Eintrag weiter verarbeiten
Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children
Gespeichert in:
| Zeitschriftentitel: | British Journal of Nutrition |
|---|---|
| Personen und Körperschaften: | , , |
| In: | British Journal of Nutrition, 102, 2009, 3, S. 407-412 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Cambridge University Press (CUP)
|
| Schlagwörter: |
| author_facet |
Eriksson, Susanne Mellström, Dan Strandvik, Birgitta Eriksson, Susanne Mellström, Dan Strandvik, Birgitta |
|---|---|
| author |
Eriksson, Susanne Mellström, Dan Strandvik, Birgitta |
| spellingShingle |
Eriksson, Susanne Mellström, Dan Strandvik, Birgitta British Journal of Nutrition Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children Nutrition and Dietetics Medicine (miscellaneous) |
| author_sort |
eriksson, susanne |
| spelling |
Eriksson, Susanne Mellström, Dan Strandvik, Birgitta 0007-1145 1475-2662 Cambridge University Press (CUP) Nutrition and Dietetics Medicine (miscellaneous) http://dx.doi.org/10.1017/s0007114508190286 <jats:p>Animal studies have shown that fatty acids (FA) are important for normal bone development. Human data are scanty and mostly related to diseases. We hypothesised that serum FA pattern might be related to bone mineralisation in healthy children. Serum phospholipid FA pattern was studied in relation to bone parameters in eighty-five healthy Caucasian 8-year-olds. Dual-energy X-ray absorptiometry and blood sampling for analysis of serum phospholipid FA by capillary GLC were performed on the same day. SFA concentrations were associated with bone mineral density (BMD) of the hip, lumbar spine and total body. There was a general trend that linoleic acid (LA; 18 : 2<jats:italic>n</jats:italic>-6) was negatively associated with BMD, since that was found both for the LA concentration, the total <jats:italic>n</jats:italic>-6 concentration and the ratio of <jats:italic>n</jats:italic>-6:<jats:italic>n</jats:italic>-3 FA. Arachidonic acid (AA; 20 : 4<jats:italic>n</jats:italic>-6) was positively correlated with bone mineral content (BMC) and BMD of total body, as was the corresponding <jats:italic>z</jats:italic>-score and the AA:LA ratio. Both saturated and polyunsaturated serum phospholipid FA were associated with BMC and BMD in healthy children. LA and AA were found to inversely influence bone mineralisation and the association with the <jats:italic>n</jats:italic>-6:<jats:italic>n</jats:italic>-3 ratio suggested that this balance might also be of importance. The general trend of a negative influence of high <jats:italic>n</jats:italic>-6 FA concentrations on bone mineralisation might be of concern in relation to the changes in the Western diet. Longitudinal studies are necessary to verify if different bone compartments and different grades of modelling are related to different FA patterns.</jats:p> Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children British Journal of Nutrition |
| doi_str_mv |
10.1017/s0007114508190286 |
| facet_avail |
Online Free |
| finc_class_facet |
Medizin |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAxNy9zMDAwNzExNDUwODE5MDI4Ng |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAxNy9zMDAwNzExNDUwODE5MDI4Ng |
| institution |
DE-105 DE-14 DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 |
| imprint |
Cambridge University Press (CUP), 2009 |
| imprint_str_mv |
Cambridge University Press (CUP), 2009 |
| issn |
0007-1145 1475-2662 |
| issn_str_mv |
0007-1145 1475-2662 |
| language |
English |
| mega_collection |
Cambridge University Press (CUP) (CrossRef) |
| match_str |
eriksson2009fattyacidpatterninserumisassociatedwithbonemineralisationinhealthy8yearoldchildren |
| publishDateSort |
2009 |
| publisher |
Cambridge University Press (CUP) |
| recordtype |
ai |
| record_format |
ai |
| series |
British Journal of Nutrition |
| source_id |
49 |
| title |
Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| title_unstemmed |
Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| title_full |
Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| title_fullStr |
Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| title_full_unstemmed |
Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| title_short |
Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| title_sort |
fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| topic |
Nutrition and Dietetics Medicine (miscellaneous) |
| url |
http://dx.doi.org/10.1017/s0007114508190286 |
| publishDate |
2009 |
| physical |
407-412 |
| description |
<jats:p>Animal studies have shown that fatty acids (FA) are important for normal bone development. Human data are scanty and mostly related to diseases. We hypothesised that serum FA pattern might be related to bone mineralisation in healthy children. Serum phospholipid FA pattern was studied in relation to bone parameters in eighty-five healthy Caucasian 8-year-olds. Dual-energy X-ray absorptiometry and blood sampling for analysis of serum phospholipid FA by capillary GLC were performed on the same day. SFA concentrations were associated with bone mineral density (BMD) of the hip, lumbar spine and total body. There was a general trend that linoleic acid (LA; 18 : 2<jats:italic>n</jats:italic>-6) was negatively associated with BMD, since that was found both for the LA concentration, the total <jats:italic>n</jats:italic>-6 concentration and the ratio of <jats:italic>n</jats:italic>-6:<jats:italic>n</jats:italic>-3 FA. Arachidonic acid (AA; 20 : 4<jats:italic>n</jats:italic>-6) was positively correlated with bone mineral content (BMC) and BMD of total body, as was the corresponding <jats:italic>z</jats:italic>-score and the AA:LA ratio. Both saturated and polyunsaturated serum phospholipid FA were associated with BMC and BMD in healthy children. LA and AA were found to inversely influence bone mineralisation and the association with the <jats:italic>n</jats:italic>-6:<jats:italic>n</jats:italic>-3 ratio suggested that this balance might also be of importance. The general trend of a negative influence of high <jats:italic>n</jats:italic>-6 FA concentrations on bone mineralisation might be of concern in relation to the changes in the Western diet. Longitudinal studies are necessary to verify if different bone compartments and different grades of modelling are related to different FA patterns.</jats:p> |
| container_issue |
3 |
| container_start_page |
407 |
| container_title |
British Journal of Nutrition |
| container_volume |
102 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792344055790698502 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T17:01:31.22Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Fatty+acid+pattern+in+serum+is+associated+with+bone+mineralisation+in+healthy+8-year-old+children&rft.date=2009-01-28&genre=article&issn=1475-2662&volume=102&issue=3&spage=407&epage=412&pages=407-412&jtitle=British+Journal+of+Nutrition&atitle=Fatty+acid+pattern+in+serum+is+associated+with+bone+mineralisation+in+healthy+8-year-old+children&aulast=Strandvik&aufirst=Birgitta&rft_id=info%3Adoi%2F10.1017%2Fs0007114508190286&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792344055790698502 |
| author | Eriksson, Susanne, Mellström, Dan, Strandvik, Birgitta |
| author_facet | Eriksson, Susanne, Mellström, Dan, Strandvik, Birgitta, Eriksson, Susanne, Mellström, Dan, Strandvik, Birgitta |
| author_sort | eriksson, susanne |
| container_issue | 3 |
| container_start_page | 407 |
| container_title | British Journal of Nutrition |
| container_volume | 102 |
| description | <jats:p>Animal studies have shown that fatty acids (FA) are important for normal bone development. Human data are scanty and mostly related to diseases. We hypothesised that serum FA pattern might be related to bone mineralisation in healthy children. Serum phospholipid FA pattern was studied in relation to bone parameters in eighty-five healthy Caucasian 8-year-olds. Dual-energy X-ray absorptiometry and blood sampling for analysis of serum phospholipid FA by capillary GLC were performed on the same day. SFA concentrations were associated with bone mineral density (BMD) of the hip, lumbar spine and total body. There was a general trend that linoleic acid (LA; 18 : 2<jats:italic>n</jats:italic>-6) was negatively associated with BMD, since that was found both for the LA concentration, the total <jats:italic>n</jats:italic>-6 concentration and the ratio of <jats:italic>n</jats:italic>-6:<jats:italic>n</jats:italic>-3 FA. Arachidonic acid (AA; 20 : 4<jats:italic>n</jats:italic>-6) was positively correlated with bone mineral content (BMC) and BMD of total body, as was the corresponding <jats:italic>z</jats:italic>-score and the AA:LA ratio. Both saturated and polyunsaturated serum phospholipid FA were associated with BMC and BMD in healthy children. LA and AA were found to inversely influence bone mineralisation and the association with the <jats:italic>n</jats:italic>-6:<jats:italic>n</jats:italic>-3 ratio suggested that this balance might also be of importance. The general trend of a negative influence of high <jats:italic>n</jats:italic>-6 FA concentrations on bone mineralisation might be of concern in relation to the changes in the Western diet. Longitudinal studies are necessary to verify if different bone compartments and different grades of modelling are related to different FA patterns.</jats:p> |
| doi_str_mv | 10.1017/s0007114508190286 |
| facet_avail | Online, Free |
| finc_class_facet | Medizin |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAxNy9zMDAwNzExNDUwODE5MDI4Ng |
| imprint | Cambridge University Press (CUP), 2009 |
| imprint_str_mv | Cambridge University Press (CUP), 2009 |
| institution | DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1 |
| issn | 0007-1145, 1475-2662 |
| issn_str_mv | 0007-1145, 1475-2662 |
| language | English |
| last_indexed | 2024-03-01T17:01:31.22Z |
| match_str | eriksson2009fattyacidpatterninserumisassociatedwithbonemineralisationinhealthy8yearoldchildren |
| mega_collection | Cambridge University Press (CUP) (CrossRef) |
| physical | 407-412 |
| publishDate | 2009 |
| publishDateSort | 2009 |
| publisher | Cambridge University Press (CUP) |
| record_format | ai |
| recordtype | ai |
| series | British Journal of Nutrition |
| source_id | 49 |
| spelling | Eriksson, Susanne Mellström, Dan Strandvik, Birgitta 0007-1145 1475-2662 Cambridge University Press (CUP) Nutrition and Dietetics Medicine (miscellaneous) http://dx.doi.org/10.1017/s0007114508190286 <jats:p>Animal studies have shown that fatty acids (FA) are important for normal bone development. Human data are scanty and mostly related to diseases. We hypothesised that serum FA pattern might be related to bone mineralisation in healthy children. Serum phospholipid FA pattern was studied in relation to bone parameters in eighty-five healthy Caucasian 8-year-olds. Dual-energy X-ray absorptiometry and blood sampling for analysis of serum phospholipid FA by capillary GLC were performed on the same day. SFA concentrations were associated with bone mineral density (BMD) of the hip, lumbar spine and total body. There was a general trend that linoleic acid (LA; 18 : 2<jats:italic>n</jats:italic>-6) was negatively associated with BMD, since that was found both for the LA concentration, the total <jats:italic>n</jats:italic>-6 concentration and the ratio of <jats:italic>n</jats:italic>-6:<jats:italic>n</jats:italic>-3 FA. Arachidonic acid (AA; 20 : 4<jats:italic>n</jats:italic>-6) was positively correlated with bone mineral content (BMC) and BMD of total body, as was the corresponding <jats:italic>z</jats:italic>-score and the AA:LA ratio. Both saturated and polyunsaturated serum phospholipid FA were associated with BMC and BMD in healthy children. LA and AA were found to inversely influence bone mineralisation and the association with the <jats:italic>n</jats:italic>-6:<jats:italic>n</jats:italic>-3 ratio suggested that this balance might also be of importance. The general trend of a negative influence of high <jats:italic>n</jats:italic>-6 FA concentrations on bone mineralisation might be of concern in relation to the changes in the Western diet. Longitudinal studies are necessary to verify if different bone compartments and different grades of modelling are related to different FA patterns.</jats:p> Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children British Journal of Nutrition |
| spellingShingle | Eriksson, Susanne, Mellström, Dan, Strandvik, Birgitta, British Journal of Nutrition, Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children, Nutrition and Dietetics, Medicine (miscellaneous) |
| title | Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| title_full | Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| title_fullStr | Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| title_full_unstemmed | Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| title_short | Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| title_sort | fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| title_unstemmed | Fatty acid pattern in serum is associated with bone mineralisation in healthy 8-year-old children |
| topic | Nutrition and Dietetics, Medicine (miscellaneous) |
| url | http://dx.doi.org/10.1017/s0007114508190286 |