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Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease
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| Zeitschriftentitel: | CNS Neuroscience & Therapeutics |
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| Personen und Körperschaften: | , , , , , , , , |
| In: | CNS Neuroscience & Therapeutics, 19, 2013, 9, S. 643-648 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
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| Schlagwörter: |
| author_facet |
Tarragon, Ernesto Lopez, Dolores Estrada, Cristina Ana, Gonzalez‐Cuello Schenker, Esther Pifferi, Fabien Bordet, Regis Richardson, Jill C. Herrero, Maria Trinidad Tarragon, Ernesto Lopez, Dolores Estrada, Cristina Ana, Gonzalez‐Cuello Schenker, Esther Pifferi, Fabien Bordet, Regis Richardson, Jill C. Herrero, Maria Trinidad |
|---|---|
| author |
Tarragon, Ernesto Lopez, Dolores Estrada, Cristina Ana, Gonzalez‐Cuello Schenker, Esther Pifferi, Fabien Bordet, Regis Richardson, Jill C. Herrero, Maria Trinidad |
| spellingShingle |
Tarragon, Ernesto Lopez, Dolores Estrada, Cristina Ana, Gonzalez‐Cuello Schenker, Esther Pifferi, Fabien Bordet, Regis Richardson, Jill C. Herrero, Maria Trinidad CNS Neuroscience & Therapeutics Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease Pharmacology (medical) Physiology (medical) Psychiatry and Mental health Pharmacology |
| author_sort |
tarragon, ernesto |
| spelling |
Tarragon, Ernesto Lopez, Dolores Estrada, Cristina Ana, Gonzalez‐Cuello Schenker, Esther Pifferi, Fabien Bordet, Regis Richardson, Jill C. Herrero, Maria Trinidad 1755-5930 1755-5949 Wiley Pharmacology (medical) Physiology (medical) Psychiatry and Mental health Pharmacology http://dx.doi.org/10.1111/cns.12125 <jats:title>Summary</jats:title><jats:p><jats:italic>Octodon degus</jats:italic> (<jats:italic><jats:styled-content style="fixed-case">O</jats:styled-content>. degus</jats:italic>) is a diurnal rodent that spontaneously develops several physiopathological conditions, analogous in many cases to those experienced by humans. In light of this, <jats:italic><jats:styled-content style="fixed-case">O</jats:styled-content>. degus</jats:italic> has recently been identified as a very valuable animal model for research in several medical fields, especially those concerned with neurodegenerative diseases in which risk is associated with aging. <jats:italic>Octodon degus</jats:italic> spontaneously develops β‐amyloid deposits analogous to those observed in some cases of <jats:styled-content style="fixed-case">A</jats:styled-content>lzheimer's disease (<jats:styled-content style="fixed-case">AD</jats:styled-content>). Moreover, these deposits are thought to be the key feature for <jats:styled-content style="fixed-case">AD</jats:styled-content> diagnosis, and one of the suggested causes of cell loss and cognitive deficit. This review aims to bring together information to support <jats:italic><jats:styled-content style="fixed-case">O</jats:styled-content>. degus</jats:italic> as a valuable model for the study of <jats:styled-content style="fixed-case">AD</jats:styled-content>.</jats:p> <i>Octodon degus</i>: A Model for the Cognitive Impairment Associated with <scp>A</scp>lzheimer's Disease CNS Neuroscience & Therapeutics |
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10.1111/cns.12125 |
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| title |
Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease |
| title_unstemmed |
Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease |
| title_full |
Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease |
| title_fullStr |
Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease |
| title_full_unstemmed |
Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease |
| title_short |
Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease |
| title_sort |
<i>octodon degus</i>: a model for the cognitive impairment associated with <scp>a</scp>lzheimer's disease |
| topic |
Pharmacology (medical) Physiology (medical) Psychiatry and Mental health Pharmacology |
| url |
http://dx.doi.org/10.1111/cns.12125 |
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2013 |
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643-648 |
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<jats:title>Summary</jats:title><jats:p><jats:italic>Octodon degus</jats:italic> (<jats:italic><jats:styled-content style="fixed-case">O</jats:styled-content>. degus</jats:italic>) is a diurnal rodent that spontaneously develops several physiopathological conditions, analogous in many cases to those experienced by humans. In light of this, <jats:italic><jats:styled-content style="fixed-case">O</jats:styled-content>. degus</jats:italic> has recently been identified as a very valuable animal model for research in several medical fields, especially those concerned with neurodegenerative diseases in which risk is associated with aging. <jats:italic>Octodon degus</jats:italic> spontaneously develops β‐amyloid deposits analogous to those observed in some cases of <jats:styled-content style="fixed-case">A</jats:styled-content>lzheimer's disease (<jats:styled-content style="fixed-case">AD</jats:styled-content>). Moreover, these deposits are thought to be the key feature for <jats:styled-content style="fixed-case">AD</jats:styled-content> diagnosis, and one of the suggested causes of cell loss and cognitive deficit. This review aims to bring together information to support <jats:italic><jats:styled-content style="fixed-case">O</jats:styled-content>. degus</jats:italic> as a valuable model for the study of <jats:styled-content style="fixed-case">AD</jats:styled-content>.</jats:p> |
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| author | Tarragon, Ernesto, Lopez, Dolores, Estrada, Cristina, Ana, Gonzalez‐Cuello, Schenker, Esther, Pifferi, Fabien, Bordet, Regis, Richardson, Jill C., Herrero, Maria Trinidad |
| author_facet | Tarragon, Ernesto, Lopez, Dolores, Estrada, Cristina, Ana, Gonzalez‐Cuello, Schenker, Esther, Pifferi, Fabien, Bordet, Regis, Richardson, Jill C., Herrero, Maria Trinidad, Tarragon, Ernesto, Lopez, Dolores, Estrada, Cristina, Ana, Gonzalez‐Cuello, Schenker, Esther, Pifferi, Fabien, Bordet, Regis, Richardson, Jill C., Herrero, Maria Trinidad |
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| description | <jats:title>Summary</jats:title><jats:p><jats:italic>Octodon degus</jats:italic> (<jats:italic><jats:styled-content style="fixed-case">O</jats:styled-content>. degus</jats:italic>) is a diurnal rodent that spontaneously develops several physiopathological conditions, analogous in many cases to those experienced by humans. In light of this, <jats:italic><jats:styled-content style="fixed-case">O</jats:styled-content>. degus</jats:italic> has recently been identified as a very valuable animal model for research in several medical fields, especially those concerned with neurodegenerative diseases in which risk is associated with aging. <jats:italic>Octodon degus</jats:italic> spontaneously develops β‐amyloid deposits analogous to those observed in some cases of <jats:styled-content style="fixed-case">A</jats:styled-content>lzheimer's disease (<jats:styled-content style="fixed-case">AD</jats:styled-content>). Moreover, these deposits are thought to be the key feature for <jats:styled-content style="fixed-case">AD</jats:styled-content> diagnosis, and one of the suggested causes of cell loss and cognitive deficit. This review aims to bring together information to support <jats:italic><jats:styled-content style="fixed-case">O</jats:styled-content>. degus</jats:italic> as a valuable model for the study of <jats:styled-content style="fixed-case">AD</jats:styled-content>.</jats:p> |
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| institution | DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4 |
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| spelling | Tarragon, Ernesto Lopez, Dolores Estrada, Cristina Ana, Gonzalez‐Cuello Schenker, Esther Pifferi, Fabien Bordet, Regis Richardson, Jill C. Herrero, Maria Trinidad 1755-5930 1755-5949 Wiley Pharmacology (medical) Physiology (medical) Psychiatry and Mental health Pharmacology http://dx.doi.org/10.1111/cns.12125 <jats:title>Summary</jats:title><jats:p><jats:italic>Octodon degus</jats:italic> (<jats:italic><jats:styled-content style="fixed-case">O</jats:styled-content>. degus</jats:italic>) is a diurnal rodent that spontaneously develops several physiopathological conditions, analogous in many cases to those experienced by humans. In light of this, <jats:italic><jats:styled-content style="fixed-case">O</jats:styled-content>. degus</jats:italic> has recently been identified as a very valuable animal model for research in several medical fields, especially those concerned with neurodegenerative diseases in which risk is associated with aging. <jats:italic>Octodon degus</jats:italic> spontaneously develops β‐amyloid deposits analogous to those observed in some cases of <jats:styled-content style="fixed-case">A</jats:styled-content>lzheimer's disease (<jats:styled-content style="fixed-case">AD</jats:styled-content>). Moreover, these deposits are thought to be the key feature for <jats:styled-content style="fixed-case">AD</jats:styled-content> diagnosis, and one of the suggested causes of cell loss and cognitive deficit. This review aims to bring together information to support <jats:italic><jats:styled-content style="fixed-case">O</jats:styled-content>. degus</jats:italic> as a valuable model for the study of <jats:styled-content style="fixed-case">AD</jats:styled-content>.</jats:p> <i>Octodon degus</i>: A Model for the Cognitive Impairment Associated with <scp>A</scp>lzheimer's Disease CNS Neuroscience & Therapeutics |
| spellingShingle | Tarragon, Ernesto, Lopez, Dolores, Estrada, Cristina, Ana, Gonzalez‐Cuello, Schenker, Esther, Pifferi, Fabien, Bordet, Regis, Richardson, Jill C., Herrero, Maria Trinidad, CNS Neuroscience & Therapeutics, Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease, Pharmacology (medical), Physiology (medical), Psychiatry and Mental health, Pharmacology |
| title | Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease |
| title_full | Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease |
| title_fullStr | Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease |
| title_full_unstemmed | Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease |
| title_short | Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease |
| title_sort | <i>octodon degus</i>: a model for the cognitive impairment associated with <scp>a</scp>lzheimer's disease |
| title_unstemmed | Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease |
| topic | Pharmacology (medical), Physiology (medical), Psychiatry and Mental health, Pharmacology |
| url | http://dx.doi.org/10.1111/cns.12125 |