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A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyel...

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Zeitschriftentitel: Global Spine Journal
Personen und Körperschaften: Fehlings, Michael G., Tetreault, Lindsay A., Riew, K. Daniel, Middleton, James W., Aarabi, Bizhan, Arnold, Paul M., Brodke, Darrel S., Burns, Anthony S., Carette, Simon, Chen, Robert, Chiba, Kazuhiro, Dettori, Joseph R., Furlan, Julio C., Harrop, James S., Holly, Langston T., Kalsi-Ryan, Sukhvinder, Kotter, Mark, Kwon, Brian K., Martin, Allan R., Milligan, James, Nakashima, Hiroaki, Nagoshi, Narihito, Rhee, John, Singh, Anoushka, Skelly, Andrea C., Sodhi, Sumeet, Wilson, Jefferson R., Yee, Albert, Wang, Jeffrey C.
In: Global Spine Journal, 7, 2017, 3_suppl, S. 70S-83S
Format: E-Article
Sprache: Englisch
veröffentlicht:
SAGE Publications
Schlagwörter:
author_facet Fehlings, Michael G.
Tetreault, Lindsay A.
Riew, K. Daniel
Middleton, James W.
Aarabi, Bizhan
Arnold, Paul M.
Brodke, Darrel S.
Burns, Anthony S.
Carette, Simon
Chen, Robert
Chiba, Kazuhiro
Dettori, Joseph R.
Furlan, Julio C.
Harrop, James S.
Holly, Langston T.
Kalsi-Ryan, Sukhvinder
Kotter, Mark
Kwon, Brian K.
Martin, Allan R.
Milligan, James
Nakashima, Hiroaki
Nagoshi, Narihito
Rhee, John
Singh, Anoushka
Skelly, Andrea C.
Sodhi, Sumeet
Wilson, Jefferson R.
Yee, Albert
Wang, Jeffrey C.
Fehlings, Michael G.
Tetreault, Lindsay A.
Riew, K. Daniel
Middleton, James W.
Aarabi, Bizhan
Arnold, Paul M.
Brodke, Darrel S.
Burns, Anthony S.
Carette, Simon
Chen, Robert
Chiba, Kazuhiro
Dettori, Joseph R.
Furlan, Julio C.
Harrop, James S.
Holly, Langston T.
Kalsi-Ryan, Sukhvinder
Kotter, Mark
Kwon, Brian K.
Martin, Allan R.
Milligan, James
Nakashima, Hiroaki
Nagoshi, Narihito
Rhee, John
Singh, Anoushka
Skelly, Andrea C.
Sodhi, Sumeet
Wilson, Jefferson R.
Yee, Albert
Wang, Jeffrey C.
author Fehlings, Michael G.
Tetreault, Lindsay A.
Riew, K. Daniel
Middleton, James W.
Aarabi, Bizhan
Arnold, Paul M.
Brodke, Darrel S.
Burns, Anthony S.
Carette, Simon
Chen, Robert
Chiba, Kazuhiro
Dettori, Joseph R.
Furlan, Julio C.
Harrop, James S.
Holly, Langston T.
Kalsi-Ryan, Sukhvinder
Kotter, Mark
Kwon, Brian K.
Martin, Allan R.
Milligan, James
Nakashima, Hiroaki
Nagoshi, Narihito
Rhee, John
Singh, Anoushka
Skelly, Andrea C.
Sodhi, Sumeet
Wilson, Jefferson R.
Yee, Albert
Wang, Jeffrey C.
spellingShingle Fehlings, Michael G.
Tetreault, Lindsay A.
Riew, K. Daniel
Middleton, James W.
Aarabi, Bizhan
Arnold, Paul M.
Brodke, Darrel S.
Burns, Anthony S.
Carette, Simon
Chen, Robert
Chiba, Kazuhiro
Dettori, Joseph R.
Furlan, Julio C.
Harrop, James S.
Holly, Langston T.
Kalsi-Ryan, Sukhvinder
Kotter, Mark
Kwon, Brian K.
Martin, Allan R.
Milligan, James
Nakashima, Hiroaki
Nagoshi, Narihito
Rhee, John
Singh, Anoushka
Skelly, Andrea C.
Sodhi, Sumeet
Wilson, Jefferson R.
Yee, Albert
Wang, Jeffrey C.
Global Spine Journal
A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
Neurology (clinical)
Orthopedics and Sports Medicine
Surgery
author_sort fehlings, michael g.
spelling Fehlings, Michael G. Tetreault, Lindsay A. Riew, K. Daniel Middleton, James W. Aarabi, Bizhan Arnold, Paul M. Brodke, Darrel S. Burns, Anthony S. Carette, Simon Chen, Robert Chiba, Kazuhiro Dettori, Joseph R. Furlan, Julio C. Harrop, James S. Holly, Langston T. Kalsi-Ryan, Sukhvinder Kotter, Mark Kwon, Brian K. Martin, Allan R. Milligan, James Nakashima, Hiroaki Nagoshi, Narihito Rhee, John Singh, Anoushka Skelly, Andrea C. Sodhi, Sumeet Wilson, Jefferson R. Yee, Albert Wang, Jeffrey C. 2192-5682 2192-5690 SAGE Publications Neurology (clinical) Orthopedics and Sports Medicine Surgery http://dx.doi.org/10.1177/2192568217701914 <jats:sec><jats:title>Study Design:</jats:title><jats:p> Guideline development. </jats:p></jats:sec><jats:sec><jats:title>Objectives:</jats:title><jats:p> The objective of this study is to develop guidelines that outline how to best manage (1) patients with mild, moderate, and severe myelopathy and (2) nonmyelopathic patients with evidence of cord compression with or without clinical symptoms of radiculopathy. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> Five systematic reviews of the literature were conducted to synthesize evidence on disease natural history; risk factors of disease progression; the efficacy, effectiveness, and safety of nonoperative and surgical management; the impact of preoperative duration of symptoms and myelopathy severity on treatment outcomes; and the frequency, timing, and predictors of symptom development. A multidisciplinary guideline development group used this information, and their clinical expertise, to develop recommendations for the management of degenerative cervical myelopathy (DCM). </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Our recommendations were as follows: (1) “We recommend surgical intervention for patients with moderate and severe DCM.” (2) “We suggest offering surgical intervention or a supervised trial of structured rehabilitation for patients with mild DCM. If initial nonoperative management is pursued, we recommend operative intervention if there is neurological deterioration and suggest operative intervention if the patient fails to improve.” (3) “We suggest not offering prophylactic surgery for non-myelopathic patients with evidence of cervical cord compression without signs or symptoms of radiculopathy. We suggest that these patients be counseled as to potential risks of progression, educated about relevant signs and symptoms of myelopathy, and be followed clinically.” (4) “Non-myelopathic patients with cord compression and clinical evidence of radiculopathy with or without electrophysiological confirmation are at a higher risk of developing myelopathy and should be counselled about this risk. We suggest offering either surgical intervention or nonoperative treatment consisting of close serial follow-up or a supervised trial of structured rehabilitation. In the event of myelopathic development, the patient should be managed according to the recommendations above.” </jats:p></jats:sec><jats:sec><jats:title>Conclusions:</jats:title><jats:p> These guidelines will promote standardization of care for patients with DCM, decrease the heterogeneity of management strategies and encourage clinicians to make evidence-informed decisions. </jats:p></jats:sec> A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression Global Spine Journal
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series Global Spine Journal
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title A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
title_unstemmed A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
title_full A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
title_fullStr A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
title_full_unstemmed A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
title_short A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
title_sort a clinical practice guideline for the management of patients with degenerative cervical myelopathy: recommendations for patients with mild, moderate, and severe disease and nonmyelopathic patients with evidence of cord compression
topic Neurology (clinical)
Orthopedics and Sports Medicine
Surgery
url http://dx.doi.org/10.1177/2192568217701914
publishDate 2017
physical 70S-83S
description <jats:sec><jats:title>Study Design:</jats:title><jats:p> Guideline development. </jats:p></jats:sec><jats:sec><jats:title>Objectives:</jats:title><jats:p> The objective of this study is to develop guidelines that outline how to best manage (1) patients with mild, moderate, and severe myelopathy and (2) nonmyelopathic patients with evidence of cord compression with or without clinical symptoms of radiculopathy. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> Five systematic reviews of the literature were conducted to synthesize evidence on disease natural history; risk factors of disease progression; the efficacy, effectiveness, and safety of nonoperative and surgical management; the impact of preoperative duration of symptoms and myelopathy severity on treatment outcomes; and the frequency, timing, and predictors of symptom development. A multidisciplinary guideline development group used this information, and their clinical expertise, to develop recommendations for the management of degenerative cervical myelopathy (DCM). </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Our recommendations were as follows: (1) “We recommend surgical intervention for patients with moderate and severe DCM.” (2) “We suggest offering surgical intervention or a supervised trial of structured rehabilitation for patients with mild DCM. If initial nonoperative management is pursued, we recommend operative intervention if there is neurological deterioration and suggest operative intervention if the patient fails to improve.” (3) “We suggest not offering prophylactic surgery for non-myelopathic patients with evidence of cervical cord compression without signs or symptoms of radiculopathy. We suggest that these patients be counseled as to potential risks of progression, educated about relevant signs and symptoms of myelopathy, and be followed clinically.” (4) “Non-myelopathic patients with cord compression and clinical evidence of radiculopathy with or without electrophysiological confirmation are at a higher risk of developing myelopathy and should be counselled about this risk. We suggest offering either surgical intervention or nonoperative treatment consisting of close serial follow-up or a supervised trial of structured rehabilitation. In the event of myelopathic development, the patient should be managed according to the recommendations above.” </jats:p></jats:sec><jats:sec><jats:title>Conclusions:</jats:title><jats:p> These guidelines will promote standardization of care for patients with DCM, decrease the heterogeneity of management strategies and encourage clinicians to make evidence-informed decisions. </jats:p></jats:sec>
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author Fehlings, Michael G., Tetreault, Lindsay A., Riew, K. Daniel, Middleton, James W., Aarabi, Bizhan, Arnold, Paul M., Brodke, Darrel S., Burns, Anthony S., Carette, Simon, Chen, Robert, Chiba, Kazuhiro, Dettori, Joseph R., Furlan, Julio C., Harrop, James S., Holly, Langston T., Kalsi-Ryan, Sukhvinder, Kotter, Mark, Kwon, Brian K., Martin, Allan R., Milligan, James, Nakashima, Hiroaki, Nagoshi, Narihito, Rhee, John, Singh, Anoushka, Skelly, Andrea C., Sodhi, Sumeet, Wilson, Jefferson R., Yee, Albert, Wang, Jeffrey C.
author_facet Fehlings, Michael G., Tetreault, Lindsay A., Riew, K. Daniel, Middleton, James W., Aarabi, Bizhan, Arnold, Paul M., Brodke, Darrel S., Burns, Anthony S., Carette, Simon, Chen, Robert, Chiba, Kazuhiro, Dettori, Joseph R., Furlan, Julio C., Harrop, James S., Holly, Langston T., Kalsi-Ryan, Sukhvinder, Kotter, Mark, Kwon, Brian K., Martin, Allan R., Milligan, James, Nakashima, Hiroaki, Nagoshi, Narihito, Rhee, John, Singh, Anoushka, Skelly, Andrea C., Sodhi, Sumeet, Wilson, Jefferson R., Yee, Albert, Wang, Jeffrey C., Fehlings, Michael G., Tetreault, Lindsay A., Riew, K. Daniel, Middleton, James W., Aarabi, Bizhan, Arnold, Paul M., Brodke, Darrel S., Burns, Anthony S., Carette, Simon, Chen, Robert, Chiba, Kazuhiro, Dettori, Joseph R., Furlan, Julio C., Harrop, James S., Holly, Langston T., Kalsi-Ryan, Sukhvinder, Kotter, Mark, Kwon, Brian K., Martin, Allan R., Milligan, James, Nakashima, Hiroaki, Nagoshi, Narihito, Rhee, John, Singh, Anoushka, Skelly, Andrea C., Sodhi, Sumeet, Wilson, Jefferson R., Yee, Albert, Wang, Jeffrey C.
author_sort fehlings, michael g.
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description <jats:sec><jats:title>Study Design:</jats:title><jats:p> Guideline development. </jats:p></jats:sec><jats:sec><jats:title>Objectives:</jats:title><jats:p> The objective of this study is to develop guidelines that outline how to best manage (1) patients with mild, moderate, and severe myelopathy and (2) nonmyelopathic patients with evidence of cord compression with or without clinical symptoms of radiculopathy. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> Five systematic reviews of the literature were conducted to synthesize evidence on disease natural history; risk factors of disease progression; the efficacy, effectiveness, and safety of nonoperative and surgical management; the impact of preoperative duration of symptoms and myelopathy severity on treatment outcomes; and the frequency, timing, and predictors of symptom development. A multidisciplinary guideline development group used this information, and their clinical expertise, to develop recommendations for the management of degenerative cervical myelopathy (DCM). </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Our recommendations were as follows: (1) “We recommend surgical intervention for patients with moderate and severe DCM.” (2) “We suggest offering surgical intervention or a supervised trial of structured rehabilitation for patients with mild DCM. If initial nonoperative management is pursued, we recommend operative intervention if there is neurological deterioration and suggest operative intervention if the patient fails to improve.” (3) “We suggest not offering prophylactic surgery for non-myelopathic patients with evidence of cervical cord compression without signs or symptoms of radiculopathy. We suggest that these patients be counseled as to potential risks of progression, educated about relevant signs and symptoms of myelopathy, and be followed clinically.” (4) “Non-myelopathic patients with cord compression and clinical evidence of radiculopathy with or without electrophysiological confirmation are at a higher risk of developing myelopathy and should be counselled about this risk. We suggest offering either surgical intervention or nonoperative treatment consisting of close serial follow-up or a supervised trial of structured rehabilitation. In the event of myelopathic development, the patient should be managed according to the recommendations above.” </jats:p></jats:sec><jats:sec><jats:title>Conclusions:</jats:title><jats:p> These guidelines will promote standardization of care for patients with DCM, decrease the heterogeneity of management strategies and encourage clinicians to make evidence-informed decisions. </jats:p></jats:sec>
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spelling Fehlings, Michael G. Tetreault, Lindsay A. Riew, K. Daniel Middleton, James W. Aarabi, Bizhan Arnold, Paul M. Brodke, Darrel S. Burns, Anthony S. Carette, Simon Chen, Robert Chiba, Kazuhiro Dettori, Joseph R. Furlan, Julio C. Harrop, James S. Holly, Langston T. Kalsi-Ryan, Sukhvinder Kotter, Mark Kwon, Brian K. Martin, Allan R. Milligan, James Nakashima, Hiroaki Nagoshi, Narihito Rhee, John Singh, Anoushka Skelly, Andrea C. Sodhi, Sumeet Wilson, Jefferson R. Yee, Albert Wang, Jeffrey C. 2192-5682 2192-5690 SAGE Publications Neurology (clinical) Orthopedics and Sports Medicine Surgery http://dx.doi.org/10.1177/2192568217701914 <jats:sec><jats:title>Study Design:</jats:title><jats:p> Guideline development. </jats:p></jats:sec><jats:sec><jats:title>Objectives:</jats:title><jats:p> The objective of this study is to develop guidelines that outline how to best manage (1) patients with mild, moderate, and severe myelopathy and (2) nonmyelopathic patients with evidence of cord compression with or without clinical symptoms of radiculopathy. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> Five systematic reviews of the literature were conducted to synthesize evidence on disease natural history; risk factors of disease progression; the efficacy, effectiveness, and safety of nonoperative and surgical management; the impact of preoperative duration of symptoms and myelopathy severity on treatment outcomes; and the frequency, timing, and predictors of symptom development. A multidisciplinary guideline development group used this information, and their clinical expertise, to develop recommendations for the management of degenerative cervical myelopathy (DCM). </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Our recommendations were as follows: (1) “We recommend surgical intervention for patients with moderate and severe DCM.” (2) “We suggest offering surgical intervention or a supervised trial of structured rehabilitation for patients with mild DCM. If initial nonoperative management is pursued, we recommend operative intervention if there is neurological deterioration and suggest operative intervention if the patient fails to improve.” (3) “We suggest not offering prophylactic surgery for non-myelopathic patients with evidence of cervical cord compression without signs or symptoms of radiculopathy. We suggest that these patients be counseled as to potential risks of progression, educated about relevant signs and symptoms of myelopathy, and be followed clinically.” (4) “Non-myelopathic patients with cord compression and clinical evidence of radiculopathy with or without electrophysiological confirmation are at a higher risk of developing myelopathy and should be counselled about this risk. We suggest offering either surgical intervention or nonoperative treatment consisting of close serial follow-up or a supervised trial of structured rehabilitation. In the event of myelopathic development, the patient should be managed according to the recommendations above.” </jats:p></jats:sec><jats:sec><jats:title>Conclusions:</jats:title><jats:p> These guidelines will promote standardization of care for patients with DCM, decrease the heterogeneity of management strategies and encourage clinicians to make evidence-informed decisions. </jats:p></jats:sec> A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression Global Spine Journal
spellingShingle Fehlings, Michael G., Tetreault, Lindsay A., Riew, K. Daniel, Middleton, James W., Aarabi, Bizhan, Arnold, Paul M., Brodke, Darrel S., Burns, Anthony S., Carette, Simon, Chen, Robert, Chiba, Kazuhiro, Dettori, Joseph R., Furlan, Julio C., Harrop, James S., Holly, Langston T., Kalsi-Ryan, Sukhvinder, Kotter, Mark, Kwon, Brian K., Martin, Allan R., Milligan, James, Nakashima, Hiroaki, Nagoshi, Narihito, Rhee, John, Singh, Anoushka, Skelly, Andrea C., Sodhi, Sumeet, Wilson, Jefferson R., Yee, Albert, Wang, Jeffrey C., Global Spine Journal, A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression, Neurology (clinical), Orthopedics and Sports Medicine, Surgery
title A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
title_full A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
title_fullStr A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
title_full_unstemmed A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
title_short A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
title_sort a clinical practice guideline for the management of patients with degenerative cervical myelopathy: recommendations for patients with mild, moderate, and severe disease and nonmyelopathic patients with evidence of cord compression
title_unstemmed A Clinical Practice Guideline for the Management of Patients With Degenerative Cervical Myelopathy: Recommendations for Patients With Mild, Moderate, and Severe Disease and Nonmyelopathic Patients With Evidence of Cord Compression
topic Neurology (clinical), Orthopedics and Sports Medicine, Surgery
url http://dx.doi.org/10.1177/2192568217701914