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Yield of Reticulocyte Counts and Blood Smears in Term Infants
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| Zeitschriftentitel: | Clinical Pediatrics |
|---|---|
| Personen und Körperschaften: | , |
| In: | Clinical Pediatrics, 33, 1994, 2, S. 71-76 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
SAGE Publications
|
| Schlagwörter: |
| author_facet |
Newman, Thomas B. Easterling, M. Janet Newman, Thomas B. Easterling, M. Janet |
|---|---|
| author |
Newman, Thomas B. Easterling, M. Janet |
| spellingShingle |
Newman, Thomas B. Easterling, M. Janet Clinical Pediatrics Yield of Reticulocyte Counts and Blood Smears in Term Infants Pediatrics, Perinatology and Child Health |
| author_sort |
newman, thomas b. |
| spelling |
Newman, Thomas B. Easterling, M. Janet 0009-9228 1938-2707 SAGE Publications Pediatrics, Perinatology and Child Health http://dx.doi.org/10.1177/000992289403300202 <jats:p>Reticulocyte counts and blood smears are commonly recommended to evaluate jaundice in newborns. To investigate the results and diagnostic yield of these tests, we reviewed a computerized database and medical records of term newborns who had reticulocyte counts (n = 799) or blood smears (n = 781) within the first week after birth at two hospitals. Nearly a threefold difference was noted in reticulocyte counts between the two hospitals (median 8.0% vs 2.8%; P < .0001), apparently due to differences in laboratory methods. Among the patients with "abnormal" reticulocyte counts or blood smears (n = 192), isoimmunization was diagnosed in 54, presumed hemolysis of unknown etiology in two, G6PD deficiency in one, and pyropoikilocytosis in one. We conclude that better standardization of reticulocyte counts is needed. When ordered as screening tests for hemolysis in jaundiced infants, reticulocyte counts and blood smears seldom lead to diagnoses of hemolysis other than isoimmunization.</jats:p> Yield of Reticulocyte Counts and Blood Smears in Term Infants Clinical Pediatrics |
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| title |
Yield of Reticulocyte Counts and Blood Smears in Term Infants |
| title_unstemmed |
Yield of Reticulocyte Counts and Blood Smears in Term Infants |
| title_full |
Yield of Reticulocyte Counts and Blood Smears in Term Infants |
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Yield of Reticulocyte Counts and Blood Smears in Term Infants |
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Yield of Reticulocyte Counts and Blood Smears in Term Infants |
| title_short |
Yield of Reticulocyte Counts and Blood Smears in Term Infants |
| title_sort |
yield of reticulocyte counts and blood smears in term infants |
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Pediatrics, Perinatology and Child Health |
| url |
http://dx.doi.org/10.1177/000992289403300202 |
| publishDate |
1994 |
| physical |
71-76 |
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<jats:p>Reticulocyte counts and blood smears are commonly recommended to evaluate jaundice in newborns. To investigate the results and diagnostic yield of these tests, we reviewed a computerized database and medical records of term newborns who had reticulocyte counts (n = 799) or blood smears (n = 781) within the first week after birth at two hospitals. Nearly a threefold difference was noted in reticulocyte counts between the two hospitals (median 8.0% vs 2.8%; P < .0001), apparently due to differences in laboratory methods. Among the patients with "abnormal" reticulocyte counts or blood smears (n = 192), isoimmunization was diagnosed in 54, presumed hemolysis of unknown etiology in two, G6PD deficiency in one, and pyropoikilocytosis in one. We conclude that better standardization of reticulocyte counts is needed. When ordered as screening tests for hemolysis in jaundiced infants, reticulocyte counts and blood smears seldom lead to diagnoses of hemolysis other than isoimmunization.</jats:p> |
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| author | Newman, Thomas B., Easterling, M. Janet |
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| author_sort | newman, thomas b. |
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| description | <jats:p>Reticulocyte counts and blood smears are commonly recommended to evaluate jaundice in newborns. To investigate the results and diagnostic yield of these tests, we reviewed a computerized database and medical records of term newborns who had reticulocyte counts (n = 799) or blood smears (n = 781) within the first week after birth at two hospitals. Nearly a threefold difference was noted in reticulocyte counts between the two hospitals (median 8.0% vs 2.8%; P < .0001), apparently due to differences in laboratory methods. Among the patients with "abnormal" reticulocyte counts or blood smears (n = 192), isoimmunization was diagnosed in 54, presumed hemolysis of unknown etiology in two, G6PD deficiency in one, and pyropoikilocytosis in one. We conclude that better standardization of reticulocyte counts is needed. When ordered as screening tests for hemolysis in jaundiced infants, reticulocyte counts and blood smears seldom lead to diagnoses of hemolysis other than isoimmunization.</jats:p> |
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| imprint | SAGE Publications, 1994 |
| imprint_str_mv | SAGE Publications, 1994 |
| institution | DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Gla1, DE-Zi4 |
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| series | Clinical Pediatrics |
| source_id | 49 |
| spelling | Newman, Thomas B. Easterling, M. Janet 0009-9228 1938-2707 SAGE Publications Pediatrics, Perinatology and Child Health http://dx.doi.org/10.1177/000992289403300202 <jats:p>Reticulocyte counts and blood smears are commonly recommended to evaluate jaundice in newborns. To investigate the results and diagnostic yield of these tests, we reviewed a computerized database and medical records of term newborns who had reticulocyte counts (n = 799) or blood smears (n = 781) within the first week after birth at two hospitals. Nearly a threefold difference was noted in reticulocyte counts between the two hospitals (median 8.0% vs 2.8%; P < .0001), apparently due to differences in laboratory methods. Among the patients with "abnormal" reticulocyte counts or blood smears (n = 192), isoimmunization was diagnosed in 54, presumed hemolysis of unknown etiology in two, G6PD deficiency in one, and pyropoikilocytosis in one. We conclude that better standardization of reticulocyte counts is needed. When ordered as screening tests for hemolysis in jaundiced infants, reticulocyte counts and blood smears seldom lead to diagnoses of hemolysis other than isoimmunization.</jats:p> Yield of Reticulocyte Counts and Blood Smears in Term Infants Clinical Pediatrics |
| spellingShingle | Newman, Thomas B., Easterling, M. Janet, Clinical Pediatrics, Yield of Reticulocyte Counts and Blood Smears in Term Infants, Pediatrics, Perinatology and Child Health |
| title | Yield of Reticulocyte Counts and Blood Smears in Term Infants |
| title_full | Yield of Reticulocyte Counts and Blood Smears in Term Infants |
| title_fullStr | Yield of Reticulocyte Counts and Blood Smears in Term Infants |
| title_full_unstemmed | Yield of Reticulocyte Counts and Blood Smears in Term Infants |
| title_short | Yield of Reticulocyte Counts and Blood Smears in Term Infants |
| title_sort | yield of reticulocyte counts and blood smears in term infants |
| title_unstemmed | Yield of Reticulocyte Counts and Blood Smears in Term Infants |
| topic | Pediatrics, Perinatology and Child Health |
| url | http://dx.doi.org/10.1177/000992289403300202 |