Eintrag weiter verarbeiten
Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry
Gespeichert in:
| Zeitschriftentitel: | Journal of Oncology |
|---|---|
| Personen und Körperschaften: | , , , , |
| In: | Journal of Oncology, 2012, 2012, S. 1-6 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Hindawi Limited
|
| Schlagwörter: |
| author_facet |
Kotoyan, Raffi Metzger, Tiffany Tatum, Cliff Robbins, Ken Martin, Robert C. G. Kotoyan, Raffi Metzger, Tiffany Tatum, Cliff Robbins, Ken Martin, Robert C. G. |
|---|---|
| author |
Kotoyan, Raffi Metzger, Tiffany Tatum, Cliff Robbins, Ken Martin, Robert C. G. |
| spellingShingle |
Kotoyan, Raffi Metzger, Tiffany Tatum, Cliff Robbins, Ken Martin, Robert C. G. Journal of Oncology Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry Oncology |
| author_sort |
kotoyan, raffi |
| spelling |
Kotoyan, Raffi Metzger, Tiffany Tatum, Cliff Robbins, Ken Martin, Robert C. G. 1687-8450 1687-8469 Hindawi Limited Oncology http://dx.doi.org/10.1155/2012/168303 <jats:p><jats:italic>Introduction</jats:italic>. There has been limited reporting on the use of hepatic-directed therapy in liver dominant hepatic metastases arising from pancreatic cancer.<jats:italic>Methods</jats:italic>. An IRB-approved prospective multi-institutional treatment registry of 885 patients undergoing 1458 treatments for primary or secondary cancers in the liver was evaluated from January 2007 to January 2011.<jats:italic>Results</jats:italic>. Ten patients underwent a total of 17 treatment sessions with drug-eluting beads (DEBs). Six patients received concurrent chemotherapy while undergoing DEB with no severe adverse events. After a median followup of 16 months, the 6- and 12-month response rates were 80% and 75%, respectively, with a median overall survival of 9.3 months.<jats:italic>Conclusion</jats:italic>. Hepatic arterial therapy with DEB can be safely and effectively used in selected patients with liver predominant metastatic disease from pancreatic cancer. This therapy should be considered in combination with systemic chemotherapy as a possible second therapy given the limited response rates of second-line chemotherapy.</jats:p> Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry Journal of Oncology |
| doi_str_mv |
10.1155/2012/168303 |
| facet_avail |
Online Free |
| finc_class_facet |
Medizin |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE1NS8yMDEyLzE2ODMwMw |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE1NS8yMDEyLzE2ODMwMw |
| institution |
DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 |
| imprint |
Hindawi Limited, 2012 |
| imprint_str_mv |
Hindawi Limited, 2012 |
| issn |
1687-8450 1687-8469 |
| issn_str_mv |
1687-8450 1687-8469 |
| language |
English |
| mega_collection |
Hindawi Limited (CrossRef) |
| match_str |
kotoyan2012hepaticarterialtherapywithdrugelutingbeadsinthemanagementofmetastaticpancreaticcarcinomatotheliveramultiinstitutionalregistry |
| publishDateSort |
2012 |
| publisher |
Hindawi Limited |
| recordtype |
ai |
| record_format |
ai |
| series |
Journal of Oncology |
| source_id |
49 |
| title |
Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry |
| title_unstemmed |
Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry |
| title_full |
Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry |
| title_fullStr |
Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry |
| title_full_unstemmed |
Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry |
| title_short |
Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry |
| title_sort |
hepatic arterial therapy with drug-eluting beads in the management of metastatic pancreatic carcinoma to the liver: a multi-institutional registry |
| topic |
Oncology |
| url |
http://dx.doi.org/10.1155/2012/168303 |
| publishDate |
2012 |
| physical |
1-6 |
| description |
<jats:p><jats:italic>Introduction</jats:italic>. There has been limited reporting on the use of hepatic-directed therapy in liver dominant hepatic metastases arising from pancreatic cancer.<jats:italic>Methods</jats:italic>. An IRB-approved prospective multi-institutional treatment registry of 885 patients undergoing 1458 treatments for primary or secondary cancers in the liver was evaluated from January 2007 to January 2011.<jats:italic>Results</jats:italic>. Ten patients underwent a total of 17 treatment sessions with drug-eluting beads (DEBs). Six patients received concurrent chemotherapy while undergoing DEB with no severe adverse events. After a median followup of 16 months, the 6- and 12-month response rates were 80% and 75%, respectively, with a median overall survival of 9.3 months.<jats:italic>Conclusion</jats:italic>. Hepatic arterial therapy with DEB can be safely and effectively used in selected patients with liver predominant metastatic disease from pancreatic cancer. This therapy should be considered in combination with systemic chemotherapy as a possible second therapy given the limited response rates of second-line chemotherapy.</jats:p> |
| container_start_page |
1 |
| container_title |
Journal of Oncology |
| container_volume |
2012 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792334165749792773 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T14:24:19.356Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Hepatic+Arterial+Therapy+with+Drug-Eluting+Beads+in+the+Management+of+Metastatic+Pancreatic+Carcinoma+to+the+Liver%3A+A+Multi-Institutional+Registry&rft.date=2012-01-01&genre=article&issn=1687-8469&volume=2012&spage=1&epage=6&pages=1-6&jtitle=Journal+of+Oncology&atitle=Hepatic+Arterial+Therapy+with+Drug-Eluting+Beads+in+the+Management+of+Metastatic+Pancreatic+Carcinoma+to+the+Liver%3A+A+Multi-Institutional+Registry&aulast=Martin&aufirst=Robert+C.+G.&rft_id=info%3Adoi%2F10.1155%2F2012%2F168303&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792334165749792773 |
| author | Kotoyan, Raffi, Metzger, Tiffany, Tatum, Cliff, Robbins, Ken, Martin, Robert C. G. |
| author_facet | Kotoyan, Raffi, Metzger, Tiffany, Tatum, Cliff, Robbins, Ken, Martin, Robert C. G., Kotoyan, Raffi, Metzger, Tiffany, Tatum, Cliff, Robbins, Ken, Martin, Robert C. G. |
| author_sort | kotoyan, raffi |
| container_start_page | 1 |
| container_title | Journal of Oncology |
| container_volume | 2012 |
| description | <jats:p><jats:italic>Introduction</jats:italic>. There has been limited reporting on the use of hepatic-directed therapy in liver dominant hepatic metastases arising from pancreatic cancer.<jats:italic>Methods</jats:italic>. An IRB-approved prospective multi-institutional treatment registry of 885 patients undergoing 1458 treatments for primary or secondary cancers in the liver was evaluated from January 2007 to January 2011.<jats:italic>Results</jats:italic>. Ten patients underwent a total of 17 treatment sessions with drug-eluting beads (DEBs). Six patients received concurrent chemotherapy while undergoing DEB with no severe adverse events. After a median followup of 16 months, the 6- and 12-month response rates were 80% and 75%, respectively, with a median overall survival of 9.3 months.<jats:italic>Conclusion</jats:italic>. Hepatic arterial therapy with DEB can be safely and effectively used in selected patients with liver predominant metastatic disease from pancreatic cancer. This therapy should be considered in combination with systemic chemotherapy as a possible second therapy given the limited response rates of second-line chemotherapy.</jats:p> |
| doi_str_mv | 10.1155/2012/168303 |
| facet_avail | Online, Free |
| finc_class_facet | Medizin |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE1NS8yMDEyLzE2ODMwMw |
| imprint | Hindawi Limited, 2012 |
| imprint_str_mv | Hindawi Limited, 2012 |
| institution | DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14 |
| issn | 1687-8450, 1687-8469 |
| issn_str_mv | 1687-8450, 1687-8469 |
| language | English |
| last_indexed | 2024-03-01T14:24:19.356Z |
| match_str | kotoyan2012hepaticarterialtherapywithdrugelutingbeadsinthemanagementofmetastaticpancreaticcarcinomatotheliveramultiinstitutionalregistry |
| mega_collection | Hindawi Limited (CrossRef) |
| physical | 1-6 |
| publishDate | 2012 |
| publishDateSort | 2012 |
| publisher | Hindawi Limited |
| record_format | ai |
| recordtype | ai |
| series | Journal of Oncology |
| source_id | 49 |
| spelling | Kotoyan, Raffi Metzger, Tiffany Tatum, Cliff Robbins, Ken Martin, Robert C. G. 1687-8450 1687-8469 Hindawi Limited Oncology http://dx.doi.org/10.1155/2012/168303 <jats:p><jats:italic>Introduction</jats:italic>. There has been limited reporting on the use of hepatic-directed therapy in liver dominant hepatic metastases arising from pancreatic cancer.<jats:italic>Methods</jats:italic>. An IRB-approved prospective multi-institutional treatment registry of 885 patients undergoing 1458 treatments for primary or secondary cancers in the liver was evaluated from January 2007 to January 2011.<jats:italic>Results</jats:italic>. Ten patients underwent a total of 17 treatment sessions with drug-eluting beads (DEBs). Six patients received concurrent chemotherapy while undergoing DEB with no severe adverse events. After a median followup of 16 months, the 6- and 12-month response rates were 80% and 75%, respectively, with a median overall survival of 9.3 months.<jats:italic>Conclusion</jats:italic>. Hepatic arterial therapy with DEB can be safely and effectively used in selected patients with liver predominant metastatic disease from pancreatic cancer. This therapy should be considered in combination with systemic chemotherapy as a possible second therapy given the limited response rates of second-line chemotherapy.</jats:p> Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry Journal of Oncology |
| spellingShingle | Kotoyan, Raffi, Metzger, Tiffany, Tatum, Cliff, Robbins, Ken, Martin, Robert C. G., Journal of Oncology, Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry, Oncology |
| title | Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry |
| title_full | Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry |
| title_fullStr | Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry |
| title_full_unstemmed | Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry |
| title_short | Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry |
| title_sort | hepatic arterial therapy with drug-eluting beads in the management of metastatic pancreatic carcinoma to the liver: a multi-institutional registry |
| title_unstemmed | Hepatic Arterial Therapy with Drug-Eluting Beads in the Management of Metastatic Pancreatic Carcinoma to the Liver: A Multi-Institutional Registry |
| topic | Oncology |
| url | http://dx.doi.org/10.1155/2012/168303 |