Eintrag weiter verarbeiten
More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors
Gespeichert in:
| Zeitschriftentitel: | Med. Chem. Commun. |
|---|---|
| Personen und Körperschaften: | , , , , , , , |
| In: | Med. Chem. Commun., 5, 2014, 4, S. 507-511 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Royal Society of Chemistry (RSC)
|
| Schlagwörter: |
| author_facet |
Li, Wei Wan, Xiaobo Zeng, Fanqi Xie, Yuting Wang, Yanli Zhang, Wei Li, Li Huang, Niu Li, Wei Wan, Xiaobo Zeng, Fanqi Xie, Yuting Wang, Yanli Zhang, Wei Li, Li Huang, Niu |
|---|---|
| author |
Li, Wei Wan, Xiaobo Zeng, Fanqi Xie, Yuting Wang, Yanli Zhang, Wei Li, Li Huang, Niu |
| spellingShingle |
Li, Wei Wan, Xiaobo Zeng, Fanqi Xie, Yuting Wang, Yanli Zhang, Wei Li, Li Huang, Niu Med. Chem. Commun. More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors Pharmaceutical Science Biochemistry Drug Discovery Molecular Medicine Pharmacology Organic Chemistry |
| author_sort |
li, wei |
| spelling |
Li, Wei Wan, Xiaobo Zeng, Fanqi Xie, Yuting Wang, Yanli Zhang, Wei Li, Li Huang, Niu 2040-2503 2040-2511 Royal Society of Chemistry (RSC) Pharmaceutical Science Biochemistry Drug Discovery Molecular Medicine Pharmacology Organic Chemistry http://dx.doi.org/10.1039/c4md00030g <p>A structure-based hierarchical virtual screening method was employed to identify a GPCR ligand, thioridazine, as a Pim-1 kinase inhibitor.</p> More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors Med. Chem. Commun. |
| doi_str_mv |
10.1039/c4md00030g |
| facet_avail |
Online |
| finc_class_facet |
Chemie und Pharmazie Medizin |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAzOS9jNG1kMDAwMzBn |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAzOS9jNG1kMDAwMzBn |
| institution |
DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-D161 DE-Zi4 DE-Gla1 DE-15 DE-Pl11 DE-Rs1 DE-14 DE-105 DE-Ch1 |
| imprint |
Royal Society of Chemistry (RSC), 2014 |
| imprint_str_mv |
Royal Society of Chemistry (RSC), 2014 |
| issn |
2040-2503 2040-2511 |
| issn_str_mv |
2040-2503 2040-2511 |
| language |
English |
| mega_collection |
Royal Society of Chemistry (RSC) (CrossRef) |
| match_str |
li2014morethanjustagpcrligandstructurebaseddiscoveryofthioridazinederivativesaspim1kinaseinhibitors |
| publishDateSort |
2014 |
| publisher |
Royal Society of Chemistry (RSC) |
| recordtype |
ai |
| record_format |
ai |
| series |
Med. Chem. Commun. |
| source_id |
49 |
| title |
More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors |
| title_unstemmed |
More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors |
| title_full |
More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors |
| title_fullStr |
More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors |
| title_full_unstemmed |
More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors |
| title_short |
More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors |
| title_sort |
more than just a gpcr ligand: structure-based discovery of thioridazine derivatives as pim-1 kinase inhibitors |
| topic |
Pharmaceutical Science Biochemistry Drug Discovery Molecular Medicine Pharmacology Organic Chemistry |
| url |
http://dx.doi.org/10.1039/c4md00030g |
| publishDate |
2014 |
| physical |
507-511 |
| description |
<p>A structure-based hierarchical virtual screening method was employed to identify a GPCR ligand, thioridazine, as a Pim-1 kinase inhibitor.</p> |
| container_issue |
4 |
| container_start_page |
507 |
| container_title |
Med. Chem. Commun. |
| container_volume |
5 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792343128387092480 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T16:46:46.93Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=More+than+just+a+GPCR+ligand%3A+structure-based+discovery+of+thioridazine+derivatives+as+Pim-1+kinase+inhibitors&rft.date=2014-01-01&genre=article&issn=2040-2511&volume=5&issue=4&spage=507&epage=511&pages=507-511&jtitle=Med.+Chem.+Commun.&atitle=More+than+just+a+GPCR+ligand%3A+structure-based+discovery+of+thioridazine+derivatives+as+Pim-1+kinase+inhibitors&aulast=Huang&aufirst=Niu&rft_id=info%3Adoi%2F10.1039%2Fc4md00030g&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792343128387092480 |
| author | Li, Wei, Wan, Xiaobo, Zeng, Fanqi, Xie, Yuting, Wang, Yanli, Zhang, Wei, Li, Li, Huang, Niu |
| author_facet | Li, Wei, Wan, Xiaobo, Zeng, Fanqi, Xie, Yuting, Wang, Yanli, Zhang, Wei, Li, Li, Huang, Niu, Li, Wei, Wan, Xiaobo, Zeng, Fanqi, Xie, Yuting, Wang, Yanli, Zhang, Wei, Li, Li, Huang, Niu |
| author_sort | li, wei |
| container_issue | 4 |
| container_start_page | 507 |
| container_title | Med. Chem. Commun. |
| container_volume | 5 |
| description | <p>A structure-based hierarchical virtual screening method was employed to identify a GPCR ligand, thioridazine, as a Pim-1 kinase inhibitor.</p> |
| doi_str_mv | 10.1039/c4md00030g |
| facet_avail | Online |
| finc_class_facet | Chemie und Pharmazie, Medizin |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAzOS9jNG1kMDAwMzBn |
| imprint | Royal Society of Chemistry (RSC), 2014 |
| imprint_str_mv | Royal Society of Chemistry (RSC), 2014 |
| institution | DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Zi4, DE-Gla1, DE-15, DE-Pl11, DE-Rs1, DE-14, DE-105, DE-Ch1 |
| issn | 2040-2503, 2040-2511 |
| issn_str_mv | 2040-2503, 2040-2511 |
| language | English |
| last_indexed | 2024-03-01T16:46:46.93Z |
| match_str | li2014morethanjustagpcrligandstructurebaseddiscoveryofthioridazinederivativesaspim1kinaseinhibitors |
| mega_collection | Royal Society of Chemistry (RSC) (CrossRef) |
| physical | 507-511 |
| publishDate | 2014 |
| publishDateSort | 2014 |
| publisher | Royal Society of Chemistry (RSC) |
| record_format | ai |
| recordtype | ai |
| series | Med. Chem. Commun. |
| source_id | 49 |
| spelling | Li, Wei Wan, Xiaobo Zeng, Fanqi Xie, Yuting Wang, Yanli Zhang, Wei Li, Li Huang, Niu 2040-2503 2040-2511 Royal Society of Chemistry (RSC) Pharmaceutical Science Biochemistry Drug Discovery Molecular Medicine Pharmacology Organic Chemistry http://dx.doi.org/10.1039/c4md00030g <p>A structure-based hierarchical virtual screening method was employed to identify a GPCR ligand, thioridazine, as a Pim-1 kinase inhibitor.</p> More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors Med. Chem. Commun. |
| spellingShingle | Li, Wei, Wan, Xiaobo, Zeng, Fanqi, Xie, Yuting, Wang, Yanli, Zhang, Wei, Li, Li, Huang, Niu, Med. Chem. Commun., More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors, Pharmaceutical Science, Biochemistry, Drug Discovery, Molecular Medicine, Pharmacology, Organic Chemistry |
| title | More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors |
| title_full | More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors |
| title_fullStr | More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors |
| title_full_unstemmed | More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors |
| title_short | More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors |
| title_sort | more than just a gpcr ligand: structure-based discovery of thioridazine derivatives as pim-1 kinase inhibitors |
| title_unstemmed | More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors |
| topic | Pharmaceutical Science, Biochemistry, Drug Discovery, Molecular Medicine, Pharmacology, Organic Chemistry |
| url | http://dx.doi.org/10.1039/c4md00030g |