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Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics
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| Zeitschriftentitel: | Journal of Neurophysiology |
|---|---|
| Personen und Körperschaften: | , , , |
| In: | Journal of Neurophysiology, 113, 2015, 7, S. 2812-2823 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Physiological Society
|
| Schlagwörter: |
| author_facet |
Suminski, Aaron J. Mardoum, Philip Lillicrap, Timothy P. Hatsopoulos, Nicholas G. Suminski, Aaron J. Mardoum, Philip Lillicrap, Timothy P. Hatsopoulos, Nicholas G. |
|---|---|
| author |
Suminski, Aaron J. Mardoum, Philip Lillicrap, Timothy P. Hatsopoulos, Nicholas G. |
| spellingShingle |
Suminski, Aaron J. Mardoum, Philip Lillicrap, Timothy P. Hatsopoulos, Nicholas G. Journal of Neurophysiology Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics Physiology General Neuroscience |
| author_sort |
suminski, aaron j. |
| spelling |
Suminski, Aaron J. Mardoum, Philip Lillicrap, Timothy P. Hatsopoulos, Nicholas G. 0022-3077 1522-1598 American Physiological Society Physiology General Neuroscience http://dx.doi.org/10.1152/jn.00486.2014 <jats:p> A prevailing theory in the cortical control of limb movement posits that premotor cortex initiates a high-level motor plan that is transformed by the primary motor cortex (MI) into a low-level motor command to be executed. This theory implies that the premotor cortex is shielded from the motor periphery, and therefore, its activity should not represent the low-level features of movement. Contrary to this theory, we show that both dorsal (PMd) and ventral premotor (PMv) cortexes exhibit population-level tuning properties that reflect the biomechanical properties of the periphery similar to those observed in M1. We recorded single-unit activity from M1, PMd, and PMv and characterized their tuning properties while six rhesus macaques performed a reaching task in the horizontal plane. Each area exhibited a bimodal distribution of preferred directions during execution consistent with the known biomechanical anisotropies of the muscles and limb segments. Moreover, these distributions varied in orientation or shape from planning to execution. A network model shows that such population dynamics are linked to a change in biomechanics of the limb as the monkey begins to move, specifically to the state-dependent properties of muscles. We suggest that, like M1, neural populations in PMd and PMv are more directly linked with the motor periphery than previously thought. </jats:p> Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics Journal of Neurophysiology |
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| title |
Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| title_unstemmed |
Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| title_full |
Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| title_fullStr |
Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| title_full_unstemmed |
Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| title_short |
Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| title_sort |
temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| topic |
Physiology General Neuroscience |
| url |
http://dx.doi.org/10.1152/jn.00486.2014 |
| publishDate |
2015 |
| physical |
2812-2823 |
| description |
<jats:p> A prevailing theory in the cortical control of limb movement posits that premotor cortex initiates a high-level motor plan that is transformed by the primary motor cortex (MI) into a low-level motor command to be executed. This theory implies that the premotor cortex is shielded from the motor periphery, and therefore, its activity should not represent the low-level features of movement. Contrary to this theory, we show that both dorsal (PMd) and ventral premotor (PMv) cortexes exhibit population-level tuning properties that reflect the biomechanical properties of the periphery similar to those observed in M1. We recorded single-unit activity from M1, PMd, and PMv and characterized their tuning properties while six rhesus macaques performed a reaching task in the horizontal plane. Each area exhibited a bimodal distribution of preferred directions during execution consistent with the known biomechanical anisotropies of the muscles and limb segments. Moreover, these distributions varied in orientation or shape from planning to execution. A network model shows that such population dynamics are linked to a change in biomechanics of the limb as the monkey begins to move, specifically to the state-dependent properties of muscles. We suggest that, like M1, neural populations in PMd and PMv are more directly linked with the motor periphery than previously thought. </jats:p> |
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| author | Suminski, Aaron J., Mardoum, Philip, Lillicrap, Timothy P., Hatsopoulos, Nicholas G. |
| author_facet | Suminski, Aaron J., Mardoum, Philip, Lillicrap, Timothy P., Hatsopoulos, Nicholas G., Suminski, Aaron J., Mardoum, Philip, Lillicrap, Timothy P., Hatsopoulos, Nicholas G. |
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| description | <jats:p> A prevailing theory in the cortical control of limb movement posits that premotor cortex initiates a high-level motor plan that is transformed by the primary motor cortex (MI) into a low-level motor command to be executed. This theory implies that the premotor cortex is shielded from the motor periphery, and therefore, its activity should not represent the low-level features of movement. Contrary to this theory, we show that both dorsal (PMd) and ventral premotor (PMv) cortexes exhibit population-level tuning properties that reflect the biomechanical properties of the periphery similar to those observed in M1. We recorded single-unit activity from M1, PMd, and PMv and characterized their tuning properties while six rhesus macaques performed a reaching task in the horizontal plane. Each area exhibited a bimodal distribution of preferred directions during execution consistent with the known biomechanical anisotropies of the muscles and limb segments. Moreover, these distributions varied in orientation or shape from planning to execution. A network model shows that such population dynamics are linked to a change in biomechanics of the limb as the monkey begins to move, specifically to the state-dependent properties of muscles. We suggest that, like M1, neural populations in PMd and PMv are more directly linked with the motor periphery than previously thought. </jats:p> |
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| spelling | Suminski, Aaron J. Mardoum, Philip Lillicrap, Timothy P. Hatsopoulos, Nicholas G. 0022-3077 1522-1598 American Physiological Society Physiology General Neuroscience http://dx.doi.org/10.1152/jn.00486.2014 <jats:p> A prevailing theory in the cortical control of limb movement posits that premotor cortex initiates a high-level motor plan that is transformed by the primary motor cortex (MI) into a low-level motor command to be executed. This theory implies that the premotor cortex is shielded from the motor periphery, and therefore, its activity should not represent the low-level features of movement. Contrary to this theory, we show that both dorsal (PMd) and ventral premotor (PMv) cortexes exhibit population-level tuning properties that reflect the biomechanical properties of the periphery similar to those observed in M1. We recorded single-unit activity from M1, PMd, and PMv and characterized their tuning properties while six rhesus macaques performed a reaching task in the horizontal plane. Each area exhibited a bimodal distribution of preferred directions during execution consistent with the known biomechanical anisotropies of the muscles and limb segments. Moreover, these distributions varied in orientation or shape from planning to execution. A network model shows that such population dynamics are linked to a change in biomechanics of the limb as the monkey begins to move, specifically to the state-dependent properties of muscles. We suggest that, like M1, neural populations in PMd and PMv are more directly linked with the motor periphery than previously thought. </jats:p> Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics Journal of Neurophysiology |
| spellingShingle | Suminski, Aaron J., Mardoum, Philip, Lillicrap, Timothy P., Hatsopoulos, Nicholas G., Journal of Neurophysiology, Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics, Physiology, General Neuroscience |
| title | Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| title_full | Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| title_fullStr | Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| title_full_unstemmed | Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| title_short | Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| title_sort | temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| title_unstemmed | Temporal evolution of both premotor and motor cortical tuning properties reflect changes in limb biomechanics |
| topic | Physiology, General Neuroscience |
| url | http://dx.doi.org/10.1152/jn.00486.2014 |