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Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging
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| Zeitschriftentitel: | Journal of Biomedicine and Biotechnology |
|---|---|
| Personen und Körperschaften: | , , , , , , |
| In: | Journal of Biomedicine and Biotechnology, 2012, 2012, S. 1-14 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Hindawi Limited
|
| Schlagwörter: |
| author_facet |
Greco, A. Mancini, M. Gargiulo, S. Gramanzini, M. Claudio, P. P. Brunetti, A. Salvatore, M. Greco, A. Mancini, M. Gargiulo, S. Gramanzini, M. Claudio, P. P. Brunetti, A. Salvatore, M. |
|---|---|
| author |
Greco, A. Mancini, M. Gargiulo, S. Gramanzini, M. Claudio, P. P. Brunetti, A. Salvatore, M. |
| spellingShingle |
Greco, A. Mancini, M. Gargiulo, S. Gramanzini, M. Claudio, P. P. Brunetti, A. Salvatore, M. Journal of Biomedicine and Biotechnology Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging Health, Toxicology and Mutagenesis Genetics Molecular Biology Molecular Medicine General Medicine Biotechnology |
| author_sort |
greco, a. |
| spelling |
Greco, A. Mancini, M. Gargiulo, S. Gramanzini, M. Claudio, P. P. Brunetti, A. Salvatore, M. 1110-7243 1110-7251 Hindawi Limited Health, Toxicology and Mutagenesis Genetics Molecular Biology Molecular Medicine General Medicine Biotechnology http://dx.doi.org/10.1155/2012/519238 <jats:p>Ultrasound biomicroscopy (UBM) is a noninvasive multimodality technique that allows high-resolution imaging in mice. It is affordable, widely available, and portable. When it is coupled to Doppler ultrasound with color and power Doppler, it can be used to quantify blood flow and to image microcirculation as well as the response of tumor blood supply to cancer therapy. Target contrast ultrasound combines ultrasound with novel molecular targeted contrast agent to assess biological processes at molecular level. UBM is useful to investigate the growth and differentiation of tumors as well as to detect early molecular expression of cancer-related biomarkers<jats:italic>in vivo</jats:italic>and to monitor the effects of cancer therapies. It can be also used to visualize the embryological development of mice in uterus or to examine their cardiovascular development. The availability of real-time imaging of mice anatomy allows performing aspiration procedures under ultrasound guidance as well as the microinjection of cells, viruses, or other agents into precise locations. This paper will describe some basic principles of high-resolution imaging equipment, and the most important applications in molecular and preclinical imaging in small animal research.</jats:p> Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging Journal of Biomedicine and Biotechnology |
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| title |
Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging |
| title_unstemmed |
Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging |
| title_full |
Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging |
| title_fullStr |
Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging |
| title_full_unstemmed |
Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging |
| title_short |
Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging |
| title_sort |
ultrasound biomicroscopy in small animal research: applications in molecular and preclinical imaging |
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Health, Toxicology and Mutagenesis Genetics Molecular Biology Molecular Medicine General Medicine Biotechnology |
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http://dx.doi.org/10.1155/2012/519238 |
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2012 |
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1-14 |
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<jats:p>Ultrasound biomicroscopy (UBM) is a noninvasive multimodality technique that allows high-resolution imaging in mice. It is affordable, widely available, and portable. When it is coupled to Doppler ultrasound with color and power Doppler, it can be used to quantify blood flow and to image microcirculation as well as the response of tumor blood supply to cancer therapy. Target contrast ultrasound combines ultrasound with novel molecular targeted contrast agent to assess biological processes at molecular level. UBM is useful to investigate the growth and differentiation of tumors as well as to detect early molecular expression of cancer-related biomarkers<jats:italic>in vivo</jats:italic>and to monitor the effects of cancer therapies. It can be also used to visualize the embryological development of mice in uterus or to examine their cardiovascular development. The availability of real-time imaging of mice anatomy allows performing aspiration procedures under ultrasound guidance as well as the microinjection of cells, viruses, or other agents into precise locations. This paper will describe some basic principles of high-resolution imaging equipment, and the most important applications in molecular and preclinical imaging in small animal research.</jats:p> |
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| author | Greco, A., Mancini, M., Gargiulo, S., Gramanzini, M., Claudio, P. P., Brunetti, A., Salvatore, M. |
| author_facet | Greco, A., Mancini, M., Gargiulo, S., Gramanzini, M., Claudio, P. P., Brunetti, A., Salvatore, M., Greco, A., Mancini, M., Gargiulo, S., Gramanzini, M., Claudio, P. P., Brunetti, A., Salvatore, M. |
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| description | <jats:p>Ultrasound biomicroscopy (UBM) is a noninvasive multimodality technique that allows high-resolution imaging in mice. It is affordable, widely available, and portable. When it is coupled to Doppler ultrasound with color and power Doppler, it can be used to quantify blood flow and to image microcirculation as well as the response of tumor blood supply to cancer therapy. Target contrast ultrasound combines ultrasound with novel molecular targeted contrast agent to assess biological processes at molecular level. UBM is useful to investigate the growth and differentiation of tumors as well as to detect early molecular expression of cancer-related biomarkers<jats:italic>in vivo</jats:italic>and to monitor the effects of cancer therapies. It can be also used to visualize the embryological development of mice in uterus or to examine their cardiovascular development. The availability of real-time imaging of mice anatomy allows performing aspiration procedures under ultrasound guidance as well as the microinjection of cells, viruses, or other agents into precise locations. This paper will describe some basic principles of high-resolution imaging equipment, and the most important applications in molecular and preclinical imaging in small animal research.</jats:p> |
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| spelling | Greco, A. Mancini, M. Gargiulo, S. Gramanzini, M. Claudio, P. P. Brunetti, A. Salvatore, M. 1110-7243 1110-7251 Hindawi Limited Health, Toxicology and Mutagenesis Genetics Molecular Biology Molecular Medicine General Medicine Biotechnology http://dx.doi.org/10.1155/2012/519238 <jats:p>Ultrasound biomicroscopy (UBM) is a noninvasive multimodality technique that allows high-resolution imaging in mice. It is affordable, widely available, and portable. When it is coupled to Doppler ultrasound with color and power Doppler, it can be used to quantify blood flow and to image microcirculation as well as the response of tumor blood supply to cancer therapy. Target contrast ultrasound combines ultrasound with novel molecular targeted contrast agent to assess biological processes at molecular level. UBM is useful to investigate the growth and differentiation of tumors as well as to detect early molecular expression of cancer-related biomarkers<jats:italic>in vivo</jats:italic>and to monitor the effects of cancer therapies. It can be also used to visualize the embryological development of mice in uterus or to examine their cardiovascular development. The availability of real-time imaging of mice anatomy allows performing aspiration procedures under ultrasound guidance as well as the microinjection of cells, viruses, or other agents into precise locations. This paper will describe some basic principles of high-resolution imaging equipment, and the most important applications in molecular and preclinical imaging in small animal research.</jats:p> Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging Journal of Biomedicine and Biotechnology |
| spellingShingle | Greco, A., Mancini, M., Gargiulo, S., Gramanzini, M., Claudio, P. P., Brunetti, A., Salvatore, M., Journal of Biomedicine and Biotechnology, Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging, Health, Toxicology and Mutagenesis, Genetics, Molecular Biology, Molecular Medicine, General Medicine, Biotechnology |
| title | Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging |
| title_full | Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging |
| title_fullStr | Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging |
| title_full_unstemmed | Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging |
| title_short | Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging |
| title_sort | ultrasound biomicroscopy in small animal research: applications in molecular and preclinical imaging |
| title_unstemmed | Ultrasound Biomicroscopy in Small Animal Research: Applications in Molecular and Preclinical Imaging |
| topic | Health, Toxicology and Mutagenesis, Genetics, Molecular Biology, Molecular Medicine, General Medicine, Biotechnology |
| url | http://dx.doi.org/10.1155/2012/519238 |