Eintrag weiter verarbeiten
Topography of normal and high-amplitude esophageal peristalsis
Gespeichert in:
| Zeitschriftentitel: | American Journal of Physiology-Gastrointestinal and Liver Physiology |
|---|---|
| Personen und Körperschaften: | , |
| In: | American Journal of Physiology-Gastrointestinal and Liver Physiology, 265, 1993, 6, S. G1098-G1107 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
American Physiological Society
|
| Schlagwörter: |
| author_facet |
Clouse, R. E. Staiano, A. Clouse, R. E. Staiano, A. |
|---|---|
| author |
Clouse, R. E. Staiano, A. |
| spellingShingle |
Clouse, R. E. Staiano, A. American Journal of Physiology-Gastrointestinal and Liver Physiology Topography of normal and high-amplitude esophageal peristalsis Physiology (medical) Gastroenterology Hepatology Physiology |
| author_sort |
clouse, r. e. |
| spelling |
Clouse, R. E. Staiano, A. 0193-1857 1522-1547 American Physiological Society Physiology (medical) Gastroenterology Hepatology Physiology http://dx.doi.org/10.1152/ajpgi.1993.265.6.g1098 <jats:p> Topographic plots were created from esophageal manometric tracings in 12 asymptomatic volunteers and 10 symptomatic patients with high-amplitude peristaltic contraction waves (nutcracker esophagus) to identify segmental contraction differences between the two groups. Median waves at each centimeter of esophageal length were spatially interconnected using a computerized gridding and plotting system, and a characteristic peristaltic contraction from the proximal esophageal body through the lower sphincter was constructed for each subject. Contour plots in the volunteers revealed three amplitude troughs dividing the peristaltic contraction into four sequential segments: the skeletal muscle body, the proximal and distal segments of the smooth muscle body, and the lower sphincter region. In nutcracker-esophagus patients, only the first and third troughs could be identified, since augmented contraction in the distal smooth muscle segment blurred separation of the smooth muscle body segments. Volume measurements under the topographic plots showed no significant intergroup differences in contraction of the skeletal muscle region or lower sphincter but modest increase in contraction of the proximal smooth muscle segment [1.7 times normal, 95% confidence interval (CI) 1.2-2.0; P = 0.002 comparing 2 groups] and marked increase in the distal smooth muscle segment (2.7 times normal, 95% CI 2.0-3.3; P < 0.0001). These data indicate that normal peristalsis through the esophageal body and lower sphincter includes four separate contraction segments that can be distinguished with intraluminal manometry and the topographic analysis method. The nutcracker esophagus primarily affects the distal segment in the smooth muscle body. </jats:p> Topography of normal and high-amplitude esophageal peristalsis American Journal of Physiology-Gastrointestinal and Liver Physiology |
| doi_str_mv |
10.1152/ajpgi.1993.265.6.g1098 |
| facet_avail |
Online |
| finc_class_facet |
Biologie Medizin |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE1Mi9hanBnaS4xOTkzLjI2NS42LmcxMDk4 |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE1Mi9hanBnaS4xOTkzLjI2NS42LmcxMDk4 |
| institution |
DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-14 |
| imprint |
American Physiological Society, 1993 |
| imprint_str_mv |
American Physiological Society, 1993 |
| issn |
0193-1857 1522-1547 |
| issn_str_mv |
0193-1857 1522-1547 |
| language |
English |
| mega_collection |
American Physiological Society (CrossRef) |
| match_str |
clouse1993topographyofnormalandhighamplitudeesophagealperistalsis |
| publishDateSort |
1993 |
| publisher |
American Physiological Society |
| recordtype |
ai |
| record_format |
ai |
| series |
American Journal of Physiology-Gastrointestinal and Liver Physiology |
| source_id |
49 |
| title |
Topography of normal and high-amplitude esophageal peristalsis |
| title_unstemmed |
Topography of normal and high-amplitude esophageal peristalsis |
| title_full |
Topography of normal and high-amplitude esophageal peristalsis |
| title_fullStr |
Topography of normal and high-amplitude esophageal peristalsis |
| title_full_unstemmed |
Topography of normal and high-amplitude esophageal peristalsis |
| title_short |
Topography of normal and high-amplitude esophageal peristalsis |
| title_sort |
topography of normal and high-amplitude esophageal peristalsis |
| topic |
Physiology (medical) Gastroenterology Hepatology Physiology |
| url |
http://dx.doi.org/10.1152/ajpgi.1993.265.6.g1098 |
| publishDate |
1993 |
| physical |
G1098-G1107 |
| description |
<jats:p> Topographic plots were created from esophageal manometric tracings in 12 asymptomatic volunteers and 10 symptomatic patients with high-amplitude peristaltic contraction waves (nutcracker esophagus) to identify segmental contraction differences between the two groups. Median waves at each centimeter of esophageal length were spatially interconnected using a computerized gridding and plotting system, and a characteristic peristaltic contraction from the proximal esophageal body through the lower sphincter was constructed for each subject. Contour plots in the volunteers revealed three amplitude troughs dividing the peristaltic contraction into four sequential segments: the skeletal muscle body, the proximal and distal segments of the smooth muscle body, and the lower sphincter region. In nutcracker-esophagus patients, only the first and third troughs could be identified, since augmented contraction in the distal smooth muscle segment blurred separation of the smooth muscle body segments. Volume measurements under the topographic plots showed no significant intergroup differences in contraction of the skeletal muscle region or lower sphincter but modest increase in contraction of the proximal smooth muscle segment [1.7 times normal, 95% confidence interval (CI) 1.2-2.0; P = 0.002 comparing 2 groups] and marked increase in the distal smooth muscle segment (2.7 times normal, 95% CI 2.0-3.3; P < 0.0001). These data indicate that normal peristalsis through the esophageal body and lower sphincter includes four separate contraction segments that can be distinguished with intraluminal manometry and the topographic analysis method. The nutcracker esophagus primarily affects the distal segment in the smooth muscle body. </jats:p> |
| container_issue |
6 |
| container_start_page |
0 |
| container_title |
American Journal of Physiology-Gastrointestinal and Liver Physiology |
| container_volume |
265 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792343175938965511 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T16:47:32.958Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Topography+of+normal+and+high-amplitude+esophageal+peristalsis&rft.date=1993-12-01&genre=article&issn=1522-1547&volume=265&issue=6&pages=G1098-G1107&jtitle=American+Journal+of+Physiology-Gastrointestinal+and+Liver+Physiology&atitle=Topography+of+normal+and+high-amplitude+esophageal+peristalsis&aulast=Staiano&aufirst=A.&rft_id=info%3Adoi%2F10.1152%2Fajpgi.1993.265.6.g1098&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792343175938965511 |
| author | Clouse, R. E., Staiano, A. |
| author_facet | Clouse, R. E., Staiano, A., Clouse, R. E., Staiano, A. |
| author_sort | clouse, r. e. |
| container_issue | 6 |
| container_start_page | 0 |
| container_title | American Journal of Physiology-Gastrointestinal and Liver Physiology |
| container_volume | 265 |
| description | <jats:p> Topographic plots were created from esophageal manometric tracings in 12 asymptomatic volunteers and 10 symptomatic patients with high-amplitude peristaltic contraction waves (nutcracker esophagus) to identify segmental contraction differences between the two groups. Median waves at each centimeter of esophageal length were spatially interconnected using a computerized gridding and plotting system, and a characteristic peristaltic contraction from the proximal esophageal body through the lower sphincter was constructed for each subject. Contour plots in the volunteers revealed three amplitude troughs dividing the peristaltic contraction into four sequential segments: the skeletal muscle body, the proximal and distal segments of the smooth muscle body, and the lower sphincter region. In nutcracker-esophagus patients, only the first and third troughs could be identified, since augmented contraction in the distal smooth muscle segment blurred separation of the smooth muscle body segments. Volume measurements under the topographic plots showed no significant intergroup differences in contraction of the skeletal muscle region or lower sphincter but modest increase in contraction of the proximal smooth muscle segment [1.7 times normal, 95% confidence interval (CI) 1.2-2.0; P = 0.002 comparing 2 groups] and marked increase in the distal smooth muscle segment (2.7 times normal, 95% CI 2.0-3.3; P < 0.0001). These data indicate that normal peristalsis through the esophageal body and lower sphincter includes four separate contraction segments that can be distinguished with intraluminal manometry and the topographic analysis method. The nutcracker esophagus primarily affects the distal segment in the smooth muscle body. </jats:p> |
| doi_str_mv | 10.1152/ajpgi.1993.265.6.g1098 |
| facet_avail | Online |
| finc_class_facet | Biologie, Medizin |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTE1Mi9hanBnaS4xOTkzLjI2NS42LmcxMDk4 |
| imprint | American Physiological Society, 1993 |
| imprint_str_mv | American Physiological Society, 1993 |
| institution | DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-14 |
| issn | 0193-1857, 1522-1547 |
| issn_str_mv | 0193-1857, 1522-1547 |
| language | English |
| last_indexed | 2024-03-01T16:47:32.958Z |
| match_str | clouse1993topographyofnormalandhighamplitudeesophagealperistalsis |
| mega_collection | American Physiological Society (CrossRef) |
| physical | G1098-G1107 |
| publishDate | 1993 |
| publishDateSort | 1993 |
| publisher | American Physiological Society |
| record_format | ai |
| recordtype | ai |
| series | American Journal of Physiology-Gastrointestinal and Liver Physiology |
| source_id | 49 |
| spelling | Clouse, R. E. Staiano, A. 0193-1857 1522-1547 American Physiological Society Physiology (medical) Gastroenterology Hepatology Physiology http://dx.doi.org/10.1152/ajpgi.1993.265.6.g1098 <jats:p> Topographic plots were created from esophageal manometric tracings in 12 asymptomatic volunteers and 10 symptomatic patients with high-amplitude peristaltic contraction waves (nutcracker esophagus) to identify segmental contraction differences between the two groups. Median waves at each centimeter of esophageal length were spatially interconnected using a computerized gridding and plotting system, and a characteristic peristaltic contraction from the proximal esophageal body through the lower sphincter was constructed for each subject. Contour plots in the volunteers revealed three amplitude troughs dividing the peristaltic contraction into four sequential segments: the skeletal muscle body, the proximal and distal segments of the smooth muscle body, and the lower sphincter region. In nutcracker-esophagus patients, only the first and third troughs could be identified, since augmented contraction in the distal smooth muscle segment blurred separation of the smooth muscle body segments. Volume measurements under the topographic plots showed no significant intergroup differences in contraction of the skeletal muscle region or lower sphincter but modest increase in contraction of the proximal smooth muscle segment [1.7 times normal, 95% confidence interval (CI) 1.2-2.0; P = 0.002 comparing 2 groups] and marked increase in the distal smooth muscle segment (2.7 times normal, 95% CI 2.0-3.3; P < 0.0001). These data indicate that normal peristalsis through the esophageal body and lower sphincter includes four separate contraction segments that can be distinguished with intraluminal manometry and the topographic analysis method. The nutcracker esophagus primarily affects the distal segment in the smooth muscle body. </jats:p> Topography of normal and high-amplitude esophageal peristalsis American Journal of Physiology-Gastrointestinal and Liver Physiology |
| spellingShingle | Clouse, R. E., Staiano, A., American Journal of Physiology-Gastrointestinal and Liver Physiology, Topography of normal and high-amplitude esophageal peristalsis, Physiology (medical), Gastroenterology, Hepatology, Physiology |
| title | Topography of normal and high-amplitude esophageal peristalsis |
| title_full | Topography of normal and high-amplitude esophageal peristalsis |
| title_fullStr | Topography of normal and high-amplitude esophageal peristalsis |
| title_full_unstemmed | Topography of normal and high-amplitude esophageal peristalsis |
| title_short | Topography of normal and high-amplitude esophageal peristalsis |
| title_sort | topography of normal and high-amplitude esophageal peristalsis |
| title_unstemmed | Topography of normal and high-amplitude esophageal peristalsis |
| topic | Physiology (medical), Gastroenterology, Hepatology, Physiology |
| url | http://dx.doi.org/10.1152/ajpgi.1993.265.6.g1098 |