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Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity
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| Zeitschriftentitel: | Journal of Cutaneous Pathology |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Journal of Cutaneous Pathology, 29, 2002, 9, S. 534-539 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Diaz‐Cascajo, C. Schaefer, D. Borghi, S. Diaz‐Cascajo, C. Schaefer, D. Borghi, S. |
|---|---|
| author |
Diaz‐Cascajo, C. Schaefer, D. Borghi, S. |
| spellingShingle |
Diaz‐Cascajo, C. Schaefer, D. Borghi, S. Journal of Cutaneous Pathology Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity Dermatology Histology Pathology and Forensic Medicine |
| author_sort |
diaz‐cascajo, c. |
| spelling |
Diaz‐Cascajo, C. Schaefer, D. Borghi, S. 0303-6987 1600-0560 Wiley Dermatology Histology Pathology and Forensic Medicine http://dx.doi.org/10.1034/j.1600-0560.2002.290905.x <jats:p><jats:bold>Background: </jats:bold> Angiofibroblastoma of the skin is a recently described benign tumor with fibroblastic differentiation. The tumor is composed of stellate and spindle fibroblasts embedded in a fibromyxoid and fibrous matrix that contains numerous capillary‐sized blood vessels.</jats:p><jats:p><jats:bold>Methods: </jats:bold> All cases of fibromyxoid tumors of the skin from the files of two dermatopathologic centers and from consultation cases, together with clinical data and histopathologic specimens, were reviewed. Additionally, immunohistochemical studies were performed in all cases.</jats:p><jats:p><jats:bold>Results: </jats:bold> Seven cases of angiofibroblastoma of the skin were found, including two cases previously reported. All cases showed similar histopathologic findings. The morphologic versatility of fibroblasts, however, explains some of the microscopic variations that were observed in three cases of this series. Immunohistochemical studies support the fibroblastic nature of the neoplasms.</jats:p><jats:p><jats:bold>Conclusions: </jats:bold> Our series provides data suggesting that angiofibroblastoma of the skin represents a distinctive entity, which should be considered in the differential diagnosis of other fibromyxoid tumors of the skin.</jats:p> Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity Journal of Cutaneous Pathology |
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Journal of Cutaneous Pathology |
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49 |
| title |
Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| title_unstemmed |
Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| title_full |
Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| title_fullStr |
Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| title_full_unstemmed |
Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| title_short |
Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| title_sort |
angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| topic |
Dermatology Histology Pathology and Forensic Medicine |
| url |
http://dx.doi.org/10.1034/j.1600-0560.2002.290905.x |
| publishDate |
2002 |
| physical |
534-539 |
| description |
<jats:p><jats:bold>Background: </jats:bold> Angiofibroblastoma of the skin is a recently described benign tumor with fibroblastic differentiation. The tumor is composed of stellate and spindle fibroblasts embedded in a fibromyxoid and fibrous matrix that contains numerous capillary‐sized blood vessels.</jats:p><jats:p><jats:bold>Methods: </jats:bold> All cases of fibromyxoid tumors of the skin from the files of two dermatopathologic centers and from consultation cases, together with clinical data and histopathologic specimens, were reviewed. Additionally, immunohistochemical studies were performed in all cases.</jats:p><jats:p><jats:bold>Results: </jats:bold> Seven cases of angiofibroblastoma of the skin were found, including two cases previously reported. All cases showed similar histopathologic findings. The morphologic versatility of fibroblasts, however, explains some of the microscopic variations that were observed in three cases of this series. Immunohistochemical studies support the fibroblastic nature of the neoplasms.</jats:p><jats:p><jats:bold>Conclusions: </jats:bold> Our series provides data suggesting that angiofibroblastoma of the skin represents a distinctive entity, which should be considered in the differential diagnosis of other fibromyxoid tumors of the skin.</jats:p> |
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| author | Diaz‐Cascajo, C., Schaefer, D., Borghi, S. |
| author_facet | Diaz‐Cascajo, C., Schaefer, D., Borghi, S., Diaz‐Cascajo, C., Schaefer, D., Borghi, S. |
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| description | <jats:p><jats:bold>Background: </jats:bold> Angiofibroblastoma of the skin is a recently described benign tumor with fibroblastic differentiation. The tumor is composed of stellate and spindle fibroblasts embedded in a fibromyxoid and fibrous matrix that contains numerous capillary‐sized blood vessels.</jats:p><jats:p><jats:bold>Methods: </jats:bold> All cases of fibromyxoid tumors of the skin from the files of two dermatopathologic centers and from consultation cases, together with clinical data and histopathologic specimens, were reviewed. Additionally, immunohistochemical studies were performed in all cases.</jats:p><jats:p><jats:bold>Results: </jats:bold> Seven cases of angiofibroblastoma of the skin were found, including two cases previously reported. All cases showed similar histopathologic findings. The morphologic versatility of fibroblasts, however, explains some of the microscopic variations that were observed in three cases of this series. Immunohistochemical studies support the fibroblastic nature of the neoplasms.</jats:p><jats:p><jats:bold>Conclusions: </jats:bold> Our series provides data suggesting that angiofibroblastoma of the skin represents a distinctive entity, which should be considered in the differential diagnosis of other fibromyxoid tumors of the skin.</jats:p> |
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| spelling | Diaz‐Cascajo, C. Schaefer, D. Borghi, S. 0303-6987 1600-0560 Wiley Dermatology Histology Pathology and Forensic Medicine http://dx.doi.org/10.1034/j.1600-0560.2002.290905.x <jats:p><jats:bold>Background: </jats:bold> Angiofibroblastoma of the skin is a recently described benign tumor with fibroblastic differentiation. The tumor is composed of stellate and spindle fibroblasts embedded in a fibromyxoid and fibrous matrix that contains numerous capillary‐sized blood vessels.</jats:p><jats:p><jats:bold>Methods: </jats:bold> All cases of fibromyxoid tumors of the skin from the files of two dermatopathologic centers and from consultation cases, together with clinical data and histopathologic specimens, were reviewed. Additionally, immunohistochemical studies were performed in all cases.</jats:p><jats:p><jats:bold>Results: </jats:bold> Seven cases of angiofibroblastoma of the skin were found, including two cases previously reported. All cases showed similar histopathologic findings. The morphologic versatility of fibroblasts, however, explains some of the microscopic variations that were observed in three cases of this series. Immunohistochemical studies support the fibroblastic nature of the neoplasms.</jats:p><jats:p><jats:bold>Conclusions: </jats:bold> Our series provides data suggesting that angiofibroblastoma of the skin represents a distinctive entity, which should be considered in the differential diagnosis of other fibromyxoid tumors of the skin.</jats:p> Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity Journal of Cutaneous Pathology |
| spellingShingle | Diaz‐Cascajo, C., Schaefer, D., Borghi, S., Journal of Cutaneous Pathology, Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity, Dermatology, Histology, Pathology and Forensic Medicine |
| title | Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| title_full | Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| title_fullStr | Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| title_full_unstemmed | Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| title_short | Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| title_sort | angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| title_unstemmed | Angiofibroblastoma of the skin: a report of seven cases in support of a distinctive entity |
| topic | Dermatology, Histology, Pathology and Forensic Medicine |
| url | http://dx.doi.org/10.1034/j.1600-0560.2002.290905.x |