author_facet Ni, C
Xu, Y-Y
Zhou, S-H
Wang, S-Q
Ni, C
Xu, Y-Y
Zhou, S-H
Wang, S-Q
author Ni, C
Xu, Y-Y
Zhou, S-H
Wang, S-Q
spellingShingle Ni, C
Xu, Y-Y
Zhou, S-H
Wang, S-Q
Journal of International Medical Research
Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
Biochemistry (medical)
Cell Biology
Biochemistry
General Medicine
author_sort ni, c
spelling Ni, C Xu, Y-Y Zhou, S-H Wang, S-Q 0300-0605 1473-2300 SAGE Publications Biochemistry (medical) Cell Biology Biochemistry General Medicine http://dx.doi.org/10.1177/147323001103900134 <jats:p> Inflammatory myofibroblastic tumour (IMT) and low-grade myofibroblastic sarcoma (LGMS) have similar morphological and immunophenotypic features, but LGMS is more malignant than IMT and the treatment requires a wider surgical margin plus post-operative chemotherapy or radiotherapy. To date, only 28 cases of IMT and two cases of LGMS have been reported in the laryngopharynx. Recent studies have suggested that anaplastic lymphoma kinase (ALK) and cytokeratin are important markers for differentiating between the two tumours. Here, two cases involving different myofibroblastic tumours of the larynx are reported. Based on the histological and immunohistochemical results, case 1 was diagnosed as IMT involving the right arytenoepiglottic fold, while case 2 was diagnosed as LGMS involving the epiglottic–glossal surface. There was no recurrence or metastasis in either case after post-operative follow-up (12 and 14 months, respectively). It is difficult to distinguish IMT from LGMS; both morphological and immunohistological analyses are required. </jats:p> Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review Journal of International Medical Research
doi_str_mv 10.1177/147323001103900134
facet_avail Online
Free
finc_class_facet Biologie
Chemie und Pharmazie
format ElectronicArticle
fullrecord blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8xNDczMjMwMDExMDM5MDAxMzQ
id ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8xNDczMjMwMDExMDM5MDAxMzQ
institution DE-105
DE-14
DE-Ch1
DE-L229
DE-D275
DE-Bn3
DE-Brt1
DE-Zwi2
DE-D161
DE-Gla1
DE-Zi4
DE-15
DE-Pl11
DE-Rs1
imprint SAGE Publications, 2011
imprint_str_mv SAGE Publications, 2011
issn 0300-0605
1473-2300
issn_str_mv 0300-0605
1473-2300
language English
mega_collection SAGE Publications (CrossRef)
match_str ni2011differentialdiagnosisofinflammatorymyofibroblastictumourandlowgrademyofibroblasticsarcomatwocasereportswithaliteraturereview
publishDateSort 2011
publisher SAGE Publications
recordtype ai
record_format ai
series Journal of International Medical Research
source_id 49
title Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
title_unstemmed Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
title_full Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
title_fullStr Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
title_full_unstemmed Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
title_short Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
title_sort differential diagnosis of inflammatory myofibroblastic tumour and low-grade myofibroblastic sarcoma: two case reports with a literature review
topic Biochemistry (medical)
Cell Biology
Biochemistry
General Medicine
url http://dx.doi.org/10.1177/147323001103900134
publishDate 2011
physical 311-320
description <jats:p> Inflammatory myofibroblastic tumour (IMT) and low-grade myofibroblastic sarcoma (LGMS) have similar morphological and immunophenotypic features, but LGMS is more malignant than IMT and the treatment requires a wider surgical margin plus post-operative chemotherapy or radiotherapy. To date, only 28 cases of IMT and two cases of LGMS have been reported in the laryngopharynx. Recent studies have suggested that anaplastic lymphoma kinase (ALK) and cytokeratin are important markers for differentiating between the two tumours. Here, two cases involving different myofibroblastic tumours of the larynx are reported. Based on the histological and immunohistochemical results, case 1 was diagnosed as IMT involving the right arytenoepiglottic fold, while case 2 was diagnosed as LGMS involving the epiglottic–glossal surface. There was no recurrence or metastasis in either case after post-operative follow-up (12 and 14 months, respectively). It is difficult to distinguish IMT from LGMS; both morphological and immunohistological analyses are required. </jats:p>
container_issue 1
container_start_page 311
container_title Journal of International Medical Research
container_volume 39
format_de105 Article, E-Article
format_de14 Article, E-Article
format_de15 Article, E-Article
format_de520 Article, E-Article
format_de540 Article, E-Article
format_dech1 Article, E-Article
format_ded117 Article, E-Article
format_degla1 E-Article
format_del152 Buch
format_del189 Article, E-Article
format_dezi4 Article
format_dezwi2 Article, E-Article
format_finc Article, E-Article
format_nrw Article, E-Article
_version_ 1792334672715317248
geogr_code not assigned
last_indexed 2024-03-01T14:32:23.252Z
geogr_code_person not assigned
openURL url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Differential+Diagnosis+of+Inflammatory+Myofibroblastic+Tumour+and+Low-Grade+Myofibroblastic+Sarcoma%3A+Two+Case+Reports+with+a+Literature+Review&rft.date=2011-02-01&genre=article&issn=1473-2300&volume=39&issue=1&spage=311&epage=320&pages=311-320&jtitle=Journal+of+International+Medical+Research&atitle=Differential+Diagnosis+of+Inflammatory+Myofibroblastic+Tumour+and+Low-Grade+Myofibroblastic+Sarcoma%3A+Two+Case+Reports+with+a+Literature+Review&aulast=Wang&aufirst=S-Q&rft_id=info%3Adoi%2F10.1177%2F147323001103900134&rft.language%5B0%5D=eng
SOLR
_version_ 1792334672715317248
author Ni, C, Xu, Y-Y, Zhou, S-H, Wang, S-Q
author_facet Ni, C, Xu, Y-Y, Zhou, S-H, Wang, S-Q, Ni, C, Xu, Y-Y, Zhou, S-H, Wang, S-Q
author_sort ni, c
container_issue 1
container_start_page 311
container_title Journal of International Medical Research
container_volume 39
description <jats:p> Inflammatory myofibroblastic tumour (IMT) and low-grade myofibroblastic sarcoma (LGMS) have similar morphological and immunophenotypic features, but LGMS is more malignant than IMT and the treatment requires a wider surgical margin plus post-operative chemotherapy or radiotherapy. To date, only 28 cases of IMT and two cases of LGMS have been reported in the laryngopharynx. Recent studies have suggested that anaplastic lymphoma kinase (ALK) and cytokeratin are important markers for differentiating between the two tumours. Here, two cases involving different myofibroblastic tumours of the larynx are reported. Based on the histological and immunohistochemical results, case 1 was diagnosed as IMT involving the right arytenoepiglottic fold, while case 2 was diagnosed as LGMS involving the epiglottic–glossal surface. There was no recurrence or metastasis in either case after post-operative follow-up (12 and 14 months, respectively). It is difficult to distinguish IMT from LGMS; both morphological and immunohistological analyses are required. </jats:p>
doi_str_mv 10.1177/147323001103900134
facet_avail Online, Free
finc_class_facet Biologie, Chemie und Pharmazie
format ElectronicArticle
format_de105 Article, E-Article
format_de14 Article, E-Article
format_de15 Article, E-Article
format_de520 Article, E-Article
format_de540 Article, E-Article
format_dech1 Article, E-Article
format_ded117 Article, E-Article
format_degla1 E-Article
format_del152 Buch
format_del189 Article, E-Article
format_dezi4 Article
format_dezwi2 Article, E-Article
format_finc Article, E-Article
format_nrw Article, E-Article
geogr_code not assigned
geogr_code_person not assigned
id ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8xNDczMjMwMDExMDM5MDAxMzQ
imprint SAGE Publications, 2011
imprint_str_mv SAGE Publications, 2011
institution DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1
issn 0300-0605, 1473-2300
issn_str_mv 0300-0605, 1473-2300
language English
last_indexed 2024-03-01T14:32:23.252Z
match_str ni2011differentialdiagnosisofinflammatorymyofibroblastictumourandlowgrademyofibroblasticsarcomatwocasereportswithaliteraturereview
mega_collection SAGE Publications (CrossRef)
physical 311-320
publishDate 2011
publishDateSort 2011
publisher SAGE Publications
record_format ai
recordtype ai
series Journal of International Medical Research
source_id 49
spelling Ni, C Xu, Y-Y Zhou, S-H Wang, S-Q 0300-0605 1473-2300 SAGE Publications Biochemistry (medical) Cell Biology Biochemistry General Medicine http://dx.doi.org/10.1177/147323001103900134 <jats:p> Inflammatory myofibroblastic tumour (IMT) and low-grade myofibroblastic sarcoma (LGMS) have similar morphological and immunophenotypic features, but LGMS is more malignant than IMT and the treatment requires a wider surgical margin plus post-operative chemotherapy or radiotherapy. To date, only 28 cases of IMT and two cases of LGMS have been reported in the laryngopharynx. Recent studies have suggested that anaplastic lymphoma kinase (ALK) and cytokeratin are important markers for differentiating between the two tumours. Here, two cases involving different myofibroblastic tumours of the larynx are reported. Based on the histological and immunohistochemical results, case 1 was diagnosed as IMT involving the right arytenoepiglottic fold, while case 2 was diagnosed as LGMS involving the epiglottic–glossal surface. There was no recurrence or metastasis in either case after post-operative follow-up (12 and 14 months, respectively). It is difficult to distinguish IMT from LGMS; both morphological and immunohistological analyses are required. </jats:p> Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review Journal of International Medical Research
spellingShingle Ni, C, Xu, Y-Y, Zhou, S-H, Wang, S-Q, Journal of International Medical Research, Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review, Biochemistry (medical), Cell Biology, Biochemistry, General Medicine
title Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
title_full Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
title_fullStr Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
title_full_unstemmed Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
title_short Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
title_sort differential diagnosis of inflammatory myofibroblastic tumour and low-grade myofibroblastic sarcoma: two case reports with a literature review
title_unstemmed Differential Diagnosis of Inflammatory Myofibroblastic Tumour and Low-Grade Myofibroblastic Sarcoma: Two Case Reports with a Literature Review
topic Biochemistry (medical), Cell Biology, Biochemistry, General Medicine
url http://dx.doi.org/10.1177/147323001103900134