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Patch Fluorometry: Shedding New Light on Ion Channels
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| Zeitschriftentitel: | Physiology |
|---|---|
| Personen und Körperschaften: | |
| In: | Physiology, 21, 2006, 1, S. 6-12 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Physiological Society
|
| Schlagwörter: |
| author_facet |
Zheng, Jie Zheng, Jie |
|---|---|
| author |
Zheng, Jie |
| spellingShingle |
Zheng, Jie Physiology Patch Fluorometry: Shedding New Light on Ion Channels Physiology |
| author_sort |
zheng, jie |
| spelling |
Zheng, Jie 1548-9213 1548-9221 American Physiological Society Physiology http://dx.doi.org/10.1152/physiol.00041.2005 <jats:p> Patch fluorometry has emerged as a new approach to the study of the structure-function relationship in membrane-embedded functional ion channels. Simultaneous fluorescent and electrical recordings are achieved from a small number of channels in a cell-free membrane patch, yielding high recording sensitivities. Further improvement of this approach should permit direct observation of the gating motion of a single-channel protein. </jats:p> Patch Fluorometry: Shedding New Light on Ion Channels Physiology |
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10.1152/physiol.00041.2005 |
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American Physiological Society, 2006 |
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American Physiological Society, 2006 |
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1548-9213 1548-9221 |
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2006 |
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American Physiological Society |
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Physiology |
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| title |
Patch Fluorometry: Shedding New Light on Ion Channels |
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Patch Fluorometry: Shedding New Light on Ion Channels |
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Patch Fluorometry: Shedding New Light on Ion Channels |
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Patch Fluorometry: Shedding New Light on Ion Channels |
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Patch Fluorometry: Shedding New Light on Ion Channels |
| title_short |
Patch Fluorometry: Shedding New Light on Ion Channels |
| title_sort |
patch fluorometry: shedding new light on ion channels |
| topic |
Physiology |
| url |
http://dx.doi.org/10.1152/physiol.00041.2005 |
| publishDate |
2006 |
| physical |
6-12 |
| description |
<jats:p> Patch fluorometry has emerged as a new approach to the study of the structure-function relationship in membrane-embedded functional ion channels. Simultaneous fluorescent and electrical recordings are achieved from a small number of channels in a cell-free membrane patch, yielding high recording sensitivities. Further improvement of this approach should permit direct observation of the gating motion of a single-channel protein. </jats:p> |
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| description | <jats:p> Patch fluorometry has emerged as a new approach to the study of the structure-function relationship in membrane-embedded functional ion channels. Simultaneous fluorescent and electrical recordings are achieved from a small number of channels in a cell-free membrane patch, yielding high recording sensitivities. Further improvement of this approach should permit direct observation of the gating motion of a single-channel protein. </jats:p> |
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| imprint | American Physiological Society, 2006 |
| imprint_str_mv | American Physiological Society, 2006 |
| institution | DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14 |
| issn | 1548-9213, 1548-9221 |
| issn_str_mv | 1548-9213, 1548-9221 |
| language | English |
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| spelling | Zheng, Jie 1548-9213 1548-9221 American Physiological Society Physiology http://dx.doi.org/10.1152/physiol.00041.2005 <jats:p> Patch fluorometry has emerged as a new approach to the study of the structure-function relationship in membrane-embedded functional ion channels. Simultaneous fluorescent and electrical recordings are achieved from a small number of channels in a cell-free membrane patch, yielding high recording sensitivities. Further improvement of this approach should permit direct observation of the gating motion of a single-channel protein. </jats:p> Patch Fluorometry: Shedding New Light on Ion Channels Physiology |
| spellingShingle | Zheng, Jie, Physiology, Patch Fluorometry: Shedding New Light on Ion Channels, Physiology |
| title | Patch Fluorometry: Shedding New Light on Ion Channels |
| title_full | Patch Fluorometry: Shedding New Light on Ion Channels |
| title_fullStr | Patch Fluorometry: Shedding New Light on Ion Channels |
| title_full_unstemmed | Patch Fluorometry: Shedding New Light on Ion Channels |
| title_short | Patch Fluorometry: Shedding New Light on Ion Channels |
| title_sort | patch fluorometry: shedding new light on ion channels |
| title_unstemmed | Patch Fluorometry: Shedding New Light on Ion Channels |
| topic | Physiology |
| url | http://dx.doi.org/10.1152/physiol.00041.2005 |