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Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia
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| Zeitschriftentitel: | Natural Product Communications |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Natural Product Communications, 15, 2020, 1, S. 1934578X1989950 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
SAGE Publications
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| Schlagwörter: |
| author_facet |
Liu, Ai-Hua Liu, Li-Hua Liu, Chun-Ying Liu, Ai-Hua Liu, Li-Hua Liu, Chun-Ying |
|---|---|
| author |
Liu, Ai-Hua Liu, Li-Hua Liu, Chun-Ying |
| spellingShingle |
Liu, Ai-Hua Liu, Li-Hua Liu, Chun-Ying Natural Product Communications Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia Complementary and alternative medicine Plant Science Drug Discovery Pharmacology General Medicine |
| author_sort |
liu, ai-hua |
| spelling |
Liu, Ai-Hua Liu, Li-Hua Liu, Chun-Ying 1934-578X 1555-9475 SAGE Publications Complementary and alternative medicine Plant Science Drug Discovery Pharmacology General Medicine http://dx.doi.org/10.1177/1934578x19899505 <jats:p> A new aurone, (2 Z)-2-[(4′-hydroxyphenyl) methylene]-6-methoxy-7-prenyl-3(2 H)-benzofurane (1), together with 6 known compounds (2-7), was isolated from the EtOAc-soluble extract of the seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic methods. All compounds were evaluated for in vitro inhibitory activity against a human colon cancer cell line (SW620). Compounds 1 to 3 showed moderate cytotoxicity against the SW620 cells with IC<jats:sub>50</jats:sub> values ranging from 24.31 to 28.72 μM. Among these compounds, 1 showed higher cytotoxicity against SW620 cells with an IC<jats:sub>50</jats:sub> value of 24.31 μM. </jats:p> Anticolon Cancer Potential of (2<i>Z</i>)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2<i>H</i>)-Benzofurane, a New Aurone From <i>Psoralea corylifolia</i> Natural Product Communications |
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SAGE Publications, 2020 |
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| title |
Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia |
| title_unstemmed |
Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia |
| title_full |
Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia |
| title_fullStr |
Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia |
| title_full_unstemmed |
Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia |
| title_short |
Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia |
| title_sort |
anticolon cancer potential of (2<i>z</i>)-2-[(4′-hydroxyphenyl) methylene]-6-methoxy-7-prenyl-3(2<i>h</i>)-benzofurane, a new aurone from <i>psoralea corylifolia</i> |
| topic |
Complementary and alternative medicine Plant Science Drug Discovery Pharmacology General Medicine |
| url |
http://dx.doi.org/10.1177/1934578x19899505 |
| publishDate |
2020 |
| physical |
1934578X1989950 |
| description |
<jats:p> A new aurone, (2 Z)-2-[(4′-hydroxyphenyl) methylene]-6-methoxy-7-prenyl-3(2 H)-benzofurane (1), together with 6 known compounds (2-7), was isolated from the EtOAc-soluble extract of the seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic methods. All compounds were evaluated for in vitro inhibitory activity against a human colon cancer cell line (SW620). Compounds 1 to 3 showed moderate cytotoxicity against the SW620 cells with IC<jats:sub>50</jats:sub> values ranging from 24.31 to 28.72 μM. Among these compounds, 1 showed higher cytotoxicity against SW620 cells with an IC<jats:sub>50</jats:sub> value of 24.31 μM. </jats:p> |
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| description | <jats:p> A new aurone, (2 Z)-2-[(4′-hydroxyphenyl) methylene]-6-methoxy-7-prenyl-3(2 H)-benzofurane (1), together with 6 known compounds (2-7), was isolated from the EtOAc-soluble extract of the seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic methods. All compounds were evaluated for in vitro inhibitory activity against a human colon cancer cell line (SW620). Compounds 1 to 3 showed moderate cytotoxicity against the SW620 cells with IC<jats:sub>50</jats:sub> values ranging from 24.31 to 28.72 μM. Among these compounds, 1 showed higher cytotoxicity against SW620 cells with an IC<jats:sub>50</jats:sub> value of 24.31 μM. </jats:p> |
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| spelling | Liu, Ai-Hua Liu, Li-Hua Liu, Chun-Ying 1934-578X 1555-9475 SAGE Publications Complementary and alternative medicine Plant Science Drug Discovery Pharmacology General Medicine http://dx.doi.org/10.1177/1934578x19899505 <jats:p> A new aurone, (2 Z)-2-[(4′-hydroxyphenyl) methylene]-6-methoxy-7-prenyl-3(2 H)-benzofurane (1), together with 6 known compounds (2-7), was isolated from the EtOAc-soluble extract of the seeds of Psoralea corylifolia. Their structures were elucidated on the basis of spectroscopic methods. All compounds were evaluated for in vitro inhibitory activity against a human colon cancer cell line (SW620). Compounds 1 to 3 showed moderate cytotoxicity against the SW620 cells with IC<jats:sub>50</jats:sub> values ranging from 24.31 to 28.72 μM. Among these compounds, 1 showed higher cytotoxicity against SW620 cells with an IC<jats:sub>50</jats:sub> value of 24.31 μM. </jats:p> Anticolon Cancer Potential of (2<i>Z</i>)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2<i>H</i>)-Benzofurane, a New Aurone From <i>Psoralea corylifolia</i> Natural Product Communications |
| spellingShingle | Liu, Ai-Hua, Liu, Li-Hua, Liu, Chun-Ying, Natural Product Communications, Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia, Complementary and alternative medicine, Plant Science, Drug Discovery, Pharmacology, General Medicine |
| title | Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia |
| title_full | Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia |
| title_fullStr | Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia |
| title_full_unstemmed | Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia |
| title_short | Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia |
| title_sort | anticolon cancer potential of (2<i>z</i>)-2-[(4′-hydroxyphenyl) methylene]-6-methoxy-7-prenyl-3(2<i>h</i>)-benzofurane, a new aurone from <i>psoralea corylifolia</i> |
| title_unstemmed | Anticolon Cancer Potential of (2Z)-2-[(4′-Hydroxyphenyl) Methylene]-6-Methoxy-7-Prenyl-3(2H)-Benzofurane, a New Aurone From Psoralea corylifolia |
| topic | Complementary and alternative medicine, Plant Science, Drug Discovery, Pharmacology, General Medicine |
| url | http://dx.doi.org/10.1177/1934578x19899505 |