Eintrag weiter verarbeiten
Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis
Gespeichert in:
| Zeitschriftentitel: | Ear, Nose & Throat Journal |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , |
| In: | Ear, Nose & Throat Journal, 101, 2022, 9, S. NP412-NP421 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
SAGE Publications
|
| Schlagwörter: |
| author_facet |
Qiu, Yue Li, Xiaodan Zhang, Xin Wang, Wei Chen, Jun Liu, Yali Fang, Xiaolian Ni, Xin Zhang, Jie Wang, Shengcai Tai, Jun Qiu, Yue Li, Xiaodan Zhang, Xin Wang, Wei Chen, Jun Liu, Yali Fang, Xiaolian Ni, Xin Zhang, Jie Wang, Shengcai Tai, Jun |
|---|---|
| author |
Qiu, Yue Li, Xiaodan Zhang, Xin Wang, Wei Chen, Jun Liu, Yali Fang, Xiaolian Ni, Xin Zhang, Jie Wang, Shengcai Tai, Jun |
| spellingShingle |
Qiu, Yue Li, Xiaodan Zhang, Xin Wang, Wei Chen, Jun Liu, Yali Fang, Xiaolian Ni, Xin Zhang, Jie Wang, Shengcai Tai, Jun Ear, Nose & Throat Journal Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis Otorhinolaryngology |
| author_sort |
qiu, yue |
| spelling |
Qiu, Yue Li, Xiaodan Zhang, Xin Wang, Wei Chen, Jun Liu, Yali Fang, Xiaolian Ni, Xin Zhang, Jie Wang, Shengcai Tai, Jun 0145-5613 1942-7522 SAGE Publications Otorhinolaryngology http://dx.doi.org/10.1177/0145561320965208 <jats:sec><jats:title>Background:</jats:title><jats:p> Previous studies revealed that the prothrombotic factors in patients with obstructive sleep apnea (OSA) remain controversial. </jats:p></jats:sec><jats:sec><jats:title>Aim/Objective:</jats:title><jats:p> The aim of the systematic review is to elucidate the relationship between prothrombotic factors and OSA. </jats:p></jats:sec><jats:sec><jats:title>Materials and Methods:</jats:title><jats:p> This systematic review was performed under the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The literature we investigated was extracted from 4 main medical databases (PubMed, Web of Science, Cochrane Library, and Chinese databases) as of February 2020. We used significant weighted mean differences (SMDs) with 95% CIs from random-effects model. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> A total of 15 studies comprising 2190 patients were available for the meta-analysis. The pooled results showed that the levels of fibrinogen (SMD = 0.95, 95% CI = 0.26 to 1.65, P = .000), vascular endothelial growth factor (SMD = 0.37, 95% CI = −0.90 to 1.63, P = .000), and plasminogen activator inhibitor 1 (SMD = 0.61, 95% CI = 0.29 to 0.92, P = .040) increased in patients with OSA. There were no statistical differences between groups in terms of d-dimer ( P = .108) and platelet counts ( P = .233). Subgroup analyses demonstrated that specimen types and age could account for the heterogeneity. </jats:p></jats:sec><jats:sec><jats:title>Conclusions and Significance:</jats:title><jats:p> This meta-analysis indicated the relationship between prothrombotic factors in OSA hypopnea. Obstructive sleep apnea–related effects may underline the importance of considering the dysfunction of the hemostatic system. The prothrombotic factors in OSA can influence making a choice of appropriate therapy. </jats:p></jats:sec> Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis Ear, Nose & Throat Journal |
| doi_str_mv |
10.1177/0145561320965208 |
| facet_avail |
Online Free |
| finc_class_facet |
Medizin |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8wMTQ1NTYxMzIwOTY1MjA4 |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8wMTQ1NTYxMzIwOTY1MjA4 |
| institution |
DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 |
| imprint |
SAGE Publications, 2022 |
| imprint_str_mv |
SAGE Publications, 2022 |
| issn |
0145-5613 1942-7522 |
| issn_str_mv |
0145-5613 1942-7522 |
| language |
English |
| mega_collection |
SAGE Publications (CrossRef) |
| match_str |
qiu2022prothromboticfactorsinobstructivesleepapneaasystematicreviewwithmetaanalysis |
| publishDateSort |
2022 |
| publisher |
SAGE Publications |
| recordtype |
ai |
| record_format |
ai |
| series |
Ear, Nose & Throat Journal |
| source_id |
49 |
| title |
Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis |
| title_unstemmed |
Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis |
| title_full |
Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis |
| title_fullStr |
Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis |
| title_full_unstemmed |
Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis |
| title_short |
Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis |
| title_sort |
prothrombotic factors in obstructive sleep apnea: a systematic review with meta-analysis |
| topic |
Otorhinolaryngology |
| url |
http://dx.doi.org/10.1177/0145561320965208 |
| publishDate |
2022 |
| physical |
NP412-NP421 |
| description |
<jats:sec><jats:title>Background:</jats:title><jats:p> Previous studies revealed that the prothrombotic factors in patients with obstructive sleep apnea (OSA) remain controversial. </jats:p></jats:sec><jats:sec><jats:title>Aim/Objective:</jats:title><jats:p> The aim of the systematic review is to elucidate the relationship between prothrombotic factors and OSA. </jats:p></jats:sec><jats:sec><jats:title>Materials and Methods:</jats:title><jats:p> This systematic review was performed under the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The literature we investigated was extracted from 4 main medical databases (PubMed, Web of Science, Cochrane Library, and Chinese databases) as of February 2020. We used significant weighted mean differences (SMDs) with 95% CIs from random-effects model. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> A total of 15 studies comprising 2190 patients were available for the meta-analysis. The pooled results showed that the levels of fibrinogen (SMD = 0.95, 95% CI = 0.26 to 1.65, P = .000), vascular endothelial growth factor (SMD = 0.37, 95% CI = −0.90 to 1.63, P = .000), and plasminogen activator inhibitor 1 (SMD = 0.61, 95% CI = 0.29 to 0.92, P = .040) increased in patients with OSA. There were no statistical differences between groups in terms of d-dimer ( P = .108) and platelet counts ( P = .233). Subgroup analyses demonstrated that specimen types and age could account for the heterogeneity. </jats:p></jats:sec><jats:sec><jats:title>Conclusions and Significance:</jats:title><jats:p> This meta-analysis indicated the relationship between prothrombotic factors in OSA hypopnea. Obstructive sleep apnea–related effects may underline the importance of considering the dysfunction of the hemostatic system. The prothrombotic factors in OSA can influence making a choice of appropriate therapy. </jats:p></jats:sec> |
| container_issue |
9 |
| container_start_page |
0 |
| container_title |
Ear, Nose & Throat Journal |
| container_volume |
101 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792328970134355968 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T13:01:45.31Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Prothrombotic+Factors+in+Obstructive+Sleep+Apnea%3A+A+Systematic+Review+With+Meta-Analysis&rft.date=2022-11-01&genre=article&issn=1942-7522&volume=101&issue=9&pages=NP412-NP421&jtitle=Ear%2C+Nose+%26+Throat+Journal&atitle=Prothrombotic+Factors+in+Obstructive+Sleep+Apnea%3A+A+Systematic+Review+With+Meta-Analysis&aulast=Tai&aufirst=Jun&rft_id=info%3Adoi%2F10.1177%2F0145561320965208&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792328970134355968 |
| author | Qiu, Yue, Li, Xiaodan, Zhang, Xin, Wang, Wei, Chen, Jun, Liu, Yali, Fang, Xiaolian, Ni, Xin, Zhang, Jie, Wang, Shengcai, Tai, Jun |
| author_facet | Qiu, Yue, Li, Xiaodan, Zhang, Xin, Wang, Wei, Chen, Jun, Liu, Yali, Fang, Xiaolian, Ni, Xin, Zhang, Jie, Wang, Shengcai, Tai, Jun, Qiu, Yue, Li, Xiaodan, Zhang, Xin, Wang, Wei, Chen, Jun, Liu, Yali, Fang, Xiaolian, Ni, Xin, Zhang, Jie, Wang, Shengcai, Tai, Jun |
| author_sort | qiu, yue |
| container_issue | 9 |
| container_start_page | 0 |
| container_title | Ear, Nose & Throat Journal |
| container_volume | 101 |
| description | <jats:sec><jats:title>Background:</jats:title><jats:p> Previous studies revealed that the prothrombotic factors in patients with obstructive sleep apnea (OSA) remain controversial. </jats:p></jats:sec><jats:sec><jats:title>Aim/Objective:</jats:title><jats:p> The aim of the systematic review is to elucidate the relationship between prothrombotic factors and OSA. </jats:p></jats:sec><jats:sec><jats:title>Materials and Methods:</jats:title><jats:p> This systematic review was performed under the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The literature we investigated was extracted from 4 main medical databases (PubMed, Web of Science, Cochrane Library, and Chinese databases) as of February 2020. We used significant weighted mean differences (SMDs) with 95% CIs from random-effects model. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> A total of 15 studies comprising 2190 patients were available for the meta-analysis. The pooled results showed that the levels of fibrinogen (SMD = 0.95, 95% CI = 0.26 to 1.65, P = .000), vascular endothelial growth factor (SMD = 0.37, 95% CI = −0.90 to 1.63, P = .000), and plasminogen activator inhibitor 1 (SMD = 0.61, 95% CI = 0.29 to 0.92, P = .040) increased in patients with OSA. There were no statistical differences between groups in terms of d-dimer ( P = .108) and platelet counts ( P = .233). Subgroup analyses demonstrated that specimen types and age could account for the heterogeneity. </jats:p></jats:sec><jats:sec><jats:title>Conclusions and Significance:</jats:title><jats:p> This meta-analysis indicated the relationship between prothrombotic factors in OSA hypopnea. Obstructive sleep apnea–related effects may underline the importance of considering the dysfunction of the hemostatic system. The prothrombotic factors in OSA can influence making a choice of appropriate therapy. </jats:p></jats:sec> |
| doi_str_mv | 10.1177/0145561320965208 |
| facet_avail | Online, Free |
| finc_class_facet | Medizin |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE3Ny8wMTQ1NTYxMzIwOTY1MjA4 |
| imprint | SAGE Publications, 2022 |
| imprint_str_mv | SAGE Publications, 2022 |
| institution | DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4 |
| issn | 0145-5613, 1942-7522 |
| issn_str_mv | 0145-5613, 1942-7522 |
| language | English |
| last_indexed | 2024-03-01T13:01:45.31Z |
| match_str | qiu2022prothromboticfactorsinobstructivesleepapneaasystematicreviewwithmetaanalysis |
| mega_collection | SAGE Publications (CrossRef) |
| physical | NP412-NP421 |
| publishDate | 2022 |
| publishDateSort | 2022 |
| publisher | SAGE Publications |
| record_format | ai |
| recordtype | ai |
| series | Ear, Nose & Throat Journal |
| source_id | 49 |
| spelling | Qiu, Yue Li, Xiaodan Zhang, Xin Wang, Wei Chen, Jun Liu, Yali Fang, Xiaolian Ni, Xin Zhang, Jie Wang, Shengcai Tai, Jun 0145-5613 1942-7522 SAGE Publications Otorhinolaryngology http://dx.doi.org/10.1177/0145561320965208 <jats:sec><jats:title>Background:</jats:title><jats:p> Previous studies revealed that the prothrombotic factors in patients with obstructive sleep apnea (OSA) remain controversial. </jats:p></jats:sec><jats:sec><jats:title>Aim/Objective:</jats:title><jats:p> The aim of the systematic review is to elucidate the relationship between prothrombotic factors and OSA. </jats:p></jats:sec><jats:sec><jats:title>Materials and Methods:</jats:title><jats:p> This systematic review was performed under the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The literature we investigated was extracted from 4 main medical databases (PubMed, Web of Science, Cochrane Library, and Chinese databases) as of February 2020. We used significant weighted mean differences (SMDs) with 95% CIs from random-effects model. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> A total of 15 studies comprising 2190 patients were available for the meta-analysis. The pooled results showed that the levels of fibrinogen (SMD = 0.95, 95% CI = 0.26 to 1.65, P = .000), vascular endothelial growth factor (SMD = 0.37, 95% CI = −0.90 to 1.63, P = .000), and plasminogen activator inhibitor 1 (SMD = 0.61, 95% CI = 0.29 to 0.92, P = .040) increased in patients with OSA. There were no statistical differences between groups in terms of d-dimer ( P = .108) and platelet counts ( P = .233). Subgroup analyses demonstrated that specimen types and age could account for the heterogeneity. </jats:p></jats:sec><jats:sec><jats:title>Conclusions and Significance:</jats:title><jats:p> This meta-analysis indicated the relationship between prothrombotic factors in OSA hypopnea. Obstructive sleep apnea–related effects may underline the importance of considering the dysfunction of the hemostatic system. The prothrombotic factors in OSA can influence making a choice of appropriate therapy. </jats:p></jats:sec> Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis Ear, Nose & Throat Journal |
| spellingShingle | Qiu, Yue, Li, Xiaodan, Zhang, Xin, Wang, Wei, Chen, Jun, Liu, Yali, Fang, Xiaolian, Ni, Xin, Zhang, Jie, Wang, Shengcai, Tai, Jun, Ear, Nose & Throat Journal, Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis, Otorhinolaryngology |
| title | Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis |
| title_full | Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis |
| title_fullStr | Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis |
| title_full_unstemmed | Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis |
| title_short | Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis |
| title_sort | prothrombotic factors in obstructive sleep apnea: a systematic review with meta-analysis |
| title_unstemmed | Prothrombotic Factors in Obstructive Sleep Apnea: A Systematic Review With Meta-Analysis |
| topic | Otorhinolaryngology |
| url | http://dx.doi.org/10.1177/0145561320965208 |