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Surveillance as an Option for the Treatment of Small Renal Masses
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| Zeitschriftentitel: | Advances in Urology |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Advances in Urology, 2008, 2008, S. 1-6 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Hindawi Limited
|
| Schlagwörter: |
| author_facet |
Klaver, S. Joniau, S. Van Poppel, H. Klaver, S. Joniau, S. Van Poppel, H. |
|---|---|
| author |
Klaver, S. Joniau, S. Van Poppel, H. |
| spellingShingle |
Klaver, S. Joniau, S. Van Poppel, H. Advances in Urology Surveillance as an Option for the Treatment of Small Renal Masses Urology Obstetrics and Gynecology |
| author_sort |
klaver, s. |
| spelling |
Klaver, S. Joniau, S. Van Poppel, H. 1687-6369 1687-6377 Hindawi Limited Urology Obstetrics and Gynecology http://dx.doi.org/10.1155/2008/705958 <jats:p><jats:italic>Objectives</jats:italic>. To review the natural history and biological potential of small renal masses in order to evaluate surveillance as a treatment option.<jats:italic>Methods</jats:italic>. Literature search of Medline and additional references from non-Medline-indexed publications concerning surveillance of small renal masses.<jats:italic>Results</jats:italic>. The natural history and biological potential of small renal masses can still not be unambiguously predicted at present. There seems to be no clear correlation between tumour size and presence of benign histology. The majority of small renal masses grow and the majority are cancer, but one cannot safely assume that a lack of growth on serial CT scans is the confirmation of absence of malignancy. Needle core biopsies could be used to help in decision making. They show a high accuracy for histopathological tumour type but are less accurate in evaluating Fuhrman grade.<jats:italic>Conclusions</jats:italic>. At present, surveillance of small renal masses should only be considered in elderly and/or infirm patients with competing health risks, in those with a limited life expectancy, and in those for whom minimal invasive treatment or surgery is not an option. In all other patients, active surveillance should only be considered in the context of a study protocol. Long-term, prospective studies are needed to provide a more accurate assessment of the natural history and metastastic potential of small renal masses.</jats:p> Surveillance as an Option for the Treatment of Small Renal Masses Advances in Urology |
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| title |
Surveillance as an Option for the Treatment of Small Renal Masses |
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Surveillance as an Option for the Treatment of Small Renal Masses |
| title_full |
Surveillance as an Option for the Treatment of Small Renal Masses |
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Surveillance as an Option for the Treatment of Small Renal Masses |
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Surveillance as an Option for the Treatment of Small Renal Masses |
| title_short |
Surveillance as an Option for the Treatment of Small Renal Masses |
| title_sort |
surveillance as an option for the treatment of small renal masses |
| topic |
Urology Obstetrics and Gynecology |
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http://dx.doi.org/10.1155/2008/705958 |
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2008 |
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1-6 |
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<jats:p><jats:italic>Objectives</jats:italic>. To review the natural history and biological potential of small renal masses in order to evaluate surveillance as a treatment option.<jats:italic>Methods</jats:italic>. Literature search of Medline and additional references from non-Medline-indexed publications concerning surveillance of small renal masses.<jats:italic>Results</jats:italic>. The natural history and biological potential of small renal masses can still not be unambiguously predicted at present. There seems to be no clear correlation between tumour size and presence of benign histology. The majority of small renal masses grow and the majority are cancer, but one cannot safely assume that a lack of growth on serial CT scans is the confirmation of absence of malignancy. Needle core biopsies could be used to help in decision making. They show a high accuracy for histopathological tumour type but are less accurate in evaluating Fuhrman grade.<jats:italic>Conclusions</jats:italic>. At present, surveillance of small renal masses should only be considered in elderly and/or infirm patients with competing health risks, in those with a limited life expectancy, and in those for whom minimal invasive treatment or surgery is not an option. In all other patients, active surveillance should only be considered in the context of a study protocol. Long-term, prospective studies are needed to provide a more accurate assessment of the natural history and metastastic potential of small renal masses.</jats:p> |
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| description | <jats:p><jats:italic>Objectives</jats:italic>. To review the natural history and biological potential of small renal masses in order to evaluate surveillance as a treatment option.<jats:italic>Methods</jats:italic>. Literature search of Medline and additional references from non-Medline-indexed publications concerning surveillance of small renal masses.<jats:italic>Results</jats:italic>. The natural history and biological potential of small renal masses can still not be unambiguously predicted at present. There seems to be no clear correlation between tumour size and presence of benign histology. The majority of small renal masses grow and the majority are cancer, but one cannot safely assume that a lack of growth on serial CT scans is the confirmation of absence of malignancy. Needle core biopsies could be used to help in decision making. They show a high accuracy for histopathological tumour type but are less accurate in evaluating Fuhrman grade.<jats:italic>Conclusions</jats:italic>. At present, surveillance of small renal masses should only be considered in elderly and/or infirm patients with competing health risks, in those with a limited life expectancy, and in those for whom minimal invasive treatment or surgery is not an option. In all other patients, active surveillance should only be considered in the context of a study protocol. Long-term, prospective studies are needed to provide a more accurate assessment of the natural history and metastastic potential of small renal masses.</jats:p> |
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| spelling | Klaver, S. Joniau, S. Van Poppel, H. 1687-6369 1687-6377 Hindawi Limited Urology Obstetrics and Gynecology http://dx.doi.org/10.1155/2008/705958 <jats:p><jats:italic>Objectives</jats:italic>. To review the natural history and biological potential of small renal masses in order to evaluate surveillance as a treatment option.<jats:italic>Methods</jats:italic>. Literature search of Medline and additional references from non-Medline-indexed publications concerning surveillance of small renal masses.<jats:italic>Results</jats:italic>. The natural history and biological potential of small renal masses can still not be unambiguously predicted at present. There seems to be no clear correlation between tumour size and presence of benign histology. The majority of small renal masses grow and the majority are cancer, but one cannot safely assume that a lack of growth on serial CT scans is the confirmation of absence of malignancy. Needle core biopsies could be used to help in decision making. They show a high accuracy for histopathological tumour type but are less accurate in evaluating Fuhrman grade.<jats:italic>Conclusions</jats:italic>. At present, surveillance of small renal masses should only be considered in elderly and/or infirm patients with competing health risks, in those with a limited life expectancy, and in those for whom minimal invasive treatment or surgery is not an option. In all other patients, active surveillance should only be considered in the context of a study protocol. Long-term, prospective studies are needed to provide a more accurate assessment of the natural history and metastastic potential of small renal masses.</jats:p> Surveillance as an Option for the Treatment of Small Renal Masses Advances in Urology |
| spellingShingle | Klaver, S., Joniau, S., Van Poppel, H., Advances in Urology, Surveillance as an Option for the Treatment of Small Renal Masses, Urology, Obstetrics and Gynecology |
| title | Surveillance as an Option for the Treatment of Small Renal Masses |
| title_full | Surveillance as an Option for the Treatment of Small Renal Masses |
| title_fullStr | Surveillance as an Option for the Treatment of Small Renal Masses |
| title_full_unstemmed | Surveillance as an Option for the Treatment of Small Renal Masses |
| title_short | Surveillance as an Option for the Treatment of Small Renal Masses |
| title_sort | surveillance as an option for the treatment of small renal masses |
| title_unstemmed | Surveillance as an Option for the Treatment of Small Renal Masses |
| topic | Urology, Obstetrics and Gynecology |
| url | http://dx.doi.org/10.1155/2008/705958 |