prophylaxis treatment of the boys with severe haemophilia A in China |
| topic | Genetics (clinical), Hematology, General Medicine |
| url | http://dx.doi.org/10.1111/hae.13372 |