Eintrag weiter verarbeiten
Review : The Neurobiology of Stroke Rehabilitation
Gespeichert in:
| Zeitschriftentitel: | The Neuroscientist |
|---|---|
| Personen und Körperschaften: | , |
| In: | The Neuroscientist, 4, 1998, 6, S. 426-434 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
SAGE Publications
|
| Schlagwörter: |
| author_facet |
Small, Steven L. Solodkin, Ana Small, Steven L. Solodkin, Ana |
|---|---|
| author |
Small, Steven L. Solodkin, Ana |
| spellingShingle |
Small, Steven L. Solodkin, Ana The Neuroscientist Review : The Neurobiology of Stroke Rehabilitation Neurology (clinical) General Neuroscience |
| author_sort |
small, steven l. |
| spelling |
Small, Steven L. Solodkin, Ana 1073-8584 1089-4098 SAGE Publications Neurology (clinical) General Neuroscience http://dx.doi.org/10.1177/107385849800400614 <jats:p> Cerebrovascular disease plays a paramount role in mortality and morbidity, and the clinical and basic sci entific study of acute stroke has blossomed, leading both to increased survival and to increasing numbers of people with disabilities from stroke. Neurobiological study of the chronic form of this prevalent neurological disease has lagged behind investigation of the acute illness. This article reviews how and why this situation will change. Four major points are addressed: 1) The anatomical organizations of functional brain systems are less topographically precise than commonly believed. 2) Cortical plasticity exists in adults and takes a number of forms, including unmasking of existing circuits, growth of new synapses via axonal sprouting or dendritic proliferation, and development of compensatory processes. 3) It is possible to manipulate this plasticity with behavioral and pharmacological interventions, and such manipulations can have a beneficial effect on recovery. 4) Functional neuroimaging, particularly the noninvasive method of fMRI, can be used to study in vivo both cerebral plasticity after stroke and the interventions that might influence recovery by affecting this plasticity. Although there is much to be accomplished, the prognosis is extremely good for a neuroscience of stroke rehabilitation. NEUROSCIENTIST 4:426-434, 1998 </jats:p> Review : The Neurobiology of Stroke Rehabilitation The Neuroscientist |
| doi_str_mv |
10.1177/107385849800400614 |
| facet_avail |
Online |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8xMDczODU4NDk4MDA0MDA2MTQ |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8xMDczODU4NDk4MDA0MDA2MTQ |
| institution |
DE-D275 DE-Bn3 DE-Brt1 DE-D161 DE-Zi4 DE-Gla1 DE-15 DE-Pl11 DE-Rs1 DE-14 DE-105 DE-Ch1 DE-L229 |
| imprint |
SAGE Publications, 1998 |
| imprint_str_mv |
SAGE Publications, 1998 |
| issn |
1089-4098 1073-8584 |
| issn_str_mv |
1089-4098 1073-8584 |
| language |
English |
| mega_collection |
SAGE Publications (CrossRef) |
| match_str |
small1998reviewtheneurobiologyofstrokerehabilitation |
| publishDateSort |
1998 |
| publisher |
SAGE Publications |
| recordtype |
ai |
| record_format |
ai |
| series |
The Neuroscientist |
| source_id |
49 |
| title |
Review : The Neurobiology of Stroke Rehabilitation |
| title_unstemmed |
Review : The Neurobiology of Stroke Rehabilitation |
| title_full |
Review : The Neurobiology of Stroke Rehabilitation |
| title_fullStr |
Review : The Neurobiology of Stroke Rehabilitation |
| title_full_unstemmed |
Review : The Neurobiology of Stroke Rehabilitation |
| title_short |
Review : The Neurobiology of Stroke Rehabilitation |
| title_sort |
review : the neurobiology of stroke rehabilitation |
| topic |
Neurology (clinical) General Neuroscience |
| url |
http://dx.doi.org/10.1177/107385849800400614 |
| publishDate |
1998 |
| physical |
426-434 |
| description |
<jats:p> Cerebrovascular disease plays a paramount role in mortality and morbidity, and the clinical and basic sci entific study of acute stroke has blossomed, leading both to increased survival and to increasing numbers of people with disabilities from stroke. Neurobiological study of the chronic form of this prevalent neurological disease has lagged behind investigation of the acute illness. This article reviews how and why this situation will change. Four major points are addressed: 1) The anatomical organizations of functional brain systems are less topographically precise than commonly believed. 2) Cortical plasticity exists in adults and takes a number of forms, including unmasking of existing circuits, growth of new synapses via axonal sprouting or dendritic proliferation, and development of compensatory processes. 3) It is possible to manipulate this plasticity with behavioral and pharmacological interventions, and such manipulations can have a beneficial effect on recovery. 4) Functional neuroimaging, particularly the noninvasive method of fMRI, can be used to study in vivo both cerebral plasticity after stroke and the interventions that might influence recovery by affecting this plasticity. Although there is much to be accomplished, the prognosis is extremely good for a neuroscience of stroke rehabilitation. NEUROSCIENTIST 4:426-434, 1998 </jats:p> |
| container_issue |
6 |
| container_start_page |
426 |
| container_title |
The Neuroscientist |
| container_volume |
4 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792326399167561737 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T12:20:52.455Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Review+%3A+The+Neurobiology+of+Stroke+Rehabilitation&rft.date=1998-11-01&genre=article&issn=1089-4098&volume=4&issue=6&spage=426&epage=434&pages=426-434&jtitle=The+Neuroscientist&atitle=Review+%3A+The+Neurobiology+of+Stroke+Rehabilitation&aulast=Solodkin&aufirst=Ana&rft_id=info%3Adoi%2F10.1177%2F107385849800400614&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792326399167561737 |
| author | Small, Steven L., Solodkin, Ana |
| author_facet | Small, Steven L., Solodkin, Ana, Small, Steven L., Solodkin, Ana |
| author_sort | small, steven l. |
| container_issue | 6 |
| container_start_page | 426 |
| container_title | The Neuroscientist |
| container_volume | 4 |
| description | <jats:p> Cerebrovascular disease plays a paramount role in mortality and morbidity, and the clinical and basic sci entific study of acute stroke has blossomed, leading both to increased survival and to increasing numbers of people with disabilities from stroke. Neurobiological study of the chronic form of this prevalent neurological disease has lagged behind investigation of the acute illness. This article reviews how and why this situation will change. Four major points are addressed: 1) The anatomical organizations of functional brain systems are less topographically precise than commonly believed. 2) Cortical plasticity exists in adults and takes a number of forms, including unmasking of existing circuits, growth of new synapses via axonal sprouting or dendritic proliferation, and development of compensatory processes. 3) It is possible to manipulate this plasticity with behavioral and pharmacological interventions, and such manipulations can have a beneficial effect on recovery. 4) Functional neuroimaging, particularly the noninvasive method of fMRI, can be used to study in vivo both cerebral plasticity after stroke and the interventions that might influence recovery by affecting this plasticity. Although there is much to be accomplished, the prognosis is extremely good for a neuroscience of stroke rehabilitation. NEUROSCIENTIST 4:426-434, 1998 </jats:p> |
| doi_str_mv | 10.1177/107385849800400614 |
| facet_avail | Online |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8xMDczODU4NDk4MDA0MDA2MTQ |
| imprint | SAGE Publications, 1998 |
| imprint_str_mv | SAGE Publications, 1998 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Zi4, DE-Gla1, DE-15, DE-Pl11, DE-Rs1, DE-14, DE-105, DE-Ch1, DE-L229 |
| issn | 1089-4098, 1073-8584 |
| issn_str_mv | 1089-4098, 1073-8584 |
| language | English |
| last_indexed | 2024-03-01T12:20:52.455Z |
| match_str | small1998reviewtheneurobiologyofstrokerehabilitation |
| mega_collection | SAGE Publications (CrossRef) |
| physical | 426-434 |
| publishDate | 1998 |
| publishDateSort | 1998 |
| publisher | SAGE Publications |
| record_format | ai |
| recordtype | ai |
| series | The Neuroscientist |
| source_id | 49 |
| spelling | Small, Steven L. Solodkin, Ana 1073-8584 1089-4098 SAGE Publications Neurology (clinical) General Neuroscience http://dx.doi.org/10.1177/107385849800400614 <jats:p> Cerebrovascular disease plays a paramount role in mortality and morbidity, and the clinical and basic sci entific study of acute stroke has blossomed, leading both to increased survival and to increasing numbers of people with disabilities from stroke. Neurobiological study of the chronic form of this prevalent neurological disease has lagged behind investigation of the acute illness. This article reviews how and why this situation will change. Four major points are addressed: 1) The anatomical organizations of functional brain systems are less topographically precise than commonly believed. 2) Cortical plasticity exists in adults and takes a number of forms, including unmasking of existing circuits, growth of new synapses via axonal sprouting or dendritic proliferation, and development of compensatory processes. 3) It is possible to manipulate this plasticity with behavioral and pharmacological interventions, and such manipulations can have a beneficial effect on recovery. 4) Functional neuroimaging, particularly the noninvasive method of fMRI, can be used to study in vivo both cerebral plasticity after stroke and the interventions that might influence recovery by affecting this plasticity. Although there is much to be accomplished, the prognosis is extremely good for a neuroscience of stroke rehabilitation. NEUROSCIENTIST 4:426-434, 1998 </jats:p> Review : The Neurobiology of Stroke Rehabilitation The Neuroscientist |
| spellingShingle | Small, Steven L., Solodkin, Ana, The Neuroscientist, Review : The Neurobiology of Stroke Rehabilitation, Neurology (clinical), General Neuroscience |
| title | Review : The Neurobiology of Stroke Rehabilitation |
| title_full | Review : The Neurobiology of Stroke Rehabilitation |
| title_fullStr | Review : The Neurobiology of Stroke Rehabilitation |
| title_full_unstemmed | Review : The Neurobiology of Stroke Rehabilitation |
| title_short | Review : The Neurobiology of Stroke Rehabilitation |
| title_sort | review : the neurobiology of stroke rehabilitation |
| title_unstemmed | Review : The Neurobiology of Stroke Rehabilitation |
| topic | Neurology (clinical), General Neuroscience |
| url | http://dx.doi.org/10.1177/107385849800400614 |