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Feline Insular Amyloid: Association with Diabetes Mellitus
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| Zeitschriftentitel: | Veterinary Pathology |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Veterinary Pathology, 18, 1981, 5, S. 621-627 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
SAGE Publications
|
| Schlagwörter: |
| author_facet |
Yano, B. L. Hayden, D. W. Johnson, K. H. Yano, B. L. Hayden, D. W. Johnson, K. H. |
|---|---|
| author |
Yano, B. L. Hayden, D. W. Johnson, K. H. |
| spellingShingle |
Yano, B. L. Hayden, D. W. Johnson, K. H. Veterinary Pathology Feline Insular Amyloid: Association with Diabetes Mellitus General Veterinary |
| author_sort |
yano, b. l. |
| spelling |
Yano, B. L. Hayden, D. W. Johnson, K. H. 0300-9858 1544-2217 SAGE Publications General Veterinary http://dx.doi.org/10.1177/030098588101800507 <jats:p> Of 31 domestic cats with diabetes mellitus, 20 (65%) had amyloid deposits in their pancreatic islets (i.e., insular amyloid). The incidence of insular amyloidosis (p = 0.34) was not significantly different between diabetic and age-matched, non-diabetic cats from our previous study. Diabetic cats, however, had a significantly higher mean percentage of islets with amyloid (p = <.005) and a significantly higher mean percentage of islets with abundant amyloid deposits (p = <005) than did non-diabetic cats. These results suggest that insular amyloidosis and diabetes are causally related and are not simply concurrent diseases associated with aging. Although the specific relationship of insular amyloidosis to the pathogenesis of diabetes mellitus was not determined, a functional islet cell abnormality probably precedes the diabetic state and the deposition of insular amyloid. </jats:p> Feline Insular Amyloid: Association with Diabetes Mellitus Veterinary Pathology |
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SAGE Publications, 1981 |
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SAGE Publications, 1981 |
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1981 |
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SAGE Publications |
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Veterinary Pathology |
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49 |
| title |
Feline Insular Amyloid: Association with Diabetes Mellitus |
| title_unstemmed |
Feline Insular Amyloid: Association with Diabetes Mellitus |
| title_full |
Feline Insular Amyloid: Association with Diabetes Mellitus |
| title_fullStr |
Feline Insular Amyloid: Association with Diabetes Mellitus |
| title_full_unstemmed |
Feline Insular Amyloid: Association with Diabetes Mellitus |
| title_short |
Feline Insular Amyloid: Association with Diabetes Mellitus |
| title_sort |
feline insular amyloid: association with diabetes mellitus |
| topic |
General Veterinary |
| url |
http://dx.doi.org/10.1177/030098588101800507 |
| publishDate |
1981 |
| physical |
621-627 |
| description |
<jats:p> Of 31 domestic cats with diabetes mellitus, 20 (65%) had amyloid deposits in their pancreatic islets (i.e., insular amyloid). The incidence of insular amyloidosis (p = 0.34) was not significantly different between diabetic and age-matched, non-diabetic cats from our previous study. Diabetic cats, however, had a significantly higher mean percentage of islets with amyloid (p = <.005) and a significantly higher mean percentage of islets with abundant amyloid deposits (p = <005) than did non-diabetic cats. These results suggest that insular amyloidosis and diabetes are causally related and are not simply concurrent diseases associated with aging. Although the specific relationship of insular amyloidosis to the pathogenesis of diabetes mellitus was not determined, a functional islet cell abnormality probably precedes the diabetic state and the deposition of insular amyloid. </jats:p> |
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| author | Yano, B. L., Hayden, D. W., Johnson, K. H. |
| author_facet | Yano, B. L., Hayden, D. W., Johnson, K. H., Yano, B. L., Hayden, D. W., Johnson, K. H. |
| author_sort | yano, b. l. |
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| container_start_page | 621 |
| container_title | Veterinary Pathology |
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| description | <jats:p> Of 31 domestic cats with diabetes mellitus, 20 (65%) had amyloid deposits in their pancreatic islets (i.e., insular amyloid). The incidence of insular amyloidosis (p = 0.34) was not significantly different between diabetic and age-matched, non-diabetic cats from our previous study. Diabetic cats, however, had a significantly higher mean percentage of islets with amyloid (p = <.005) and a significantly higher mean percentage of islets with abundant amyloid deposits (p = <005) than did non-diabetic cats. These results suggest that insular amyloidosis and diabetes are causally related and are not simply concurrent diseases associated with aging. Although the specific relationship of insular amyloidosis to the pathogenesis of diabetes mellitus was not determined, a functional islet cell abnormality probably precedes the diabetic state and the deposition of insular amyloid. </jats:p> |
| doi_str_mv | 10.1177/030098588101800507 |
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| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8wMzAwOTg1ODgxMDE4MDA1MDc |
| imprint | SAGE Publications, 1981 |
| imprint_str_mv | SAGE Publications, 1981 |
| institution | DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1 |
| issn | 0300-9858, 1544-2217 |
| issn_str_mv | 0300-9858, 1544-2217 |
| language | English |
| last_indexed | 2024-03-01T15:09:54.452Z |
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| physical | 621-627 |
| publishDate | 1981 |
| publishDateSort | 1981 |
| publisher | SAGE Publications |
| record_format | ai |
| recordtype | ai |
| series | Veterinary Pathology |
| source_id | 49 |
| spelling | Yano, B. L. Hayden, D. W. Johnson, K. H. 0300-9858 1544-2217 SAGE Publications General Veterinary http://dx.doi.org/10.1177/030098588101800507 <jats:p> Of 31 domestic cats with diabetes mellitus, 20 (65%) had amyloid deposits in their pancreatic islets (i.e., insular amyloid). The incidence of insular amyloidosis (p = 0.34) was not significantly different between diabetic and age-matched, non-diabetic cats from our previous study. Diabetic cats, however, had a significantly higher mean percentage of islets with amyloid (p = <.005) and a significantly higher mean percentage of islets with abundant amyloid deposits (p = <005) than did non-diabetic cats. These results suggest that insular amyloidosis and diabetes are causally related and are not simply concurrent diseases associated with aging. Although the specific relationship of insular amyloidosis to the pathogenesis of diabetes mellitus was not determined, a functional islet cell abnormality probably precedes the diabetic state and the deposition of insular amyloid. </jats:p> Feline Insular Amyloid: Association with Diabetes Mellitus Veterinary Pathology |
| spellingShingle | Yano, B. L., Hayden, D. W., Johnson, K. H., Veterinary Pathology, Feline Insular Amyloid: Association with Diabetes Mellitus, General Veterinary |
| title | Feline Insular Amyloid: Association with Diabetes Mellitus |
| title_full | Feline Insular Amyloid: Association with Diabetes Mellitus |
| title_fullStr | Feline Insular Amyloid: Association with Diabetes Mellitus |
| title_full_unstemmed | Feline Insular Amyloid: Association with Diabetes Mellitus |
| title_short | Feline Insular Amyloid: Association with Diabetes Mellitus |
| title_sort | feline insular amyloid: association with diabetes mellitus |
| title_unstemmed | Feline Insular Amyloid: Association with Diabetes Mellitus |
| topic | General Veterinary |
| url | http://dx.doi.org/10.1177/030098588101800507 |