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Apolipoprotein E Allele and Hearing Thresholds in Older Adults
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| Zeitschriftentitel: | American Journal of Alzheimer's Disease & Other Dementiasr |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , |
| In: | American Journal of Alzheimer's Disease & Other Dementiasr, 31, 2016, 1, S. 34-39 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
SAGE Publications
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| Schlagwörter: |
| author_facet |
Mener, David J. Betz, Joshua Yaffe, Kristine Harris, Tamara B. Helzner, Elizabeth P. Satterfield, Suzanne Houston, Denise K. Strotmeyer, Elsa S. Pratt, Sheila R. Simonsick, Eleanor M. Lin, Frank R. Mener, David J. Betz, Joshua Yaffe, Kristine Harris, Tamara B. Helzner, Elizabeth P. Satterfield, Suzanne Houston, Denise K. Strotmeyer, Elsa S. Pratt, Sheila R. Simonsick, Eleanor M. Lin, Frank R. |
|---|---|
| author |
Mener, David J. Betz, Joshua Yaffe, Kristine Harris, Tamara B. Helzner, Elizabeth P. Satterfield, Suzanne Houston, Denise K. Strotmeyer, Elsa S. Pratt, Sheila R. Simonsick, Eleanor M. Lin, Frank R. |
| spellingShingle |
Mener, David J. Betz, Joshua Yaffe, Kristine Harris, Tamara B. Helzner, Elizabeth P. Satterfield, Suzanne Houston, Denise K. Strotmeyer, Elsa S. Pratt, Sheila R. Simonsick, Eleanor M. Lin, Frank R. American Journal of Alzheimer's Disease & Other Dementiasr Apolipoprotein E Allele and Hearing Thresholds in Older Adults Psychiatry and Mental health Geriatrics and Gerontology Clinical Psychology General Neuroscience |
| author_sort |
mener, david j. |
| spelling |
Mener, David J. Betz, Joshua Yaffe, Kristine Harris, Tamara B. Helzner, Elizabeth P. Satterfield, Suzanne Houston, Denise K. Strotmeyer, Elsa S. Pratt, Sheila R. Simonsick, Eleanor M. Lin, Frank R. 1533-3175 1938-2731 SAGE Publications Psychiatry and Mental health Geriatrics and Gerontology Clinical Psychology General Neuroscience http://dx.doi.org/10.1177/1533317514537549 <jats:sec><jats:title>Background:</jats:title><jats:p> Whether apolipoprotein E (APOE) E4 allele status which is associated with an increased risk of cognitive decline is also associated with hearing impairment is unknown. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> We studied 1833 men and women enrolled in the Health, Aging and Body Composition study. Regression models adjusted for demographic and cardiovascular risk factors were used to assess the cross-sectional association of APOE-E4 status with individual pure tone hearing thresholds and the 4-frequency pure tone average (0.5-4 kHz) in the better hearing ear. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Compared to participants with no APOE-E4 alleles, participants with 1 allele had better thresholds at 4.0 kHz (β = −2.72 dB, P = .013) and 8.0 kHz (β = −3.05 kHz, P = .006), and participants with 2 alleles had better hearing thresholds at 1.0 kHz (β = −8.56 dB, P = .021). </jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p> Our results suggest that APOE-E4 allele status may be marginally associated with better hearing thresholds in older adults. </jats:p></jats:sec> Apolipoprotein E Allele and Hearing Thresholds in Older Adults American Journal of Alzheimer's Disease & Other Dementiasr |
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SAGE Publications, 2016 |
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American Journal of Alzheimer's Disease & Other Dementiasr |
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| title |
Apolipoprotein E Allele and Hearing Thresholds in Older Adults |
| title_unstemmed |
Apolipoprotein E Allele and Hearing Thresholds in Older Adults |
| title_full |
Apolipoprotein E Allele and Hearing Thresholds in Older Adults |
| title_fullStr |
Apolipoprotein E Allele and Hearing Thresholds in Older Adults |
| title_full_unstemmed |
Apolipoprotein E Allele and Hearing Thresholds in Older Adults |
| title_short |
Apolipoprotein E Allele and Hearing Thresholds in Older Adults |
| title_sort |
apolipoprotein e allele and hearing thresholds in older adults |
| topic |
Psychiatry and Mental health Geriatrics and Gerontology Clinical Psychology General Neuroscience |
| url |
http://dx.doi.org/10.1177/1533317514537549 |
| publishDate |
2016 |
| physical |
34-39 |
| description |
<jats:sec><jats:title>Background:</jats:title><jats:p> Whether apolipoprotein E (APOE) E4 allele status which is associated with an increased risk of cognitive decline is also associated with hearing impairment is unknown. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> We studied 1833 men and women enrolled in the Health, Aging and Body Composition study. Regression models adjusted for demographic and cardiovascular risk factors were used to assess the cross-sectional association of APOE-E4 status with individual pure tone hearing thresholds and the 4-frequency pure tone average (0.5-4 kHz) in the better hearing ear. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Compared to participants with no APOE-E4 alleles, participants with 1 allele had better thresholds at 4.0 kHz (β = −2.72 dB, P = .013) and 8.0 kHz (β = −3.05 kHz, P = .006), and participants with 2 alleles had better hearing thresholds at 1.0 kHz (β = −8.56 dB, P = .021). </jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p> Our results suggest that APOE-E4 allele status may be marginally associated with better hearing thresholds in older adults. </jats:p></jats:sec> |
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| author | Mener, David J., Betz, Joshua, Yaffe, Kristine, Harris, Tamara B., Helzner, Elizabeth P., Satterfield, Suzanne, Houston, Denise K., Strotmeyer, Elsa S., Pratt, Sheila R., Simonsick, Eleanor M., Lin, Frank R. |
| author_facet | Mener, David J., Betz, Joshua, Yaffe, Kristine, Harris, Tamara B., Helzner, Elizabeth P., Satterfield, Suzanne, Houston, Denise K., Strotmeyer, Elsa S., Pratt, Sheila R., Simonsick, Eleanor M., Lin, Frank R., Mener, David J., Betz, Joshua, Yaffe, Kristine, Harris, Tamara B., Helzner, Elizabeth P., Satterfield, Suzanne, Houston, Denise K., Strotmeyer, Elsa S., Pratt, Sheila R., Simonsick, Eleanor M., Lin, Frank R. |
| author_sort | mener, david j. |
| container_issue | 1 |
| container_start_page | 34 |
| container_title | American Journal of Alzheimer's Disease & Other Dementiasr |
| container_volume | 31 |
| description | <jats:sec><jats:title>Background:</jats:title><jats:p> Whether apolipoprotein E (APOE) E4 allele status which is associated with an increased risk of cognitive decline is also associated with hearing impairment is unknown. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> We studied 1833 men and women enrolled in the Health, Aging and Body Composition study. Regression models adjusted for demographic and cardiovascular risk factors were used to assess the cross-sectional association of APOE-E4 status with individual pure tone hearing thresholds and the 4-frequency pure tone average (0.5-4 kHz) in the better hearing ear. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Compared to participants with no APOE-E4 alleles, participants with 1 allele had better thresholds at 4.0 kHz (β = −2.72 dB, P = .013) and 8.0 kHz (β = −3.05 kHz, P = .006), and participants with 2 alleles had better hearing thresholds at 1.0 kHz (β = −8.56 dB, P = .021). </jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p> Our results suggest that APOE-E4 allele status may be marginally associated with better hearing thresholds in older adults. </jats:p></jats:sec> |
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| imprint_str_mv | SAGE Publications, 2016 |
| institution | DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15 |
| issn | 1533-3175, 1938-2731 |
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| spelling | Mener, David J. Betz, Joshua Yaffe, Kristine Harris, Tamara B. Helzner, Elizabeth P. Satterfield, Suzanne Houston, Denise K. Strotmeyer, Elsa S. Pratt, Sheila R. Simonsick, Eleanor M. Lin, Frank R. 1533-3175 1938-2731 SAGE Publications Psychiatry and Mental health Geriatrics and Gerontology Clinical Psychology General Neuroscience http://dx.doi.org/10.1177/1533317514537549 <jats:sec><jats:title>Background:</jats:title><jats:p> Whether apolipoprotein E (APOE) E4 allele status which is associated with an increased risk of cognitive decline is also associated with hearing impairment is unknown. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> We studied 1833 men and women enrolled in the Health, Aging and Body Composition study. Regression models adjusted for demographic and cardiovascular risk factors were used to assess the cross-sectional association of APOE-E4 status with individual pure tone hearing thresholds and the 4-frequency pure tone average (0.5-4 kHz) in the better hearing ear. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Compared to participants with no APOE-E4 alleles, participants with 1 allele had better thresholds at 4.0 kHz (β = −2.72 dB, P = .013) and 8.0 kHz (β = −3.05 kHz, P = .006), and participants with 2 alleles had better hearing thresholds at 1.0 kHz (β = −8.56 dB, P = .021). </jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p> Our results suggest that APOE-E4 allele status may be marginally associated with better hearing thresholds in older adults. </jats:p></jats:sec> Apolipoprotein E Allele and Hearing Thresholds in Older Adults American Journal of Alzheimer's Disease & Other Dementiasr |
| spellingShingle | Mener, David J., Betz, Joshua, Yaffe, Kristine, Harris, Tamara B., Helzner, Elizabeth P., Satterfield, Suzanne, Houston, Denise K., Strotmeyer, Elsa S., Pratt, Sheila R., Simonsick, Eleanor M., Lin, Frank R., American Journal of Alzheimer's Disease & Other Dementiasr, Apolipoprotein E Allele and Hearing Thresholds in Older Adults, Psychiatry and Mental health, Geriatrics and Gerontology, Clinical Psychology, General Neuroscience |
| title | Apolipoprotein E Allele and Hearing Thresholds in Older Adults |
| title_full | Apolipoprotein E Allele and Hearing Thresholds in Older Adults |
| title_fullStr | Apolipoprotein E Allele and Hearing Thresholds in Older Adults |
| title_full_unstemmed | Apolipoprotein E Allele and Hearing Thresholds in Older Adults |
| title_short | Apolipoprotein E Allele and Hearing Thresholds in Older Adults |
| title_sort | apolipoprotein e allele and hearing thresholds in older adults |
| title_unstemmed | Apolipoprotein E Allele and Hearing Thresholds in Older Adults |
| topic | Psychiatry and Mental health, Geriatrics and Gerontology, Clinical Psychology, General Neuroscience |
| url | http://dx.doi.org/10.1177/1533317514537549 |