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What's Next for Acute Heart Failure Research?
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| Zeitschriftentitel: | Academic Emergency Medicine |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , , , , , , , |
| In: | Academic Emergency Medicine, 25, 2018, 1, S. 85-93 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Collins, Sean P. Levy, Phillip D. Fermann, Gregory J. Givertz, Michael M. Martindale, Jennifer M. Pang, Peter S. Storrow, Alan B. Diercks, Deborah D. Michael Felker, G. Fonarow, Gregg C. Lanfear, David J. Lenihan, Daniel J. Lindenfeld, JoAnn M. Frank Peacock, W. Sawyer, Douglas M. Teerlink, John R. Butler, Javed Collins, Sean P. Levy, Phillip D. Fermann, Gregory J. Givertz, Michael M. Martindale, Jennifer M. Pang, Peter S. Storrow, Alan B. Diercks, Deborah D. Michael Felker, G. Fonarow, Gregg C. Lanfear, David J. Lenihan, Daniel J. Lindenfeld, JoAnn M. Frank Peacock, W. Sawyer, Douglas M. Teerlink, John R. Butler, Javed |
|---|---|
| author |
Collins, Sean P. Levy, Phillip D. Fermann, Gregory J. Givertz, Michael M. Martindale, Jennifer M. Pang, Peter S. Storrow, Alan B. Diercks, Deborah D. Michael Felker, G. Fonarow, Gregg C. Lanfear, David J. Lenihan, Daniel J. Lindenfeld, JoAnn M. Frank Peacock, W. Sawyer, Douglas M. Teerlink, John R. Butler, Javed |
| spellingShingle |
Collins, Sean P. Levy, Phillip D. Fermann, Gregory J. Givertz, Michael M. Martindale, Jennifer M. Pang, Peter S. Storrow, Alan B. Diercks, Deborah D. Michael Felker, G. Fonarow, Gregg C. Lanfear, David J. Lenihan, Daniel J. Lindenfeld, JoAnn M. Frank Peacock, W. Sawyer, Douglas M. Teerlink, John R. Butler, Javed Academic Emergency Medicine What's Next for Acute Heart Failure Research? Emergency Medicine General Medicine |
| author_sort |
collins, sean p. |
| spelling |
Collins, Sean P. Levy, Phillip D. Fermann, Gregory J. Givertz, Michael M. Martindale, Jennifer M. Pang, Peter S. Storrow, Alan B. Diercks, Deborah D. Michael Felker, G. Fonarow, Gregg C. Lanfear, David J. Lenihan, Daniel J. Lindenfeld, JoAnn M. Frank Peacock, W. Sawyer, Douglas M. Teerlink, John R. Butler, Javed 1069-6563 1553-2712 Wiley Emergency Medicine General Medicine http://dx.doi.org/10.1111/acem.13331 <jats:title>Abstract</jats:title><jats:p>Each year over one million patients with acute heart failure (<jats:styled-content style="fixed-case">AHF</jats:styled-content>) present to a United States emergency department (<jats:styled-content style="fixed-case">ED</jats:styled-content>). The vast majority are hospitalized for further management. The length of stay and high postdischarge event rate in this cohort have changed little over the past decade. Therapeutic trials have failed to yield substantive improvement in postdischarge outcomes; subsequently, <jats:styled-content style="fixed-case">AHF</jats:styled-content> care has changed little in the past 40 years. Prior research studies have been fragmented as either “inpatient” or “<jats:styled-content style="fixed-case">ED</jats:styled-content>‐based.” Recognizing the challenges in identification and enrollment of <jats:styled-content style="fixed-case">ED</jats:styled-content> patients with <jats:styled-content style="fixed-case">AHF</jats:styled-content>, and the lack of robust evidence to guide management, an <jats:styled-content style="fixed-case">AHF</jats:styled-content> clinical trials network was developed. This network has demonstrated, through organized collaboration between cardiology and emergency medicine, that many of the hurdles in <jats:styled-content style="fixed-case">AHF</jats:styled-content> research can be overcome. The development of a network that supports the collaboration of acute care and <jats:styled-content style="fixed-case">HF</jats:styled-content> researchers, combined with the availability of federally funded infrastructure, will facilitate more efficient conduct of both explanatory and pragmatic trials in <jats:styled-content style="fixed-case">AHF</jats:styled-content>. Yet many important questions remain, and in this document our group of emergency medicine and cardiology investigators have identified four high‐priority research areas.</jats:p> What's Next for Acute Heart Failure Research? Academic Emergency Medicine |
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| title |
What's Next for Acute Heart Failure Research? |
| title_unstemmed |
What's Next for Acute Heart Failure Research? |
| title_full |
What's Next for Acute Heart Failure Research? |
| title_fullStr |
What's Next for Acute Heart Failure Research? |
| title_full_unstemmed |
What's Next for Acute Heart Failure Research? |
| title_short |
What's Next for Acute Heart Failure Research? |
| title_sort |
what's next for acute heart failure research? |
| topic |
Emergency Medicine General Medicine |
| url |
http://dx.doi.org/10.1111/acem.13331 |
| publishDate |
2018 |
| physical |
85-93 |
| description |
<jats:title>Abstract</jats:title><jats:p>Each year over one million patients with acute heart failure (<jats:styled-content style="fixed-case">AHF</jats:styled-content>) present to a United States emergency department (<jats:styled-content style="fixed-case">ED</jats:styled-content>). The vast majority are hospitalized for further management. The length of stay and high postdischarge event rate in this cohort have changed little over the past decade. Therapeutic trials have failed to yield substantive improvement in postdischarge outcomes; subsequently, <jats:styled-content style="fixed-case">AHF</jats:styled-content> care has changed little in the past 40 years. Prior research studies have been fragmented as either “inpatient” or “<jats:styled-content style="fixed-case">ED</jats:styled-content>‐based.” Recognizing the challenges in identification and enrollment of <jats:styled-content style="fixed-case">ED</jats:styled-content> patients with <jats:styled-content style="fixed-case">AHF</jats:styled-content>, and the lack of robust evidence to guide management, an <jats:styled-content style="fixed-case">AHF</jats:styled-content> clinical trials network was developed. This network has demonstrated, through organized collaboration between cardiology and emergency medicine, that many of the hurdles in <jats:styled-content style="fixed-case">AHF</jats:styled-content> research can be overcome. The development of a network that supports the collaboration of acute care and <jats:styled-content style="fixed-case">HF</jats:styled-content> researchers, combined with the availability of federally funded infrastructure, will facilitate more efficient conduct of both explanatory and pragmatic trials in <jats:styled-content style="fixed-case">AHF</jats:styled-content>. Yet many important questions remain, and in this document our group of emergency medicine and cardiology investigators have identified four high‐priority research areas.</jats:p> |
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| author | Collins, Sean P., Levy, Phillip D., Fermann, Gregory J., Givertz, Michael M., Martindale, Jennifer M., Pang, Peter S., Storrow, Alan B., Diercks, Deborah D., Michael Felker, G., Fonarow, Gregg C., Lanfear, David J., Lenihan, Daniel J., Lindenfeld, JoAnn M., Frank Peacock, W., Sawyer, Douglas M., Teerlink, John R., Butler, Javed |
| author_facet | Collins, Sean P., Levy, Phillip D., Fermann, Gregory J., Givertz, Michael M., Martindale, Jennifer M., Pang, Peter S., Storrow, Alan B., Diercks, Deborah D., Michael Felker, G., Fonarow, Gregg C., Lanfear, David J., Lenihan, Daniel J., Lindenfeld, JoAnn M., Frank Peacock, W., Sawyer, Douglas M., Teerlink, John R., Butler, Javed, Collins, Sean P., Levy, Phillip D., Fermann, Gregory J., Givertz, Michael M., Martindale, Jennifer M., Pang, Peter S., Storrow, Alan B., Diercks, Deborah D., Michael Felker, G., Fonarow, Gregg C., Lanfear, David J., Lenihan, Daniel J., Lindenfeld, JoAnn M., Frank Peacock, W., Sawyer, Douglas M., Teerlink, John R., Butler, Javed |
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| description | <jats:title>Abstract</jats:title><jats:p>Each year over one million patients with acute heart failure (<jats:styled-content style="fixed-case">AHF</jats:styled-content>) present to a United States emergency department (<jats:styled-content style="fixed-case">ED</jats:styled-content>). The vast majority are hospitalized for further management. The length of stay and high postdischarge event rate in this cohort have changed little over the past decade. Therapeutic trials have failed to yield substantive improvement in postdischarge outcomes; subsequently, <jats:styled-content style="fixed-case">AHF</jats:styled-content> care has changed little in the past 40 years. Prior research studies have been fragmented as either “inpatient” or “<jats:styled-content style="fixed-case">ED</jats:styled-content>‐based.” Recognizing the challenges in identification and enrollment of <jats:styled-content style="fixed-case">ED</jats:styled-content> patients with <jats:styled-content style="fixed-case">AHF</jats:styled-content>, and the lack of robust evidence to guide management, an <jats:styled-content style="fixed-case">AHF</jats:styled-content> clinical trials network was developed. This network has demonstrated, through organized collaboration between cardiology and emergency medicine, that many of the hurdles in <jats:styled-content style="fixed-case">AHF</jats:styled-content> research can be overcome. The development of a network that supports the collaboration of acute care and <jats:styled-content style="fixed-case">HF</jats:styled-content> researchers, combined with the availability of federally funded infrastructure, will facilitate more efficient conduct of both explanatory and pragmatic trials in <jats:styled-content style="fixed-case">AHF</jats:styled-content>. Yet many important questions remain, and in this document our group of emergency medicine and cardiology investigators have identified four high‐priority research areas.</jats:p> |
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| spelling | Collins, Sean P. Levy, Phillip D. Fermann, Gregory J. Givertz, Michael M. Martindale, Jennifer M. Pang, Peter S. Storrow, Alan B. Diercks, Deborah D. Michael Felker, G. Fonarow, Gregg C. Lanfear, David J. Lenihan, Daniel J. Lindenfeld, JoAnn M. Frank Peacock, W. Sawyer, Douglas M. Teerlink, John R. Butler, Javed 1069-6563 1553-2712 Wiley Emergency Medicine General Medicine http://dx.doi.org/10.1111/acem.13331 <jats:title>Abstract</jats:title><jats:p>Each year over one million patients with acute heart failure (<jats:styled-content style="fixed-case">AHF</jats:styled-content>) present to a United States emergency department (<jats:styled-content style="fixed-case">ED</jats:styled-content>). The vast majority are hospitalized for further management. The length of stay and high postdischarge event rate in this cohort have changed little over the past decade. Therapeutic trials have failed to yield substantive improvement in postdischarge outcomes; subsequently, <jats:styled-content style="fixed-case">AHF</jats:styled-content> care has changed little in the past 40 years. Prior research studies have been fragmented as either “inpatient” or “<jats:styled-content style="fixed-case">ED</jats:styled-content>‐based.” Recognizing the challenges in identification and enrollment of <jats:styled-content style="fixed-case">ED</jats:styled-content> patients with <jats:styled-content style="fixed-case">AHF</jats:styled-content>, and the lack of robust evidence to guide management, an <jats:styled-content style="fixed-case">AHF</jats:styled-content> clinical trials network was developed. This network has demonstrated, through organized collaboration between cardiology and emergency medicine, that many of the hurdles in <jats:styled-content style="fixed-case">AHF</jats:styled-content> research can be overcome. The development of a network that supports the collaboration of acute care and <jats:styled-content style="fixed-case">HF</jats:styled-content> researchers, combined with the availability of federally funded infrastructure, will facilitate more efficient conduct of both explanatory and pragmatic trials in <jats:styled-content style="fixed-case">AHF</jats:styled-content>. Yet many important questions remain, and in this document our group of emergency medicine and cardiology investigators have identified four high‐priority research areas.</jats:p> What's Next for Acute Heart Failure Research? Academic Emergency Medicine |
| spellingShingle | Collins, Sean P., Levy, Phillip D., Fermann, Gregory J., Givertz, Michael M., Martindale, Jennifer M., Pang, Peter S., Storrow, Alan B., Diercks, Deborah D., Michael Felker, G., Fonarow, Gregg C., Lanfear, David J., Lenihan, Daniel J., Lindenfeld, JoAnn M., Frank Peacock, W., Sawyer, Douglas M., Teerlink, John R., Butler, Javed, Academic Emergency Medicine, What's Next for Acute Heart Failure Research?, Emergency Medicine, General Medicine |
| title | What's Next for Acute Heart Failure Research? |
| title_full | What's Next for Acute Heart Failure Research? |
| title_fullStr | What's Next for Acute Heart Failure Research? |
| title_full_unstemmed | What's Next for Acute Heart Failure Research? |
| title_short | What's Next for Acute Heart Failure Research? |
| title_sort | what's next for acute heart failure research? |
| title_unstemmed | What's Next for Acute Heart Failure Research? |
| topic | Emergency Medicine, General Medicine |
| url | http://dx.doi.org/10.1111/acem.13331 |