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The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis
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| Zeitschriftentitel: | Journal of Biomedicine and Biotechnology |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Journal of Biomedicine and Biotechnology, 2012, 2012, S. 1-16 |
| Format: | E-Article |
| Sprache: | Englisch |
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Hindawi Limited
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Antunes, Ricardo F. Kaski, Juan Carlos Dumitriu, Ingrid E. Antunes, Ricardo F. Kaski, Juan Carlos Dumitriu, Ingrid E. |
|---|---|
| author |
Antunes, Ricardo F. Kaski, Juan Carlos Dumitriu, Ingrid E. |
| spellingShingle |
Antunes, Ricardo F. Kaski, Juan Carlos Dumitriu, Ingrid E. Journal of Biomedicine and Biotechnology The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis Health, Toxicology and Mutagenesis Genetics Molecular Biology Molecular Medicine General Medicine Biotechnology |
| author_sort |
antunes, ricardo f. |
| spelling |
Antunes, Ricardo F. Kaski, Juan Carlos Dumitriu, Ingrid E. 1110-7243 1110-7251 Hindawi Limited Health, Toxicology and Mutagenesis Genetics Molecular Biology Molecular Medicine General Medicine Biotechnology http://dx.doi.org/10.1155/2012/464532 <jats:p>Atherosclerosis is a chronic inflammatory disease that is mediated by both the innate and adaptive immune responses. T lymphocytes, that together with B cells are the cellular effectors of the adaptive immune system, are currently endowed with crucial roles in the development and progression of atherosclerosis. Costimulatory receptors are a class of molecules expressed by T lymphocytes that regulate the activation of T cells and the generation of effector T-cell responses. In this review we present the roles of costimulatory receptors of the tumour necrosis factor receptor (TNFR) superfamily in atherosclerosis and discuss the implications for future therapies that could be used to specifically modulate the immune response of pathogenic T cells in this disease.</jats:p> The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis Journal of Biomedicine and Biotechnology |
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| title |
The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis |
| title_unstemmed |
The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis |
| title_full |
The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis |
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The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis |
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The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis |
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The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis |
| title_sort |
the role of costimulatory receptors of the tumour necrosis factor receptor family in atherosclerosis |
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Health, Toxicology and Mutagenesis Genetics Molecular Biology Molecular Medicine General Medicine Biotechnology |
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http://dx.doi.org/10.1155/2012/464532 |
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2012 |
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1-16 |
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<jats:p>Atherosclerosis is a chronic inflammatory disease that is mediated by both the innate and adaptive immune responses. T lymphocytes, that together with B cells are the cellular effectors of the adaptive immune system, are currently endowed with crucial roles in the development and progression of atherosclerosis. Costimulatory receptors are a class of molecules expressed by T lymphocytes that regulate the activation of T cells and the generation of effector T-cell responses. In this review we present the roles of costimulatory receptors of the tumour necrosis factor receptor (TNFR) superfamily in atherosclerosis and discuss the implications for future therapies that could be used to specifically modulate the immune response of pathogenic T cells in this disease.</jats:p> |
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| description | <jats:p>Atherosclerosis is a chronic inflammatory disease that is mediated by both the innate and adaptive immune responses. T lymphocytes, that together with B cells are the cellular effectors of the adaptive immune system, are currently endowed with crucial roles in the development and progression of atherosclerosis. Costimulatory receptors are a class of molecules expressed by T lymphocytes that regulate the activation of T cells and the generation of effector T-cell responses. In this review we present the roles of costimulatory receptors of the tumour necrosis factor receptor (TNFR) superfamily in atherosclerosis and discuss the implications for future therapies that could be used to specifically modulate the immune response of pathogenic T cells in this disease.</jats:p> |
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| spelling | Antunes, Ricardo F. Kaski, Juan Carlos Dumitriu, Ingrid E. 1110-7243 1110-7251 Hindawi Limited Health, Toxicology and Mutagenesis Genetics Molecular Biology Molecular Medicine General Medicine Biotechnology http://dx.doi.org/10.1155/2012/464532 <jats:p>Atherosclerosis is a chronic inflammatory disease that is mediated by both the innate and adaptive immune responses. T lymphocytes, that together with B cells are the cellular effectors of the adaptive immune system, are currently endowed with crucial roles in the development and progression of atherosclerosis. Costimulatory receptors are a class of molecules expressed by T lymphocytes that regulate the activation of T cells and the generation of effector T-cell responses. In this review we present the roles of costimulatory receptors of the tumour necrosis factor receptor (TNFR) superfamily in atherosclerosis and discuss the implications for future therapies that could be used to specifically modulate the immune response of pathogenic T cells in this disease.</jats:p> The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis Journal of Biomedicine and Biotechnology |
| spellingShingle | Antunes, Ricardo F., Kaski, Juan Carlos, Dumitriu, Ingrid E., Journal of Biomedicine and Biotechnology, The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis, Health, Toxicology and Mutagenesis, Genetics, Molecular Biology, Molecular Medicine, General Medicine, Biotechnology |
| title | The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis |
| title_full | The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis |
| title_fullStr | The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis |
| title_full_unstemmed | The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis |
| title_short | The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis |
| title_sort | the role of costimulatory receptors of the tumour necrosis factor receptor family in atherosclerosis |
| title_unstemmed | The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis |
| topic | Health, Toxicology and Mutagenesis, Genetics, Molecular Biology, Molecular Medicine, General Medicine, Biotechnology |
| url | http://dx.doi.org/10.1155/2012/464532 |