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Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis
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| Zeitschriftentitel: | Canadian Journal of Infectious Diseases |
|---|---|
| Personen und Körperschaften: | , , , , , |
| In: | Canadian Journal of Infectious Diseases, 4, 1993, 6, S. 347-351 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Hindawi Limited
|
| Schlagwörter: |
| author_facet |
Bowie, William R Ast, Joanne Sibau, Linda Shaw, Carol Jones, Hugh D Black, William A Bowie, William R Ast, Joanne Sibau, Linda Shaw, Carol Jones, Hugh D Black, William A |
|---|---|
| author |
Bowie, William R Ast, Joanne Sibau, Linda Shaw, Carol Jones, Hugh D Black, William A |
| spellingShingle |
Bowie, William R Ast, Joanne Sibau, Linda Shaw, Carol Jones, Hugh D Black, William A Canadian Journal of Infectious Diseases Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis Microbiology (medical) |
| author_sort |
bowie, william r |
| spelling |
Bowie, William R Ast, Joanne Sibau, Linda Shaw, Carol Jones, Hugh D Black, William A 1180-2332 Hindawi Limited Microbiology (medical) http://dx.doi.org/10.1155/1993/613963 <jats:p>Men and women with gonorrhea or contact to gonorrhea are frequently co-infected with<jats:italic>Chlamydia trachomatis</jats:italic>. To assess the importance of using treatment regimens active against both<jats:italic>Neisseria gonorrhoeae</jats:italic>and<jats:italic>C trachomatis</jats:italic>, tetracycline 500 mg orally four times daily for five days, with activity against both organisms, was compared with ceftriaxone, 250 mg once intramuscularly, with activity against only<jats:italic>N gonorrhoeae. N gonorrhoeae</jats:italic>microbiological failure occurred in six of 148 patients (4%) on tetracycline and zero of 85 on ceftriaxone. Microbiological failure for<jats:italic>C trachomatis</jats:italic>occurred in zero of 27 on tetracycline and 10 of 12 (83%) on ceftriaxone (P<0.001). In addition, 14 others on ceftriaxone had<jats:italic>C trachomatis</jats:italic>first isolated after treatment. When all types of microbiologialc and clinical failures are included, outcome was significantly better on tetracycline (P<0.001). Optimal treatment of patients with gonorrhea must include regimens with activity against both<jats:italic>C trachomatis</jats:italic>and<jats:italic>N gonorrhoeae</jats:italic>.</jats:p> Need for Treatment of Gonorrhea to be Effective against<i>Chlamydia trachomatis</i> Canadian Journal of Infectious Diseases |
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| title |
Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis |
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Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis |
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Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis |
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Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis |
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Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis |
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Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis |
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need for treatment of gonorrhea to be effective against<i>chlamydia trachomatis</i> |
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Microbiology (medical) |
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http://dx.doi.org/10.1155/1993/613963 |
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1993 |
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347-351 |
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<jats:p>Men and women with gonorrhea or contact to gonorrhea are frequently co-infected with<jats:italic>Chlamydia trachomatis</jats:italic>. To assess the importance of using treatment regimens active against both<jats:italic>Neisseria gonorrhoeae</jats:italic>and<jats:italic>C trachomatis</jats:italic>, tetracycline 500 mg orally four times daily for five days, with activity against both organisms, was compared with ceftriaxone, 250 mg once intramuscularly, with activity against only<jats:italic>N gonorrhoeae. N gonorrhoeae</jats:italic>microbiological failure occurred in six of 148 patients (4%) on tetracycline and zero of 85 on ceftriaxone. Microbiological failure for<jats:italic>C trachomatis</jats:italic>occurred in zero of 27 on tetracycline and 10 of 12 (83%) on ceftriaxone (P<0.001). In addition, 14 others on ceftriaxone had<jats:italic>C trachomatis</jats:italic>first isolated after treatment. When all types of microbiologialc and clinical failures are included, outcome was significantly better on tetracycline (P<0.001). Optimal treatment of patients with gonorrhea must include regimens with activity against both<jats:italic>C trachomatis</jats:italic>and<jats:italic>N gonorrhoeae</jats:italic>.</jats:p> |
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| author | Bowie, William R, Ast, Joanne, Sibau, Linda, Shaw, Carol, Jones, Hugh D, Black, William A |
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| description | <jats:p>Men and women with gonorrhea or contact to gonorrhea are frequently co-infected with<jats:italic>Chlamydia trachomatis</jats:italic>. To assess the importance of using treatment regimens active against both<jats:italic>Neisseria gonorrhoeae</jats:italic>and<jats:italic>C trachomatis</jats:italic>, tetracycline 500 mg orally four times daily for five days, with activity against both organisms, was compared with ceftriaxone, 250 mg once intramuscularly, with activity against only<jats:italic>N gonorrhoeae. N gonorrhoeae</jats:italic>microbiological failure occurred in six of 148 patients (4%) on tetracycline and zero of 85 on ceftriaxone. Microbiological failure for<jats:italic>C trachomatis</jats:italic>occurred in zero of 27 on tetracycline and 10 of 12 (83%) on ceftriaxone (P<0.001). In addition, 14 others on ceftriaxone had<jats:italic>C trachomatis</jats:italic>first isolated after treatment. When all types of microbiologialc and clinical failures are included, outcome was significantly better on tetracycline (P<0.001). Optimal treatment of patients with gonorrhea must include regimens with activity against both<jats:italic>C trachomatis</jats:italic>and<jats:italic>N gonorrhoeae</jats:italic>.</jats:p> |
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| spelling | Bowie, William R Ast, Joanne Sibau, Linda Shaw, Carol Jones, Hugh D Black, William A 1180-2332 Hindawi Limited Microbiology (medical) http://dx.doi.org/10.1155/1993/613963 <jats:p>Men and women with gonorrhea or contact to gonorrhea are frequently co-infected with<jats:italic>Chlamydia trachomatis</jats:italic>. To assess the importance of using treatment regimens active against both<jats:italic>Neisseria gonorrhoeae</jats:italic>and<jats:italic>C trachomatis</jats:italic>, tetracycline 500 mg orally four times daily for five days, with activity against both organisms, was compared with ceftriaxone, 250 mg once intramuscularly, with activity against only<jats:italic>N gonorrhoeae. N gonorrhoeae</jats:italic>microbiological failure occurred in six of 148 patients (4%) on tetracycline and zero of 85 on ceftriaxone. Microbiological failure for<jats:italic>C trachomatis</jats:italic>occurred in zero of 27 on tetracycline and 10 of 12 (83%) on ceftriaxone (P<0.001). In addition, 14 others on ceftriaxone had<jats:italic>C trachomatis</jats:italic>first isolated after treatment. When all types of microbiologialc and clinical failures are included, outcome was significantly better on tetracycline (P<0.001). Optimal treatment of patients with gonorrhea must include regimens with activity against both<jats:italic>C trachomatis</jats:italic>and<jats:italic>N gonorrhoeae</jats:italic>.</jats:p> Need for Treatment of Gonorrhea to be Effective against<i>Chlamydia trachomatis</i> Canadian Journal of Infectious Diseases |
| spellingShingle | Bowie, William R, Ast, Joanne, Sibau, Linda, Shaw, Carol, Jones, Hugh D, Black, William A, Canadian Journal of Infectious Diseases, Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis, Microbiology (medical) |
| title | Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis |
| title_full | Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis |
| title_fullStr | Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis |
| title_full_unstemmed | Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis |
| title_short | Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis |
| title_sort | need for treatment of gonorrhea to be effective against<i>chlamydia trachomatis</i> |
| title_unstemmed | Need for Treatment of Gonorrhea to be Effective againstChlamydia trachomatis |
| topic | Microbiology (medical) |
| url | http://dx.doi.org/10.1155/1993/613963 |