Eintrag weiter verarbeiten
Evaluation of plasma endothelial microparticles in pre-eclampsia
Gespeichert in:
| Zeitschriftentitel: | Journal of International Medical Research |
|---|---|
| Personen und Körperschaften: | , , , , , |
| In: | Journal of International Medical Research, 42, 2014, 1, S. 42-51 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
SAGE Publications
|
| Schlagwörter: |
| author_facet |
Ling, Li Huang, Huaping Zhu, Lingyun Mao, Ting Shen, Qian Zhang, Hong Ling, Li Huang, Huaping Zhu, Lingyun Mao, Ting Shen, Qian Zhang, Hong |
|---|---|
| author |
Ling, Li Huang, Huaping Zhu, Lingyun Mao, Ting Shen, Qian Zhang, Hong |
| spellingShingle |
Ling, Li Huang, Huaping Zhu, Lingyun Mao, Ting Shen, Qian Zhang, Hong Journal of International Medical Research Evaluation of plasma endothelial microparticles in pre-eclampsia Biochemistry (medical) Cell Biology Biochemistry General Medicine |
| author_sort |
ling, li |
| spelling |
Ling, Li Huang, Huaping Zhu, Lingyun Mao, Ting Shen, Qian Zhang, Hong 0300-0605 1473-2300 SAGE Publications Biochemistry (medical) Cell Biology Biochemistry General Medicine http://dx.doi.org/10.1177/0300060513504362 <jats:sec><jats:title>Objective</jats:title><jats:p> To compare the antepartum and postpartum plasma concentrations of endothelial microparticles (EMPs) in patients with pre-eclampsia with those of healthy control subjects with normal pregnancies. </jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p> Plasma concentrations of EMPs were measured using specific antibody labelling and flow cytometry prior to delivery by caesarean section (antepartum), and again at 24 h and 72 h postpartum. The correlations between EMP concentration and mean arterial pressure (MAP), and between EMP concentration and 24-h urine protein were analysed. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> A total of 59 patients with pre-eclampsia and 60 healthy control subjects participated in the study. The antepartum plasma EMP concentration was significantly higher in patients with pre-eclampsia than in healthy control subjects with normal pregnancies (2863.5 ± 1543.1 versus 1703.0 ± 592.2 EMPs/ml, respectively); similar findings were observed at 24 h postpartum (1836.7 ± 1153.8 versus 1421.8 ± 760.2 EMPs/ml, respectively). There was no significant difference between the two groups at 72 h postpartum. The antepartum plasma EMP concentration in patients with pre-eclampsia demonstrated a significant positive correlation with MAP ( r = 0.716) and with 24-h urine protein ( r = 0.770). </jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p> Plasma EMP concentration might serve as a biomarker to evaluate the severity of pre-eclampsia in the future. </jats:p></jats:sec> Evaluation of plasma endothelial microparticles in pre-eclampsia Journal of International Medical Research |
| doi_str_mv |
10.1177/0300060513504362 |
| facet_avail |
Online Free |
| finc_class_facet |
Biologie Chemie und Pharmazie |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8wMzAwMDYwNTEzNTA0MzYy |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8wMzAwMDYwNTEzNTA0MzYy |
| institution |
DE-Rs1 DE-Pl11 DE-105 DE-14 DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 DE-15 |
| imprint |
SAGE Publications, 2014 |
| imprint_str_mv |
SAGE Publications, 2014 |
| issn |
0300-0605 1473-2300 |
| issn_str_mv |
0300-0605 1473-2300 |
| language |
English |
| mega_collection |
SAGE Publications (CrossRef) |
| match_str |
ling2014evaluationofplasmaendothelialmicroparticlesinpreeclampsia |
| publishDateSort |
2014 |
| publisher |
SAGE Publications |
| recordtype |
ai |
| record_format |
ai |
| series |
Journal of International Medical Research |
| source_id |
49 |
| title |
Evaluation of plasma endothelial microparticles in pre-eclampsia |
| title_unstemmed |
Evaluation of plasma endothelial microparticles in pre-eclampsia |
| title_full |
Evaluation of plasma endothelial microparticles in pre-eclampsia |
| title_fullStr |
Evaluation of plasma endothelial microparticles in pre-eclampsia |
| title_full_unstemmed |
Evaluation of plasma endothelial microparticles in pre-eclampsia |
| title_short |
Evaluation of plasma endothelial microparticles in pre-eclampsia |
| title_sort |
evaluation of plasma endothelial microparticles in pre-eclampsia |
| topic |
Biochemistry (medical) Cell Biology Biochemistry General Medicine |
| url |
http://dx.doi.org/10.1177/0300060513504362 |
| publishDate |
2014 |
| physical |
42-51 |
| description |
<jats:sec><jats:title>Objective</jats:title><jats:p> To compare the antepartum and postpartum plasma concentrations of endothelial microparticles (EMPs) in patients with pre-eclampsia with those of healthy control subjects with normal pregnancies. </jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p> Plasma concentrations of EMPs were measured using specific antibody labelling and flow cytometry prior to delivery by caesarean section (antepartum), and again at 24 h and 72 h postpartum. The correlations between EMP concentration and mean arterial pressure (MAP), and between EMP concentration and 24-h urine protein were analysed. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> A total of 59 patients with pre-eclampsia and 60 healthy control subjects participated in the study. The antepartum plasma EMP concentration was significantly higher in patients with pre-eclampsia than in healthy control subjects with normal pregnancies (2863.5 ± 1543.1 versus 1703.0 ± 592.2 EMPs/ml, respectively); similar findings were observed at 24 h postpartum (1836.7 ± 1153.8 versus 1421.8 ± 760.2 EMPs/ml, respectively). There was no significant difference between the two groups at 72 h postpartum. The antepartum plasma EMP concentration in patients with pre-eclampsia demonstrated a significant positive correlation with MAP ( r = 0.716) and with 24-h urine protein ( r = 0.770). </jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p> Plasma EMP concentration might serve as a biomarker to evaluate the severity of pre-eclampsia in the future. </jats:p></jats:sec> |
| container_issue |
1 |
| container_start_page |
42 |
| container_title |
Journal of International Medical Research |
| container_volume |
42 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792340290661515264 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T16:01:40.678Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Evaluation+of+plasma+endothelial+microparticles+in+pre-eclampsia&rft.date=2014-02-01&genre=article&issn=1473-2300&volume=42&issue=1&spage=42&epage=51&pages=42-51&jtitle=Journal+of+International+Medical+Research&atitle=Evaluation+of+plasma+endothelial+microparticles+in+pre-eclampsia&aulast=Zhang&aufirst=Hong&rft_id=info%3Adoi%2F10.1177%2F0300060513504362&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792340290661515264 |
| author | Ling, Li, Huang, Huaping, Zhu, Lingyun, Mao, Ting, Shen, Qian, Zhang, Hong |
| author_facet | Ling, Li, Huang, Huaping, Zhu, Lingyun, Mao, Ting, Shen, Qian, Zhang, Hong, Ling, Li, Huang, Huaping, Zhu, Lingyun, Mao, Ting, Shen, Qian, Zhang, Hong |
| author_sort | ling, li |
| container_issue | 1 |
| container_start_page | 42 |
| container_title | Journal of International Medical Research |
| container_volume | 42 |
| description | <jats:sec><jats:title>Objective</jats:title><jats:p> To compare the antepartum and postpartum plasma concentrations of endothelial microparticles (EMPs) in patients with pre-eclampsia with those of healthy control subjects with normal pregnancies. </jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p> Plasma concentrations of EMPs were measured using specific antibody labelling and flow cytometry prior to delivery by caesarean section (antepartum), and again at 24 h and 72 h postpartum. The correlations between EMP concentration and mean arterial pressure (MAP), and between EMP concentration and 24-h urine protein were analysed. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> A total of 59 patients with pre-eclampsia and 60 healthy control subjects participated in the study. The antepartum plasma EMP concentration was significantly higher in patients with pre-eclampsia than in healthy control subjects with normal pregnancies (2863.5 ± 1543.1 versus 1703.0 ± 592.2 EMPs/ml, respectively); similar findings were observed at 24 h postpartum (1836.7 ± 1153.8 versus 1421.8 ± 760.2 EMPs/ml, respectively). There was no significant difference between the two groups at 72 h postpartum. The antepartum plasma EMP concentration in patients with pre-eclampsia demonstrated a significant positive correlation with MAP ( r = 0.716) and with 24-h urine protein ( r = 0.770). </jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p> Plasma EMP concentration might serve as a biomarker to evaluate the severity of pre-eclampsia in the future. </jats:p></jats:sec> |
| doi_str_mv | 10.1177/0300060513504362 |
| facet_avail | Online, Free |
| finc_class_facet | Biologie, Chemie und Pharmazie |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8wMzAwMDYwNTEzNTA0MzYy |
| imprint | SAGE Publications, 2014 |
| imprint_str_mv | SAGE Publications, 2014 |
| institution | DE-Rs1, DE-Pl11, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15 |
| issn | 0300-0605, 1473-2300 |
| issn_str_mv | 0300-0605, 1473-2300 |
| language | English |
| last_indexed | 2024-03-01T16:01:40.678Z |
| match_str | ling2014evaluationofplasmaendothelialmicroparticlesinpreeclampsia |
| mega_collection | SAGE Publications (CrossRef) |
| physical | 42-51 |
| publishDate | 2014 |
| publishDateSort | 2014 |
| publisher | SAGE Publications |
| record_format | ai |
| recordtype | ai |
| series | Journal of International Medical Research |
| source_id | 49 |
| spelling | Ling, Li Huang, Huaping Zhu, Lingyun Mao, Ting Shen, Qian Zhang, Hong 0300-0605 1473-2300 SAGE Publications Biochemistry (medical) Cell Biology Biochemistry General Medicine http://dx.doi.org/10.1177/0300060513504362 <jats:sec><jats:title>Objective</jats:title><jats:p> To compare the antepartum and postpartum plasma concentrations of endothelial microparticles (EMPs) in patients with pre-eclampsia with those of healthy control subjects with normal pregnancies. </jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p> Plasma concentrations of EMPs were measured using specific antibody labelling and flow cytometry prior to delivery by caesarean section (antepartum), and again at 24 h and 72 h postpartum. The correlations between EMP concentration and mean arterial pressure (MAP), and between EMP concentration and 24-h urine protein were analysed. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> A total of 59 patients with pre-eclampsia and 60 healthy control subjects participated in the study. The antepartum plasma EMP concentration was significantly higher in patients with pre-eclampsia than in healthy control subjects with normal pregnancies (2863.5 ± 1543.1 versus 1703.0 ± 592.2 EMPs/ml, respectively); similar findings were observed at 24 h postpartum (1836.7 ± 1153.8 versus 1421.8 ± 760.2 EMPs/ml, respectively). There was no significant difference between the two groups at 72 h postpartum. The antepartum plasma EMP concentration in patients with pre-eclampsia demonstrated a significant positive correlation with MAP ( r = 0.716) and with 24-h urine protein ( r = 0.770). </jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p> Plasma EMP concentration might serve as a biomarker to evaluate the severity of pre-eclampsia in the future. </jats:p></jats:sec> Evaluation of plasma endothelial microparticles in pre-eclampsia Journal of International Medical Research |
| spellingShingle | Ling, Li, Huang, Huaping, Zhu, Lingyun, Mao, Ting, Shen, Qian, Zhang, Hong, Journal of International Medical Research, Evaluation of plasma endothelial microparticles in pre-eclampsia, Biochemistry (medical), Cell Biology, Biochemistry, General Medicine |
| title | Evaluation of plasma endothelial microparticles in pre-eclampsia |
| title_full | Evaluation of plasma endothelial microparticles in pre-eclampsia |
| title_fullStr | Evaluation of plasma endothelial microparticles in pre-eclampsia |
| title_full_unstemmed | Evaluation of plasma endothelial microparticles in pre-eclampsia |
| title_short | Evaluation of plasma endothelial microparticles in pre-eclampsia |
| title_sort | evaluation of plasma endothelial microparticles in pre-eclampsia |
| title_unstemmed | Evaluation of plasma endothelial microparticles in pre-eclampsia |
| topic | Biochemistry (medical), Cell Biology, Biochemistry, General Medicine |
| url | http://dx.doi.org/10.1177/0300060513504362 |